STOCK TITAN

Castle Biosciences (CSTL) CEO pre-planned sale of 9,836 shares after option exercise

Filing Impact
(Moderate)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

CASTLE BIOSCIENCES INC President & CEO Derek J. Maetzold reported an exercise-and-sell transaction in company stock. On April 6, 2026, he exercised stock options to acquire 6,214 shares of common stock at an exercise price of $2.39 per share, converting previously granted options into shares.

On the same date, Maetzold sold 6,214 directly held shares of common stock at a weighted-average price of about $25.03 per share, along with additional open-market sales through several family and estate-planning trusts totaling 9,836 shares sold overall. According to the filing, these sales were made under a Rule 10b5-1 trading plan adopted on December 3, 2025, indicating they were pre-scheduled rather than opportunistic trades.

After these transactions, Maetzold continues to hold 21,479 shares directly and maintains substantial indirect ownership through multiple trusts, including 48,852 shares in The Maetzold Descendants 2020 Trust and 85,959 shares in DJM Grantor Retained Annuity Trust No. 5, among other vehicles.

Positive

  • None.

Negative

  • None.
Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 9,836 shs ($246K)
Type Security Shares Price Value
Exercise Stock option (right to buy) 6,214 $0.00 --
Exercise Common Stock 6,214 $2.39 $15K
Sale Common Stock 6,214 $25.03 $156K
Sale Common Stock 1,357 $25.03 $34K
Sale Common Stock 1,153 $25.03 $29K
Sale Common Stock 278 $25.03 $7K
Sale Common Stock 278 $25.03 $7K
Sale Common Stock 278 $25.03 $7K
Sale Common Stock 278 $25.03 $7K
holding Common Stock -- -- --
holding Common Stock -- -- --
holding Common Stock -- -- --
Holdings After Transaction: Stock option (right to buy) — 7,518 shares (Direct); Common Stock — 27,693 shares (Direct); Common Stock — 48,852 shares (Indirect, By The Maetzold Descendants 2020 Trust)
Footnotes (1)
  1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025. This transaction was executed in multiple trades at prices ranging from $24.64 to $25.29, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary. The shares subject to the option are fully vested.
Options exercised 6,214 shares Stock option exercise at $2.39 on April 6, 2026
Exercise price $2.39 per share Strike price of stock option exercised for 6,214 shares
Direct shares sold 6,214 shares Common stock sold at weighted-average $25.03 per share
Total shares sold 9,836 shares Aggregate open-market sales including trust-held shares
Sale price $25.03 per share Weighted-average price for CSTL common stock sales
Direct holdings after trade 21,479 shares Common stock directly owned by Maetzold post-transaction
Descendants 2020 Trust holdings 48,852 shares CSTL common stock held by The Maetzold Descendants 2020 Trust
GRAT No. 5 holdings 85,959 shares CSTL common stock held by DJM Grantor Retained Annuity Trust No. 5
Rule 10b5-1 plan regulatory
"These transactions were made pursuant to a Rule 10b5-1 plan adopted..."
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
weighted-average sale price financial
"executed in multiple trades at prices ranging... The price reported above reflects the weighted-average sale price."
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee..."
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
stock option (right to buy) financial
"security_title": "Stock option (right to buy)""
open-market sale financial
"transaction_action": "open-market sale""
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
04/06/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock04/06/2026M(1)6,214A$2.3927,693D
Common Stock04/06/2026S(1)6,214D$25.03(2)21,479D
Common Stock04/06/2026S(1)1,357D$25.03(2)48,852IBy The Maetzold Descendants 2020 Trust(3)
Common Stock04/06/2026S(1)1,153D$25.03(2)41,520IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock04/06/2026S(1)278D$25.03(2)2,780IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock04/06/2026S(1)278D$25.03(2)2,780IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock04/06/2026S(1)278D$25.03(2)2,780IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock04/06/2026S(1)278D$25.03(2)2,780IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock85,959IBy DJM Grantor Retained Annuity Trust No. 5(9)
Common Stock18,718IBy DJM Grantor Retained Annuity Trust No. 6(10)
Common Stock44,323IBy DJM Grantor Retained Annuity Trust No. 7(11)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3904/06/2026M(1)6,214 (12)11/11/2028Common Stock6,214$07,518D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
2. This transaction was executed in multiple trades at prices ranging from $24.64 to $25.29, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary.
10. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
11. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
12. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact04/08/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did CSTL CEO Derek Maetzold report on April 6, 2026?

He exercised stock options for 6,214 shares at $2.39 and sold a total of 9,836 shares of Castle Biosciences (CSTL) common stock at around $25.03 per share, including direct and trust-held shares.

Was Derek Maetzold’s sale of CSTL shares part of a pre-planned 10b5-1 trading plan?

Yes. The filing states the transactions were made under a Rule 10b5-1 plan adopted on December 3, 2025. Such plans pre-schedule trades, suggesting these sales were routine portfolio management rather than discretionary market-timing decisions.

How many CSTL shares does Derek Maetzold hold directly after these transactions?

Following the reported trades, Derek Maetzold directly holds 21,479 shares of Castle Biosciences common stock. This reflects his remaining personal position after exercising options and selling 6,214 shares in the open market on April 6, 2026.

What CSTL share holdings remain in trusts associated with Derek Maetzold?

Trusts associated with Maetzold still hold significant CSTL stakes, including 48,852 shares in The Maetzold Descendants 2020 Trust and 85,959 shares in DJM Grantor Retained Annuity Trust No. 5, plus additional shares in other remainder and irrevocable trusts.

What price range did CSTL shares sell for in Derek Maetzold’s April 6, 2026 trades?

The reported weighted-average sale price is $25.03 per share. A footnote notes multiple trades executed between $24.64 and $25.29 per share, with detailed trade-by-trade information available upon request to the company or regulators.

What happened to Derek Maetzold’s CSTL stock options in this Form 4 filing?

He exercised fully vested options covering 6,214 shares at an exercise price of $2.39 per share. After this exercise, there are no remaining options from that grant, and the acquired shares were then sold in open-market transactions reported in the same filing.