Guardant Health CLO exercises RSUs; tax shares withheld

Guardant Health, Inc. Chief Legal Officer John G. Saia reported equity compensation activity on December 15, 2025.

Rhea-AI Filing Summary

Guardant Health, Inc. Chief Legal Officer John G. Saia reported equity compensation activity on December 15, 2025. 1,020 Restricted Stock Units converted into common stock at $0 per share, and 535 common shares were withheld by the company to meet tax withholding obligations at $102.67 per share, as explained in a footnote. After these transactions he directly holds 43,657 shares of Guardant Health common stock.

Insider Trade Summary

1,020 shares exercised/converted

Exercise 3 txns

Insider Saia John G.

Role Chief Legal Officer

Type	Security	Shares	Price	Value
Exercise	Restricted Stock Units	1,020	$0.00	$0.00
Exercise	Common Stock	1,020	$0.00	$0.00
Exercise Price or Tax Liability	Common Stock	535	$102.67	$55K

Holdings After Transaction: Restricted Stock Units — 2,039 contracts (Direct); Common Stock — 43,657 shares (Direct)

Footnotes (3)

1. F1. These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.
2. F2. This represents a restricted stock unit award granted on June 9, 2023 that vests over a three-year period. 33% of the shares subject to such award vested on June 15, 2024 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.
3. F3. Not applicable for Restricted Stock Units.

Key Figures

RSUs converted to common stock: 1,020 shares Shares withheld for tax: 535 shares Tax withholding share price: $102.67 per share +4 more

7 metrics

RSUs converted to common stock 1,020 shares Restricted Stock Units converted into Guardant Health common stock on 2025-12-15

Shares withheld for tax 535 shares Common shares retained by the company to meet tax withholding obligations at $102.67 per share

Tax withholding share price $102.67 per share Per-share value of Guardant Health common stock used for tax withholding on 535 shares

Post-transaction common stock holding 43,657 shares Guardant Health common stock held directly by John G. Saia after the reported transactions

RSU award grant date June 9, 2023 Grant date of the Restricted Stock Unit award described in the footnote

Initial RSU vesting tranche 33% of award First portion of the RSU award vested on June 15, 2024

Remaining RSU vesting 67% of award Remaining RSU shares vest in equal quarterly installments over two years

Key Terms

Restricted Stock Units, tax withholding obligations, vests in equal quarterly installments, exercise or conversion of derivative security

4 terms

Restricted Stock Units financial

"This represents a restricted stock unit award granted on June 9, 2023"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

tax withholding obligations financial

"retained by the Company in order to meet the tax withholding obligations"

vests in equal quarterly installments financial

"the remaining 67% of the shares vests in equal quarterly installments"

exercise or conversion of derivative security financial

"transaction_code_description: Exercise or conversion of derivative security"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What transactions did Guardant Health (GH) insider John G. Saia report?

John G. Saia reported the conversion of 1,020 Restricted Stock Units into Guardant Health common stock at $0 per share, and a tax-related withholding of 535 common shares at $102.67 per share on December 15, 2025, reflecting equity compensation activity.

How many Guardant Health (GH) shares does John G. Saia hold after these transactions?

Following the reported transactions, John G. Saia holds 43,657 shares of Guardant Health common stock directly. This post-transaction holding reflects his position after the RSU conversion and related tax-withholding share retention by the company.

What tax-related transaction was disclosed in Guardant Health (GH) insider filing?

The filing shows 535 Guardant Health common shares were retained by the company at $102.67 per share to satisfy Saia’s tax withholding obligations from RSU vesting, with a footnote stating the amount was not in excess of his tax liability.

What RSU award details were disclosed for Guardant Health (GH) Chief Legal Officer?

A footnote describes a Guardant Health Restricted Stock Unit award granted June 9, 2023, vesting over three years: 33% vested on June 15, 2024, and the remaining 67% vests in equal quarterly installments over the following two years.

What type of securities did John G. Saia convert in the Guardant Health (GH) filing?

John G. Saia converted 1,020 Restricted Stock Units into Guardant Health common stock on December 15, 2025, at a conversion price of $0 per share, reflecting the vesting and settlement of part of his equity compensation.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 12/17/2025 - 07:20 PM EST Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Saia John G.

(Last) (First) (Middle)

3100 HANOVER STREET

(Street)

PALO ALTO CA 94304

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Guardant Health, Inc. [ GH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Legal Officer

3. Date of Earliest Transaction (Month/Day/Year)
12/15/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	12/15/2025		M		1,020	A	$0	44,192	D
Common Stock	12/15/2025		F		535(1)	D	$102.67	43,657	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Restricted Stock Units	$0	12/15/2025		M			1,020	(2)	(3)	Common Stock	1,020	$0	2,039	D

Explanation of Responses:

1. These shares were retained by the Company in order to meet the tax withholding obligations of the award-holder in connection with the vesting of an installment of the restricted stock units. The amount retained by the Company was not in excess of the amount of the tax liability.

2. This represents a restricted stock unit award granted on June 9, 2023 that vests over a three-year period. 33% of the shares subject to such award vested on June 15, 2024 and the remaining 67% of the shares vests in equal quarterly installments over the remaining two-year period thereafter.

3. Not applicable for Restricted Stock Units.

Remarks:

	/s/ John G. Saia	12/17/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.