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UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
DC 20549
FORM
8-K
CURRENT
REPORT
Pursuant
to Section 13 or 15(d)
of
the Securities Exchange Act of 1934
August
22, 2025
Date
of Report (date of earliest event reported)

Cyclacel
Pharmaceuticals, Inc.
(Exact
name of Registrant as specified in its charter)
Delaware |
|
0-50626 |
|
91-1707622 |
(State
or other jurisdiction of
incorporation or organization) |
|
(Commission
File Number) |
|
(I.R.S.
Employer
Identification Number) |
Level
10, Tower 11, Avenue 5, No. 8
Jalan
Kerinchi, Kuala Lumpur, Malaysia 592000
(Address
of principal executive offices) (Zip code)
(908)
517-7330
(Registrant’s
telephone number, including area code)
Not
Applicable
(Former
name or former address, if changed since last report)
Check
the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under
any of the following provisions (see General Instruction A.2. below):
☐ |
Written
communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
|
|
☐ |
Soliciting
material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
|
|
☐ |
Pre-commencement
communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
|
|
☐ |
Pre-commencement
communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities
registered pursuant to Section 12(b) of the Act:
Title
of each class |
|
Trading
Symbol(s) |
|
Name
of each exchange on which registered |
Common
Stock, par value $0.001 per share |
|
CYCC |
|
The
Nasdaq Capital Market |
Preferred
Stock, $0.001 par value |
|
CYCCP |
|
The
Nasdaq Capital Market |
Indicate
by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405
of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging
growth company ☐
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item
4.01. Change in Registrant’s Certifying Accountants
(a)
Dismissal of Independent Registered Public Accounting Firm
On
August 22, 2025, the Audit Committee of the Board of Directors (the “Audit Committee”) of Cyclacel Pharmaceuticals, Inc.
(the “Company”) approved the dismissal of Bush & Associates CPA LLP (“Bush”), as the Company’s independent
registered public accounting firm, effective immediately. On August 22, 2025, Bush was informed of such dismissal.
From
November 5, 2024 to August 22, 2025, (i) there were no “disagreements” (as defined in Item 304(a)(1)(iv) of Regulation S-K
and the related instructions to Item 304) with Bush on any matter of accounting principles or practices, financial statement disclosure,
or auditing scope or procedure, which disagreements, if not resolved to the satisfaction of Bush, would have caused Bush to make reference
to the subject matter of such disagreements in connection with its reports on the financial statements for such periods and (ii) there
were no “reportable events” (as defined in Item 304(a)(1)(v) of Regulation S-K) except that Bush advised the Company that
the Company does not currently have sufficient funds to complete development and commercialization and has a limited cash balance as
of December 31, 2024. This raises substantial doubt about the Company’s ability to continue as a going concern.
Bush
has not discussed the reportable event with the Company’s Audit Committee. The Company has authorized Bush to respond fully to
the inquiries of SFAI Malaysia PLT (“SFAI”), as successor auditors, regarding the subject matter of the reportable event.
The
Company provided Bush with a copy of this Current Report on Form 8-K prior to its filing with the Securities and Exchange Commission
(the “SEC”) and requested Bush to furnish a letter addressed to the SEC stating whether it agrees with the above statements.
A copy of Bush’s letter dated August 27, 2025, is filed as Exhibit 16.1 to this Current Report on Form 8-K.
(b)
Engagement of New Independent Registered Public Accounting Firm
On
August 22, 2025, the Audit Committee approved the engagement of SFAI as the Company’s independent registered public accounting
firm for the fiscal year ending December 31, 2025, effective August 23, 2025.
During
the Company’s two most recent fiscal years ended December 31, 2024 and December 31, 2023 and through the date of this Current Report
on Form 8-K, neither the Company nor anyone acting on its behalf consulted with SFAI regarding either: (i) the application of accounting
principles to a specific transaction, either completed or proposed; or the type of audit opinion that might be rendered on the Company’s
financial statements, and neither a written report nor oral advice was provided to the Company that SFAI concluded was an important factor
considered by the Company in reaching a decision as to the accounting, auditing or financial reporting issue; or (ii) any matter that
was the subject of a “disagreement” within the meaning of Item 304(a)(1)(iv) of Regulation S-K and the related instructions
to Item 304 or a “reportable event” within the meaning of Item 304(a)(1)(v) of Regulation S-K.
Item
9.01. Financial Statements and Exhibits.
(d)
Exhibits
Exhibit No. |
|
Description |
16.1 |
|
Letter of Bush & Associates CPA LLP dated August 27, 2025 |
104 |
|
Cover Page Interactive Data File (embedded with the Inline
XBRL document). |
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by
the undersigned, thereunto duly authorized.
Date:
August 28, 2025 |
Cyclacel
Pharmaceuticals, Inc. |
|
|
|
|
By: |
/s/
Datuk Dr. Doris Wong Sing Ee |
|
Name: |
Datuk
Dr. Doris Wong Sing Ee |
|
Title: |
Chief
Executive Officer and Executive Director |