[Form 4] GRAIL, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Aaron Freidin, Chief Financial Officer and Director of GRAIL, Inc. (GRAL), reported a sale of 877 shares of GRAIL common stock on 08/19/2025 at a weighted-average price of $32.02 per share. After the reported transactions, he beneficially owns 285,143 shares, held directly. The filing states the sale was executed as a block trade in multiple transactions and that the broker-calculated price is a weighted average; the reporter offers to provide detailed per-trade pricing on request. No derivative transactions were reported.

Positive

• Reporting transparency: filer discloses weighted-average price and offers to provide per-trade details on request
• Continued substantial ownership: reporting person still holds 285,143 shares after the sale

Negative

• Insider sale: 877 shares disposed at a weighted-average price of $32.02, which may be viewed negatively by some investors

Insights

Financial Analyst

TL;DR: A small insider sell reduces holdings modestly; ownership remains significant at 285,143 shares, suggesting no major liquidity event.

The reported sale of 877 shares at $32.02 is immaterial relative to the remaining 285,143 shares owned and likely reflects routine tax or diversification activity rather than a signal of material change in firm outlook. The filer documents a broker-weighted average price and offers granular trade detail on request, which supports transparency. No derivative activity was reported, so there are no option exercises or grants affecting share count.

Corporate Governance Expert

TL;DR: Routine Form 4 disclosure of an officer's small sale; governance controls appear followed with attorney-in-fact signature.

The Form 4 identifies the reporting person as an officer (CFO) and director and includes an attorney-in-fact signature dated 08/20/2025, indicating the reporting process followed formal channels. The filing discloses the mechanics of the sale (block trade, weighted-average price) and affirms willingness to provide per-trade details, which is consistent with good disclosure practice. There are no indications of trading pursuant to a 10b5-1 plan in the form text provided.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Freidin Aaron

(Last) (First) (Middle)

C/O GRAIL, INC.

1525 O'BRIEN DRIVE

(Street)

MENLO PARK CA 94025

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
GRAIL, Inc. [ GRAL ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Financial Officer

3. Date of Earliest Transaction (Month/Day/Year)
08/19/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/19/2025		S		877	D	$32.02(1)	285,143	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The price reported in Column 4 is a weighted average price calculated by the broker executing the sell-to-cover transactions. These shares were sold as part of a block trade in multiple transactions, and the Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate sales price.

Remarks:

	/s/Donald Lang, as Attorney-in-Fact for Aaron Freidin	08/20/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Aaron Freidin (GRAL) report on Form 4?

He reported a sale of 877 shares of GRAIL common stock on 08/19/2025 at a weighted-average price of $32.02, leaving him with 285,143 shares beneficially owned.

Was the sale part of an options exercise or derivative transaction for GRAL?

No. The Form 4 shows this as a non-derivative sale of common stock and no derivative securities were reported.

How was the sale price determined in the GRAL Form 4?

The filing states the price is a broker-calculated weighted average from a block trade executed in multiple transactions and the filer can provide per-trade prices on request.

Who signed the Form 4 for Aaron Freidin?

The form is signed by Donald Lang, attorney-in-fact for Aaron Freidin, dated 08/20/2025.

Does the Form 4 indicate a 10b5-1 trading plan for the GRAL sale?

The provided content does not indicate that the transaction was made pursuant to a 10b5-1 plan.