STOCK TITAN

Castle Biosciences (CSTL) CEO sells 9,836 shares via 10b5-1 plan

Filing Impact
(Moderate)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

Castle Biosciences CEO Derek Maetzold reported option exercises and share sales in Castle Biosciences Inc. common stock. On July 1, 2026, he exercised options for 6,214 shares at $2.39 per share and related entities sold a combined 9,836 shares in open-market transactions at a weighted-average price of $24.29, pursuant to a pre-arranged Rule 10b5-1 plan.

Following these transactions, one direct holding shows 21,479 shares of common stock, and various family and grantor retained annuity trusts associated with Maetzold continue to hold additional indirect positions.

Positive

  • None.

Negative

  • None.

Insights

Pre-planned option exercise with routine net share sale.

Derek Maetzold, CEO of Castle Biosciences, exercised options for 6,214 shares at $2.39 and entities associated with him sold 9,836 shares at a weighted-average price of $24.29 on July 1, 2026.

The filing states these sales were made under a pre-arranged Rule 10b5-1 plan, which typically indicates a scheduled, systematic approach rather than discretionary market timing. After the sale, one direct account shows 21,479 common shares, while several trusts continue to hold sizable indirect stakes.

This pattern—exercise of fully vested options and partial monetization through planned sales—appears routine and does not, by itself, signal a major change in insider conviction. The absence of remaining derivative positions in this filing suggests those particular options have been fully exercised.

Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 9,836 shs ($239K)
Type Security Shares Price Value
Exercise Stock option (right to buy) 6,214 $0.00 --
Exercise Common Stock 6,214 $2.39 $15K
Sale Common Stock 6,214 $24.29 $151K
Sale Common Stock 1,357 $24.29 $33K
Sale Common Stock 1,153 $24.29 $28K
Sale Common Stock 278 $24.29 $7K
Sale Common Stock 278 $24.29 $7K
Sale Common Stock 278 $24.29 $7K
Sale Common Stock 278 $24.29 $7K
holding Common Stock -- -- --
holding Common Stock -- -- --
holding Common Stock -- -- --
Holdings After Transaction: Stock option (right to buy) — 85,667 shares (Direct, null); Common Stock — 27,693 shares (Direct, null); Common Stock — 40,710 shares (Indirect, By The Maetzold Descendants 2020 Trust)
Footnotes (1)
  1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025. This transaction was executed in multiple trades at prices ranging from $23.68 to $24.57, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary. The shares subject to the option are fully vested.
Shares sold 9,836 shares Open-market sales on July 1, 2026
Sale price $24.29 per share Weighted-average sale price for common stock
Options exercised 6,214 shares Common stock acquired via option exercise
Option exercise price $2.39 per share Exercise price of stock option
Direct common shares after 21,479 shares Direct holding following transactions
Remaining options 85,667 options Stock option balance after exercise
Sale date July 1, 2026 Trade and exercise date reported in Form 4
Option expiration May 9, 2028 Expiration date of the exercised option grant
Rule 10b5-1 plan regulatory
"These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person"
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.
stock option (right to buy) financial
"security_title": "Stock option (right to buy)""
weighted-average sale price financial
"executed in multiple trades at prices ranging from $23.68 to $24.57, inclusive. The price reported above reflects the weighted-average sale price."
beneficiaries financial
"of which the Reporting Person is the trustee and his children are beneficiaries."
Beneficiaries are the people or organizations designated to receive benefits, such as money or assets, from a financial arrangement like a trust, insurance policy, or retirement plan. They matter to investors because choosing the right beneficiaries ensures that assets are passed on according to their wishes, providing financial security or support to loved ones when needed. Think of beneficiaries as the intended recipients of a gift or inheritance.
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FAQ

What insider transactions did CSTL CEO Derek Maetzold report on July 1, 2026?

On July 1, 2026, entities associated with CSTL CEO Derek Maetzold sold 9,836 shares of Castle Biosciences common stock and he exercised options for 6,214 shares at $2.39. The sales occurred at a weighted-average price of $24.29 per share.

Were Derek Maetzold’s CSTL share sales made under a Rule 10b5-1 plan?

Yes. The filing states the Castle Biosciences share sales were executed under a Rule 10b5-1 trading plan adopted on December 3, 2025. Such plans pre-schedule trades, making the timing more routine and reducing the signaling value of individual sale dates.

How many Castle Biosciences shares did Derek Maetzold sell and at what price?

Entities associated with Derek Maetzold sold a total of 9,836 Castle Biosciences common shares at a weighted-average price of $24.29 per share. The filing notes execution across multiple trades between $23.68 and $24.57 inclusive.

What stock options did Derek Maetzold exercise in this CSTL Form 4?

He exercised fully vested stock options covering 6,214 Castle Biosciences shares at an exercise price of $2.39 per share. A related derivative table shows 85,667 stock options remaining after the exercise, with an expiration date of May 9, 2028 for that option grant.

What are Derek Maetzold’s direct CSTL shareholdings after these transactions?

After the reported transactions, one direct holding shows 21,479 Castle Biosciences common shares. The Form 4 also lists additional indirect holdings through several family trusts and grantor retained annuity trusts for which Maetzold or his spouse serves as trustee.

Which trusts associated with Derek Maetzold hold CSTL shares?

Indirect holdings include shares held by DJM Grantor Retained Annuity Trusts No. 6, 7 and 8, The Maetzold Descendants 2020 Trust, Derek Maetzold 2020 Irrevocable Trust, and several Maetzold 2018 Remainder Trusts, with Maetzold or his spouse generally serving as trustee.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
07/01/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock07/01/2026M(1)6,214A$2.3927,693D
Common Stock07/01/2026S(1)6,214D$24.29(2)21,479D
Common Stock07/01/2026S(1)1,357D$24.29(2)40,710IBy The Maetzold Descendants 2020 Trust(3)
Common Stock07/01/2026S(1)1,153D$24.29(2)34,602IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock07/01/2026S(1)278D$24.29(2)12,368IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock07/01/2026S(1)278D$24.29(2)12,368IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock07/01/2026S(1)278D$24.29(2)12,368IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock07/01/2026S(1)278D$24.29(2)12,368IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock18,718IBy DJM Grantor Retained Annuity Trust No. 6(9)
Common Stock44,323IBy DJM Grantor Retained Annuity Trust No. 7(10)
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8(11)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3907/01/2026M(1)6,214 (12)05/09/2028Common Stock6,214$085,667D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 3, 2025.
2. This transaction was executed in multiple trades at prices ranging from $23.68 to $24.57, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
10. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
11. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
12. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact07/06/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)