[Form 4] Guardant Health, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Guardant Health Director Myrtle S. Potter reported multiple securities transactions on June 18, 2025:

• Disposed of 26 shares of Common Stock at $49.47 per share, retaining direct ownership of 18,154 shares
• Acquired new stock options for 6,833 shares with exercise price of $50.57, expiring June 18, 2035
• Received 4,203 Restricted Stock Units (RSUs) at $0 cost basis

Both the stock options and RSUs vest in full on either June 18, 2025, or the date of the next annual stockholders meeting, whichever occurs earlier. The transactions were reported through Form 4 filing, with attorney John G. Saia signing on Potter's behalf on June 20, 2025.

Positive

• Director Myrtle S. Potter received new equity compensation with 6,833 stock options and 4,203 RSUs, aligning long-term interests with shareholders

Negative

• None.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

POTTER MYRTLE S

(Last) (First) (Middle)

3100 HANOVER STREET

(Street)

PALO ALTO CA 94304

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
06/18/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/18/2025		S		26	D	$49.47	18,154	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$50.57	06/18/2025		A		6,833		(1)	06/18/2035	Common Stock	6,833	$0	6,833	D
Restricted Stock Units	$0	06/18/2025		A		4,203		(2)	(3)	Common Stock	4,203	$0	4,203	D

Explanation of Responses:

1. The stock option vests in full on the one-year anniversary of the grant date, June 18, 2025 or the date of the next year annual stockholders meeting, whichever is earlier.

2. The restricted stock units vest in full on the one-year anniversary of the grant date, June 18, 2025 or the date of the next year annual stockholders meeting, whichever is earlier.

3. Not applicable for Restricted Stock Units.

Remarks:

	/s/ John G. Saia, as attorney-in-fact for Myrtle S. Potter	06/20/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider trading activity occurred at Guardant Health (GH) on June 18, 2025?

On June 18, 2025, Director Myrtle S. Potter sold 26 shares of GH common stock at $49.47 per share. Additionally, Potter was granted 6,833 stock options with an exercise price of $50.57 and 4,203 Restricted Stock Units (RSUs).

What is the vesting schedule for GH Director Myrtle Potter's new stock options?

The stock options granted to Myrtle Potter on June 18, 2025 will vest in full on the one-year anniversary of the grant date (June 18, 2025) or the date of the next year annual stockholders meeting, whichever occurs earlier. The options have an expiration date of June 18, 2035.

How many shares of GH stock does Myrtle Potter own after the reported transactions?

Following the reported transactions, Myrtle Potter directly owns 18,154 shares of GH common stock, 6,833 stock options, and 4,203 Restricted Stock Units.

What is the exercise price of GH stock options granted to Myrtle Potter in June 2025?

The stock options were granted with an exercise price of $50.57 per share on June 18, 2025.

When do Myrtle Potter's GH Restricted Stock Units (RSUs) vest?

The 4,203 RSUs granted on June 18, 2025 vest in full on the one-year anniversary of the grant date (June 18, 2025) or the date of the next year annual stockholders meeting, whichever occurs earlier.