STOCK TITAN

Castle Biosciences CEO sells 18,560 shares

CASTLE BIOSCIENCES INC (CSTL) CEO and director Derek J. Maetzold reported an option exercise and related share sales.

(Very High)
(Negative)
Form Type
4

Rhea-AI Filing Summary

CASTLE BIOSCIENCES INC (CSTL) CEO and director Derek J. Maetzold reported an option exercise and related share sales. He exercised a stock option for 12,428 shares of Common Stock at an exercise price of $2.39 per share, from a fully vested option expiring May 9, 2028, leaving 25,329 option shares outstanding. On the same date, entities associated with him sold an aggregate of 18,560 shares of Common Stock, including direct holdings and shares held through several family and grantor retained annuity trusts, at weighted-average prices of approximately $33.14 and $33.88 per share. All transactions were made pursuant to a Rule 10b5-1 trading plan adopted on December 3, 2025.

Positive

  • None.

Negative

  • None.

Insights

Analyzing...

Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 18,560 shs ($616K)
Approx. gross sale proceeds $616K
Approx. exercise cost $30K
Type Security Shares Price Value
Exercise Stock option (right to buy) F1, F14 12,428 $0.00 $0.00
Exercise Common Stock F1 12,428 $2.39 $30K
Sale Common Stock F1, F2 11,472 $33.14 $380K
Sale Common Stock F1, F2, F3 2,505 $33.14 $83K
Sale Common Stock F1, F2, F4 2,129 $33.14 $71K
Sale Common Stock F1, F2, F5 257 $33.14 $9K
Sale Common Stock F1, F2, F6 257 $33.14 $9K
Sale Common Stock F1, F2, F7 257 $33.14 $9K
Sale Common Stock F1, F2, F8 257 $33.14 $9K
Sale Common Stock F1, F9 956 $33.88 $32K
Sale Common Stock F1, F9, F3 209 $33.88 $7K
Sale Common Stock F1, F9, F4 177 $33.88 $6K
Sale Common Stock F1, F9, F5 21 $33.88 $711.48
Sale Common Stock F1, F9, F6 21 $33.88 $711.48
Sale Common Stock F1, F9, F7 21 $33.88 $711.48
Sale Common Stock F1, F9, F8 21 $33.88 $711.48
holding Common Stock F10 -- -- --
holding Common Stock F11 -- -- --
holding Common Stock F12 -- -- --
holding Common Stock F13 -- -- --
Holdings After Transaction: Stock option (right to buy) — 25,329 contracts (Direct); Common Stock — 21,479 shares (Direct); Common Stock — 17,641 shares (Indirect, By The Maetzold Descendants 2020 Trust); Common Stock — 14,995 shares (Indirect, By Derek Maetzold 2020 Irrevocable Trust); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold); Common Stock — 11,963 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 6); Common Stock — 27,862 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 7); Common Stock — 40,935 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 8); Common Stock — 23,216 shares (Indirect, DJM Grantor Retained Annuity Trust No. 9)
Footnotes (14)
  1. F1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
  2. F2. This transaction was executed in multiple trades at prices ranging from $32.78 to $33.70, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  3. F3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
  4. F4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
  5. F5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
  6. F6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  7. F7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  8. F8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  9. F9. This transaction was executed in multiple trades at prices ranging from $33.78 to $33.97, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  10. F10. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
  11. F11. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
  12. F12. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
  13. F13. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
  14. F14. The shares subject to the option are fully vested.
Option shares exercised 12,428 shares Stock option for Common Stock exercised on August 28, 2026
Exercise price $2.39 per share Exercise price of stock option (right to buy) for 12,428 shares
Option shares remaining 25,329 shares Shares subject to the option following the reported exercise
Total shares sold 18,560 shares Aggregate Common Stock sold across reported sale transactions
Weighted-average sale price block 1 $33.14 per share Sales executed in multiple trades within $32.78–$33.70 range
Weighted-average sale price block 2 $33.88 per share Sales executed in multiple trades within $33.78–$33.97 range
DJM GRAT No. 8 holdings 40,935 shares Common Stock held indirectly by DJM Grantor Retained Annuity Trust No. 8
DJM GRAT No. 7 holdings 27,862 shares Common Stock held indirectly by DJM Grantor Retained Annuity Trust No. 7
Rule 10b5-1 plan regulatory
"These transactions were made pursuant to a Rule 10b5-1 plan adopted"
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 6 of which"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
weighted-average sale price financial
"The price reported above reflects the weighted-average sale price."
stock option (right to buy) financial
"security_title": "Stock option (right to buy)"
irrevocable trust financial
"Held by Derek Maetzold 2020 Irrevocable Trust of which"
An irrevocable trust is a legal arrangement where an owner transfers assets into a separate entity managed by a trustee and gives up the power to modify or reclaim those assets. For investors it matters because putting stock or other holdings into such a trust can change who controls and benefits from the assets, affect taxes and creditor protection, and influence how easy it is to sell or value those holdings—like placing valuables in a locked safe overseen by someone else.

FAQ

What did CSTL CEO Derek Maetzold report in this Form 4?

He reported exercising a stock option for 12,428 shares of Castle Biosciences Common Stock at an exercise price of $2.39 per share and related sales totaling 18,560 shares, including direct holdings and several family and grantor retained annuity trusts.

How many CSTL shares did Derek Maetzold sell on 2026-08-28?

Entities associated with Derek Maetzold sold a total of 18,560 shares of Castle Biosciences Common Stock on August 28, 2026, combining direct sales and sales by multiple family and remainder trusts.

At what prices were the CSTL shares sold in this Form 4?

The reported Common Stock sales occurred in multiple trades at weighted-average prices of $33.14 and $33.88 per share, with underlying trades executed within disclosed price ranges for each weighted-average figure.

What stock option did Derek Maetzold exercise for CSTL?

He exercised a fully vested stock option for 12,428 shares of Castle Biosciences Common Stock at an exercise price of $2.39 per share. After the exercise, 25,329 shares remained subject to that option, which expires on May 9, 2028.

Were the CSTL insider transactions under a Rule 10b5-1 plan?

Yes. The filing states that the reported transactions were made pursuant to a Rule 10b5-1 plan adopted by Derek Maetzold on December 3, 2025, indicating they followed a pre-arranged trading plan.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
08/28/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock08/28/2026M(1)12,428A$2.3933,907D
Common Stock08/28/2026S(1)11,472D$33.14(2)22,435D
Common Stock08/28/2026S(1)2,505D$33.14(2)17,850IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/28/2026S(1)2,129D$33.14(2)15,172IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock08/28/2026S(1)257D$33.14(2)11,277IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock08/28/2026S(1)257D$33.14(2)11,277IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock08/28/2026S(1)257D$33.14(2)11,277IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock08/28/2026S(1)257D$33.14(2)11,277IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock08/28/2026S(1)956D$33.88(9)21,479D
Common Stock08/28/2026S(1)209D$33.88(9)17,641IBy The Maetzold Descendants 2020 Trust(3)
Common Stock08/28/2026S(1)177D$33.88(9)14,995IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock08/28/2026S(1)21D$33.88(9)11,256IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock08/28/2026S(1)21D$33.88(9)11,256IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock08/28/2026S(1)21D$33.88(9)11,256IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock08/28/2026S(1)21D$33.88(9)11,256IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock11,963IBy DJM Grantor Retained Annuity Trust No. 6(10)
Common Stock27,862IBy DJM Grantor Retained Annuity Trust No. 7(11)
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8(12)
Common Stock23,216IDJM Grantor Retained Annuity Trust No. 9(13)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3908/28/2026M(1)12,428 (14)05/09/2028Common Stock12,428$025,329D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
2. This transaction was executed in multiple trades at prices ranging from $32.78 to $33.70, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. This transaction was executed in multiple trades at prices ranging from $33.78 to $33.97, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
10. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
11. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
12. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
13. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
14. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact09/01/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)