Welcome to our dedicated page for Editas Medicine SEC filings (Ticker: EDIT), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Editas Medicine, Inc. (Nasdaq: EDIT) SEC filings page on Stock Titan provides access to the company’s regulatory disclosures filed with the U.S. Securities and Exchange Commission. As a clinical-stage gene editing company focused on in vivo CRISPR/Cas12a and CRISPR/Cas9 medicines, Editas uses current reports on Form 8-K and other periodic filings to communicate material events, program updates, collaborations, and financial results to investors.
Through its 8-K filings, Editas Medicine furnishes press releases announcing quarterly financial results, cash runway expectations, and business highlights. These documents describe research and development expenses, collaboration and other research revenues, restructuring and impairment charges, and the company’s view of its ability to fund operating expenses and capital expenditure requirements over a multi-year period. They also outline key risk considerations and refer readers to the company’s Annual Report on Form 10-K and subsequent filings for detailed risk factors.
Filings also summarize important scientific and pipeline milestones. For example, Editas has used 8-K reports to describe the nomination of EDIT-401 as its lead in vivo development candidate for hyperlipidemia, preclinical proof-of-concept data demonstrating approximately 90% LDL-C reduction in non-human primates and mice, and the therapeutic strategy of using CRISPR/Cas9 with dual guide RNAs and lipid nanoparticle delivery to upregulate LDLR. Other filings discuss in vivo proof-of-concept data for EDIT-401 presented at major gene and cell therapy conferences.
Investors can review these SEC filings to understand how Editas Medicine reports the status of its in vivo HSC program for sickle cell disease and beta thalassemia, its collaboration with Bristol Myers Squibb on T cell medicines, and payments under its license agreement with Vertex Pharmaceuticals. On Stock Titan, AI-powered tools can help summarize lengthy filings, highlight key sections related to EDIT-401, cash runway, collaborations, and program changes, and make it easier to interpret complex technical and financial disclosures without reading every line of each document.
Editas Medicine reported that it furnished a press release announcing financial results for the fiscal quarter ended September 30, 2025, along with other business highlights.
The press release was provided as Exhibit 99.1 and designated as furnished, not filed. The company’s common stock trades on Nasdaq under the symbol EDIT.
Editas Medicine, Inc. filed a report describing new preclinical data for EDIT-401, an experimental one-time gene-editing therapy designed to significantly reduce LDL-cholesterol by increasing LDL receptor levels. At a major gene and cell therapy congress, the company reported that in non-human primates a single dose of EDIT-401 led to LDL-C reductions equal to or exceeding 90% within 48 hours. Similar LDL-C reductions of at least 90% were also seen in mice with high baseline LDL-C and reduced LDL receptor function, with effects maintained over a three-month study. The therapy uses a CRISPR/Cas9 nuclease with dual guide RNAs delivered via lipid nanoparticles to disrupt negative regulatory elements in the 3’ UTR, which Editas says increased LDL receptor protein in primate liver by at least six-fold while requiring only moderate functional editing of LDLR alleles.
Linda C. Burkly, Executive Vice President and Chief Scientific Officer of Editas Medicine, reported a sale of 710 shares of the issuer's common stock on 09/03/2025 at a price of $2.5961 per share. The filing states the sale was effected under a durable automatic sales instruction plan adopted July 3, 2023, to satisfy tax withholding triggered by restricted stock units that vested on 09/02/2025, and the sale was not a discretionary trade. Following the transaction Burkly beneficially owns 69,490 shares, which includes 5,802 shares acquired under the company Employee Stock Purchase Plan.
Editas Medicine insider sale disclosed on Form 4: Amy Parison, SVP and Chief Financial Officer, reported a transaction dated 09/03/2025 showing the disposition of 458 shares of Editas Medicine common stock at a price of $2.5961 per share. After the sale, Ms. Parison beneficially owned 16,369 shares, held directly. The filing states the sale was effected under a durable automatic sales instruction plan adopted July 7, 2022, to satisfy tax withholding obligations tied to the vesting of restricted stock units on 09/02/2025, and that the sale was not a discretionary trade by the reporting person.
Editas Medicine director and CEO Gilmore O'Neill sold 5,592 shares of Editas Medicine (EDIT) on 09/03/2025 at $2.5961 per share under a pre-existing Rule 10b5-1 automatic sales plan. The filing states the sale was to satisfy tax withholding obligations arising from restricted stock units that vested on 09/02/2025 and was not a discretionary trade. After the transaction the reporting person beneficially owned 274,690 shares.
Editas Medicine used this report to highlight a new in vivo gene-editing candidate, EDIT-401, designed to treat hyperlipidemia by editing the LDLR gene to increase LDL receptor protein and lower LDL cholesterol. In non-human primates, a single dose produced about a 90 percent mean reduction in LDL-C across four dose levels and at least a six-fold mean increase in liver LDLR protein, with no adverse effects reported and transient liver enzyme elevations resolving within one week.
The company plans to prioritize EDIT-401, aiming to submit an IND or CTA by mid-2026 and to achieve in vivo human proof-of-concept data by the end of 2026, while continuing earlier work on hematopoietic stem cell and other cell-type programs. It reaffirmed that existing cash, cash equivalents, marketable securities, and retained portions of payments from its Vertex license are expected to fund operations and capital needs into the second quarter of 2027.
Editas Medicine (EDIT) Form 144 notice reports a proposed sale of 7,000 shares of Common Stock to be executed through ETrade on 09/03/2025 on Nasdaq with an aggregate market value of $19,110.00. The filing shows these shares were acquired on 09/02/2025 through restricted stock unit vesting (equity compensation), with 11,294 shares listed as acquired on that date. The filing also discloses a sale by Gilmore O'Neill of 15,192 shares on 06/03/2025 for gross proceeds of $26,195.57. The notice includes the standard representation that the seller does not possess undisclosed material adverse information about the issuer.
Editas Medicine (EDIT) submitted a Form 144 disclosing a proposed sale of 800 shares of common stock with an aggregate market value of $2,184, listed for sale on Nasdaq and dated approximately 09/03/2025. The securities were acquired on 09/02/2025 through restricted stock unit vesting (1,550 shares acquired) and payment was in the form of equity compensation. The filing also reports two prior sales by the same person in the past three months: 726 shares on 06/03/2025 ($1,251.84) and 5,121 shares on 07/31/2025 ($12,756.92). The form includes the standard attestation that the seller is unaware of undisclosed material adverse information.
Editas Medicine (EDIT) reported a net loss of $129.3 million for the six months ended June 30, 2025, or $1.54 per share, widening its accumulated deficit to $1.6 billion. Total assets fell to $210.6 million from $341.6 million at year-end 2024, and stockholders' equity declined to $19.2 million. Cash and cash equivalents were $138.5 million and marketable securities were $39.9 million, totaling $178.5 million in liquid investments.
The company discontinued its ex vivo reni-cel program and initiated a workforce reduction of approximately 180 positions (about 65%), recording $66.9 million of restructuring and impairment charges in the six months and $79.2 million since the December 2024 decision. Editas received $57.0 million from DRI under a sale-of-future-revenues agreement (accounted for as debt; estimated effective interest rate 15.1%, liability $56.7 million) and has an amended ATM facility with $141.4 million remaining capacity after $8.6 million of sales. Management expects existing cash, cash equivalents and marketable securities to fund operations for at least twelve months from the consolidated financial statement issuance date.
Editas Medicine announced that it has furnished a press release reporting its financial results for the fiscal quarter ended June 30, 2025 and other business highlights. The press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and is expressly furnished, not filed, so the numerical results and business detail are contained in that exhibit rather than in the body of the filing.