Freenome (FRNM) posts $132.6M loss but raises $295.5M via SPAC and PIPE

Rhea-AI Filing Summary

Freenome, Inc. files an amendment to provide full interim financials and MD&A for Freenome Holdings, Inc. ahead of and around its July 20, 2026 business combination with Perceptive Capital Solutions Corp., which was accounted for as a reverse recapitalization.

For the six months ended June 30, 2026, Freenome generated $6.5 million in revenue, primarily from a major collaboration with Exact Sciences plus U.K. test sales, versus $1.5 million a year earlier. Net loss widened to $132.6 million, with $97.1 million of cash used in operating activities, reflecting heavy R&D and G&A spending.

At June 30, 2026 Freenome reported total assets of $398.5 million, including cash, cash equivalents and short-term marketable securities of about $102.0 million, deferred revenue of $71.1 million tied mainly to the Exact Sciences license, and significant lease and cloud-service commitments. Management states that existing liquidity plus $295.5 million in net proceeds from the SPAC/PIPE transaction is expected to fund operations for at least 12 months from issuance.

Positive

• $6.5 million in first-half 2026 revenue, up sharply from $1.5 million a year earlier, driven by the Exact Sciences collaboration and U.K. test sales.
• Closing of the SPAC merger and related PIPE provided $295.5 million in net cash proceeds, materially strengthening the balance sheet.
• Management expects existing cash plus short-term securities of about $102.0 million and SPAC/PIPE proceeds to fund operations for at least the next 12 months.

Negative

• Net loss increased to $132.6 million for the first half of 2026, compared with $116.6 million in the prior-year period.
• Operating activities used $97.1 million of cash in the first half of 2026, indicating a high burn rate relative to current revenue.
• Accumulated deficit reached approximately $1.5 billion, highlighting the company’s long history of losses.

Filing Explained

The amendment documents completed share conversions and adds pro forma reporting; it does not announce a new transaction or post-closing development.

This Form 8-K/A adds Freenome’s unaudited June 30 financial statements, MD&A, and pro forma information to the earlier material-event report; it is a reporting supplement rather than a new closing.

The July 20 business combination had already closed, converting Freenome’s legacy common and preferred shares into 68,065,429 shares of New Freenome common stock, and the filing states that the transaction was accounted for as a reverse recapitalization, with Freenome as the accounting acquirer.

At closing, Roche’s $75.0 million principal and $2.5 million of accrued interest converted into 6,460,616 New Freenome shares.

The closing also included a $240.0 million PIPE within $310.7 million of gross proceeds; a PIPE is a private securities sale to selected investors.

The amendment expressly says it does not amend the other original-report items or update developments after the original filing date, so its added information relates to the completed July 20 transaction and the June 30 reporting period.

8-K Event Classification

2 items: 2.01, 9.01

2 items

Item 2.01 Completion of Acquisition or Disposition of Assets Financial

The company completed a significant acquisition or sale of business assets.

Item 9.01 Financial Statements and Exhibits Exhibits

Financial statements, pro forma financial information, and exhibit attachments filed with this report.

Key Figures

Revenue H1 2026: $6.496 million Net loss H1 2026: $132.588 million Operating cash used: $97.110 million +5 more

8 metrics

Revenue H1 2026 $6.496 million Total revenue for the six months ended June 30, 2026

Net loss H1 2026 $132.588 million Net loss for the six months ended June 30, 2026

Operating cash used $97.110 million Net cash used in operating activities for the six months ended June 30, 2026

Cash & short-term securities $102.0 million Cash, cash equivalents and short-term marketable securities as of June 30, 2026

Deferred revenue $71.106 million Current deferred revenue balance as of June 30, 2026

SPAC/PIPE net proceeds $295.5 million Net cash received from business combination and PIPE financing at closing

Total lease liabilities $204.230 million Present value of operating lease obligations as of June 30, 2026

Cloud services commitment $119.1 million Noncancellable cloud computing commitment through January 31, 2029

Key Terms

reverse recapitalization, PIPE financing, deferred revenue, redeemable convertible preferred stock, +2 more

6 terms

reverse recapitalization financial

"The Business Combination was accounted for as a reverse recapitalization"

A reverse recapitalization is a way for a privately held company to become publicly traded by taking control of an existing public company and swapping ownership rather than going through a traditional public offering. For investors it matters because it can quickly change who controls a company and reshape its share structure and value — like a homeowner swapping houses and keys rather than building a new one — so it can create sudden shifts in stock supply, dilution and market expectations.

PIPE financing financial

"including $240.0 million of gross proceeds from a private investment in public equity ("PIPE")"

Pipe financing is a way for companies to raise money quickly by selling new shares or bonds directly to investors, often before their stock is publicly traded or in the early stages of a project. It’s similar to a company securing a loan from investors, providing quick capital needed for growth or operations. For investors, it can offer opportunities for early involvement and potentially higher returns, but it may also carry increased risk due to the immediate nature of the deal.

deferred revenue financial

"Balance at June 30, 2026 was $71.1 million in deferred revenue"

Cash a company has already received for goods or services it has promised but not yet delivered; it's recorded as a liability because the company still owes that product, service, or future revenue recognition. For investors, deferred revenue signals upcoming work or deliveries that will convert into reported sales over time and affects short-term obligations, cash flow quality, and how quickly a firm can grow recognized revenue—think of it like prepaid subscriptions or gift cards a business must honor later.

redeemable convertible preferred stock financial

"Redeemable convertible preferred stock, $0.0001 par value – 213,700,719 shares authorized"

A redeemable convertible preferred stock is a special class of company shares that combines three features: it pays priority dividends like a safer, higher-ranking share; it can be converted into regular common shares so holders can join in upside; and it can be redeemed, meaning the company can buy it back for cash. For investors this matters because it offers a mix of downside protection and potential upside, but can change ownership stakes (dilution) and cash obligations depending on whether it’s converted or redeemed.

fair value option financial

"The Company elected the fair value option to account for the Exact Convertible Note"

An accounting election that lets a company measure eligible financial assets and liabilities at their current market price, recording gains and losses in the income statement as those prices move. For investors it matters because choosing the fair value option makes reported profits and asset values respond immediately to market swings—like revaluing a house to today’s sale price—so it can increase earnings volatility while giving a more up‑to‑date view of value.

Business Combination financial

"On July 20, 2026, the Company completed the transactions contemplated by the Business Combination Agreement"

A business combination happens when two or more companies join together to operate as one, like two friends merging their teams into a single group. This is important because it can change how companies grow, compete, and make money, often making them bigger and more powerful in the market.

FAQ

How much revenue did Freenome (FRNM) report for the first half of 2026?

Freenome reported $6.5 million in revenue for the six months ended June 30, 2026, mainly from its Exact Sciences collaboration and U.K. EarlyCDT Lung products, up from $1.5 million in the same period of 2025.

What was Freenome (FRNM)’s net loss for the six months ended June 30, 2026?

Freenome recorded a net loss of $132.6 million for the first half of 2026, compared with $116.6 million a year earlier, reflecting substantial research and development and general and administrative expenses.

What is Freenome (FRNM)’s cash position and liquidity outlook as of June 30, 2026?

As of June 30, 2026, Freenome held about $102.0 million in cash, cash equivalents and short-term marketable securities, and later received $295.5 million in net SPAC/PIPE proceeds, which management expects to fund operations for at least 12 months.

How did the SPAC business combination impact Freenome (FRNM)?

On July 20, 2026, Freenome completed a business combination with Perceptive Capital Solutions Corp., treated as a reverse recapitalization. Freenome became a wholly owned subsidiary of New Freenome, and the transaction delivered gross proceeds of about $310.7 million, or $295.5 million net.

What deferred revenue does Freenome (FRNM) report from the Exact Sciences deal?

Freenome reports $71.1 million of deferred revenue at June 30, 2026, largely related to its collaboration and license agreement with Exact Sciences, representing upfront and development funding not yet recognized as revenue.

What are Freenome (FRNM)’s major future commitments?

Freenome discloses a noncancellable cloud services agreement totaling $119.1 million through January 2029 and operating lease obligations with undiscounted payments of $319.9 million, primarily for its Brisbane, California headquarters and lab facilities.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 08/13/2026 - 05:29 PM Accepted by SEC EDGAR 08/13/2026 - 05:28 PM Learn about SEC filing dates

false000201752600020175262026-07-202026-07-20

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K/A

Amendment No. 1

CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): August 13, 2026 (July 20, 2026)

FREENOME, INC.

(Exact name of registrant as specified in its charter)

Delaware		001-42126		98-1783595
(State or other jurisdiction of incorporation)		(Commission File Number)		(IRS Employer Identification No.)

Genesis Marina, 3300 Marina Blvd,

Brisbane, CA 94005

(Address of principal executive offices including zip code)

Registrant’s telephone number, including area code: (650) 446-6630

Not Applicable

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

☐
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

☐
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

☐
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

☐
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Securities registered pursuant to Section 12(b) of the Act:

Title of each class		Trading Symbol		Name of each exchange on which registered
FRNM		Common Stock, par value $0.0001 per share		NASDAQ

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

Emerging growth company ☒

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

INTRODUCTORY NOTE

On July 20, 2026, Freenome, Inc. (“New Freenome,” and previously known as Perceptive Capital Solutions Corp, a Cayman Islands exempted company (“PCSC”)), consummated the previously announced business combination (the “Business Combination”) pursuant to the terms of the business combination agreement, dated December 5, 2025 and amended on July 20, 2026, with StarNet Merger Sub I, Corp., a Delaware corporation and wholly-owned subsidiary of PCSC, StarNet Merger Sub II, LLC, a Delaware limited liability company and wholly-owned subsidiary of PCSC, and Freenome Holdings, Inc., a Delaware corporation (“Freenome”).

New Freenome filed a Current Report on Form 8-K in connection with the Business Combination on July 24, 2026 (the “Original Report”). New Freenome is filing this Current Report on Form 8-K/A (“Amendment No. 1”) in order to include:

(a) The unaudited condensed consolidated financial statements of Freenome as of June 30, 2026 and for the three and six months ended June 30, 2026 and 2025 as Exhibit 99.1;

(b) Management’s Discussion and Analysis of Financial Condition and Results of Operations of Freenome for the three and six months ended June 30, 2026 and 2025 as Exhibit 99.2; and

(c) The unaudited pro forma condensed combined financial information of New Freenome as of and for the six months ended June 30, 2026 and the year ended December 31, 2025 as Exhibit 99.3.

This Amendment No. 1 does not amend any other item of the Original Report or purport to provide an update or a discussion of any developments at New Freenome or its subsidiaries subsequent to the filing date of the Original Report. Except as provided herein, the disclosures made in the Original Report remain unchanged.

Item 2.01. Completion of Acquisition or Disposition of Assets

Financial Information

Management’s Discussion and Analysis of Financial Condition and Results of Operations of Freenome for the three and six months ended June 30, 2026 and 2025 is set forth in Exhibit 99.2 to this Amendment No. 1, and is incorporated herein by reference.

Quantitative and Qualitative Disclosures about Market Risk

As a “smaller reporting company,” New Freenome is not required to provide this information.

Financial Statements, Supplementary Data and Exhibits

Reference is made to the information set forth in sections (a) and (b) of Item 9.01 of this Amendment No. 1 and is incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits

(a) Financial statements of businesses acquired.

The unaudited condensed consolidated financial statements of Freenome as of and for the six months ended June 30, 2026 and 2025, and the related notes thereto, are set forth in Exhibit 99.1 and are incorporated herein by reference. Also included as Exhibit 99.2 and incorporated herein by reference is Management’s Discussion and Analysis of Financial Condition and Results of Operations of Freenome for the three and six months ended June 30, 2026 and 2025.

(b) Pro Forma financial information.

The unaudited pro forma condensed combined financial information of New Freenome as of and for the six months ended June 30, 2026 and for the year ended December 31, 2025, is set forth in Exhibit 99.3 hereto and is incorporated herein by reference.

(c) Exhibits

Exhibit No.	Description
99.1*	Unaudited condensed consolidated financial statements of Freenome as of June 30, 2026 and for the six months ended June 30, 2026 and 2025.
99.2*	Management’s Discussion and Analysis of Financial Condition and Results of Operations of Freenome for the three and six months ended June 30, 2026 and 2025.
99.3*	Unaudited pro forma condensed combined financial information of New Freenome as of and for the six months ended June 30, 2026 and for the year ended December 31, 2025.
104	Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)

* Filed Herewith.

SIGNATURE

Pursuant to the requirements of the Exchange Act, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	FREENOME, INC.
	By:	/s/ Aaron Elliott
	Name:	Aaron Elliott
	Title:	Chief Executive Officer
Date: August 13, 2026

Exhibit 99.1

FREENOME HOLDINGS, INC.

Condensed Consolidated Balance Sheets (unaudited)

(in thousands, except shares and par value data)

		June 30, 2026				December 31, 2025
Assets
Current assets:
Cash and cash equivalents		$	85,467			$	78,558
Marketable securities			16,557				138,106
Accounts and other receivables			3,547				1,307
Prepaid expenses and other current assets			7,695				8,520
Total current assets			113,266				226,491
Property and equipment, net			156,961				155,776
Operating lease right-of-use assets, net			95,806				97,055
Intangible assets, net			2,758				3,300
Goodwill			10,513				10,513
Other long-term assets			9,635				4,800
Restricted cash			9,560				9,118
Total assets		$	398,499			$	507,053
Liabilities, Convertible Preferred Stock, and Stockholders’ Deficit
Current liabilities:
Accounts payable		$	12,852			$	6,084
Accrued compensation and other related benefits			8,991				13,424
Accrued expenses and other current liabilities			3,390				3,783
Deferred revenue, current			71,106				7,123
Current portion of lease liabilities			11,194				10,114
Total current liabilities			107,533				40,528
Long-term liabilities:
Lease liabilities, net of current portion			193,036				199,015
Convertible note, at fair value			41,700				41,600
Convertible note, related party			65,523				60,895
Deferred revenue, non-current			—				49,138
Other long-term liabilities			17,318				15,433
Total liabilities			425,110				406,609
Commitments and contingencies (Note 13)
Redeemable convertible preferred stock, $0.0001 par value – 213,700,719 shares authorized; 212,541,832 shares issued and outstanding as of June 30, 2026, and December 31, 2025.			1,363,580				1,363,580
Stockholders’ deficit
Common stock, $0.0001 par value – 302,184,000 shares authorized; 26,267,598 shares issued and outstanding as of June 30, 2026, and December 31, 2025.			3				3
Additional paid-in capital			89,471				83,834
Accumulated other comprehensive gain			28				132
Accumulated deficit			(1,479,693	)			(1,347,105	)
Total stockholders’ deficit			(1,390,191	)			(1,263,136	)
Total liabilities, convertible preferred stock, and stockholders’ deficit		$	398,499			$	507,053

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

1

FREENOME HOLDINGS, INC.

Condensed Consolidated Statements of Operations (unaudited)

(in thousands, except share and per share amounts)

		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
Revenue:
License and collaboration revenue		$	1,465			$	—			$	5,155			$	—
Service and other revenue			809				1,101				1,341				1,495
Total revenue			2,274				1,101				6,496				1,495
Operating costs and expenses:
Cost of services			497				509				937				884
Research and development			54,273				47,057				106,387				94,865
General and administrative			12,711				13,723				26,624				26,008
Total operating costs and expenses			67,481				61,289				133,948				121,757
Loss from operations			(65,207	)			(60,188	)			(127,452	)			(120,262	)
Other income (expense), net:
Interest and investment income, net			1,038				1,514				2,729				3,717
Interest expense			(4,859	)			(1	)			(7,863	)			(3	)
Other (expense), net			(1	)			(56	)			(2	)			(57	)
Net loss		$	(69,029	)		$	(58,731	)		$	(132,588	)		$	(116,605	)
Net loss per share attributable to common stockholders, basic and diluted		$	(2.59	)		$	(2.22	)		$	(4.97	)		$	(4.41	)
Weighted-average shares of common stock outstanding, basic and diluted			26,696,158				26,439,086				26,696,158				26,423,995

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

2

FREENOME HOLDINGS, INC.

Condensed Consolidated Statements of Comprehensive Loss (unaudited)

(in thousands)

		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
Net loss		$	(69,029	)		$	(58,731	)		$	(132,588	)		$	(116,605	)
Other comprehensive income (loss):
Unrealized gain (loss) on available for-sale securities			2				(5	)			(85	)			(87	)
Foreign currency translation adjustments			—				49				(19	)			64
Other comprehensive income (loss)			2				44				(104	)			(23	)
Comprehensive loss		$	(69,027	)		$	(58,687	)		$	(132,692	)		$	(116,628	)

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

3

FREENOME HOLDINGS, INC.

Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders’ Deficit (unaudited)

(in thousands, except share amounts)

		Three Months Ended June 30, 2026
		Convertible Preferred Stock								Common Stock								Additional Paid-in Capital				Accumulated Other Comprehensive Gain				Accumulated Deficit				Total Stockholders’ Deficit
		Shares				Amount				Shares				Amount
Balance as of March 31, 2026			212,541,832			$	1,363,580				26,267,598			$	3			$	86,737			$	26			$	(1,410,664	)		$	(1,323,898	)
Stock-based compensation expense			—				—				—				—				2,734				—				—				2,734
Unrealized gain on available for-sale securities			—				—				—				—				—				2				—				2
Net loss			—				—				—				—				—				—				(69,029	)			(69,029	)
Balance as of June 30, 2026			212,541,832			$	1,363,580				26,267,598			$	3			$	89,471			$	28			$	(1,479,693	)		$	(1,390,191	)

		Three Months Ended June 30, 2025
		Convertible Preferred Stock								Common Stock								Additional Paid-in Capital				Accumulated Other Comprehensive Gain (Loss)				Accumulated Deficit				Total Stockholders’ Deficit
		Shares				Amount				Shares				Amount
Balance as of March 31, 2025			212,541,832			$	1,363,580				25,982,283			$	3			$	74,938			$	35			$	(1,185,636	)		$	(1,110,660	)
Issuance of shares upon exercise of stock options			—				—				59,277				(1	)			83				—				—				82
Stock-based compensation expense			—				—				—				—				2,738				—				—				2,738
Unrealized loss on available for-sale securities			—				—				—				—				—				(5	)			—				(5	)
Foreign currency translation adjustment			—				—				—				—				—				49				—				49
Net loss			—				—				—				—				—				—				(58,731	)			(58,731	)
Balance as of June 30, 2025			212,541,832			$	1,363,580				26,041,560			$	2			$	77,759			$	79			$	(1,244,367	)		$	(1,166,527	)

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements

4

FREENOME HOLDINGS, INC.

Condensed Consolidated Statements of Convertible Preferred Stock and Stockholders’ Deficit (unaudited)

(in thousands, except share amounts)

		Six Months Ended June 30, 2026
		Convertible Preferred Stock								Common Stock								Additional Paid-in Capital				Treasury Stock				Accumulated Other Comprehensive Gain (Loss)				Accumulated Deficit				Total Stockholders’ Deficit
		Shares				Amount				Shares				Amount
Balance as of December 31, 2025			212,541,832			$	1,363,580				26,267,598			$	3			$	83,834			$	—			$	132			$	(1,347,105	)		$	(1,263,136	)
Stock-based compensation expense			—				—				—				—				5,637				—				—				—				5,637
Unrealized loss on available for-sale securities			—				—				—				—				—				—				(85	)			—				(85	)
Foreign currency translation adjustment			—				—				—				—				—				—				(19	)			—				(19	)
Net loss			—				—				—				—				—				—				—				(132,588	)			(132,588	)
Balance as of June 30, 2026			212,541,832			$	1,363,580				26,267,598			$	3			$	89,471			$	—			$	28			$	(1,479,693	)		$	(1,390,191	)

		Six Months Ended June 30, 2025
		Convertible Preferred Stock								Common Stock								Additional Paid-in Capital				Treasury Stock				Accumulated Other Comprehensive Gain (Loss)				Accumulated Deficit				Total Stockholders’ Deficit
		Shares				Amount				Shares				Amount
Balance as of December 31, 2024			212,541,832			$	1,363,580				25,973,713			$	3			$	75,259			$	(2,619	)		$	102			$	(1,127,762	)		$	(1,055,017	)
Retirement of treasury stock			—				—				—				—				(2,619	)			2,619				—				—				—
Issuance of shares upon exercise of stock options			—				—				67,847				(1	)			105				—				—				—				104
Stock-based compensation expense			—				—				—				—				5,014				—				—				—				5,014
Unrealized loss on available for-sale securities			—				—				—				—				—				—				(87	)			—				(87	)
Foreign currency translation adjustment			—				—				—				—				—				—				64				—				64
Net loss			—				—				—				—				—				—				—				(116,605	)			(116,605	)
Balance as of June 30, 2025			212,541,832			$	1,363,580				26,041,560			$	2			$	77,759			$	—			$	79			$	(1,244,367	)		$	(1,166,527	)

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements

5

FREENOME HOLDINGS, INC.

Condensed Consolidated Statements of Cash Flows (unaudited)

(in thousands)

		Six Months Ended June 30,
		2026				2025
Cash flows from operating activities
Net loss		$	(132,588	)		$	(116,605	)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization			12,308				12,014
Noncash lease expense			1,249				3,024
Stock-based compensation expense			5,637				5,014
Net accretion and amortization of investments in marketable securities			(1,689	)			(2,581	)
Non-cash interest expense and amortization of debt issuance costs			6,513				—
Change in fair value of convertible note			100				—
Changes in operating assets and liabilities:
Accounts and other receivables			(2,240	)			319
Prepaid expenses and other current assets			825				(1,231	)
Other long-term assets			—				269
Accounts payable			7,802				(1,886	)
Accrued compensation and other related benefits			(4,433	)			(5,143	)
Accrued expenses and other current liabilities			(540	)			201
Deferred revenue			14,845				—
Operating lease liabilities			(4,899	)			6,959
Net cash used in operating activities			(97,110	)			(99,646	)
Cash flows from investing activities
Purchases of marketable securities			(22,547	)			(67,492	)
Proceeds from maturities of marketable securities			145,700				177,800
Purchases of property and equipment			(12,488	)			(17,564	)
Net cash provided by investing activities			110,665				92,744
Cash flows from financing activities
Payments made on finance leases			—				(135	)
Payment for offering costs			(6,185	)			—
Proceeds from issuance of common stock upon exercise of stock options			—				104
Net cash used in financing activities			(6,185	)			(31	)
Effect of exchange rate changes on cash and cash equivalents and restricted cash			(19	)			64
Net increase (decrease) in cash and cash equivalents			7,351				(6,869	)
Cash, cash equivalents and restricted cash at beginning of period			87,676				76,170
Cash, cash equivalents and restricted cash at end of period		$	95,027			$	69,301
Reconciliation to amounts on the Condensed Consolidated Balance Sheets:
Cash and cash equivalents		$	85,467			$	60,183
Restricted cash			9,560				9,118
Total cash, cash equivalents and restricted cash		$	95,027			$	69,301
Supplemental disclosures of noncash investing and financing activities:
Purchases of property and equipment in accounts payable and accrued expenses		$	463			$	26
Unpaid deferred offering costs included in accounts payable and accrued expenses		$	2,330			$	—

The accompanying notes are an integral part of these unaudited condensed consolidated financial statements.

6

FREENOME HOLDINGS, INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)

Note 1—Organization and Summary of Significant Accounting Policies

Description of Business

Freenome Holdings, Inc. (together with its wholly-owned subsidiaries, the “Company”) is a biotechnology company pioneering an early cancer detection platform. The Company’s initial programs are focused on colorectal cancer with a pipeline of single-cancer and multi-cancer tests under development, including lung, breast, cervical, liver, pancreatic and esophageal cancers.

The Company was incorporated in Delaware in 2016. The Company’s headquarters are located in Brisbane, California.

Basis of Presentation and Principles of Consolidation

The accompanying unaudited interim condensed consolidated financial statements have been prepared in accordance with United States generally accepted accounting principles (‘‘U.S. GAAP’’), pursuant to the rules and regulations of the Securities and Exchange Commission (“SEC”) for reporting interim financial information. Any reference in these notes to applicable accounting guidance is meant to refer to the authoritative U.S. GAAP included in the Accounting Standards Codifications (“ASCs”) and Accounting Standards Updates (“ASUs”) issued by the Financial Accounting Standards Board (“FASB”). The unaudited interim condensed consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries. All intercompany balances and transactions have been eliminated in consolidation.

The condensed consolidated balance sheet as of December 31, 2025, included herein, was derived from the audited consolidated financial statements as of that date. Certain information and footnote disclosures typically included in the Company’s audited consolidated financial statements have been condensed or omitted. The accompanying unaudited interim condensed consolidated financial statements have been prepared on the same basis as the annual consolidated financial statements and reflect all adjustments of a normal and recurring nature that are necessary for the fair presentation of the Company’s financial position, results of operations, and cash flows for the periods presented, but are not necessarily indicative of results to be expected for any future annual or interim period. These unaudited interim condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements and footnotes for the year ended December 31, 2025, included in the proxy statement/prospectus filed with the SEC on June 17, 2026.

Use of Estimates

The preparation of unaudited interim condensed consolidated financial statements in conformity with U.S. GAAP requires the Company’s management to make estimates and assumptions that affect the reported amounts of assets and liabilities as of the date of the unaudited interim condensed consolidated financial statements, the reported amounts of revenue and expenses during the reported periods, and the accompanying notes. The Company bases its estimates and judgments on historical experience and on various other assumptions that the Company believes are reasonable under the circumstances. These estimates are based on management’s knowledge about current events and expectations about actions the Company may undertake in the future. Actual results could differ materially from those estimates.

These judgments, estimates and assumptions made by management include, but are not limited to, the determination of:

● fair value of the Company’s convertible preferred stock;

● fair value of the Company’s common stock;

● impairment assessment of goodwill and intangible assets;

● impairment assessment and recoverability of long-lived assets;

● stock-based compensation expense and related assumptions;

● income tax uncertainties and valuation allowance for deferred tax assets;

● performance obligations within a contract and the determination of standalone selling price (“SSP”) for each performance obligation; and

● the fair value of the convertible notes.

Summary of Significant Accounting Policies

The significant accounting policies used by the Company in its presentation of interim financial results are consistent with those described in Note 2 to the Company’s audited consolidated financial statements for the year ended December 31, 2025, issued on March 30, 2026. During the six months ended June 30, 2026, there were no significant changes in the Company’s significant accounting policies from those disclosed in its consolidated financial statements for the year ended December 31, 2025.

7

Liquidity and Capital Resources

The Company has incurred losses and negative cash flows from operations since its inception. During the six months ended June 30, 2026, the Company incurred a net loss of $132.6 million, used $97.1 million of cash in operations and had an accumulated deficit of $1.5 billion. As of June 30, 2026, the Company had approximately $102.0 million in cash, cash equivalents, and short-term marketable securities. Based on its current operating plan, the Company believes that its cash, cash equivalents, and short-term marketable securities as of June 30, 2026, together with the net proceeds of $295.5 million from the Business Combination with PCSC described in Note 17, will be sufficient to fund its anticipated operating expenses and capital expenditure requirements for at least the next 12 months from the date of issuance of these unaudited interim condensed consolidated financial statements.

The Company expects to incur additional losses in the future and will be required to raise additional capital to

further advance its research and development (“R&D”) programs, prepare for potential regulatory submissions, commercialize tests that receive regulatory approval, if any, operate its business, and meet its financial obligations as they come due. If the Company has insufficient funding to meet its working capital needs, it could be required to modify, delay, or reduce the scope of, or terminate some of, its R&D activities and/or limit or cease operations, which could harm its business, operating results, financial condition, and ability to achieve its intended business objectives. If the Company’s cash, cash equivalents, and marketable securities are not sufficient to enable the Company to fund its operations, the Company may need to raise additional funds through the sale of additional equity, debt financings, grants, or strategic alliances with third parties, which may be dilutive to existing stockholders. There can be no assurances that such funding sources will be available at terms acceptable to the Company, or at all.

Risks and Uncertainties

The Company is subject to risks and uncertainties common to companies in the biopharmaceutical and diagnostic test industries, including, but not limited to, risks associated with failure or unsatisfactory results of nonclinical and clinical studies, the need for significant capital to fund clinical trials and development of its diagnostic test candidates, dependence on strategic relationships with collaboration partners and key personnel, the ability to develop, secure, and protect proprietary technology rights, compliance with government regulations, the development of technological innovations by competitors, and dependence on third-party service providers.

The Company relies on a limited number of third-party manufacturers and service providers, some of whom are sole suppliers or service providers, for a portion of the components, accessories, reagents, materials, and equipment that it uses in its operations. A disruption or interruption in supply from these suppliers, or in the operations of such suppliers, would negatively impact the Company’s business, supply chain, and laboratory operations.

The Company’s business and operations may be affected by worldwide economic conditions, which may continue to be impacted by global macroeconomic challenges, such as the effects of the ongoing geopolitical conflicts, tariffs, and uncertainty in the financial markets, including disruptions in the banking industry and inflationary trends.

Recently Issued Accounting Standards Not Yet Adopted

In November 2024, the Financial Accounting Standards Board (FASB) issued ASU 2024-03, Income Statement (Subtopic 220-40): Reporting Comprehensive Income - Expense Disaggregation Disclosures, which requires an entity to disclose on an annual and interim basis, disaggregated information about specific income statement expense categories. The standard will be effective for annual reporting periods beginning after December 15, 2026, and interim reporting periods beginning after December 15, 2027, with early adoption permitted. The guidance should be applied prospectively with the option to apply the standard retrospectively. The Company is currently evaluating the disclosure requirements related to this new standard.

In May 2025, the FASB issued ASU No. 2025-03, Determining the Accounting Acquirer in the Acquisition of a Variable Interest Entity, which revises current guidance for determining the accounting acquirer for a transaction effected primarily by exchanging equity interests in which the legal acquiree is a variable interest entity that meets the definition of a business. The amendments require that an entity consider the same factors that are currently required for determining which entity is the accounting acquirer in other acquisition transactions. The standard is effective for annual reporting periods beginning after December 15, 2026, and interim reporting periods within those annual reporting periods, with early adoption permitted. The standard is required to be applied prospectively. The Company is evaluating adoption timing and the impact the standard will have on its financial statements and related disclosures.

In December 2025, the FASB issued ASU 2025-11, Interim Reporting (Topic 270): Narrow-Scope Improvements. ASU 2025-11 improves clarity for interim financial reporting requirements under the existing guidance within ASC 270, Interim Reporting. ASU 2025-11 is effective for public entities with annual periods beginning after December 15, 2027, with early adoption permitted. The Company is currently evaluating the impact of ASU 2025-11 on its financial statements and related disclosures.

8

Note 2—Certain Balance Sheet Components

Cash, Cash Equivalents, and Restricted Cash

Cash and cash equivalents include cash deposits in banks and highly liquid investments that are readily convertible to cash (maturity of three months or less at the time of purchase).

Restricted cash consists of funds held or designated to satisfy the requirements of certain agreements that are restricted in their use. As of June 30, 2026 and December 31, 2025, the Company’s restricted cash consisted of cash deposits required to support irrevocable standby letters of credit provided to the landlord pursuant to certain lease agreements. The Company determines current or non-current classification of restricted cash on the consolidated balance sheets based on the expected duration of the restriction. The Company’s restricted cash totaled $9.6 million and $9.1 million at June 30, 2026, and December 31, 2025, respectively.

Property and Equipment

Property and equipment, net consists of the following (in thousands):

		June 30, 2026				December 31, 2025
Leasehold improvements		$	147,924			$	147,924
Laboratory machinery and equipment			43,751				40,669
Machinery and equipment			7,514				7,514
Computer hardware and software			4,925				4,905
Furniture and fixtures			4,140				4,140
Construction in progress			9,965				847
Subtotal			218,219				205,999
Less: accumulated depreciation and amortization			(61,258	)			(50,223	)
Total property and equipment, net		$	156,961			$	155,776

 Depreciation expense related to property and equipment was $5.9 million and $5.7 million for the three months ended June 30, 2026, and 2025, respectively and $11.8 million and $11.5 million for the six months ended June 30, 2026 and 2025, respectively, and were recorded in both R&D expenses and general and administrative (“G&A”) expenses in the condensed consolidated statements of operations.

9

Accrued compensation and other related benefits

Accrued compensation and other related benefits consists of the following (in thousands):

		June 30, 2026				December 31, 2025
Accrued bonuses		$	7,597			$	12,141
Accrued payroll and related expenses			917				916
Accrued other compensation related benefits			477				367
Total accrued compensation and other related benefits		$	8,991			$	13,424

Intangible Assets, net

The following table presents details of intangible assets, net as of June 30, 2026 (in thousands):

		June 30, 2026
		Gross Carrying Amount				Accumulated Amortization				Net Carrying Amount				Remaining Weighted- Average Useful Life (in years)
Intangible assets acquired:
Acquired developed technology		$	5,509			$	(2,992	)		$	2,517				2.9
Customer relationships			529				(288	)			241				2.9
Total intangible assets acquired		$	6,038			$	(3,280	)		$	2,758

The following table presents details of intangible assets, net as of December 31, 2025 (in thousands):

		December 31, 2025
		Gross Carrying Amount				Accumulated Amortization				Net Carrying Amount				Remaining Weighted- Average Useful Life (in years)
Intangible assets acquired:
Acquired developed technology		$	5,509			$	(2,498	)		$	3,011				3.4
Customer relationships			529				(240	)			289				3.4
Total intangible assets acquired		$	6,038			$	(2,738	)		$	3,300

Amortization expense of finite-lived intangible assets was $0.3 million for the three months ended June 30, 2026 and 2025, respectively, and $0.5 million for the six months ended June 30, 2026 and 2025, respectively.

The following table summarizes the Company’s estimated future amortization expense of finite-lived intangible assets as of June 30, 2026 (in thousands):

Year Ending June 30,		Total
2026 (remainder of year)		$	464
2027			1,006
2028			1,006
2029			282
Total		$	2,758

10

Note 3— Fair Value Measurements

The preparation of the Company’s unaudited interim condensed consolidated financial statements in accordance with U.S. GAAP requires certain assets and liabilities to be reflected at their fair value. Fair value is defined as the exchange price, or exit price, representing the amount that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants on the measurement date. Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs. The fair value hierarchy contains three levels of inputs that may be used to measure fair value, in accordance with ASC 820, Fair Value Measurement, the first two are considered observable and the last is considered unobservable. These levels are as follows:

● Level 1—inputs, which include unadjusted quoted prices in active markets for identical assets or liabilities that the Company has the ability to access;

● Level 2— inputs, which include observable inputs other than Level 1 inputs, such as quoted prices for similar assets or liabilities in active markets, quoted prices for identical or similar assets or liabilities in markets that are not active, or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the asset or liability; and

● Level 3— inputs, which include unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the underlying asset or liability. Level 3 assets and liabilities include those whose fair value measurements are determined using pricing models, discounted cash flow methodologies, or similar valuation techniques, as well as significant management judgment or estimation.

To the extent the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in determining fair

value is greatest for instruments categorized in Level 3. Marketable securities that are classified as available-for-sale are recorded at estimated fair value and are included in Level 1 or Level 2 of the fair value hierarchy. The Company classifies its money market funds

and U.S. treasury securities, which are valued based on quoted market prices in active markets with no valuation adjustment, as Level 1 assets within the fair value hierarchy.

The categorization of a financial instrument within the valuation hierarchy is based upon the lowest level of input that is significant to the fair value measurement. The carrying value of cash, accounts payable, accrued expenses and other current liabilities and convertible note, related party approximate fair value because of the short-term nature of those instruments.

The following table summarizes the Company’s financial assets and liabilities measured at fair value on a recurring basis and their respective input levels based on the fair value hierarchy (in thousands):

		June 30, 2026
		Level 1				Level 2				Level 3				Total
Assets:
Cash equivalents:
Money market funds		$	50,261			$	—			$	—			$	50,261
U.S. treasury securities			17,658				—				—				17,658
Total cash equivalents			67,919				—				—				67,919
Short-term marketable securities:
U.S. treasury securities			16,557				—				—				16,557
Total short-term marketable securities			16,557				—				—				16,557
Total assets subject to fair value measurements on a recurring basis		$	84,476			$	—			$	—			$	84,476
Liabilities:
Convertible note, at fair value		$	—			$	—			$	41,700			$	41,700
Total liabilities subject to fair value measurements on a recurring basis		$	—			$	—			$	41,700			$	41,700

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		December 31, 2025
		Level 1				Level 2				Level 3				Total
Assets:
Cash equivalents:
Money market funds		$	40,320			$	—			$	—			$	40,320
U.S. treasury securities			29,638				—				—				29,638
Total cash equivalents			69,958				—				—				69,958
Short-term marketable securities:
U.S. treasury securities			138,106				—				—				138,106
Total short-term marketable securities			138,106				—				—				138,106
Total assets subject to fair value measurements on a recurring basis		$	208,064			$	—			$	—			$	208,064
Liabilities:
Convertible note, at fair value		$	—			$	—			$	41,600			$	41,600
Total liabilities subject to fair value measurements on a recurring basis		$	—			$	—			$	41,600			$	41,600

There were no transfers between Level 1, Level 2 and Level 3 during the periods presented.

The Company elected to measure the Convertible Note issued to Exact Sciences Corporation (the “Exact Convertible Note”) using the fair value option at each reporting date. See Note 8 for more information regarding the Convertible Note issued to Exact Sciences.

The fair value of the Exact Convertible Note at June 30, 2026 and December 31, 2025 was determined using a Monte Carlo Simulation Model, which includes significant inputs not observable in the market, which causes it to be classified as a Level 3 measurement within the fair value hierarchy. The methodology consists of simulating the value of the stock price to maturity or early conversion to determine the timing and amount of the debt payoff. The payoff amount is then discounted back to the valuation date considering a Company specific cost of debt.

The significant unobservable inputs used in the valuation included the following:

		June 30, 2026				December 31, 2025
Estimated Stock Price		$	3.28			$	2.44
Credit Spread			9.6	%			8.9	%

The fair value of the Exact Convertible Note may change significantly by the estimated stock price and credit spread, impacting the Company’s assumptions regarding probabilities of outcomes used to estimate the fair value. The estimates of fair value may not be indicative of the amounts that could be realized in a current market exchange. Any increase or decrease in the fair value of the Company’s estimated stock price would result in an increase or decrease in the valuation of the Exact Convertible Note. A change in the credit spread would not impact the estimated fair value of the Company’s stock price. Accordingly, the use of a different market assumption may have a material effect on the estimated fair value amounts, and such changes could impact the Company’s results of operations in future periods. The change in fair value as of June 30, 2026 was $0.1 million and is recognized as interest expense and included in other expense, net in the condensed consolidated statements of operations.

The change in the fair value of the Exact Convertible Note is summarized in the following table (in thousands):

Balance at December 31, 2025		$	41,600
Change in fair value			100
Balance at June 30, 2026		$	41,700

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Note 4— Investments in Marketable Securities

Investments in marketable available-for-sale securities consisted of the following (in thousands):

		June 30, 2026
		Amortized Cost				Gross Unrealized Gain				Gross Unrealized Loss				Estimated Fair Value
Cash equivalents:
Money market funds		$	50,261			$	—			$	—			$	50,261
U.S. treasury securities			17,658				—				—				17,658
Total cash equivalents			67,919				—				—				67,919
Short-term marketable securities:
U.S. treasury securities			16,558				—				(1	)			16,557
Total short-term marketable securities			16,558				—				(1	)			16,557
Total assets measured at fair value		$	84,477			$	—			$	(1	)		$	84,476

		December 31, 2025
		Amortized Cost				Gross Unrealized Gain				Gross Unrealized Loss				Estimated Fair Value
Cash equivalents:
Money market funds		$	40,320			$	—			$	—			$	40,320
U.S. treasury securities			29,631				7				—				29,638
Total cash equivalents			69,951				7				—				69,958
Short-term marketable securities:
U.S. treasury securities			138,029				77				—				138,106
Total short-term marketable securities			138,029				77				—				138,106
Total assets measured at fair value		$	207,980			$	84			$	—			$	208,064

As of June 30, 2026 and December 31, 2025, the Company has not realized any impairment charges on its marketable securities related to expected credit losses. As of June 30, 2026 and December 31, 2025, the aggregate difference between the amortized cost and fair value of each security in an unrealized loss position was deemed to be minimal. Since any provision for expected credit losses for a security is limited to the amount the fair value less than its amortized cost, no allowance for expected credit loss was deemed necessary as of June 30, 2026 and December 31, 2025. The Company does not intend to sell the investments and it is not more likely than not that the Company will be required to sell the investments before recovery of their amortized cost basis, which may be maturity. None of the available-for-sale securities held as of June 30, 2026 and December 31, 2025 have been in an unrealized loss position for more than one year. See Note 3 for further information regarding the fair value of the Company’s investments in marketable securities.

There were no long-term marketable securities as of June 30, 2026, and December 31, 2025.

Note 5—Taxes

The Company had no current or deferred income tax expense or benefit during the three and six months ended June 30, 2026 and 2025. Deferred income taxes reflect the net tax effects of loss and credit carryforwards, as well as temporary differences between the carrying amounts of assets and liabilities for financial reporting and income tax purposes. The realization of these deferred tax assets is dependent upon future taxable income, the amount and timing of which are currently uncertain. All of the Company's deferred tax assets—which include net operating loss carryforwards, tax credits related primarily to research and development, capitalized research and development costs, and operating lease liabilities—continue to have a full valuation allowance as of June 30, 2026. The Company will maintain this full valuation allowance until there is sufficient evidence to support the recoverability of its deferred tax assets.

13

Note 6—Revenue

Exclusive License Agreement with Exact Sciences Corporation (“Exact Sciences”)

In August 2025, the Company signed an exclusive collaboration and license agreement with Exact Sciences (the “Exact Sciences License Agreement”) to commercialize the Company’s blood-based screening test for colorectal cancer (“CRC”) in the United States (“U.S.”). The Exact Sciences License Agreement was deemed effective for accounting purposes upon receipt of approval from the relevant governmental authority on November 7, 2025 (the “Antitrust Clearance Date”). On March 23, 2026, Abbott Laboratories (“Abbott”) completed its acquisition of Exact Sciences, and Exact Sciences became a subsidiary of Abbott.

Pursuant to the Exact Sciences License Agreement, the Company granted Exact Sciences (a) a non-exclusive, fully paid, royalty-free, sublicensable (subject to certain restrictions) license under certain of the Company’s intellectual property rights to develop in accordance with the development plan certain in vitro, blood-based products or services for diagnosis, screening or evaluation of CRC or colorectal pre-cancer (excluding certain multi-cancer tests) (each a “Collaboration Product”) for all uses and purposes, excluding the diagnosis, screening or evaluation of measurable residual disease (the “Field”), (b) a co-exclusive, royalty-bearing, sublicensable (subject to certain restrictions) license under certain of the Company’s intellectual property rights to commercialize Collaboration Products that are laboratory developed tests until the later of (i) the date of approval by the FDA of a premarket approval application for a class III medical device for CRC or colorectal pre-cancer that meets certain requirements for the first Collaboration Product and (ii) antitrust clearance, which occurred on November 7, 2025 and (c) upon approval by the FDA of a Collaboration Product, an exclusive, royalty bearing, sublicensable (subject to certain restrictions) license under certain of the Company’s intellectual property rights to commercialize Collaboration Products in the Field in the U.S. In addition, the Company granted Exact Sciences a non-exclusive, worldwide license to manufacture Collaboration Products for purposes of developing and commercializing Collaboration Products as expressly permitted above. Collaboration Products exclude certain future CRC products for which Exact Sciences is granted a certain right of first negotiation in the U.S.

Pursuant to the Exact Sciences License Agreement, the Company received a one-time, non-refundable, non-creditable, upfront payment of $75.0 million from Exact Sciences on November 3, 2025 as partial consideration for the rights and license granted. The Company is also eligible to receive up to $700.0 million in certain development and regulatory milestones; annual development payments of up to $20.0 million per year over three years for funding of R&D development expenses leveraging the technology for those three years; and tiered royalties ranging from low to high double-digit percentages on U.S. sales of any commercial products that may result from the collaboration, subject to customary deductions under certain circumstances.

The Exact Sciences License Agreement is subject to termination by either party for the other party’s uncured material breach or its insolvency. Subject to certain limitations, the Company and Exact Sciences both have certain termination for convenience rights, exercisable upon sufficient prior written notice. Specifically, the Company's right to terminate for convenience may be exercised if Exact Sciences ceases commercialization activities for all Collaboration Products; or if there is a patent challenge with respect to the Company’s patent rights in the U.S.; or if Exact Sciences’ licensees commercially launch, as a standalone product, the in vitro, blood-based product for the diagnosis, screening or evaluation of colorectal cancer in the U.S. that Exact Sciences is developing. Exact Sciences may terminate the agreement in its entirety, upon prior written notice to the Company, upon earlier of not meeting a

certain development milestone event or by January 1, 2028.

Exact Sciences also has a right to terminate the collaborative activities under the Exact Sciences License Agreement at certain specified points during the collaboration term. Other customary termination rights are further provided in the Exact Sciences License Agreement.

The Company concluded at the commencement of the arrangement that Exact Sciences was a customer and the Exact Sciences License Agreement should be accounted for under ASC 606. Performance obligations identified under the Exact Sciences License Agreement includes the delivery of intellectual property and licenses related to development, co-exclusive commercialization, manufacturing, and data; research and development services; the delivery of the exclusive commercialization license; technology transfers; and a material right granted to the customer for certain laboratory tests that will be billed at cost by the Company.

The promises related to the development license, co-exclusive commercialization license, manufacturing license, and data license were considered functional intellectual property and determined to be distinct from the remaining promises in the Exact Sciences License Agreement. These licenses were delivered at the same time, therefore, they are considered one performance obligation at contract inception.

The Company determined the transaction price under ASC 606 at the inception of the Exact Sciences License Agreement to be $143.4 million, consisting of the $75.0 million up front payment, $60.0 million reimbursement for development costs, and $8.4 million allocated to the Exact Sciences License Agreement from the proceeds received in the Exact Sciences Convertible Note (see Note 8). The reimbursement for development costs includes $20.0 million of variable consideration per year, that is expected to be paid by Exact over a three year period from the effective date of the contract.

14

The Exact Sciences License Agreement includes $700.0 million milestone payments, of which $100.0 million is payable upon FDA approval of the Company’s initial version of a Collaboration Product, $100.0 million is payable upon first-line FDA approval for the next-generation test contingent on meeting predefined performance benchmarks, and $500.0 million is payable upon a Collaboration Product being rated as a first-line A or B test in the USPSTF guidelines or meeting certain payer contracted coverage requirements. If the predefined performance benchmarks are not achieved, or if the Collaboration Product is rated as a second-line A or B test in the USPSTF guidelines, then each respective milestone payment may be reduced as provided in the Agreement. The Company determined that these development and regulatory events are not within the Company’s control or the licensee’s control and are not considered probable of being achieved until those approvals are received. Accordingly, the Company has fully constrained the milestone payments. The Exact Sciences License Agreement also includes sales-based royalty payments, determined on a level of sales for which the license is deemed to be the predominant item to which the royalties relate. The Company will recognize revenue for these payments at the later of (i) when the related sales occur, or (ii) when the performance obligation to which some or all of the royalty has been allocated has been satisfied or partially satisfied.

The Company allocated the transaction price at inception to each performance obligation based on a relative standalone selling price (“SSP”) basis. The SSP of the exclusive commercialization license was determined using an income approach, considering the discounted cash flows related to the license. SSPs for each of the data license, development license, and manufacturing license were determined using a replacement cost approach. The SSPs of the technology transfers and research & development services were determined utilizing the cost-plus margin approach, considering the cost for services and an assumed margin that a market participant would pay to obtain the services. The SSP of the material right related to the laboratory tests was also determined utilizing the cost-plus margin approach, based on the expected reimbursed cost of the laboratory tests and an assumed margin that a market participant would charge to perform the laboratory tests.

The Company recognizes the revenue for the intellectual property, exclusive commercialization license and, the technology transfers at a point in time when the performance obligations are satisfied. Revenue related to the research and development services is recognized over time using a cost input method as services are performed while the revenue associated with the material right will be recognized over time using an output method as the laboratory tests are performed, which the Company believes best depicts the transfer of control to the customer.

The following table summarizes the changes in deferred revenue (in millions):

Balance at December 31, 2025		$	56.3
Additions to deferred revenue during the six months ended June 30, 2026			20.0
Recognized in revenue during the six months ended June 30, 2026			(5.2	)
Balance at June 30, 2026 (1)		$	71.1

⁽¹⁾ During the three and six months ended June 30, 2026, the Company recognized $1.5 million and  $5.2 million revenue, respectively, related to the research and development services provided during the period. A related contract asset and deferred revenue were also recorded, as the contractual right to payment for collaboration services under the Exact Sciences License Agreement has not yet been raised. In accordance with ASC 606, contract assets and liabilities associated within an agreement are considered interdependent and are presented net on the condensed balance sheets. Accordingly, the related contract asset was netted against deferred revenue balance as of June 30, 2026.

As of June 30, 2026, the aggregate transaction price allocated to unsatisfied performance obligations was $111.1 million, which consists of deferred revenue of $71.1 million and variable consideration for the reimbursement of developmental services of $40.0 million, and is expected to be recognized upon transfer of control of the underlying promised goods or services to Exact Sciences as follows: $92.8 million is expected to be recognized upon transfer of the exclusive commercialization license, $0.4 million is expected to be recognized upon satisfaction of the technology transfers, $14.3 million is expected to be recognized as the research and development services are performed and $3.6 million is expected to be recognized for the material right as the laboratory tests are performed.

15

Service and Other Revenue

The Company derives revenue from the sale and distribution of tests and services through its U.K.-based subsidiary, Freenome Ltd. Revenue is recognized at a point in time as the Company satisfies its performance obligations by transferring the goods and services to its customers.

The following table summarizes the revenue by type (in millions):

		Three Months Ended June 30,								Six Months Ended June 30,
Revenue type		2026				2025				2026				2025
EarlyCDT Lung royalties		$	0.4			$	0.3			$	0.8			$	0.5
EarlyCDT Lung test kits			0.3				0.7				0.4				0.8
EarlyCDT Lung test plates			0.1				0.1				0.2				0.3
Total revenue		$	0.8			$	1.1			$	1.4			$	1.6

Note 7—Exclusive License and Option Agreement with Roche

In November 2025, the Company entered into an exclusive license and option agreement with Roche Sequencing Solutions, Inc. (‘‘Roche Sequencing’’), and a promissory note agreement with Roche Holdings (‘‘Roche Promissory Note Agreement’’) related to a convertible promissory note (the ‘‘Roche Convertible Note’’) under which the Company received total proceeds of $75.0 million (see Note 8).

The exclusive license and option agreement with Roche Sequencing (the ‘‘Roche License and Option Agreement’’) grants Roche Sequencing two rights: (a) an exclusive option (the ‘‘Option’’) to obtain an exclusive, royalty-bearing, sublicensable (subject to certain restrictions) license to certain of the Company’s intellectual property rights for the manufacture and sale of kitted assays for cancer screening, including for colorectal cancer and lung cancer (the ‘‘Licensed Products’’), outside the U.S.; and (b) in the event that the Company seeks to enter into a partnering transaction to offer centralized testing services for cancer screening outside the U.S., a preferred partner right to negotiate with the Company a definitive agreement for such partnering transaction. In addition, the Company agreed to conduct an evaluation of the Company’s cancer detection assays using Roche Sequencing’s sequencer (the ‘‘SBX Platform’’) for no more than two years (the ‘‘Evaluation Period’’), beginning when the SBX Platform is delivered to the Company by Roche Sequencing.

Under the Roche License and Option Agreement, Roche Sequencing is obligated to pay the Company a $10.0 million option exercise fee within thirty (30) days of its written notice to exercise the option.

If Roche Sequencing exercises the Option, the Company may receive up to $100.0 million in milestone payments as well as royalties on non-U. S. test sales that range from low single-digits to mid-teens, depending on sales of the Licensed Products. The Company may also receive up to $24.0 million in SBX research and development related milestones payments.

The Option can be exercised anytime from November 14, 2025 (date of the Roche License and Option agreement) through and until one year after the earlier of (i) Licensed Products for at least five separate indications, including CRC and lung cancer as two of such five separate indications, have been approved or cleared by the FDA, or (ii) (x) Licensed Products for CRC and lung cancer have been approved or cleared by the FDA, and (y) the Company has launched Licensed Products as laboratory developed tests under applicable regulatory requirements in the U.S., or Licensed Products have been approved or cleared by the FDA, for three additional separate indications other than CRC and lung cancer. The agreement terminates upon the earlier of (i) the expiration of the royalty term for all Licensed Products in the Territory if the Customer exercises the Option, or (ii) if Roche does not exercise the Option, three years after the Company has made all commercial assays of the Company available on the SBX Platform or the termination of the SBX Evaluation Plan and Implementation Plan. The Roche License and Option Agreement is subject to termination by either party for the other party’s uncured material breach. Additionally, both the Company and Roche Sequencing have certain specific termination rights, upon sufficient prior written notice. The Company may terminate if, following the exercise of the Option, Roche Sequencing engages in any patent challenge with respect to any licensed patent. The Company also has termination rights if, following receipt of regulatory approval for a licensed product, Roche Sequencing (i) does not initiate commercialization activities for at least one licensed product during the twelve (12) month period following the date of such regulatory approval, or (ii) ceases all commercialization activities for all licensed products for a continuous period of twelve (12) months. Conversely, Roche Sequencing may terminate the agreement if there is a Change of Control at the Company.

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The Company determined that the Roche License and Option Agreement and the Roche Promissory Note Agreement should be assessed as a single combined transaction as the agreements were negotiated and entered into together, with a single commercial objective. The Company allocated the difference between the total upfront proceeds of $75.0 million and the initial fair value of the Roche Convertible Note (see Note 9) to the Roche License and Option Agreement. The Company recorded the $15.0 million proceeds allocated to the Roche License and Option Agreement as other long-term liabilities as of June 30, 2026 and December 31, 2025, respectively.

The Roche License and Option Agreement does not meet the criteria to be considered a contract under ASC 606 as of June 30, 2026 as the parties do not have enforceable rights until Roche Sequencing exercises the Option or delivers the SBX Platform to the Company. As of June 30, 2026, and through the date the consolidated financial statements are issued, Roche Sequencing has not exercised the Option and has not provided the SBX Platform to the Company. Following the exercise of the Option or delivery of the SBX Platform, the Roche License and Option Agreement will meet the criteria of a contract within the scope of ASC 606. The nature of the performance obligations identified in the Roche License and Option Agreement, and the satisfaction of those performance obligations, will vary depending on the timing of the exercise of the Option or delivery of the SBX Platform.

Note 8—Debt

Exact Note Purchase Agreement with Exact Sciences

In August 2025, the Company entered into a Convertible Promissory Note Purchase Agreement with Exact Sciences (‘‘Exact Sciences Note Purchase Agreement’’), pursuant to which the Company issued a senior unsecured convertible note (‘‘Exact Convertible Note’’) with an aggregate principal amount of $50.0 million to Exact Sciences, which remains fully outstanding as of June 30, 2026.

The Exact Convertible Note bears interest at 5% per annum and matures on the five-year anniversary date of August 12, 2030. Interest is payable quarterly in arrears on the last business day of each calendar quarter, beginning on September 30, 2025. The Exact Convertible Note will automatically convert into shares of the Company’s common stock upon the occurrence of a public listing, provided that, the volume-weighted average sales price over a period of 10 consecutive trading days exceeds 1.5 times the original offer price per share following the listing.

The Exact Convertible Note is convertible at any time prior to the maturity date, at the holder’s option, into shares of the Company’s most senior series of preferred stock (if converted prior to a public filing) or into shares of the Company’s common stock (if converted following a public filing). The conversion is calculated by dividing the total principal and accrued and unpaid interest by the applicable conversion price. The conversion price is (i) the original issue price of the Company’s most senior series of preferred stock if prior to a public offering, or (ii) a price per share equal to 1.5 times the original public listing price following a public offering.

In the event of a default, Exact Science may accelerate the maturity date of the Exact Convertible Note and require full payment in cash of the principal amount, plus accrued and unpaid interest. Events of default include, among other things: failure to timely pay amounts due, the Company executing a general assignment for the benefit of creditors, the Company filing a petition or action for relief under any bankruptcy statute, or an involuntary petition being filed against the Company under any bankruptcy statute.

The Exact Sciences Note Purchase Agreement was entered into in connection with the Exact Sciences License Agreement (see Note 6). These agreements were evaluated as a single contract for revenue recognition purposes under ASC 606 because they were negotiated as a package with a single commercial objective, and the consideration in one agreement is dependent on the price of the other agreement. Accordingly, the principal amount received by the Company in excess of the initial fair value of the Exact Convertible Note was included in the total transaction price of the Exact Sciences License Agreement and initially recorded as deferred revenue as of issuance date. Refer to Note 6 for further discussion of the revenue recognized related to the Exact Sciences License Agreement during the period ended June 30, 2026.

The Company elected the fair value option to account for the Exact Convertible Note. Issuance costs incurred were not deferred but were recognized as an expense during the year ended December 31, 2025. The Company measured the Exact Convertible Note, including accrued interest, at fair value upon issuance, resulting in a recorded fair value of $41.6 million as of the issuance date. The difference between the fair value of the Exact Convertible Note and the proceeds received of $50.0 million was included in the transaction price of the Exact Sciences License Agreement and recorded as deferred revenue as of the issuance date (see Note 6). The change in fair value as of June 30, 2026 was $0.1 million and is included in interest expense in the condensed consolidated statements of operations. As of June 30, 2026, the carrying value of the Exact Convertible Note was $41.7 million.

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Promissory Note Agreement with Roche Holdings, a related party

In November 2025, the Company executed the Roche Promissory Note Agreement with Roche Holdings, a related party, for a $75.0 million convertible promissory note, bearing an annual interest rate of 5%. The note is effective November 17, 2025 and matures May 17, 2027.

The Roche Convertible Note will automatically convert upon the earliest of: (i) the closing of the issuance and sale of capital stock of the Company in the Company’s underwritten initial public offering; (ii) any other transaction (such as a SPAC Transaction) that is not a Corporate Transaction (as defined in the Roche Promissory Note Agreement) but results in a class of the Company's shares or any successor entity's shares being registered under the Securities Exchange Act of 1934, as amended; or (iii) the next equity financing for shares of preferred stock.

The Roche Convertible Note is convertible at any time prior to the maturity date, at Roche’s option, into shares of the Company’s most senior series of preferred stock (if converted prior to a public filing) or into shares of the Company’s common stock (if converted following a public filing). The conversion is calculated by dividing the total principal and accrued and unpaid interest by the applicable conversion price, which is: (a) prior to a public listing of the Company, (x) the original issue price per share of the Company’s most senior series of preferred stock if prior to a public offering, or (y) the price paid per share for preferred stock by investors in a next equity financing times 80%; or (b) following a public listing of the Company, a price per share equal to 1.2 times the original public listing price.

In the event of a default, Roche may accelerate the maturity date of the Roche Convertible Note and require full payment in cash of the principal amount, plus accrued and unpaid interest. Events of default include, among other things: failure to timely pay amounts due, the Company executing a general assignment for the benefit of creditors, the Company filing a petition or action for relief under any bankruptcy statute, or an involuntary petition being filed against the Company under any bankruptcy statute.

The Roche Convertible Note and the Roche License and Option Agreement (collectively, the ‘‘Roche Agreements’’) were evaluated as a single contract as they were negotiated as a package with a single commercial objective, and the consideration in one agreement is dependent on the price of the other. The Company received total proceeds of $75.0 million upon execution of the Roche Agreements. The Company allocated the $75.0 million upfront proceeds received under the Roche Agreements to the Roche Convertible Note based on its fair value on issuance date of  $60.0 million and to the Roche License and Option Agreement based on the excess of the total proceeds received over the issuance date fair value of the Convertible Note of $15.0 million.

The Roche Convertible Note represents a liability under ASC 480, Distinguishing Liabilities from Equity (‘‘ASC 480’’), and was initially recorded based on the initial amounts allocated less applicable issuance costs. The Roche Convertible Note will subsequently be accounted for using the interest method over the contractual life of the instrument in accordance with ASC 835-30. The Company recorded $0.9 million and $1.9 million of contractual interest expense related to the Roche Convertible Note during the three and six months ended June 30, 2026, respectively. As of June 30, 2026, the carrying value of the Roche Convertible Note was $65.5 million. Upon the Closing of the Business Combination, the Roche Convertible Note automatically converted into shares of New Freenome common stock in accordance with the terms of the note. See Note 17.

The following table summarizes the Company’s principal obligations for convertible notes as of June 30, 2026 (in millions):

Year Ending June 30,		Exact Sciences Convertible Note				Roche Convertible Note				Total
2026 (remainder of year)		$	—			$	—			$	—
2027			—				75.0				75.0
2028			—				—				—
2029			—				—				—
2030			50.0				—				50.0
Total principal balance			50.0				75.0				125.0
Change in fair value of convertible notes			0.1				—				0.1
Amount allocated to Exact Sciences License			(8.4	)			—				(8.4	)
Unamortized debt discount and issuance costs			—				(9.5	)			(9.5	)
Net carrying value		$	41.7			$	65.5			$	107.2

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Note 9—Common Stock

The Company has reserved shares for the issuance of common stock as follows:

		June 30, 2026				December 31, 2025
Convertible preferred stock common stock equivalent, if converted			213,907,881				213,907,881
Shares available for issuance under 2016 Equity Incentive Plan			11,282,298				10,804,104
Stock-based awards outstanding			43,506,948				43,985,142
Warrants to purchase common stock			478,060				478,060
Convertible notes(2)			17,208,781				17,170,902
Total			286,383,968				286,346,089

⁽²⁾ The Company reasonably assumed the Convertible Notes will convert upon a public listing as defined in Note 8.

Retirement of the Treasury Shares

In February 2025, the Board of Directors approved the retirement of the 3,274,353 shares of common stock that were repurchased by the Company in 2019. Upon the formal retirement of treasury shares, the acquisition cost of repurchased shares of $2.6 million was reclassified out of treasury stock and recognized in additional paid-in-capital. The retired treasury shares revert to the status of authorized and unissued common shares.

Note 10 —Convertible Preferred Stock

The Company’s redeemable convertible preferred stock as of June 30, 2026 and December 31, 2025, consisted of the following:

		Shares Authorized				Shares Issued and Outstanding				Conversion Price				Aggregate Liquidation Preference				Net Carrying Value
														(in thousands)
Series Seed-1 preferred			3,360,000				3,360,000			$	0.23810			$	800			$	800
Series Seed-2 preferred			9,092,395				9,092,395			$	0.61051				5,551				5,551
Series A preferred			22,660,320				22,660,320			$	3.07255				69,625				69,518
Series B preferred			36,207,457				36,207,457			$	4.55707				165,000				164,659
Series C preferred			40,826,799				40,826,799			$	6.61330				270,000				269,679
Series D preferred			39,775,664				39,775,644			$	7.52334				299,246				299,151
Series E preferred			25,284,991				24,942,143			$	11.10351				276,945				290,567
Series F preferred			36,493,093				35,677,074			$	7.39866				263,963				263,655
Total			213,700,719				212,541,832							$	1,351,130			$	1,363,580

The Company evaluated the rights, preferences, and privileges of each series of convertible preferred stock and concluded that there were no freestanding derivative instruments or any embedded derivatives requiring bifurcation. As of June 30, 2026 the convertible preferred stock has the following rights, preferences, privileges, and restrictions:

● Dividends Rights – The holders of shares of convertible preferred stock (the “preferred stockholders”) are entitled to receive non-cumulative dividends, as adjusted for stock splits, dividends, reclassifications or the like, prior and in preference to any declaration or payment of any dividends to the holders of shares of the Company’s common stock (“common stock,” and the holders of common stock, the “common stockholders”), when and if declared by the Company’s Board of Directors (the “Board”), at a rate of 6.0% of the applicable Original Issue Price (as defined) per annum on each outstanding share of convertible preferred stock. The Board has not declared any dividends to date.

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● Voting Rights – The preferred stockholders are entitled to voting rights equal to the number of whole shares of common stock into which each share of convertible preferred stock could be converted. In addition, so long as at least 2,000,000 shares of Series A preferred stock are outstanding, the holders of shares of Series A preferred stock, voting together as a separate class, are entitled to elect one member of the Board. So long as at least 2,000,000 shares of Series B preferred stock are outstanding, the holders of shares of Series B preferred stock, voting together as a separate class, are entitled to elect one member of the Board. So long as at least 2,000,000 shares of Series C preferred stock are outstanding, the holders of shares of Series C preferred stock, voting together as a separate class, are entitled to elect one member of the Board. So long as at least 2,000,000 shares of Series E preferred stock are outstanding, the holders of shares of Series E preferred stock, voting together as a separate class, are entitled to elect two members of the Board. The common stockholders, voting exclusively and as a separate class, are entitled to elect one member of the Board. The preferred stockholders and the common stockholders, voting together as a single class on an as-converted basis, are entitled to elect any remaining members of the Board.

● Liquidation Rights – In the event of any liquidation, dissolution or winding up of the Company, including certain mergers, consolidations, and asset sales, either voluntary or involuntary, the holders of shares of convertible preferred stock then outstanding, on a pari passu basis, are entitled to receive, prior to and in preference to the common stockholders, an amount equal to the greater of (i) the applicable Original Issue Price, plus declared but unpaid dividends, or (ii) such amount per share as would have been payable had all shares of convertible preferred stock been converted into shares of common stock, as adjusted for stock splits, dividends, reclassifications or the like. If, upon occurrence of such an event, the assets and funds distributed among the holders of shares of convertible preferred stock are insufficient to permit the above payment to such holders, then the assets and funds of the Company legally available for distribution to the holders of shares of convertible preferred stock will be distributed ratably among the holders in proportion to the preferential amount each such holder is otherwise entitled to receive. Following these payments, the remaining assets and surplus funds of the Company, if any, will be distributed ratably among the common stockholders based on the number of shares of common stock held.

● Redemption Rights – The convertible preferred stock is not redeemable by the preferred stockholders except in connection with a Deemed Liquidation Event (as defined) which does not include the dissolution of the Company.

● Conversion Rights – Each share of preferred stock is convertible at the option of the holder at any time after the date of issuance into the number of shares of common stock determined by dividing the Original Issue Price by the Conversion Price (as defined). The Conversion Price for each series of convertible preferred stock was initially equal to the Original Issue Price for such series, and as of June 30, 2026 each share of convertible preferred stock (other than for the Series D and E preferred stock) is convertible into one share of common stock. The issuance of the Series F preferred stock triggered the anti-dilution protection provision for the Series D and E preferred stock. As a result, the Conversion Price per share for each of the Series D and E preferred stock was adjusted from $7.54230 and $11.6670 to $7.52334 and $11.10351, respectively, and accordingly, each share of Series D and E preferred stock is convertible into 1.0025 and 1.0507 shares of common stock. Shares of convertible preferred stock automatically convert into shares of common stock upon the earlier of (i) the closing of a firm-commitment underwritten public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, of common stock where the gross proceeds to the Company are not less than $100.0 million, or (ii) the vote or written consent of the holders of at least a majority of the outstanding shares of convertible preferred stock voting together as a single class on an as-converted basis and the holders of at least a majority of the outstanding shares of Series C, D, E, and F preferred stock voting together as a single class on an as-converted basis.

● Registration Rights – The preferred stockholders have the right to request the Company to file certain registration statements with the Securities and Exchange Commission for the registration of shares related to the convertible preferred stock. The obligations of the Company regarding such registration rights include, but are not limited to, reasonable efforts to cause such registration statement to become effective, keep such registration statement effective for up to 120 days, prepare and file amendments and supplements to such registration statement and the prospectus used in connection with such registration statement, and notify each selling holder, promptly after the Company receives notice thereof, of the time when such registration statement has been declared effective or a supplement to any prospectus forming a part of such registration statement has been filed. The terms of the registration rights provide for the payment of certain expenses related to the registration of the shares, including a capped reimbursement of legal fees of a single special counsel for the preferred stockholders but do not impose any obligations for the Company to pay additional consideration to the holders in case a registration statement is not declared effective.

Note 11—Stock-Based Compensation

2016 Equity Incentive Plan

In May 2016, the Company adopted the 2016 Equity Incentive Plan, as amended (the ‘‘2016 Amended Plan’’). The Company’s employees, directors, officers, and consultants are eligible to receive awards under the 2016 Amended Plan. Under the 2016 Amended Plan, the Company may issue incentive stock options (‘‘ISOs’’), nonstatutory stock options, stock appreciation rights, restricted stock awards (‘‘RSAs’’), restricted stock unit awards (‘‘RSUs’’), and other stock awards. As of June 30, 2026, a total of 11.3 million shares of common stock were available for future issuance under the 2016 Amended Plan.

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Stock Options

The following table summarizes the Company’s stock option activity for the six months ended June 30, 2026:

		Number of Options				Weighted-Average Exercise Price (3)
Outstanding – December 31, 2025			29,512,900			$	3.19
Forfeited or canceled			(268,790	)			4.28
Outstanding – June 30, 2026			29,244,110			$	3.18
Exercisable– June 30, 2026			25,643,002			$	3.13

⁽³⁾ The Weighted-Average Exercise Price does not reflect the Repricing discussed below.

As of June 30, 2026, and December 31, 2025, there were 25,643,002, and 23,203,315 vested stock options outstanding, respectively.

Restricted Stock Units and Restricted Stock Awards

RSUs are share awards that, upon vesting, will deliver to the holder, shares of the Company’s common stock. The vesting of RSUs is conditioned on the satisfaction of two vesting requirements before the expiration date or earlier termination of the RSUs pursuant to the 2016 Amended Plan or the RSU Agreement: a time- and service-based requirement and a Liquidity Event Requirement. The Liquidity Event Requirement will be satisfied on the earliest to occur of: (i) the date that is the earlier of (1) six months after the effective date of an initial public offering of the Company and (2) March 15 of the calendar year following the year in which the initial public offering was declared effective; and (ii) the date of a change of control (as defined). Since the satisfaction of the Liquidity Event Requirement involves numerous risks and uncertainties, many of which are outside of the Company’s control, the performance condition is not deemed to be probable until the event actually occurs. Accordingly, no stock-based compensation expense for RSUs has been recognized to date and none of the RSUs have satisfied the two-tiered vesting requirement as of June 30, 2026, and 2025.

The following table summarizes the Company’s RSU activity for the six months ended June 30, 2026:

		Number of RSUs				Weighted Average Grant Date Fair Value Per Share
Outstanding– December 31, 2025			14,472,242			$	3.58
Forfeited or canceled			(209,404	)			4.19
Outstanding– June 30, 2026			14,262,838			$	3.57

Stock-Based Compensation Expense

Stock-based compensation expense was as follows (in thousands):

		Three Months Ended June 30,								Six Months Ended June 30,
Stock-based compensation recognized as:		2026				2025				2026				2025
R&D expenses		$	1,277			$	1,382			$	2,576			$	2,701
G&A expenses			1,457				1,356				3,061				2,313
Total		$	2,734			$	2,738			$	5,637			$	5,014

As of June 30, 2026, total unrecognized stock-based compensation expense was approximately $62.9 million and consisted of $12.0 million related to stock options that are expected to be recognized over a weighted-average period of approximately 2.2 years, and $50.9 million related to RSUs with performance conditions that are not considered probable of vesting.

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Option repricing

On October 24, 2025, the Board of Directors approved an option repricing (the ‘‘Repricing’’) of outstanding stock options held by certain current employees, including the Company’s named executive officers (the ‘‘Eligible Participants’’), which were granted under the 2016 Amended Plan. The Board approved the Repricing, effective October 2025 (the ‘‘Effective Date’’), upon the Compensation Committee’s recommendation, in order to retain and motivate the Company’s key contributors.

On the Effective Date, the exercise price of outstanding stock options (the ‘‘Repriced Options’’) granted under the 2016 Amended Plan and held by the Eligible Participants, specifically those with an exercise price per share greater than $2.39, was repriced to $2.39 per share (the ‘‘New Exercise Price’’). The closing of the BCA with PCSC does not qualify as a Corporate Transaction and would not end the required Retention Period (as defined below).

To exercise the Repriced Options at the New Exercise Price, Eligible Participants must remain in service with the Company throughout the Retention Period (as defined herein). The retention period begins on the Effective Date and ends on the earlier of (i) the one-year anniversary of the Effective Date, or (ii) a Corporate Transaction (as defined in the 2016 Amended Plan). If the Retention Period is not satisfied, the Eligible Participant will be required to pay the original exercise price of the corresponding option upon exercise. This requirement is waived if the Eligible Participant’s service is terminated due to death or disability (as defined in the 2026 Plan). Additionally, if a Corporate Transaction occurs prior to the first anniversary of the Repricing Date, the exercise price of the Repriced Options will be equal to $2.39 per share.

The repricing was communicated to employees during January 2026. The estimated incremental stock compensation cost of approximately $1.9 million, calculated using a lattice model, will be recognized over the retention period. The Company recognized approximately $0.5 million  and $0.8 million of incremental stock-based compensation expense during the three and six month periods ended June 30, 2026, respectively.

Note 12—Net Loss Per Share Attributable to Common Stockholders

The Company calculates basic and diluted net loss per share attributable to common stockholders in conformity with the two-class method required for participating securities. The Company considers its convertible preferred stock to be participating securities as, in the event a dividend is paid on common stock, the holders of convertible preferred stock and unvested shares of common stock would be entitled to receive dividends on a basis consistent with the common stockholders. The net loss attributable to common stockholders is not allocated to the convertible preferred stock as the holders of those securities do not have a contractual obligation to share in losses. Deemed dividends, if any, on preferred stock are added to net loss to arrive at net loss attributable to common stockholders.

Under the two-class method, basic net loss per share attributable to common stockholders is computed by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock outstanding during the period, without consideration of potential dilutive securities. Diluted net loss per share attributable to common stockholders is calculated by dividing the net loss attributable to common stockholders by the weighted-average number of shares of common stock and potential dilutive common stock equivalents outstanding during the period if the effect is dilutive. During all periods presented, the Company incurred net losses attributable to common stockholders. Accordingly, the effect of any common stock equivalents would have been anti-dilutive during those periods and are not included in the calculation of diluted net loss per share attributable to common stockholders. Included in the weighted-average shares of common stock outstanding for the three months ended June 30, 2026 and 2025 were 428,560 vested shares, respectively, related to a warrant to purchase the Company’s common stock at an exercise price of $0.01 per share (‘‘Penny Warrants’’).

Basic and diluted net loss per share attributable to common stockholders is calculated as follows (in thousands, except share and per share amounts):

		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
Numerator:
Net loss		$	(69,029	)		$	(58,731	)		$	(132,588	)		$	(116,605	)
Denominator:
Weighted-average shares of common stock outstanding – basic and diluted			26,696,158				26,439,086				26,696,158				26,423,995
Net loss per share attributable to common stockholders – basic and diluted		$	(2.59	)		$	(2.22	)		$	(4.97	)		$	(4.41	)

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The following outstanding potentially dilutive securities have been excluded from the calculation of diluted net loss per share, as their effect is anti-dilutive:

		June 30, 2026				December 31, 2025
Convertible preferred stock, common stock equivalent, if converted			213,907,881				213,907,881
Options to purchase common stock			29,244,110				29,512,900
Restricted stock units issued and outstanding			14,262,838				14,472,242
Warrants to purchase common stock			49,500				49,500
Convertible notes			17,208,781				17,170,902
Total			274,673,110				275,113,425

Note 13—Commitment and Contingencies

Legal Contingencies

The Company may be, from time to time, a party to various disputes and claims arising from normal business activities. The Company accrues for loss contingencies when available information indicates that it is probable that a liability has been incurred and the amount of such liability can be reasonably estimated. For cases in which the Company believes that a reasonably possible loss exists, the Company discloses the facts and circumstances of the loss contingency, including an estimable range, if possible. Management believes that there are currently no claims or actions pending against the Company where the ultimate disposition could have a material adverse effect on the Company’s results of operations, financial condition, or cash flows.

Indemnification Agreements

The Company has agreed to indemnify its officers and directors for certain events or occurrences, subject to certain limits, while the officer or director was serving at the Company’s request in such capacity. The maximum amount of potential future indemnification liability is unlimited; however, the Company holds directors’ and officers’ liability insurance which limits the Company’s exposure and may enable it to recover a portion of any future amounts paid.

In the normal course of business, the Company also enters into contracts and agreements with service providers and other parties with which it conducts business that contain indemnification provisions pursuant to which the Company has agreed to indemnify the party against certain types of third-party claims. From time to time, the Company may receive indemnification claims under these contracts in the normal course of business. The Company has not experienced any material losses related to these indemnification provisions and has no material claims with respect thereto. The Company does not expect significant claims related to these indemnification provisions and, consequently, concluded that the fair value of any obligations is negligible, and no related accruals have been established. In the event that one or more of these matters were to result in a claim against the Company, an adverse outcome, including a judgment or settlement, may cause a material adverse effect on the Company’s future business, operating results, or financial condition.

Purchase Commitments

In the normal course of business, the Company enters into agreements containing noncancellable purchase commitments for goods and services with various parties. As of June 30, 2026, the Company has a noncancellable cloud services agreement and has committed to purchase cloud computing services totaling $119.1 million over the remaining period of the agreement through January 31, 2029. Other noncancellable unconditional purchase commitments having a remaining term over one year were as follows (in thousands):

Year Ending December 31,
2026 (remainder of year)		$	4,159
2027			8,250
		$	12,409

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Note 14—Leases

The Company’s lease portfolio consists primarily of operating leases for its current corporate headquarters, laboratory facilities, and warehouse facilities, with lease terms ranging from 1 to 11 years. Certain of the Company’s operating leases contain optional renewal periods to extend the lease terms, which are not reasonably assured. The Company’s operating leases include various covenants, indemnities, defaults, termination rights, security deposits and other provisions customary for lease transactions of this nature.

The Company’s most significant operating lease pertains to an 11-year lease agreement for approximately 335,419 square feet used as its corporate headquarters, office, and laboratory space in two buildings (building I and building III) located in Brisbane, California. The lease will continue for an initial term of 11 years, with options to extend the term for two successive five-year periods after the initial expiration date.

The components of lease costs, were as follows (in thousands):

		Six Months Ended June 30,
		2026				2025
Operating lease cost		$	12,264			$	14,301
Variable lease cost			5,174				5,129
Finance lease cost:
Finance lease amortization			46				92
Interest on finance lease liabilities			—				3
Total lease cost		$	17,484			$	19,525

Certain information related to the Company’s leases was as follows (in thousands):

		Six Months Ended June 30,
		2026				2025
Cash paid for amounts included in the measurement of lease liabilities:
Operating leases		$	13,224			$	15,368
Finance leases		$	—			$	135

		June 30, 2026				June 30, 2025
Weighted-average remaining lease term (in years):
Operating leases			8.5				9.4
Finance leases			—				0.1
Weighted-average discount rate:
Operating leases			11.3	%			11.3	%
Finance leases			—	%			7.5	%

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The following table summarizes the Company’s future principal contractual obligations for lease commitments as of June 30, 2026 (in thousands):

Year Ending December 31,		Operating Leases
2026 (remainder of year)		$	16,030
2027			32,872
2028			33,944
2029			35,053
2030			36,201
Thereafter			165,841
Total undiscounted lease payments			319,941
Less: Imputed interest			(115,711	)
Total lease liabilities			204,230
Less: Current portion of lease liabilities			11,194
Non- current lease liabilities		$	193,036

There is no remaining finance lease obligation as of June 30, 2026.

Note 15—Related Party Transactions

Transactions with Affiliates

The Company considers Roche Holdings, Inc. and its affiliates (the ‘‘Roche Group’’) to be related parties due to the Roche Group’s beneficial ownership in the Company, which exceeded 10% of the voting interests in the Company as of June 30, 2026, and December 31, 2025. The Company has entered into certain agreements with the Roche Group for the purchase or use of equipment, consumable products such as reagents and supplies, and services. In addition, the Company has entered into certain material transfer agreements in which the Company transfers certain samples to the Roche Group for research, testing and evaluation. The Company incurred approximately $0.4 million during the three months ended June 30, 2026 and 2025, respectively, and $1.8 million and $0.7 million during the six months ended June 30, 2026 and 2025, respectively under these agreements, which are recognized as R&D expenses in the consolidated statements of operations. The Company has entered into a Research Service Agreement with a member of the Roche Group, pursuant to which the Company uses its multiomics platform to perform tests and data analysis on samples provided by the Roche Group. The Company did not recognize any service revenue under this agreement for the six months ended June 30, 2026 and 2025, respectively.

In November 2025, the Company entered into the Roche License and Option Agreement with Roche Sequencing and the Roche Promissory Note Agreement with Roche Holdings for which the Company received total proceeds of $75.0 million. As of June 30, 2026, the carrying value of the Roche Convertible Note of $65.5 million was recorded as Convertible Note, related party and the $15.0 million allocated to the Roche License and Option Agreement was recorded as other long-term liabilities on the Company’s condensed consolidated balance sheet. The Company recorded interest expense related to the Roche Convertible Note of $0.9 million and $1.9 million during the three and six months ended June 30, 2026. See Note 7 for further description of the Roche License and Option Agreement with Roche Sequencing and Note 8 for further description of the Roche Convertible Note.

Note 16— Segment and Geographic Information

The Company operates as one operating and reportable segment focused on the development of an early cancer detection platform. The Company’s chief operating decision maker (the ‘‘CODM’’) is its Chief Executive Officer, who uses consolidated net loss (that is also reported on the condensed consolidated statements of operations) as the key measure of segment profit and loss that the CODM uses to allocate resources and assess performance. The CODM does not evaluate operating segment performance using asset information.

The CODM uses consolidated net loss to evaluate the Company’s expenditures from the segment and monitor budget-to-actual results. The CODM also considers budget-to-actual variances and available cash when making decisions about the allocation of resources across the organization. Significant segment expenses within consolidated net loss are cost of services, research and development, general and administrative, and other segment items are interest and investment income, net, interest expense and other income (expense), net, which are separately presented on the Company’s condensed consolidated statements of operations.

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The following table presents information about reported segment revenue by geographic location (in thousands):

		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
United States		$	1,465			$	—			$	5,155			$	—
International			809				1,101				1,341				1,495
Total Revenue		$	2,274			$	1,101			$	6,496			$	1,495

During the year ended June 30, 2026, $5.2 million of the Company’s consolidated revenue is attributable to one customer. As of  June 30, 2026 and December 31, 2025, all of the Company’s long-lived assets and right-of-use assets are located in the United States.

Note 18— Subsequent Events

The Company has evaluated subsequent events through Aug 13 2026, the date these unaudited interim condensed consolidated financial statements were available to be issued.

Business Combination

On December 5, 2025, the Company entered into a Business Combination Agreement with Perceptive Capital Solutions Corp (“PCSC”), a publicly traded special purpose acquisition company, and certain of its subsidiaries. On July 20, 2026, the Company completed the transactions contemplated by the Business Combination Agreement, as amended (the “Business Combination” or the “Closing”).

In connection with the Business Combination, PCSC domesticated from the Cayman Islands to the State of Delaware, changed its name to Freenome, Inc. (“New Freenome”), and adopted a new certificate of incorporation and bylaws. Through a series of merger transactions, the Company became a wholly owned subsidiary of New Freenome.

Upon the Closing, the outstanding shares of the Company’s common stock and preferred stock were converted into an aggregate of 68,065,429 shares of New Freenome common stock based on an exchange ratio of approximately 0.282895. In addition, outstanding options to purchase shares of the Company’s common stock were converted into options to purchase an aggregate of 8,272,601 shares of New Freenome common stock, with the number of underlying shares and exercise prices adjusted based on the exchange ratio. Outstanding restricted stock units of the Company were converted into restricted stock units covering an aggregate of 4,034,512 shares of New Freenome common stock.

Upon the Closing, the $75.0 million outstanding principal amount and $2.5 million of accrued interest under the convertible promissory note issued to Roche Holdings, Inc. were converted into 6,460,616 shares of New Freenome common stock.

In connection with the Closing, New Freenome received aggregate gross proceeds of approximately $310.7 million, including $240.0 million of gross proceeds from a private investment in public equity (“PIPE”) financing that closed concurrently with the Business Combination. After giving effect to transaction costs, New Freenome received net proceeds of approximately $295.5 million. Deferred offering costs recorded on the balance sheet were netted off against the net proceeds from the de-SPAC transaction upon closing.

The Business Combination was accounted for as a reverse recapitalization, with the Company determined to be the accounting acquirer and PCSC treated as the acquired company for financial reporting purposes. Accordingly, the historical financial statements of the Company became the historical financial statements of New Freenome upon the Closing.

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Exhibit 99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF

FINANCIAL CONDITION AND RESULTS OF OPERATIONS

The following discussion and analysis of the financial condition and results of operations of Freenome Inc. (“New Freenome,”, “we,” “us,” and “our”) should be read in conjunction with our unaudited interim condensed consolidated financial statements as of and for the three and six months ended June 30, 2026 and 2025, and the audited consolidated financial statements as of and for the year ended December 31, 2025, and in each case, together with the related notes thereto, included elsewhere in this Current Report on Form 8-K with respect to the unaudited condensed consolidated financial statements or included in the proxy statement/prospectus filed with the SEC on June 17, 2026 incorporated herein by reference with respect to the audited consolidated financial statements only.  The discussion and analysis should also be read together with the pro forma financial information included in this Current Report on Form 8-K in the section titled “Unaudited Pro Forma Condensed Combined Financial Information.”

Forward-Looking Statements

This discussion and analysis contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the “safe harbor” created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as “believe,” “expect,” “may,” “will,” “should,” “would,” “could,” “seek,” “intend,” “plan,” “goal,” “project,” “estimate,” “anticipate” or other comparable terms, but the absence of these words does not mean that a statement is not forward-looking. All statements other than statements of historical facts included in this discussion and analysis regarding our strategies, prospects, expectations, financial condition, operations, costs, plans and objectives are forward-looking statements. Examples of forward-looking statements include, among others, statements we make, express or implied, regarding expected future operating results, including: our growth rate and market opportunity; expectations for development or launching of new or improved products and services and their adoption and impact on patients; insurance reimbursement potential; our strategies, clinical trials, commercialization efforts, positioning, competition, resources, capabilities and expectations for future events or performance; the anticipated benefits of our acquisitions and collaborative and licensing arrangements, including estimated synergies and other financial impacts; our need to raise additional capital to fund our existing operations, develop our platform, commercialize new products or expand our operations; and our expectations regarding financial results, including the expected cash runway. Forward-looking statements are neither historical facts nor assurances of future performance or events. Instead, they are based only on current beliefs, expectations, and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy, and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Actual results, conditions, and events may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause actual results, conditions, and events to differ materially from those indicated in the forward-looking statements include, among others, the following: our ability to support demand for our current and future products, including our ability to meet increased demand and to successfully manage our anticipated growth; our ability to successfully develop and commercialize new products and services and assess potential market opportunities; our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our reliance upon certain suppliers; our ability to retain and hire key personnel; approval and maintenance of adequate reimbursement rates for our products and services within and outside of the U.S.; the amount and nature of competition for our products and services; the effects of any judicial, executive or legislative action affecting us or the healthcare system; changes in government policies, laws, regulations, and staffing; recommendations, guidelines and quality metrics issued by various organizations regarding cancer screening or our products and services; our ability to obtain and maintain regulatory approvals and comply with applicable regulations; our ability to protect and enforce our intellectual property; our success establishing and maintaining collaborative, licensing and supplier arrangements; the results of our validation studies and clinical trials, including the risks that the results of future studies and trials may differ materially from the results of previously completed studies and trials; our ability to manage an international business and our expectations regarding our international expansion and opportunities; the potential effects of changing macroeconomic conditions and geopolitical conflict; the possibility that the anticipated benefits from our business acquisitions or collaborative or licensing arrangements will not be realized in full or at all or may take longer to realize than expected; the possibility that the anticipated benefits from our restructuring and cost reduction initiatives will not be realized in full or at all or may take longer to realize than expected; the outcome of any potential litigation or legal proceedings; our ability to raise the capital necessary to support our operations or meet our payment obligations under our indebtedness; our potential exposure to cybersecurity risks and incidents; and our and our service providers’ ability to maintain compliance with privacy and data security laws. The risks included above are not exhaustive, and we anticipate that subsequent events and developments will cause our assessments to change. You are further cautioned not to place undue reliance upon any such forward-looking statements, which speak only as of the date made. We undertake no obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required under applicable securities laws.

Overview

We are an early cancer detection company developing blood-based screening tests leveraging AI/ML to transform multi-cancer and ultimately multi-disease detection. We founded Freenome with the goal to build an automated, scalable multiomics discovery platform and biologically-informed AI/ML designed to identify the earliest signs of disease. Our common platform is designed to evaluate and integrate multiple analytes (e.g., DNA, RNA and proteins) with differentiated wetlab automation capabilities and high-quality clinical trials to develop accurate tests with the potential to address cancer heterogeneity.

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In July 2026, we announced that the U.S. Food and Drug Administration (“FDA”) approved SimpleScreen™ CRC, a new blood-based screening option for colorectal cancer (“CRC”) in adults 45 and older who are at average risk for the disease. Prior to this, we had no products approved for commercial sale in the United States and had not generated any material revenue to date. We continue to incur significant R&D and other expenses related to our ongoing operations. Our ability to generate product revenue sufficient to achieve profitability, if ever, will depend on the successful commercialization of SimpleScreen CRC and future development of multi-cancer early detection tests.

We are also developing a blood-based lung cancer screening test intended for individuals at elevated risk, including current and former smokers who meet guideline-based eligibility criteria. We plan to introduce the lung cancer test as a laboratory developed test (“LDT”) in the second half of 2026. Based on the Company's recently disclosed SimpleScreen Lung LDT validation data, the initial test launch will include only the assay's protein component. Development of the multiomic test will remain the focus of the in vitro diagnostic program.

The Business Combination

On December 5, 2025, we entered into a Business Combination Agreement with Perceptive Capital Solutions Corp (“PCSC”), a publicly traded special purpose acquisition company, and certain of its subsidiaries. On July 20, 2026, we completed the transactions contemplated by the Business Combination Agreement, as amended on July 20, 2026 (the “Business Combination” or the “Closing”).

In connection with the Business Combination, PCSC domesticated from the Cayman Islands to the State of Delaware, changed its name to Freenome, Inc. (“New Freenome”), and adopted a new certificate of incorporation and bylaws. Through a series of merger transactions, we became a wholly owned subsidiary of New Freenome.

Upon the Closing, the outstanding shares of our common stock and preferred stock were converted into an aggregate of 68,065,429 shares of New Freenome common stock based on an exchange ratio of approximately 0.282895. In addition, outstanding options to purchase shares of our common stock were converted into options to purchase an aggregate of 8,272,601 shares of New Freenome common stock, with the number of underlying shares and exercise prices adjusted based on the exchange ratio. Our outstanding restricted stock units were converted into restricted stock units covering an aggregate of 4,034,512 shares of New Freenome common stock.

We also received aggregate gross proceeds of approximately $310.7 million, including $240.0 million of gross proceeds from a private investment in public equity (“PIPE”) financing that closed concurrently with the Business Combination. After giving effect to transaction costs, we received net proceeds of approximately $295.5 million. Deferred offering costs previously recorded on the balance sheet were reclassified as a reduction of the proceeds from the de-SPAC transaction upon the Closing.

Immediately prior to the Closing, the outstanding principal and accrued interest under the convertible promissory note issued to Roche Holdings, Inc. converted into 6,460,616 shares of New Freenome common stock in accordance with the terms of the note.

The Business Combination was accounted for as a reverse recapitalization, with the Company determined to be the accounting acquirer and PCSC treated as the acquired company for financial reporting purposes. Accordingly, the historical financial statements of the Company became the historical financial statements of New Freenome upon the Closing.

As a result of the Business Combination, Freenome became the successor to an SEC-registered and Nasdaq-listed company. Accordingly, Freenome will need to hire additional personnel and implement procedures and processes to comply with public company regulatory requirements and customary governance practices. Freenome also expects to incur additional recurring annual expenses associated with operating as a public company, including directors' and officers' liability insurance, director compensation, and increased accounting, legal, compliance, and administrative costs, including additional personnel, audit fees, and other professional service fees.

Key Trends, Opportunities and Uncertainties

Since our inception, we have incurred significant operating losses and negative cash flows from our operations. Our primary uses of cash to date have been conducting R&D, acquiring Oncimmune in 2023, raising capital, building infrastructure, developing intellectual property, hiring personnel and providing general and administrative support for these operations. To date, we have funded our operations primarily through private placements of our convertible preferred stock, convertible notes and funds received pursuant to our license agreements. As of June 30, 2026, we had raised aggregate gross proceeds of approximately $1.6 billion from these financings, and had cash, cash equivalents and short-term marketable securities of $102.0 million.

We have incurred operating losses in each year since our inception. Our net losses were $132.6 million for the six months ended June 30, 2026 and $219.3 million for the year ended December 31, 2025. As of June 30, 2026, we had an accumulated deficit of $1.5 billion. We expect our expenses and operating losses will increase as we:

• accelerate the development of our AI/ML-driven multiomics platform that seeks to identify the early biological signals of disease;

• expand our commercial and data infrastructure to support future launch of multiple blood-based cancer detection tests;

• further advance our R&D programs;

• seek to identify additional indications;

• expand commercial and operational personnel;

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• maintain, expand, enforce, defend and protect our intellectual property portfolio and provide reimbursement of third-party expenses related to our patent portfolio; and

• seek regulatory approvals for any future product candidates for which we successfully complete clinical trials.

Our net losses may fluctuate significantly from quarter-to-quarter and year-to-year, depending on the timing of regulatory approvals and R&D activities.

Based on our current operating plans, we believe that our existing cash, cash equivalents, and short-term marketable securities, together with the $295.5 million net proceeds received from the Business Combination and our expected $100.0 million milestone payment from Exact Sciences following FDA approval of SimpleScreen CRC, will be sufficient to fund our operations through 2028. This estimate is based on assumptions that may prove to be incorrect, and we could use our capital resources sooner than expected. Accordingly, we may need to raise additional capital in the future through equity offerings, debt financings, collaborations, licensing arrangements, or other strategic transactions. If additional funding is not available on acceptable terms, or at all, it could adversely affect our business, financial condition, and ability to execute our long-term operating plans.

 Following the FDA approval of our CRC test, we expect to incur significant commercialization expenses related to product sales, marketing, manufacturing, distribution, and other activities necessary to support the commercial launch and ongoing commercialization of the product. Accordingly, until such time as we can generate significant revenue from sales of our product and any product candidates, we expect to finance our cash needs through equity offerings, debt financings or other capital sources, including potential collaborations, licenses, royalty financings and other similar arrangements. See “Liquidity and Capital Resources.” However, we may be unable to raise additional funds or enter into such other arrangements when needed on favorable terms or at all. Our failure to raise capital or enter into such other arrangements when needed would have a negative impact on our financial condition and could force us to delay, limit, reduce or terminate our product development or future commercialization efforts or grant rights to develop and market current or future product candidates that we would otherwise prefer to develop and market ourselves.

Exact Sciences License Agreement

In August 2025, we signed an exclusive license agreement with Exact Sciences to advance the commercialization of our blood-based screening test for colorectal cancer. The terms of the license agreement included a $75.0 million upfront payment, received in November 2025, related to partial consideration for the rights and licenses granted. The agreement also provides for up to $700.0 million in future milestone payments upon the achievement of specified development and regulatory milestones, as well as reimbursement of up to $20.0 million of mutually agreed development costs per year over a three-year period as well as tiered royalties on U.S. sales of CRC blood-based screening test products that may result from the collaboration, including a maximum royalty rate of 10% triggered at a 20% gross margin. During the three months ended June 30, 2026, we received a $17.2 million payment from Exact Sciences related to reimbursement of research and development services that were performed during the period.

In August 2025, we also entered into a Convertible Promissory Note Purchase Agreement with Exact Sciences, pursuant to which we issued a senior unsecured convertible promissory note with an aggregate principal amount of $50.0 million. The convertible note bears interest at 5% per annum and matures in August 2030. Following the closing of the Business Combination, the convertible promissory note will automatically convert into shares of our common stock on the date the volume-weighted average trading price of our common stock exceeds $15.00 per share for 10 consecutive trading days.

Roche License

In November 2025, we signed an exclusive license and option agreement with Roche Sequencing Solutions, Inc. (“Roche Sequencing”). The agreement grants Roche Sequencing both (i) an exclusive option to obtain an exclusive, royalty bearing, sublicensable (subject to certain restrictions) license to certain our intellectual property to exploit kitted assays for cancer screening, including for colorectal cancer and lung cancer, outside the U.S. and (ii) a preferred partner right to negotiate a definitive agreement to offer centralized testing services for cancer screening outside of the U.S.

We may receive up to $100.0 million in future milestone payments, as well as royalties on non-U.S. test sales that range from a low single-digits to mid-teens, depending on sales of the Licensed Products. We may also receive up to $24.0 million in SBX research and development related milestones payments.

In November 2025, we also issued to Roche Holdings, Inc. (“Roche Holdings”) a convertible promissory note with an aggregate principal amount of $75.0 million. The convertible promissory note bore interest at 5% per annum and had a maturity date in May 2027. Upon the Closing, the $75.0 million outstanding principal amount and $2.5 million of accrued interest under the convertible promissory note issued to Roche Holdings, Inc. were converted into 6,460,616 shares of New Freenome common stock.

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Components of Results of Operations

Revenue

We recognize license and collaboration revenue in the United States under our exclusive license agreement with Abbott (formerly Exact Sciences), pursuant to which we granted development, data, and manufacturing licenses.

We also generate revenue from the sale and distribution of EarlyCDT Lung test kits in the United Kingdom and other international markets, royalties on EarlyCDT Lung tests performed, and the sale of EarlyCDT Lung test plates through our U.K.-based subsidiary, Freenome Ltd.

In addition, we generate revenue from diagnostic and research services performed using our proprietary multiomics platform under a Research Services Agreement with a related party.

Following the FDA approval of SimpleScreen CRC, we achieved the first regulatory milestone under our collaboration and license agreement with Abbott, resulting in a $100.0 million milestone payment. We expect to generate additional revenue under this agreement upon the achievement of certain future milestones, as well as royalties on product sales. We may also generate revenue from future collaboration or license agreements for our current or future product candidates and from product sales of any additional approved products. Our ability to generate future revenue will depend on the successful commercialization and market adoption of SimpleScreen CRC, the achievement of additional contractual milestones, the successful development and commercialization of future product candidates, and market acceptance of our products. If we fail to successfully commercialize SimpleScreen CRC or develop and commercialize future product candidates, our ability to generate future revenue and our results of operations and financial condition could be adversely affected.

Operating Expenses

Cost of services

Cost of services reflects the aggregate costs incurred in delivering our products and services and is composed of material and service costs including personnel costs, cost of consumables, kits, contract maintenance, labor, and freight associated with the service and other revenue. Our cost of services will increase with successful commercialization of our products.

Research and Development Expenses

R&D has been, and will continue to be, central to our business model. Our R&D expenses to date have been primarily attributable to the development of our next-generation blood tests for early cancer detection, development of our multiomics platform, and clinical validation of our early colorectal cancer detection test. Our R&D expenses primarily include salaries and benefits, stock-based compensation expenses, direct research and development expenses (testing cost, pre-clinical and clinical trial costs including external R&D expenses incurred under arrangements with third parties), materials, laboratory supplies and equipment, information technology (including cloud computing and data storage, equipment and computer hardware costs, and software related expenses), facility costs (including rent, depreciation and amortization, repairs and maintenance and other facility related expenses), consulting, contractor costs, along with other expenses.

Payments, including non-refundable advance payments, made prior to the receipt of goods or services to be used in R&D activities are deferred and recognized as an expense in the period in which the related goods are received or services are rendered. Costs to develop our technology capabilities are recorded as R&D expenses unless they meet the criteria to be capitalized as internal-use software costs.

Prior to obtaining premarket regulatory approval for our diagnostic tests, we expensed pre-launch inventory costs as research and development ("R&D") expenses unless future economic benefits were considered probable. Accordingly, materials, equipment, and validation costs associated with our diagnostic workflow process that did not have an alternative future use were recognized as R&D expense.

In June 2026, in anticipation of FDA approval of our colorectal cancer screening test, we began capitalizing qualifying inventory costs associated with commercial production as we determined that future economic benefits associated with such costs were expected to be realized. As a result, we capitalized approximately $1.6 million of qualifying raw material costs as inventory. Costs incurred that do not qualify for capitalization, including costs for which no future economic benefit is expected, continue to be recognized as research and development expense.

We accrue and expense clinical and preclinical trial activities performed by third parties based on the actual work completed in accordance with agreements established with our service providers.

We have not historically tracked or recorded R&D expenses on a program-by-program basis and, therefore, have not reported program costs. We do not allocate indirect costs to specific product development programs because these costs support multiple programs and our technology platform and, as such, are not separately classified.

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We expect our R&D expenses to continue to increase as we advance our technology platform, support additional product development activities, and conduct future clinical studies.

The timing and costs of our R&D activities remain uncertain and may vary significantly due to the inherently unpredictable nature of product development and clinical research. We expect to continue evaluating our development priorities and allocating resources among our programs based on preclinical and clinical results, regulatory developments, and our ongoing assessment of each program's commercial potential.

Our future development costs may vary significantly based on various factors such as timely and successful completion of preclinical studies and ongoing and future clinical trials, positive results from our current and future clinical trials, receipt of marketing approvals from applicable regulatory authorities, establishment and maintenance of arrangements with third parties, intellectual property updates and continued acceptable safety, tolerability and efficacy profile of any current and future product candidates that we may develop following approval.

General and Administrative Expenses

Our general and administrative (“G&A”) expenses primarily consist of costs for our executive, accounting and finance, legal, human resources, marketing, and other administrative support functions. These expenses consist principally of personnel costs, including salaries, bonuses, fringe benefits, stock-based compensation expenses, and travel expenses, as well as professional services fees such as consulting, audit, tax, and legal fees, and general corporate costs and allocated overhead expenses.

We anticipate that our G&A expenses will increase in future periods as we incur additional costs to support the growth of our business and expand our infrastructure, and as a result of commercialization activities if any additional diagnostic test candidates of ours receive marketing approval. We also anticipate increased expenses related to accounting, audit, legal, regulatory, and tax-related services, costs associated with maintaining compliance with the Nasdaq Global Market (“Nasdaq”) and SEC requirements, director and officer insurance premiums, investor relations and other costs associated with operating as a public company.

Other Income (Expense), Net

Other income (expense), net consists primarily of interest earned on our short-term investments and marketable securities and interest incurred on our convertible notes.

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Comparison of the Three and Six Months Ended June 30, 2026 and 2025

The following table summarizes the results of our operations for the periods indicated (in thousands):

		Three Months Ended June 30,								Six Months Ended June 30,
		2026				2025				2026				2025
Revenue:
License and collaboration revenue		$	1,465			$	—			$	5,155			$	—
Service and other revenue			809				1,101				1,341				1,495
Total revenue		$	2,274			$	1,101			$	6,496			$	1,495
Operating costs and expenses:
Cost of services		$	497				509				937				884
Research and development			54,273				48,936				106,387				98,653
General and administrative			12,711				11,845				26,624				22,220
Total operating costs and expenses			67,481				61,290				133,948				121,757
Loss from operations			(65,207	)			(60,189	)			(127,452	)			(120,262	)
Other income (expense), net:
Interest and investment income, net		$	1,038				1,514				2,729				3,717
Interest expense			(4,859	)			(1	)			(7,863	)			(3	)
Other (expense), net			(1	)			(55	)			(2	)			(57	)
Net loss		$	(69,029	)		$	(58,731	)		$	(132,588	)		$	(116,605	)

Revenue

The following table summarizes our revenues for the following periods (in thousands):

		Three Months Ended June 30,												Six Months Ended June 30,
		2026				2025				Change				2026				2025				Change
Revenue:
License and collaboration revenue		$	1,465			$	—			$	1,465			$	5,155			$	—			$	5,155
Service and other revenue			809				1,101				(292	)			1,341				1,495				(154	)
Total revenue		$	2,274			$	1,101			$	1,173			$	6,496			$	1,495			$	5,001

Revenue increased by $1.2 million to $2.3 million for the three months ended June 30, 2026, compared to $1.1 million for the three months ended June 30, 2025. The increase was primarily driven by $1.5 million of license and collaboration revenue recognized under the Exact Sciences License and Collaboration Agreement related to initial technology transfer activities and research and development services performed during the three months ended June 30, 2026.

Revenue for the three months ended June 30, 2026 also included $0.3 million from the sale and distribution of EarlyCDT Lung test kits in the United Kingdom and other international markets, $0.4 million of royalties on EarlyCDT Lung tests performed, and $0.1 million from the sale of EarlyCDT Lung test plates.

Revenue increased by $5.0 million, to $6.5 million for the six months ended June 30, 2026, from $1.5 million for the six months ended June 30, 2025. The increase was primarily attributable to $5.2 million of license and collaboration revenue recognized under the Exact Sciences License and Collaboration Agreement related to initial technology transfer activities and for research and development services performed during the six months ended June 30, 2026.

Revenue for the six months ended June 30, 2026 also included $0.4 million from the sale and distribution of EarlyCDT Lung test kits in the United Kingdom and other international markets, $0.8 million of royalties on EarlyCDT Lung tests performed, and $0.2 million from the sale of EarlyCDT Lung test plates.

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Cost of services

The following table summarizes our cost of services for the following periods (in thousands):

		Three Months Ended June 30,												Six Months Ended June 30,
		2026				2025				Change				2026				2025				Change
Cost of services		$	497			$	509			$	(12	)		$	937			$	884			$	53

The decrease in cost of services for the three and six months ended June 30, 2026, compared to the corresponding periods in 2025, was not material.

Research and Development Expenses

The following table summarizes our research and development expenses for the following periods (in thousands):

		Three Months Ended June 30,								Change				Change
		2026				2025				$					%
Salaries and benefits		$	18,844			$	17,422			$	1,422				8	%
Facility, depreciation and amortization			15,414				15,977				(563	)			(4	)%
Materials, laboratory supplies and equipment			11,716				4,816				6,900				143	%
Information technology			3,163				3,115				48				2	%
Direct research and development costs			2,288				3,014				(726	)			(24	)%
Stock-based compensation			1,277				1,382				(105	)			(8	)%
Consulting and contractor			1,272				1,004				268				27	%
Other			299				327				(28	)			(9	)%
		$	54,273			$	47,057			$	7,216				15	%

Research and development expenses increased by $7.2 million, from $47.1 million for the three months ended June 30, 2025, to $54.3 million for the three months ended June 30, 2026.

The increase was primarily attributable to:

• $6.9 million increase in materials, laboratory supplies and equipment expenses, mainly due to increased raw material purchases associated with the commencement of Early Access Program (“EAP”) testing in early 2026 to operationalize the end-to-end commercial workflow for the CRC test, as well as increased spending on development projects;

• $1.3 million increase in personnel-related expenses, including salaries, benefits and stock-based compensation, primarily driven by higher salaries, bonus expense and other payroll-related costs resulting from additional corporate employees, partially offset by a decrease in stock-based compensation.

• $0.3 million increase in consulting and contractor expenses; and

• $48,000 increase in information technology expenses.

The increase was partially offset by:

• $0.7 million decrease in direct research and development expenses, primarily due to reduction in clinical trial costs;

• $0.6 million decrease in facility, depreciation and amortization expenses, primarily due to lower facilities-related costs, partially offset by increased amortization of leasehold improvements associated with our laboratory facilities; and

• $28,000 decrease in other expenses.

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The following table summarizes our research and development expenses for the following periods (in thousands):

		Six Months Ended June 30,								Change				Change
		2026				2025				$					%
Salaries and benefits		$	36,616			$	35,424			$	1,192				3	%
Facility, depreciation and amortization			30,676				31,446				(770	)			(2	)%
Materials, laboratory supplies and equipment			23,865				9,677				14,188				147	%
Information technology			5,910				5,967				(57	)			(1	)%
Direct research and development costs			4,113				6,717				(2,604	)			(39	)%
Stock-based compensation			2,600				2,701				(101	)			(4	)%
Consulting and contractor			2,054				2,252				(198	)			(9	)%
Other			553				681				(128	)			(19	)%
		$	106,387			$	94,865			$	11,522				12	%

Research and development expenses increased by $11.5 million, from $94.9 million for the six months ended June 30, 2025, to $106.4 million for the six months ended June 30, 2026.

The increase was primarily attributable to:

• $14.2 million increase in materials, laboratory supplies and equipment expenses, mainly due to increased raw material purchases associated with the commencement of EAP testing in early 2026 to operationalize the end-to-end commercial workflow for the CRC test, as well as increased spending on development projects; and

• $1.1 million increase in personnel-related expenses, including salaries, benefits and stock-based compensation, primarily driven by higher salaries, bonus expense and other payroll-related costs resulting from additional corporate employees, partially offset by a decrease in stock-based compensation.

The increase was partially offset by:

• $2.6 million decrease in direct research and development expenses, primarily due to lower clinical trial costs;

• $0.8 million decrease in facility, depreciation and amortization expenses, primarily due to lower facilities-related costs, partially offset by increased amortization of leasehold improvements associated with our laboratory facilities;

• $0.2 million decrease in consulting and contractor expenses;

• $0.1 million decrease in other expenses; and

• $57,000 decrease in information technology expenses.

General and Administrative Expenses

The following table summarizes our general and administrative expenses for the following periods (in thousands):

		Three Months Ended June 30,								Change				Change
		2026				2025				$					%
Salaries and benefits		$	6,446			$	6,448			$	(2	)			—	%
Consulting and contractor			2,311				3,805				(1,494	)			(39	)%
Stock-based compensation			1,457				1,356				101				7	%
Information technology			1,368				1,109				259				23	%
Facility, depreciation and amortization			629				651				(22	)			(3	)%
Other			500				354				146				41	%
		$	12,711			$	13,723			$	(1,012	)			(7	)%

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General and administrative ("G&A") expenses decreased by $1.0 million, from $13.7 million for the three months ended June 30, 2025, to $12.7 million for the three months ended June 30, 2026.

The decrease in G&A expenses was primarily attributable to:

• $1.5 million decrease in consulting and contractor expenses; and

• $22,000 decrease in facilities, depreciation and amortization expenses, primarily related to our office facilities.

The decrease was partially offset by:

• $0.1 million increase in personnel-related expenses, including salaries, benefits and stock-based compensation, primarily driven by higher stock-based compensation expense;

• $0.3 million increase in information technology-related software expenses; and

• $0.1 million increase in other expenses.

The following table summarizes our general and administrative expenses for the following periods (in thousands):

		Six Months Ended June 30,								Change				Change
		2026				2025				$					%
Salaries and benefits		$	12,613			$	12,703			$	(90	)			(1	)%
Consulting and contractor			5,924				6,943				(1,019	)			(15	)%
Stock-based compensation			3,036				2,313				723				31	%
Information technology			2,868				2,138				730				34	%
Facility, depreciation and amortization			1,312				1,205				107				9	%
Other			871				706				165				23	%
		$	26,624			$	26,008			$	616				2	%

General and administrative (“G&A”) expenses increased by $0.6 million, from $26.0 million for the six months ended June 30, 2025, to $26.6 million for the six months ended June 30, 2026.

The increase was primarily attributable to:

• $0.7 million increase in information technology-related software expenses;

• $0.6 million increase in personnel-related expenses, including salaries, benefits and stock-based compensation, primarily driven by higher stock-based compensation expense associated with the addition of C-suite executives, partially offset by lower salary expense resulting from an overall reduction in headcount compared with the same period in the prior year;

• $0.2 million increase in facilities, depreciation and amortization expenses related to our office buildings; and

• $0.1 million increase in other expenses.

These increases were partially offset by a $1.0 million decrease in consulting and contractor expenses.

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Other income (expense), net

The following table summarizes our Other income (expense), net, for the following periods (in thousands):

		Three Months Ended June 30,												Six Months Ended June 30,
		2026				2025				Change				2026				2025				Change
Other income (expense), net:
Interest and investment income, net		$	1,038			$	1,514			$	(476	)		$	2,729			$	3,717			$	(988	)
Interest expense			(4,859	)			(1	)			(4,858	)			(7,863	)			(3	)			(7,860	)
Other (expense), net			(1	)			(55	)			54				(2	)			(57	)			55
Total other income (expense), net:		$	(3,822	)		$	1,458			$	(5,280	)		$	(5,136	)		$	3,657			$	(8,793	)

Interest and Investment Income, Net

Interest and investment income, net, decreased by $0.5 million, from $1.5 million for the three months ended June 30, 2025, to $1.0 million for the three months ended June 30, 2026. Interest and investment income, net, decreased by $1.0 million, from $3.7 million for the six months ended June 30, 2025, to $2.7 million for the six months ended June 30, 2026. The decreases were primarily attributable to lower interest income resulting from reduced balances of short-term investments and marketable securities.

Interest expense

The increase in interest expense for the three and six months ended June 30, 2026, as compared to the three and six months ended June 30, 2025 is primarily attributable to interest expense and amortization of the debt discount related to the Roche convertible promissory note, as well as interest expense associated with the Exact Sciences convertible promissory note.

Cash Flows

Comparison of the Six Months Ended June 30, 2026 and 2025

The following table summarizes our cash flows during the periods indicated (in thousands):

		Six Months Ended June 30,								Change
		2026				2025					$
Net cash flows used in operating activities		$	(97,110	)		$	(99,646	)		$	2,536
Net cash flows provided by investing activities			110,665				92,744				17,921
Net cash flows used in financing activities			(6,185	)			(31	)			(6,154	)

Operating Activities

For the six months ended June 30, 2026, net cash used in operating activities was $97.1 million, primarily attributable to our net loss of $132.6 million, partially offset by non-cash charges of $24.1 million and $11.4 million of net cash provided by changes in operating assets and liabilities. Non-cash charges primarily included depreciation and amortization, stock-based compensation expense, non-cash interest expense and amortization of debt issuance costs, and amortization of right-of-use assets, partially offset by net accretion and amortization of investments in marketable securities and changes in the fair value of convertible notes. The $11.4 million of net cash provided by changes in operating assets and liabilities primarily reflected an increase of $14.8 million in deferred revenue, an increase of $7.8 million in accounts payable, and a decrease of $2.2 million in accounts and other receivables, partially offset by a decrease of $4.4 million in accrued compensation and other related benefits, a decrease of $4.9 million in operating lease liabilities, a decrease of $0.5 million in accrued expenses and other current liabilities, and an increase of $0.8 million in prepaid expenses and other current assets.

For the six months ended June 30, 2025, net cash used in operating activities was $99.6 million, primarily attributable to our net loss of $116.6 million and $0.5 million of net cash used by changes in operating assets and liabilities, partially offset by non-cash charges of $17.5 million. Non-cash charges primarily included depreciation and amortization, stock-based compensation expense, and amortization of right-of-use assets, partially offset by net accretion and amortization of investments in marketable securities. The $0.5 million of net cash used by changes in operating assets and liabilities primarily reflected decreases of $5.1 million in accrued compensation and other related benefits, a decrease of $1.8 million in accounts payable, and a decrease of $1.2 million in prepaid expenses and other current assets. These changes were partially offset by increases of $0.3 million in accounts and other receivables, an increase of $0.3 million in other long-term assets, and an increase of $7.0 million in operating lease liabilities.

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Investing Activities

Net cash provided by investing activities was $110.7 million during the six months ended June 30, 2026, and consisted primarily of the net proceeds from maturity and purchase of marketable securities of $123.2 million, offset by $12.5 million used for the purchase of property and equipment.

Net cash provided by investing activities was $92.7 million during the six months ended June 30, 2025, and consisted primarily of the net proceeds from maturity and purchase of marketable securities of $110.3 million, offset by $17.6 million used for the purchase of property and equipment.

Financing Activities

Net cash used in financing activities was $6.2 million during the six months ended June 30, 2026 and consisted primarily of offering costs paid.

Net cash used in financing activities was $31,000 during the six months ended June 30, 2025 and consisted primarily of payments made on financing leases, offset by proceeds received from the exercise of stock options.

Liquidity and Capital Resources

Sources of Liquidity

We have historically financed our operations primarily through the sale of equity securities and the issuance of convertible notes and, to a lesser extent, upfront payments received under licensing arrangements. As of June 30, 2026, we had cash, cash equivalents, and marketable securities of $102.0 million. As of June 30, 2026, the aggregate principal amount outstanding under our convertible notes was $107.2 million. In connection with the closing of the Business Combination, approximately $77.5 million of principal and accrued interest outstanding under the Roche Convertible Note was automatically converted into shares of New Freenome common stock.

Since our inception, we have incurred significant operating losses and negative cash flows from operations. During the six months ended June 30, 2026, we incurred a net loss of $132.6 million, used $97.1 million of cash in operating activities, and had an accumulated deficit of $1.5 billion.

Since inception, we have received aggregate gross proceeds of approximately $1.6 billion from the sale of convertible preferred stock in private placements, the issuance of convertible notes, and upfront payments and cost-sharing arrangements under our strategic collaborations. As described above, upon closing of the Business Combination, we received aggregate gross proceeds of $310.7 million, including $240.0 million in gross proceeds from a PIPE financing. After giving effect to transaction costs, New Freenome received net proceeds of approximately $295.5 million.

As discussed above, in August 2025, we entered into an exclusive license agreement with Exact Sciences to advance the commercialization of our blood-based colorectal cancer screening test. Under the terms of the agreement, we received $75.0 million upfront payment in partial consideration for the rights and licenses granted and are eligible to receive up to $700.0 million upon the achievement of specified development and regulatory milestones. Following the FDA approval of our SimpleScreen CRC test in July 2026, we will receive $100.0 million milestone payment under the agreement. We are also eligible to receive reimbursement of up to $20.0 million per year for mutually agreed development costs over a three-year period.

Also as discussed above, in November 2025, we entered into an exclusive license and option agreement with Roche Sequencing. Under the agreement, we are eligible to receive up to $100.0 million in milestone payments, as well as royalties on non-U.S. sales of licensed products ranging from the low single digits to the mid-teens, depending on sales levels. We are also eligible to receive up to $24.0 million in future milestone payments related to SBX research and development milestones.

Future Funding Requirements

As of June 30, 2026, we had cash, cash equivalents, and short-term marketable securities of $102.0 million. Based on our current operating plan, we believe that our cash, cash equivalents, and short-term marketable securities as of June 30, 2026, together with the net proceeds from the Business Combination with PSCS described above and the $100.0 million regulatory milestone payment earned following the FDA approval of SimpleScreen CRC under our collaboration and license agreement with Abbott (formerly Exact Sciences), will be sufficient to fund our operations through 2028. This estimate is a forward-looking statement that involves risks and uncertainties, and actual results could differ materially. In addition, the process of commercializing our approved products, conducting preclinical studies and clinical trials, and developing future product candidates is costly, and the timing and extent of related expenditures are uncertain. Accordingly, we may need to raise additional capital in the future.

Our future capital requirements will depend on many factors, including:

• the type, number, scope, progress, timing, results, and costs of our discovery activities, preclinical studies, and clinical trials for our current and future products and product candidates;

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• the costs, timing, and outcome of regulatory review of our current and future product pipeline;

• the timing and terms of establishing and maintaining license, collaboration, and other strategic arrangements;

• the costs of obtaining, maintaining, defending, and enforcing our patents and other intellectual property rights;

• our efforts to enhance our operational infrastructure and hire additional personnel to support our obligations as a public company;

• the costs associated with expanding our workforce and engaging consultants as our development and commercialization activities increase;

• the costs and timing of establishing or expanding sales and marketing capabilities for approved products;

• our ability to achieve market acceptance, obtain coverage and adequate reimbursement from third-party payers, and generate sufficient market share and revenue from approved products; and

• the costs associated with acquiring or licensing additional products, technologies, or intellectual property.

Although we have completed the Business Combination and received the related proceeds, and our SimpleScreen CRC test has received FDA approval, we expect to continue to require substantial capital to support the commercialization of our approved product, advance our research and development programs, pursue additional regulatory approvals, expand our commercial infrastructure, and fund our operations. We may seek to finance our future cash needs through equity offerings, debt financings, or other capital sources, including license agreements, royalty financings, collaborations, and other strategic arrangements.

However, we may be unable to raise additional funds or enter into such arrangements when needed on favorable terms, or at all. To the extent that we raise additional capital through the sale of equity or convertible debt securities, the ownership interests of our stockholders may be diluted, and the terms of these securities could include liquidation or other preferences that adversely affect the rights of our common stockholders. Debt and equity financings, if available, may also involve agreements that include covenants restricting our ability to incur additional indebtedness, make capital expenditures, or take other actions.

If we raise additional capital through license agreements, collaborations, or other strategic arrangements with third parties, we may be required to relinquish valuable rights to our technologies, future revenue streams, research programs, approved products, or future product candidates, or grant licenses on terms that may not be favorable to us. Our inability to obtain additional funding or enter into such arrangements when needed could adversely affect our financial condition and our ability to execute our business strategy. If additional capital is unavailable when required, we may be forced to delay, limit, or reduce investments in commercialization activities, research and development programs, or future product development initiatives.

Contractual Obligations and Commitments

Convertible Notes

As described above, the $50.0 million convertible promissory note issued to Exact Sciences matures in August 2030. Following the Closing of the Business Combination, the note will automatically convert into shares of our common stock on the date on which the volume-weighted average trading price of our common stock exceeds $15.00 per share for 10 consecutive trading days (the “Exact Automatic Conversion Date”). The note is also convertible at the option of Exact Sciences under certain circumstances specified in the note agreement. At a conversion price of $15.00 per share, the note would convert into approximately 3,342,294 shares of our common stock.

As described above, the $75 million convertible promissory note agreement with Roche Holdings automatically converted into 6,460,616 shares of New Freenome common stock upon the closing of the Business Combination in July 2026.

Leases

Our lease portfolio consists primarily of operating leases for our current corporate headquarters, laboratory facilities, and warehouse facilities, with lease terms ranging from 1 to 11 years. Under the terms of the leases, as of June 30, 2026, our lease obligations consist of $320.0 million in payments through March 31, 2035.

Purchase Commitments

As of June 30, 2026, we have entered into a non-cancellable cloud services agreement and committed to purchase cloud computing services totaling $119.1 million through January 31, 2029.

Our other non-cancellable unconditional purchase commitments with a remaining term over one year were $12.4 million as of June 30, 2026.

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License and Collaboration Agreements

See Notes 6 and 7 to the accompanying unaudited condensed consolidated financial statements for a detailed description of our license and collaboration agreements.

Critical Accounting Policies and Estimates

Our management’s discussion and analysis of our financial condition and results of operations are based on our condensed consolidated financial statements, which are prepared in accordance with GAAP. The preparation of our condensed consolidated financial statements requires us to make estimates and assumptions that affect the reported amounts of assets, liabilities, costs and expenses and the disclosure of contingent assets and liabilities in our consolidated financial statements and accompanying notes. We base our estimates and assumptions on historical experience and other factors that we believe to be reasonable under the circumstances. We evaluate our estimates and judgments on an ongoing basis. We base our estimates on historical experience, known trends and events and various other factors that we believe are reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Our actual results may differ from these estimates under different assumptions or conditions.

Our significant accounting policies are more fully described in Note 2, "Summary of Significant Accounting Policies," to the audited consolidated financial statements and related notes included elsewhere in this Current Report on Form 8-K. During the three and six months ended June 30, 2026, there were no material changes to our critical accounting policies from those disclosed previously.

Recent Accounting Pronouncements

See Note 1, Organization and Summary of Significant Accounting Policies, to our condensed consolidated financial statements included elsewhere in this Current Report.

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Exhibit 99.3

UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL INFORMATION

Defined terms included below have the same meaning as terms defined and included in the Current Report on Form 8-K  filed with the Securities and Exchange Commission (the “SEC”) on July 24, 2026 (the “Original Report”) and included elsewhere in this Current Report on Form 8-K/A (“Amendment No. 1”). Unless the context otherwise requires,“Freenome” refers to Freenome Holdings, Inc. prior to the Closing and the “Company” refers to Freenome, Inc. (“New Freenome”) (f/k/a Perceptive Capital Solutions Corp.) and its subsidiaries after the Closing, and Perceptive Capital Solutions Corp. (“PCSC”) prior to the Closing.

Introduction

The following unaudited pro forma condensed combined financial information presents the combination of the financial information of Freenome and PCSC adjusted to give effect to the Business Combination. The following unaudited pro forma condensed combined financial information has been prepared in accordance with Article 11 of Regulation S-X.

The unaudited pro forma condensed combined balance sheet as of June 30, 2026 (the “Unaudited Pro Forma Condensed Combined Balance Sheet”) combines the unaudited condensed consolidated balance sheet of Freenome as of June 30, 2026 and the unaudited condensed consolidated balance sheet of PCSC on a pro forma basis as if the Business Combination had been consummated on June 30, 2026. The unaudited pro forma condensed combined statements of operations for the six months ended June 30, 2026 and year ended December 31, 2025 (the “Unaudited Pro Forma Condensed Combined Statements of Operations”) combines the unaudited condensed consolidated statements of operations of Freenome for the six months ended June 30, 2026, and the unaudited condensed consolidated statements of operations of PCSC for the six months ended June 30, 2026 on a pro forma basis and the audited consolidated statements of operations of Freenome for the year ended December 31, 2025, and the audited consolidated statement of operations of PCSC for the year ended December 31, 2025 on a pro forma basis as if the Business Combination had been consummated on January 1, 2025, the beginning of the earliest period presented. The Unaudited Pro Forma Condensed Combined Balance Sheet as of June 30, 2026 and the Unaudited Pro Forma Condensed Combined Statements of Operations for the six months ended June 30, 2026 and year ended December 31, 2025, together with the accompanying notes, are referenced herein as the “Unaudited Pro Forma Condensed Combined Financial Statements”.

The unaudited pro forma condensed combined financial information has been presented for illustrative purposes only and is not necessarily indicative of the financial position and operating results that would have been achieved had the Business Combination occurred on the dates indicated. The unaudited pro forma condensed combined financial information does not purport to project the future financial position or operating results of New Freenome following the completion of the Business Combination and may not be useful in predicting the future financial condition and results of operations of New Freenome following the Closing. The actual financial position and results of operations may differ significantly from the pro forma amounts reflected in this Current Report on Form 8-K/A due to a variety of factors. Assumptions and estimates underlying the unaudited pro forma adjustments included in the unaudited pro forma condensed combined financial information are described in the accompanying notes. The unaudited pro forma adjustments represent management’s estimates based on information available as of the date on which this unaudited pro forma condensed combined financial information is prepared and are subject to change as additional information becomes available and analyses are performed.

The unaudited pro forma condensed combined financial information was derived from and should be read together with the accompanying notes to the unaudited pro forma condensed combined financial information and the followings:

• Freenome’s unaudited condensed consolidated financial statements as of June 30, 2026 and for the three and six months ended June 30, 2026 and 2025 included as Exhibit 99.1 in this Amendment No. 1;

• Freenome’s Management’s Discussion and Analysis of Financial Condition and Results of Operations  for the three and six months ended June 30, 2026 and 2025 included as Exhibit 99.2 in this Amendment No. 1;

• PCSC’s unaudited condensed consolidated financial statements as of and for the three and six months ended June 30, 2026 and 2025 as filed with the SEC on Form 10-Q on July 15, 2026;

• the financial statements of Freenome and PCSC included in the Proxy Statement/Prospectus;

• the sections titled “Freenome’s Management’s Discussion and Analysis of Financial Condition and Results of Operations” and “PCSC’s Management’s Discussion and Analysis of Financial Condition and Results of Operations,” and other information relating to Freenome and PCSC contained in the Proxy Statement/Prospectus, including the Business Combination Agreement and the description of certain terms thereof set forth in the section titled “The Business Combination.”

Description of the Business Combination

On the Closing Date, PCSC consummated the previously announced business combination pursuant to the terms of the Business Combination Agreement with Merger Sub I, Merger Sub II, and Freenome. Pursuant to the terms of the Business Combination Agreement, among other things, the following occurred: (1) the Domestication; (2) the Mergers; and (3) the consummation of the other transactions contemplated by the Business Combination Agreement and documents related thereto (such transactions, together with the Domestication and the Mergers, the “Business Combination”). In connection with the consummation of the Business Combination, PCSC changed its corporate name to Freenome, Inc. (“New Freenome”).

In accordance with the terms and subject to the conditions of the Business Combination Agreement, at the effective time of the First Merger:

• each share of Freenome’s capital stock that was issued and outstanding as of immediately prior to the Merger Effective Time (excluding treasury shares and dissenting shares) was automatically cancelled and converted into the right to receive a corresponding number of shares of New Freenome Common Stock, equal to the Exchange Ratio of approximately 0.282895;

• each outstanding and unexercised Freenome Option became a New Freenome Option containing the same terms, conditions, vesting and other provisions as were applicable to such Freenome Options, provided that each New Freenome Option is exercisable for the number of shares of New Freenome Common Stock equal to the Exchange Ratio multiplied by the number of shares of Freenome common stock subject to the Freenome Option as of immediately prior to the Merger Effective Time, rounded down to the nearest whole share, at an exercise price equal to the per share exercise price of the Freenome Option divided by the Exchange Ratio, rounded up to the nearest whole cent;

• each outstanding and unexercised Freenome Warrant became a warrant of New Freenome containing the same terms, conditions, vesting and other provisions as were applicable to such Freenome Warrant, as adjusted for the Exchange Ratio.

In addition, on the Closing Date, the PIPE Investors purchased from New Freenome an aggregate of 24,000,000 shares of New Freenome Common Stock, for a purchase price of $10.00 per share and aggregate proceeds of $240.0 million, pursuant to the Subscription Agreements.

Accounting Treatment of the Business Combination

The Business Combination was accounted for as a reverse recapitalization in accordance with U.S. GAAP, whereby PCSC was treated as the acquired company and Freenome was treated as the accounting acquirer. Accordingly, for accounting purposes, the Business Combination was treated as the equivalent of Freenome issuing stock for the net assets of PCSC, accompanied by a recapitalization. The net assets of PCSC are recorded at their historical amounts, which approximated fair value, with no goodwill or other intangible assets recorded. Subsequently, results of operations presented for the periods prior to the Business Combination are those of Freenome.

Freenome was determined to be the accounting acquirer in the Business Combination based on the following predominate factors:

• Freenome’s existing shareholders have the greatest voting interest in the combined entity with approximately 63% of the voting interest;

• Freenome has the ability to designate a majority of the initial members of New Freenome’s Board;

• Freenome’s senior management is the senior management of the combined entity;

• Freenome is the larger entity based on historical operating activity and has the larger employee base; and

• The post-combined company assumed a Freenome branded name: “Freenome, Inc.”

Basis of Pro Forma Presentation

The unaudited pro forma condensed combined financial information has been prepared in accordance with Article 11 of Regulation S-X. Management has made significant estimates and assumptions in its determination of the pro forma adjustments based on information available as of the date of this Amendment No. 1. As the unaudited pro forma condensed combined financial information has been prepared based on these preliminary estimates, the final amounts recorded may differ materially from the information presented as additional information becomes available. Management considers this basis of presentation to be reasonable under the circumstances.

In accordance with PCSC’s governing documents, upon the Extension Amendment and upon closing of the Business Combination, PCSC provided the holders of PCSC Class A Shares the right to have all or a portion of their PCSC Class A Shares redeemed for cash, for a per-share price equal to the pro rata portion of the funds then in PCSC’s trust account (including interest not previously released to pay taxes). The unaudited condensed combined pro forma financial statements reflect actual redemptions of 2,146,731 PCSC Class A Shares, of which 754,008 PCSC Class A Shares were redeemed at approximately $10.82 per share, or $8.2 million in the aggregate in connection with the Extension Amendment Proposal and 1,392,723 PCSC Class A Shares were redeemed at approximately $10.86 per share, or $15.1 million in the aggregate in connection with the Closing.

The unaudited pro forma condensed combined financial information gives effect to the Business Combination and related transactions, including:

• The PIPE Investment;

• The conversion of Roche Convertible Note (including principal and accrued interest) into shares of New Freenome Common Stock;

• Incremental compensation expense associated with the grant of Anti-Dilution Equity Awards and vested restricted stock units;

• The conversion of each issued and outstanding PCSC Class A Share and PCSC Class B Share and each outstanding preference share of PCSC (if any) into New Freenome Common Stock; and

• The issuance of New Freenome Common Stock in connection with the Mergers.

The following summarizes the pro forma capitalization of the post-combination company immediately following the Closing:

		Number of Shares				%
Freenome equity holders (1)			68,065,429				63.4	%
PCSC’s public stockholders (2)			6,478,269				6.0	%
Holders of PCSC’s sponsor shares (3)			2,442,500				2.3	%
PIPE Investors (4)			24,000,000				22.3	%
Roche convertible note			6,460,616				6.0	%
Pro Forma Common Stock Outstanding			107,446,814				100.0	%

(1) Amount excludes 2,833,838 Freenome restricted stock units that will vest following the Closing. Includes 5,371,847 shares of New Freenome Common Stock issued to the Perceptive PIPE Investor upon conversion of Freenome capital stock.

(2) Reflects 7,870,992 PCSC Class A Shares outstanding as of June 30, 2026, less 1,392,723 PCSC Class A Shares redeemed in connection with the Closing.

(3) Includes 2,066,250 PCSC Class B Shares and 286,250 PCSC Class A private placement shares held by the Sponsor and 90,000 PCSC Class B Shares held by PCSC independent directors.

(4) Includes 5,500,000 PIPE Shares issued to the Perceptive PIPE Investor, 5,255,376 PIPE Shares issued to a Freenome equity holder and 13,244,624 PIPE Shares issued to third-party PIPE Investors.

UNAUDITED PRO FORMA CONDENSED COMBINED BALANCE SHEET

AS OF JUNE 30, 2026

(in thousands)

		Freenome (Historical)				PCSC (Historical)				Transaction Accounting Adjustments (Note 2)					Pro Forma Combined
Assets
Cash and cash equivalents		$	85,467			$	437			$	69,967		(b)		$	377,344
											(3,450	)	(c)
											240,000		(d)
											(15,077	)	(h)
Short-term marketable securities			16,557				-									16,557
Accounts and other receivables			3,547				-									3,547
Prepaid expenses and other current assets			7,695				305									8,000
Total current assets			113,266				742				291,440					405,448
Cash and investments held in Trust Account			-				85,086				(15,119	)	(a)			-
											(69,967	)	(b)
Property and equipment, net			156,961				-									156,961
Operating lease right-of-use asset, net			95,806				-									95,806
Intangible assets, net			2,758				-									2,758
Goodwill			10,513				-									10,513
Other long-term assets			9,635				-				(9,357	)	(h)			278
Restricted cash			9,560				-									9,560
Total assets		$	398,499			$	85,828			$	196,997				$	681,324
Liabilities
Accounts payable		$	12,852			$	-				(1,392	)	(h)		$	11,460
Accrued compensation and other related benefits			8,991				-									8,991
Accrued expenses and other current liabilities			3,390				3,628				(4,463	)	(h)			2,555
Deferred revenue			71,106				-									71,106
Current portion of lease liabilities			11,194				-									11,194
Total current liabilities			107,533				3,628				(5,855	)				105,306
Lease liabilities, net of current portion			193,036				-									193,036
Convertible note, at fair value			41,700				-									41,700
Convertible note, related party			65,523								(65,523	)	(i)			-
Deferred revenue, net of current portion			-													-
Other long-term liabilities			17,318													17,318
Deferred underwriting compensation			-				3,450				(3,450	)	(c)			-
Total liabilities			425,110				7,078				(74,828	)				357,360
Commitments and contingencies
Redeemable convertible preferred stock			1,363,580				-				(1,363,580	)	(j)			-
Class A ordinary shares subject to possible redemption			-				85,047				(15,119	)	(a)			-
											(69,928	)	(e)
Stockholders’ equity (deficit)
Preference shares			-				-									-
Ordinary shares
Class A			-				-				1		(e)			-
											(1	)	(g)
Class B			-				-				-		(f)			-
Common stock			3				-				(3	)	(j)			-
New Freenome Common Stock			-				-				2		(d)			11
											1		(i)
											-		(f)
											1		(g)
											7		(j)
Additional paid-in capital			89,471				-				239,998		(d)			1,838,504
											69,927		(e)
											(17,270	)	(h)
											65,522		(i)
											1,363,576		(j)
											(7,606	)	(k)
											34,886		(l)
Accumulated other comprehensive income			28				-									28
Accumulated deficit			(1,479,693	)			(6,297	)			(1,309	)	(h)			(1,514,579	)
											7,606		(k)
											(34,886	)	(l)
Total stockholders’ equity (deficit)			(1,390,191	)			(6,297	)			1,720,452					323,964
Total liabilities, redeemable noncontrolling interest and equity (deficit)		$	398,499			$	85,828			$	196,997				$	681,324

UNAUDITED PRO FORMA CONDENSED COMBINED STATEMENT OF OPERATIONS

FOR THE SIX MONTHS ENDED JUNE 30, 2026

(in thousands, except share and per share data)

		Freenome (Historical)				PCSC (Historical)				Transaction Accounting Adjustments (Note 2)					Pro Forma Combined
Revenue:
License and collaboration revenue		$	5,155			$	-								$	5,155
Service and other revenue			1,341				-									1,341
Total revenue			6,496				-				-					6,496
Operating costs and expenses:
Cost of services			937				-									937
Research and development			106,387				-				1,597		(dd)			107,984
General and administrative			26,624				1,800				(90	)	(aa)			30,612
											1,619		(dd)
											659		(ee)
Total operating costs and expenses			133,948				1,800				3,785					139,533
Loss from operations			(127,452	)			(1,800	)			(3,785	)				(133,037	)
Interest and investment income, net			2,729				-									2,729
Interest expense			(7,863	)			-				6,513		(ff)			(1,350	)
Other income (expense), net			(2	)			-									(2	)
Interest from investments held in Trust Account			-				1,181				(1,181	)	(bb)			-
Unrealized loss on investments held in Trust Account			-				(35	)			35		(bb)			-
Dividend earned on investments held in Trust Account			-				487				(487	)	(bb)			-
Net loss attributable to common stockholders		$	(132,588	)		$	(167	)		$	1,095				$	(131,660	)
Net income (loss) per share, basic		$	(4.97	)		$	(0.02	)							$	(1.19	)
Weighted average shares outstanding, basic			26,696,158				10,984,184									110,280,652
Net income (loss) per share, diluted		$	(4.97	)		$	(0.02	)							$	(1.19	)
Weighted average shares outstanding, diluted			26,696,158				10,984,184									110,280,652

UNAUDITED PRO FORMA CONDENSED COMBINED STATEMENT OF OPERATIONS

FOR THE YEAR ENDED DECEMBER 31, 2025

(in thousands, except share and per share data)

		Freenome (Historical)				PCSC (Historical)				Transaction Accounting Adjustments (Note 2)					Pro Forma Combined
Revenue:
License and collaboration revenue		$	27,139			$	-								$	27,139
Service and other revenue			3,270				-									3,270
Total revenue			30,409				-				-					30,409
Operating costs and expenses:
Cost of services			1,944				-									1,944
Research and development			197,117				-				17,324		(cc)			217,635
											3,194		(dd)
General and administrative			54,817				2,981				(180	)	(aa)			79,736
											17,562		(cc)
											3,238		(dd)
											1,318		(ee)
Total operating costs and expenses			253,878				2,981				42,456					299,315
Loss from operations			(223,469	)			(2,981	)			(42,456	)				(268,906	)
Interest and investment income, net			6,914				-									6,914
Interest expense			(2,820	)			-				1,549		(ff)			(1,271	)
Other income (expense), net			32				-									32
Interest from investments held in Trust Account			-				3,821				(3,821	)	(bb)			-
Unrealized loss on investments held in trust			-				(3	)			3		(bb)			-
Net loss attributable to common stockholders		$	(219,343	)		$	837			$	(44,725	)			$	(263,231	)
Net income (loss) per share, basic		$	(8.28	)		$	0.08								$	(2.39	)
Weighted average shares outstanding, basic			26,497,083				11,067,500									110,280,652
Net income (loss) per share, diluted		$	(8.28	)		$	0.08								$	(2.39	)
Weighted average shares outstanding, diluted			26,497,083				11,067,500									110,280,652

NOTES TO UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL INFORMATION

1. Basis of Presentation

The Business Combination was accounted for as a reverse recapitalization in accordance with U.S. GAAP, whereby PCSC was treated as the acquired company and Freenome was treated as the accounting acquirer. Accordingly, for accounting purposes, the Business Combination was treated as the equivalent of Freenome issuing stock for the net assets of PCSC, accompanied by a recapitalization. The net assets of PCSC were recorded at their historical carrying amounts, which approximates fair value , with no goodwill or other intangible assets recorded. Subsequently, results of operations presented for the periods prior to the Business Combination are those of Freenome.

The unaudited pro forma condensed combined balance sheet as of June 30, 2026 gives pro forma effect to the Business Combination as if it had been consummated on June 30, 2026. The unaudited pro forma condensed combined statements of operations for the six months ended June 30, 2026 and fiscal year ended December 31, 2025 give pro forma effect to the Business Combination as if it had been consummated on January 1, 2025.

The unaudited pro forma condensed combined balance sheet as of June 30, 2026 has been prepared using, and should be read in conjunction with, the following:

• Freenome’s unaudited condensed consolidated balance sheet as of June 30, 2026 and the related notes included as Exhibit 99.1 in this Amendment No. 1; and

• PCSC’s unaudited condensed consolidated balance sheet as of June 30, 2026 and the related notes as filed with the SEC on Form 10-Q on July 15, 2026.

The unaudited pro forma condensed combined statement of operations for the six months ended June 30, 2026 has been prepared using, and should be read in conjunction with, the following:

• Freenome’s unaudited condensed consolidated statement of operations for the six months ended June 30, 2026 and the related notes included as Exhibit 99.1 in this Amendment No. 1; and

• PCSC’s unaudited condensed consolidated statement of operations for the six months ended June 30, 2026 and the related notes as filed with the SEC on Form 10-Q on July 15, 2026.

The unaudited pro forma condensed combined statement of operations for the year ended December 31, 2025 has been prepared using, and should be read in conjunction with, the following:

• Freenome’s audited consolidated statement of operations for the year ended December 31, 2025 and the related notes included in the Proxy Statement/Prospectus; and

• PCSC’s audited consolidated statement of operations for the year ended December 31, 2025 and the related notes as filed with the SEC on Form 10-K on March 12, 2026.

The foregoing historical financial statements have been prepared in accordance with U.S. GAAP. The unaudited pro forma condensed combined financial information has been prepared based on the aforementioned historical financial statements and the assumptions and adjustments as described in the notes to the unaudited pro forma condensed combined financial information. Management has made significant estimates and assumptions in its determination of the pro forma adjustments. As the unaudited pro forma condensed combined financial information has been prepared based on these preliminary estimates, the final amounts recorded may differ materially from the information presented.

The unaudited pro forma condensed combined financial information is not necessarily indicative of what the actual results of operations and financial position would have been had the Business Combination taken place on the dates indicated, nor are they indicative of the future consolidated results of operations or financial position of the post-combination company. They should be read in conjunction with the historical financial statements and notes thereto of Freenome and PCSC.

2. Transaction Accounting Adjustments to Unaudited Pro Forma Condensed Combined Financial Information

The following unaudited pro forma condensed combined financial information has been prepared in accordance with Article 11 of Regulation S-X. The unaudited pro forma condensed combined financial information has been prepared to illustrate the effect of the Business Combination and has been prepared for informational purposes only.

The pro forma combined provision for income taxes does not necessarily reflect the amounts that would have resulted had New Freenome following the Closing, filed consolidated income tax returns during the periods presented.

The pro forma basic and diluted earnings per share amounts presented in the unaudited pro forma condensed combined statements of operations are based upon the number of New Freenome shares outstanding, assuming the Business Combination occurred on January 1, 2025.

Transaction Accounting Adjustments to Unaudited Pro Forma Condensed Combined Balance Sheet

The pro forma adjustments included in the unaudited pro forma condensed combined balance sheet as of June 30, 2026, are as follows:

(a) Represents redemptions of 1,392,723 PCSC Class A Shares at approximately $10.86 per share, or $15.1 million in the aggregate in connection with the Closing.

(b) Reflects the reclassification of cash and investments held in the Trust Account that became available following the Business Combination to cash and cash equivalents.

(c) Reflects the payment of $3.5 million in deferred underwriters’ compensation subject to an agreement with the underwriters.

(d) Reflects proceeds of $240.0 million from the issuance and sale of 24,000,000 shares of New Freenome Common Stock at $10.00 per share in the PIPE Financing pursuant to the Subscription Agreements.

(e) Reflects the reclassification of $69.9 million of PCSC Class A Shares to permanent equity.

(f) Reflects the conversion of 2,156,250 PCSC Class B Shares into 2,156,250 shares of New Freenome Common Stock

(g) Represents the exchange of 6,764,519 PCSC Class A Shares for 6,764,519 shares of New Freenome Common Stock.

(h) Represents preliminary estimated transaction costs incurred by Freenome and PCSC of approximately $13.2 million and $8.9 million, respectively, for legal, financial advisory and other professional fees. PCSC’s estimated transaction costs exclude the deferred underwriting fees as described in Note 2(c) above.

For Freenome’s transaction costs:

• $9.4 million was deferred in other long-term assets and paid by Freenome as of June 30, 2026;

• $1.4 million was deferred in other long-term assets and in accounts payable as of June 30, 2026;

• $0.9 million was deferred in other long-term assets and in accrued expenses as of June 30, 2026;

• $6.2 million was reflected as a reduction of cash, which represents Freenome’s preliminary estimated transaction costs less the amounts previously paid by Freenome;

• $13.2 million were capitalized and offset against the proceeds from the Business Combination and reflected as a decrease in additional paid-in capital.

For PCSC’s transaction costs:

• $3.5 million was accrued by PCSC in accrued expenses and other current liabilities and recognized as expense as of June 30, 2026;

• $8.9 million was reflected as a reduction of cash;

• $4.1 million represents equity issuance costs related to the PIPE financing described in Note 2(d) above and reflected as a decrease in additional paid-in capital; and

• $1.3 million was reflected as an adjustment to accumulated deficit, which represents the total estimated PCSC transaction costs less: (i) $4.1 million capitalized and offset against the proceeds from the PIPE investment; and (ii) $3.5 million previously recognized by PCSC as of June 30, 2026.

(i) Reflects the conversion of the Roche Convertible Note and accrued interest into 6,460,616 shares of New Freenome Common Stock in connection with the Closing.

(j) Reflects the recapitalization of Freenome’s equity consisting of 26,267,598 shares of common stock, 428,560 warrants and 212,541,832 shares of redeemable convertible preferred stock into 68,065,429 shares of New Freenome Common Stock.

(k) Reflects the elimination of PCSC’s historical accumulated deficit after recording the transaction costs to be incurred by PCSC as described in Note 2(h) above.

(l) Represents the recognition of stock-based compensation expense associated with Freenome restricted stock units that, on a pro forma basis, will have vested at the Closing. These costs expensed through Accumulated deficit are included in the unaudited pro forma condensed combined statement of operations for the year ended December 31, 2025 as discussed in Note 2(cc) below.

Transaction Accounting Adjustments to Unaudited Pro Forma Condensed Combined Statements of Operations

The pro forma adjustments included in the unaudited pro forma condensed combined statements of operations for the six months ended June 30, 2026 and year ended December 31, 2025, are as follows:

(aa) Represents pro forma adjustment to eliminate historical expenses related to PCSC’s administrative, financial and support services paid to the Sponsor, which will terminate upon consummation of the Business Combination.

(bb) Represents pro forma adjustment to eliminate interest and unrealized gain (loss) from investments held in Trust Account.

(cc) Represents the recognition of stock-based compensation expense associated with Freenome restricted stock units that, on a pro forma basis, will have vested at the Closing. These costs are reflected as if incurred on January 1, 2025, the date the Business Combination occurred for purposes of the unaudited pro forma condensed combined statements of operations. This is a non-recurring item.

(dd) Reflects the amortization of stock-based compensation expense associated with Freenome’s unvested restricted stock units, which are subject to vesting based upon both a service-based requirement and a liquidity event requirement. At the Closing the liquidity event requirement will have been meet and Freenome will amortize stock-based compensation expense associated with the unvested restricted stock units over the remaining service period.

(ee) Reflects the recognition of stock-based compensation expense associated with the Anti-Dilution Equity Awards that will be granted following the Business Combination, pursuant to the Elliott Offer Letter. The terms of the Elliott Offer Letter provide that an Anti-Dilution Option grant and an Anti-Dilution RSU grant will be made such that the aggregate number of shares underlining outstanding option awards and RSU awards issued to the employee are equal to 0.5% and 0.5%, respectively, of the fully-diluted capitalization of New Freenome following the Closing. The estimated number of Anti-Dilution Options and Anti-Dilution RSUs to be granted are 283,832 options and 283,832 RSUs, respectively. The strike price of the Anti-Dilution Option will be equal to the fair market value of the common stock on the date the new Freenome’s Board approves that grant. The other terms and conditions of the Anti-Dilution Option and Anti-Dilution RSUs, including the vesting commencement date and vesting schedule will be the same as the Initial Option and Initial RSU Award provided for in the employment agreement.

Compensation expense for the Anti-Dilution Option was estimated using the Black-Scholes option pricing model with the estimated $11.15 per share price of New Freenome, 6.3 year expected term, 68.9% estimated volatility and risk-free rate of 4.4%.

Compensation expense for the Anti-Dilution RSU grant is based on the estimated $11.15 per share price of New Freenome.

(ff) Reflects the elimination of interest expense related to the Roche Convertible Note, which will be converted into shares of New Freenome Common Stock as described in Note 2(i) above.

(gg) No income tax adjustment is reflected for the six months ended June 30, 2026 and year ended December 31, 2025 based on Freenome’s estimated annual effective tax rate for the years ending December 31, 2026 and 2025, respectively, and Freenome having a full valuation allowance on its net deferred tax asset.

3. Loss per Share

Represents the net loss per share calculated using the historical weighted average shares outstanding, and the issuance of additional shares in connection with the Business Combination, assuming the shares were outstanding since January 1, 2025. As the Business Combination is being reflected as if it had occurred at the beginning of the periods presented, the calculation of weighted average shares outstanding for basic and diluted net loss per share assumes that the shares issuable relating to the Business Combination and related transactions have been outstanding for the entire periods presented.

		Six Months Ended June 30, 2026				Year Ended December 31, 2025
Pro forma net loss attributable to common shareholders (in thousands)		$	(131,660	)		$	(263,231	)
Pro forma weighted average shares outstanding, basic and diluted			110,280,652				110,280,652
Pro forma net loss per share, basic and diluted		$	(1.19	)		$	(2.39	)
Pro forma weighted average shares calculation, basis and diluted (5)
PCSC public stockholders (2)			6,478,269				6,478,269
Holders of PCSC sponsor shares (3)			2,442,500				2,442,500
PIPE Investors (4)			24,000,000				24,000,000
Freenome equity holders (1)			70,899,267				70,899,267
Roche convertible note			6,460,616				6,460,616
			110,280,652				110,280,652

(1) Includes 2,833,838 shares underlying Freenome restricted stock units that will vest six months following the Closing as the issuance of shares will no longer be contingent on any conditions except the passage of time. Includes 5,371,847 shares of Freenome Common Stock issued to the Perceptive PIPE Investor upon conversion of Freenome capital stock.

(2) Reflects 7,870,992 PCSC Class A Shares outstanding as of June 30, 2026, less 1,392,723 PCSC Class A Shares redeemed in connection with the Closing.

(3) Includes 2,066,250 PCSC Class B Shares and 286,250 PCSC Class A private placement shares held by the Sponsor and 90,000 PCSC Class B Shares held by PCSC independent directors.

(4) Includes 5,500,000 PIPE Shares issued to the Perceptive PIPE Investor, 5,255,376 PIPE Shares issued to an existing Freenome equity holder and 13,244,624 PIPE Shares issued to third-party PIPE Investors.

(5) The pro forma weighted average shares, basic and diluted exclude the following because including them would be antidilutive:

• 3,342,294 shares issuable upon conversion of the Exact Sciences Note;

• 8,272,601 unexercised Freenome stock options;

• 1,201,043 unvested Freenome restricted stock units that remain subject to future service; and

• 14,003 warrants

Filing Exhibits & Attachments

6 documents

Press Releases

• EX-99.1 EXHIBIT 99.1 989.2 KB
• EX-99.2 EXHIBIT 99.2 323.4 KB
• EX-99.3 EXHIBIT 99.3 543.8 KB

Other Documents

• EX-101 XBRL TAXONOMY EXTENSION SCHEMA 3.8 KB
• EX-101 XBRL TAXONOMY EXTENSION LABEL LINKBASE 22.2 KB
• EX-101 XBRL TAXONOMY EXTENSION PRESENTATION LINKBASE 16.2 KB