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Cryoport (CYRX) lifts 2026 revenue outlook after 16% Q1 growth

Filing Impact
(High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Cryoport, Inc. reported a strong start to 2026, with first-quarter revenue of $47.8 million, up 16% year-over-year. Life Sciences Services revenue rose to $26.9 million (up 18%), and Life Sciences Products reached $20.9 million (up 15%), driven by demand for cryogenic systems and integrated logistics.

Revenue supporting commercial cell and gene therapies grew 26% to $9.1 million, while clinical trial support revenue increased 18% to $12.9 million. The company supported 766 clinical trials as of March 31, 2026, including 91 in Phase 3 and 21 commercial therapies.

Despite growth, Cryoport posted a loss from continuing operations of $9.4 million and a net loss of $10.5 million, or -$0.25 per share, though adjusted EBITDA from continuing operations improved to -$0.6 million from -$2.8 million. Cash and cash equivalents were $272.9 million with $130.7 million in short-term investments, and full-year 2026 revenue guidance was raised to $192–$196 million.

Positive

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Negative

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Insights

Solid Q1 growth, narrowing losses, and higher 2026 revenue guidance.

Cryoport delivered broad-based top-line growth in Q1 2026. Total revenue rose to $47.8M, up 16%, with Life Sciences Services and Products growing 18% and 15%, respectively. Cell and gene therapy support remained a key driver, growing 26% to $9.1M.

The company is still loss-making, with loss from continuing operations of $9.4M and net loss of $10.5M, but adjusted EBITDA from continuing operations improved to -$0.6M from -$2.8M. Strong liquidity, including $272.9M in cash and $130.7M in short-term investments as of March 31, 2026, provides flexibility.

Operationally, Cryoport supports 766 clinical trials, with 91 in Phase 3, and 21 commercial therapies, illustrating embedded exposure to cell and gene therapy pipelines. Management raised full-year 2026 revenue guidance to $192–$196M, indicating confidence based on current momentum and visibility.

Item 2.02 Results of Operations and Financial Condition Financial
Disclosure of earnings results, typically an earnings press release or preliminary financials.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Total revenue $47.8M Q1 2026, up 16% year-over-year
Life Sciences Services revenue $26.9M Q1 2026, 18% year-over-year growth
Life Sciences Products revenue $20.9M Q1 2026, 15% year-over-year growth
Loss from continuing operations $9.4M Q1 2026 GAAP loss from continuing operations
Net loss per share -$0.25 Q1 2026 basic and diluted EPS
Adjusted EBITDA from continuing ops -$0.6M Q1 2026 vs -$2.8M in Q1 2025
Cash and cash equivalents $272.9M As of March 31, 2026
2026 revenue guidance $192–$196M Full-year 2026 company outlook
adjusted EBITDA from continuing operations financial
"drove a $2.2 million year-over-year improvement in adjusted EBITDA from continuing operations"
discontinued operations financial
"are presented as discontinued operations for all periods and are excluded"
Discontinued operations are parts of a company that it has decided to sell or shut down, and no longer plans to run in the future. This matters to investors because it helps them understand which parts of the business are ongoing and which are being phased out, providing a clearer picture of the company’s current performance and future prospects. Think of it like a store closing a department—it no longer contributes to sales or profits.
Biologics License Applications (BLA) regulatory
"In Q1 2026, four Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred"
A Biologics License Application (BLA) is the formal submission to the U.S. Food and Drug Administration seeking permission to market a biological product, such as a vaccine, therapeutic antibody, or cell therapy. The filing packages clinical trial results, safety data and details about how the product is made; approval is like getting a commercial operating license that lets the company sell the product. Investors watch BLAs closely because approval or rejection directly affects a company’s ability to generate revenue and the stock’s valuation, while the timing and regulatory risks influence investment decisions.
Marketing Authorization Applications (MAA) regulatory
"four Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred"
A marketing authorization application (MAA) is a formal package submitted to a health regulator asking for permission to sell a medicine or medical product; it includes evidence about safety, effectiveness and how the product is made. Investors care because approval is the gate that allows a product to reach the market and generate revenue, so the status and timing of an MAA are key drivers of a company’s future sales prospects and valuation — like applying for a business license before opening a store.
convertible senior notes financial
"Current portion of convertible senior notes, net | | | 185,390"
Convertible senior notes are a type of loan that a company issues to investors, which can be turned into company shares later on. They are called "senior" because they are paid back before other debts if the company runs into trouble. This allows investors to earn interest like a loan but also have the chance to own part of the company if its value rises.
paid-in-kind dividend financial
"Paid-in-kind dividend on Series C convertible preferred stock | | | (2,000"
Total revenue $47.8M +16% YoY
Life Sciences Services revenue $26.9M +18% YoY
Life Sciences Products revenue $20.9M +15% YoY
Net loss $10.5M narrowed vs $12.0M prior year
Adjusted EBITDA from continuing ops -$0.6M improved from -$2.8M prior year
Guidance

Full-year 2026 revenue guidance raised to $192–$196M.

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, DC 20549

  

FORM 8-K

 

CURRENT REPORT

 Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934

 

Date of Report (Date of earliest event reported): May 4, 2026

 

CRYOPORT, INC. 

(Exact name of registrant as specified in its charter)

 

Nevada   001-34632   88-0313393
(State or other jurisdiction
of incorporation)
  (Commission File Number)   (IRS Employer
Identification No.)
         

112 Westwood Place, Suite 350Brentwood, TN 37027

(Address of principal executive offices, including zip code)
         
Registrant’s telephone number, including area code: (949) 470-2300
 
Not Applicable
(Former name or former address, if changed since last report)

  

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

 

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
     
¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
     
¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
     
¨ Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
     

Securities registered pursuant to Section 12(b) of the Act:

 

Title of each class   Trading Symbol   Name of each exchange on which
registered
Common Stock, $0.001 par value   CYRX   The NASDAQ Stock Market LLC

 

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter). Emerging growth company ¨

 

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨

 

 

  

 

 

 

Item 2.02Results of Operations and Financial Condition.

 

On May 4, 2026, Cryoport, Inc. (the “Company”) issued a press release announcing its financial results for the first quarter ended March 31, 2026. A copy of the press release issued by the Company is attached hereto as Exhibit 99.1.

 

The information, including the exhibit attached hereto, in this Current Report on Form 8-K shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that Section, nor shall it be deemed incorporated by reference in any filing under the Securities Act of 1933 or the Exchange Act, except as otherwise expressly stated in such filing.

 

Item 9.01. Financial Statements and Exhibits

 

(d) Exhibits. The following material is filed as an exhibit to this Current Report on Form 8-K:

  

Exhibit
Number
 
99.1Press Release dated May 4, 2026 issued by the Company.
  
104Cover Page Interactive Data File (embedded within the inline XBRL document)

 

 

 

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

Date: May 4, 2026 Cryoport, Inc.
   
  /s/ Robert Stefanovich
  Robert Stefanovich
  Chief Financial Officer

 

 

 

 

Exhibit 99.1

 

 

Cryoport Reports First Quarter 2026 Financial Results

 

First quarter revenue grew 16% year-over-year to $47.8 million

 

Commercial cell and gene therapy (CGT) revenue grew 26% year-over-year to $9.1 million, reflecting continued expansion in approved CGT programs

 

Life Sciences Services revenue increased 18% year-over-year, led by 21% growth in BioStorage/BioServices

 

Life Sciences Products revenue increased 15% year-over-year, driven by strong demand for cryogenic systems

 

Supporting a record 766 global clinical trials and 21 commercially approved CGTs as of March 31, 2026

 

Company raises full-year revenue guidance to $192 million - $196 million

 

NASHVILLE, Tennessee, May 4, 2026, - Cryoport, Inc. (NASDAQ: CYRX) (“Cryoport” or the “Company”), a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, today announced financial results for its first quarter (Q1) of 2026.

 

Jerrell Shelton, CEO of Cryoport, commented, “Cryoport delivered a strong start to 2026 with first-quarter revenue of $47.8 million, up 16% year-over-year, reflecting a continuation of our momentum over the past several quarters across our integrated services and products platform. Revenue in support of commercial Cell and Gene Therapies (CGT) grew 26% to $9.1 million, while clinical trial support revenue grew 18% to $12.9 million. We continue to support one of the industry’s broadest CGT pipelines, and our leadership across both clinical and commercial programs positions us well for sustainable growth.

 

“Our Life Sciences Services segment delivered another strong quarter, with revenue increasing 18% year-over-year, including 21% growth in BioStorage/BioServices. This performance reflects the increasing scope and complexity of the Cell & Gene Therapy programs we support and underscores the critical role we play in supporting our clients with our integrated, temperature-controlled supply chain services.

 

“Our Life Sciences Products segment also performed very well, generating 15% revenue growth, driven by global demand for MVE Biological Solutions’ cryogenic systems. MVE continues to innovate and further solidify its position as the global leader in high-quality cryogenic systems.

 

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“This growth across both our reporting segments, combined with solid gross margins and continued operational discipline, drove a $2.2 million year-over-year improvement in adjusted EBITDA from continuing operations, advancing us meaningfully along our “pathway to profitability.”

 

“Looking ahead, we see multiple growth catalysts extending beyond 2026, including the planned launch of BioServices operations at our Global Supply Chain Center in Paris, France in the third quarter, and the planned opening of our new Global Supply Chain Center in Santa Ana, California in the fourth quarter. These strategic investments expand our global footprint in key geographies and further strengthen our ability to support the advancement and commercialization of life-saving therapies globally. Reflecting on our strong performance in the first quarter and increased visibility into the remainder of the year, we are raising our full-year revenue guidance to $192 million to $196 million,” concluded Mr. Shelton.

 

The following table presents Q1 2026 revenue compared with Q1 2025:

 

Cryoport, Inc. and Subsidiaries

Revenue       

 

   Three Months Ended
March 31,
(unaudited)
 
(in thousands)  2026   2025   % Change 
Life Sciences Services  $26,898   $22,865    18%
BioLogistics Solutions   21,668    18,531    17%
BioStorage/BioServices   5,230    4,334    21%
Life Sciences Products  $20,900   $18,175    15%
Total Revenue  $47,798   $41,040    16%

 

BioLogistics Solutions revenue increased 17% year-over-year in Q1 2026, driven by increasing customer activity, continued commercial product maturation, and clinical advancement within the CGT market. BioStorage/BioServices revenue grew 21% year-over-year, reflecting strong demand for our expanded, integrated services offering, which provides seamless, secure handling of temperature-sensitive materials across our global network.

 

Revenue from the support of commercial CGTs increased 26% year-over-year to $9.1 million and as of March 31, 2026, the number of commercial therapies we support increased to 21.

 

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As of March 31, 2026, Cryoport supported a total of 766 global clinical trials, a net increase of 55 clinical trials over March 31, 2025, with 91 of these clinical trials in Phase 3. The number of trials by phase and region are as follows:

 

Cryoport Supported Clinical Trials by Phase

 

   March 31, 
Clinical Trials  2024   2025   2026 
Phase 1   286    304    318 
Phase 2   312    328    357 
Phase 3   77    79    91 
Total   675    711    766 

 

Cryoport Supported Clinical Trials by Region  

 

   March 31, 
Clinical Trials  2024   2025   2026 
Americas   518    544    569 
EMEA   112    118    143 
APAC   45    49    54 
Total   675    711    766 

 

In Q1 2026, four Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred. During the first quarter, Cryoport’s customer, Rocket Pharmaceuticals, received U.S. Food and Drug Administration (FDA) accelerated approval for their gene therapy KRESLADI™ for the treatment of pediatric patients with severe leukocyte adhesion deficiency-I (LAD-I). Severe LAD-I is an ultra-rare, life-threatening pediatric genetic immunodeficiency characterized by recurrent infections and high early-childhood mortality without treatment. For the balance of 2026, we anticipate another 10 possible BLA/MAA application filings and 8 additional new therapy approvals.

 

Operational milestones

 

Life Sciences Services

 

BioServices launch at our Global Supply Chain Center in Paris, France, expected in Q3, 2026.

 

Continued progress toward the launch of our state-of-the-art Global Supply Chain Center in Santa Ana, California, expected in Q4, 2026.

 

First cryopreserved clinical trial patient materials shipped in Q1 for two of our clients at our IntegriCell® facilities in Belgium and the U.S.

 

Cryoport Systems named Best Logistics & Supply Chain Management Supplier - Digital Technology & Software at the 2026 Asia Pacific Biopharma Excellence Awards in Singapore.

 

Life Sciences Products

 

MVE Biological Solutions (MVE) introduced its new Fusion® 800 Series, the next evolution of MVE’s patented, award-winning Fusion technology, a self-sustaining cryogenic freezer that eliminates the need for a continuous liquid nitrogen (LN₂) supply feed, delivering exceptional reliability, safety, and sustainability in a compact footprint designed for space-constrained environments.

 

Release of MVE HE (High Efficiency) cryogenic storage systems series integrated with the new MVE CryoVerse™ Connect Controller platform.

 

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Financial Highlights

 

On June 11, 2025, the Company completed the divestiture of its CRYOPDP specialty courier business to DHL Group as part of a strategic partnership. The results of CRYOPDP, a former business within Cryoport’s Life Sciences Services segment, are presented as discontinued operations for all periods and are excluded from the non-GAAP financial measures in this release.

 

Revenue

 

Total revenue for Q1 2026 was $47.8 million, compared to $41.0 million for Q1 2025, a year-over-year increase of 16%, or $6.8 million.

 

oLife Sciences Services revenue for Q1 2026 (representing 56% of our total revenue) was $26.9 million, compared to $22.9 million for Q1 2025, up 18% year-over-year, including BioStorage/BioServices revenue of $5.2 million, up 21% year-over-year.

 

oLife Sciences Products revenue for Q1 2026 (representing 44% of our total revenue) was $20.9 million, compared to $18.2 million for Q1 2025, up 15% year-over-year.

 

Gross Margin

 

Total gross margin was 45.8% for Q1 2026, compared to 45.4% for Q1 2025.

 

oGross margin for Life Sciences Services was 48.9% for Q1 2026, compared to 47.9% for Q1 2025.

 

oGross margin for Life Sciences Products was 41.9% for Q1 2026, compared to 42.3% for Q1 2025.

 

Operating Costs and Expenses

 

Operating costs and expenses were $31.5 million for Q1 2026, compared to $25.8 million for Q1 2025.

 

Loss from Continuing Operations

 

Loss from continuing operations was $9.4 million for Q1 2026, compared to a loss of $6.7 million for Q1 2025.

 

Net Loss – including Discontinued Operations

 

Net loss was $10.5 million for Q1 2026, compared to net loss of $12.0 million for Q1 2025.

 

Net loss attributable to common stockholders for Q1 2026 was $12.5 million, or $0.25 per share, compared to net loss attributable to common stockholders of $14.0 million, or $0.28 per share for Q1 2025.

 

Adjusted EBITDA from Continuing Operations

 

Adjusted EBITDA from continuing operations was a negative $0.6 million for Q1 2026, compared to a negative $2.8 million for Q1 2025.

 

Cash, Cash equivalents, and Short-Term Investments

 

Cryoport held $403.6 million in cash, cash equivalents, and short-term investments as of March 31, 2026.

 

Note: All reconciliations of GAAP to adjusted (non-GAAP) figures above are detailed in the reconciliation tables included later in the press release.

 

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Additional Information

 

Further information on Cryoport’s financial results is included in the attached condensed consolidated balance sheets and statements of operations, and additional explanations of Cryoport’s financial performance are provided in the Company’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2026, which is expected to be filed with the SEC on May 4, 2026. Additionally, the full report will be available in the SEC Filings section of the Investor Relations section of Cryoport’s website at www.cryoportinc.com.

 

Earnings Conference Call Information

 

IMPORTANT INFORMATION: In addition to the earnings release, a document titled “Cryoport First Quarter 2026 in Review”, providing a review of Cryoport’s business update, will be issued at 4:05 p.m. ET on Monday, May 4, 2026. The document is designed to be read in advance of the questions and answers conference call and will be accessible at https://ir.cryoportinc.com/news-events/ir-calendar.

 

Cryoport management will host a conference call at 5:00 p.m. ET on May 4, 2026. The conference call will be in the format of a questions and answers session and will address any queries investors have regarding the Company’s reported results. A slide deck will accompany the call.

 

Conference Call Information

 

Date: Monday, May 4, 2026
Time: 5:00 p.m. ET
Dial-in numbers: 1-800-717-1738 (U.S.), 1-646-307-1865 (International)
Confirmation code: Request the “Cryoport Call” or Conference ID: 1191652
Live webcast:

‘Investor Relations’ section at www.cryoportinc.com or click here.

 

Please allow 10 minutes prior to the call to visit this site to download and install any necessary audio software.

 

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The questions and answers call will be recorded and available approximately three hours after completion of the live event in the Investor Relations section of the Company's website at www.cryoportinc.com for a limited time. To access the replay of the questions and answers click here. A dial-in replay of the call will also be available to those interested, until May 11, 2026. To access the replay, dial 1-844-512-2921 (United States) or 1-412-317-6671 (International) and enter replay entry code: 1191652#.

 

About Cryoport, Inc.

 

Cryoport, Inc. (Nasdaq: CYRX) is a leading global provider of integrated temperature-controlled supply chain solutions for the life sciences, with an emphasis on regenerative medicine. We support biopharmaceutical companies, contract manufacturers (CDMOs), contract research organizations (CROs), developers, and researchers with a comprehensive suite of services and products designed to minimize risk and maximize reliability across the temperature-controlled supply chain for the life sciences. Our integrated supply chain platform includes the Cryoportal® Logistics Management Platform, advanced temperature-controlled packaging, informatics, specialized biologistics, biostorage, bioservices, cryopreservation services, and cryogenic systems, which in varying combinations deliver end-to-end solutions that meet the rigorous demands of the life sciences. With innovation, regulatory compliance, and agility at our core, we are "Enabling the Future of Medicine™."

 

Headquartered in Nashville, Tennessee, our company maintains a strong global presence with operations across the Americas, EMEA, and APAC.

 

For more information, visit www.cryoportinc.com or follow via LinkedIn at https://www.linkedin.com/company/cryoportinc or @cryoport on X, formerly known as Twitter at https://x.com/cryoport for live updates.

 

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Forward-Looking Statements

 

Statements in this press release which are not purely historical, including statements regarding the Company's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, those related to the Company's industry, business, long-term growth prospects, plans, strategies, acquisitions, future financial results and financial condition, such as the Company's outlook and guidance for full-year 2026 revenue and the related assumptions and factors expected to drive revenue, projected growth trends in the markets in which the Company operates, the Company's plans and expectations regarding the launch of new products and services, such as the expected timing and benefits of such products and services launches, the Company’s expectations about future benefits of its acquisitions, and anticipated regulatory filings, approvals, label/geographic expansions or moves to earlier lines of treatment approved with respect to the products of the Company's clients. Forward-looking statements also include those related to the Company’s expectations about future benefits relating to the CRYOPDP divestiture and strategic partnership with DHL (collectively, the “DHL Transaction”), the Company’s plans regarding its Global Supply Chain Centers, including expected timing of future openings, the Company’s plans and expectations relating to its strategic pivot to expand its global partnerships, and the Company’s expectation of revenue contribution from IntegriCell’s cryopreservation service centers throughout 2026. It is important to note that the Company's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effects of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, tariffs and other trade restrictions, foreign currency fluctuations, trends in the products markets, any U.S federal government shutdown, variations in the Company's cash flow, market acceptance risks, and technical development risks. Additional risks and uncertainties relating to the DHL Transaction include, but are not limited to, the risk that any disruption resulting from the DHL Transaction may adversely affect our businesses and business relationships, including with employees and suppliers. The Company's business could be affected by other factors discussed in the Company's SEC reports, including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. The forward-looking statements contained in this press release speak only as of the date hereof and the Company cautions investors not to place undue reliance on these forward-looking statements. Except as required by law, the Company disclaims any obligation and does not undertake to update or revise any forward-looking statements in this press release.

 

Cryoport Investor Contacts:

Todd Fromer / Scott Eckstein

KCSA Strategic Communications

cryoport@kcsa.com

 

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Cryoport, Inc. and Subsidiaries

Condensed Consolidated Statements of Operations    

 

   Three Months Ended
March 31,
(unaudited)
 
(in thousands, except share and per share data)  2026   2025 
Revenue        
Life Sciences Services revenue  $26,898   $22,865 
Life Sciences Products revenue   20,900    18,175 
Total revenue   47,798    41,040 
Cost of revenue:          
Cost of services revenue   13,747    11,920 
Cost of products revenue   12,138    10,479 
Total cost of revenue   25,885    22,399 
Gross margin   21,913    18,641 
Operating costs and expenses:          
Selling, general and administrative   27,620    21,901 
Engineering and development   3,907    3,934 
Total operating costs and expenses:   31,527    25,835 
Loss from operations   (9,614)   (7,194)
Other income (expense):          
Investment income   3,090    1,573 
Interest expense   (432)   (583)
Other expense, net   (2,368)   (300)
Loss before provision for income taxes   (9,324)   (6,504)
Provision for income taxes   (108)   (234)
Loss from continuing operations  $(9,432)  $(6,738)
Loss from discontinued operations, net   (1,112)   (5,243)
Net loss  $(10,544)  $(11,981)
Paid-in-kind dividend on Series C convertible preferred stock   (2,000)   (2,000)
Net loss attributable to common stockholders  $(12,544)  $(13,981)
Net loss per share attributable to common stockholders - basic and diluted  $(0.25)  $(0.28)
Weighted average common shares issued and outstanding - basic and diluted   49,897,817    49,947,012 

 

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Cryoport, Inc. and Subsidiaries

Condensed Consolidated Balance Sheets    

 

   March 31,   December 31, 
   2026   2025 
(in thousands)  (unaudited)     
Current assets          
Cash and cash equivalents  $272,912   $250,494 
Short-term investments   130,722    160,714 
Accounts receivable, net   39,004    33,359 
Inventories   21,750    23,188 
Prepaid expenses and other current assets   6,147    8,419 
Total current assets   470,535    476,174 
Property and equipment, net   89,805    85,448 
Operating lease right-of-use assets   39,299    39,720 
Intangible assets, net   138,721    138,082 
Goodwill   22,137    22,400 
Deposits   2,046    2,092 
Deferred tax assets   1,066    1,073 
Total assets  $763,609   $764,989 
           
Current liabilities          
Accounts payable and other accrued expenses  $15,937   $15,283 
Accrued compensation and related expenses   17,007    12,980 
Deferred revenue   2,314    943 
Current portion of operating lease liabilities   3,641    4,133 
Current portion of finance lease liabilities   419    422 
Current portion of convertible senior notes, net   185,390    185,094 
Current portion of notes payable   159    163 
Total current liabilities   224,867    219,018 
Notes payable, net   1,027    1,087 
Operating lease liabilities, net   39,173    39,078 
Finance lease liabilities, net   680    741 
Deferred tax liabilities   1,580    1,354 
Other long-term liabilities   663    444 
Contingent consideration   630    629 
Total liabilities   268,620    262,351 
Total stockholders' equity   494,989    502,638 
Total liabilities and stockholders' equity  $763,609   $764,989 

 

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Note Regarding Use of Non-GAAP Financial Measures

 

To supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measure of financial performance as defined in Regulation G of the Securities Exchange Act of 1934 is included in this release: adjusted EBITDA from continuing operations. Non-GAAP financial measures are not calculated in accordance with GAAP, are not based on any comprehensive set of accounting rules or principles and may be different from non-GAAP financial measures presented by other companies. Non-GAAP financial measures, including adjusted EBITDA from continuing operations, should not be considered as a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP.

 

Adjusted EBITDA from continuing operations is defined as loss from continuing operations adjusted for net interest expense, income taxes, depreciation and amortization expense, stock-based compensation expense, acquisition and integration costs, cost reduction initiatives, investment income, unrealized loss on investments, foreign currency loss, changes in fair value of contingent consideration and charges or gains resulting from non-recurring events, as applicable.

 

Management believes that adjusted EBITDA from continuing operations provides a useful measure of Cryoport's operating results, a meaningful comparison with historical results and with the results of other companies, and insight into Cryoport's ongoing operating performance. Further, management and the Company’s board of directors utilize adjusted EBITDA from continuing operations to gain a better understanding of Cryoport's comparative operating performance from period to period and as a basis for planning and forecasting future periods. Adjusted EBITDA from continuing operations is also a significant performance measure used by Cryoport in connection with its incentive compensation programs. Management believes adjusted EBITDA from continuing operations, when read in conjunction with Cryoport's GAAP financials, is useful to investors because it provides a basis for meaningful period-to-period comparisons of Cryoport's ongoing operating results, including results of operations, against investor and analyst financial models, helps identify trends in Cryoport's underlying business and in performing related trend analyses, and it provides a better understanding of how management plans and measures Cryoport's underlying business.

 

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Cryoport, Inc. and Subsidiaries

Reconciliation of GAAP loss from continuing operations to adjusted EBITDA

(unaudited)    

 

   Three Months Ended
March 31,
 
(in thousands)  2026   2025 
GAAP loss from continuing operations  $(9,432)  $(6,738)
Non-GAAP adjustments to loss:          
Depreciation and amortization expense   6,402    6,134 
Acquisition and integration costs       1 
Cost reduction initiatives       216 
Investment income   (3,090)   (1,573)
Unrealized loss on investments   2,105    193 
Foreign currency loss   454    245 
Interest expense, net   432    583 
Stock-based compensation expense   2,395    3,064 
Change in fair value of contingent consideration   15    (5,178)
Income taxes   108    234 
Adjusted EBITDA from continuing operations  $(611)  $(2,819)

 

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FAQ

How did Cryoport (CYRX) perform financially in Q1 2026?

Cryoport reported Q1 2026 revenue of $47.8 million, up 16% year-over-year. Life Sciences Services contributed $26.9 million and Life Sciences Products $20.9 million. Despite growth, the company recorded a net loss of $10.5 million, or -$0.25 per share.

How fast is Cryoport’s cell and gene therapy business growing?

Revenue supporting commercial cell and gene therapies grew 26% year-over-year to $9.1 million in Q1 2026. Clinical trial support revenue rose 18% to $12.9 million. Cryoport now supports 766 global clinical trials, including 91 Phase 3 studies, reflecting expanding exposure to advanced therapies.

What profitability metrics did Cryoport (CYRX) report for Q1 2026?

Cryoport posted a loss from continuing operations of $9.4 million and a net loss of $10.5 million in Q1 2026. However, adjusted EBITDA from continuing operations improved to -$0.6 million, compared with -$2.8 million a year earlier, showing progress toward its profitability objectives.

What is Cryoport’s 2026 revenue guidance after Q1 results?

Reflecting Q1 performance and greater visibility, Cryoport raised its full-year 2026 revenue guidance to $192 million to $196 million. This updated outlook is based on continued segment growth, expanding global supply chain centers, and ongoing demand across cell and gene therapy programs.

What is Cryoport’s liquidity and debt position as of March 31, 2026?

As of March 31, 2026, Cryoport held $272.9 million in cash and cash equivalents and $130.7 million in short-term investments. Current liabilities included $185.4 million of convertible senior notes, contributing to total liabilities of $268.6 million and stockholders’ equity of $495.0 million.

How many clinical trials and commercial therapies does Cryoport support?

As of March 31, 2026, Cryoport supported 766 global clinical trials, up from prior years, with 91 in Phase 3. The company also supported 21 commercial therapies. This broad footprint spans the Americas, EMEA, and APAC, anchoring its role in regenerative medicine supply chains.

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