[Form 4] Genprex, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Genprex, Inc. (GNPX) – Form 4 insider filing reports that President, CEO and CFO Ryan M. Confer had 5,775 common shares withheld on 30 June 2025 to satisfy tax obligations arising from the vesting of previously granted RSUs under the 2018 Equity Incentive Plan. The transaction is coded “F,” indicating it was automatic and non-discretionary for tax payment rather than an open-market sale. The shares were valued at $0.2279 each, reducing Confer’s directly held stake to 32,968 shares. No derivative transactions were reported. Because the event merely settles taxes and involves a modest number of shares, it is typically viewed as neutral regarding the company’s fundamentals and insider sentiment.

Insights

Securities Analyst

TL;DR: Routine tax withholding; negligible impact on insider sentiment or float.

The “F” code confirms an automatic share withholding to cover taxes on RSU vesting—standard practice that does not signal discretionary selling. The 5,775 shares represent a small portion of both the insider’s holdings and Genprex’s total shares outstanding, leaving Confer with 32,968 shares. No option exercises or derivative positions were disclosed. Given the low dollar value (≈$1.3k) and non-discretionary nature, the filing is considered immaterial for valuation or governance analysis.

Corporate Governance Specialist

TL;DR: Compliance event; supports orderly equity incentive administration.

Form 4 shows Genprex continues to administer its 2018 Equity Incentive Plan in line with SEC Section 16 requirements. Automatic withholding avoids open-market sales, reducing potential signaling effects. No red flags regarding trading plans or Rule 10b5-1 are indicated. From a governance perspective, this maintains transparency without altering control dynamics or board independence.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Confer Ryan M.

(Last) (First) (Middle)

3300 BEE CAVE ROAD

#650-227

(Street)

AUSTIN TX 78746

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Genprex, Inc. [ GNPX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President, CEO and CFO

3. Date of Earliest Transaction (Month/Day/Year)
06/30/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/30/2025		F		5,775(1)	D	$0.2279	32,968	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents shares withheld on June 30, 2025 to satisfy tax withholding obligations in connection with the vesting of Restricted Stock Units ("RSUs") previously granted under the Genprex, Inc. (the "Company") 2018 Equity Incentive Plan.

	/s/ Ryan Confer	07/01/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many Genprex (GNPX) shares did CEO Ryan Confer dispose of?

5,775 shares were withheld on 30 June 2025 to pay tax on vested RSUs.

What price was applied to the withheld GNPX shares?

The shares were valued at $0.2279 each for tax withholding purposes.

How many Genprex shares does the CEO own after the transaction?

Ryan Confer now directly owns 32,968 common shares.

Was this an open-market sale by the insider?

No. Transaction code "F" indicates shares were withheld by the company to cover taxes, not sold on the open market.

Does this Form 4 signal bullish or bearish insider sentiment for GNPX?

It is generally viewed as neutral, as the action is administrative rather than a discretionary trade.