[SCHEDULE 13G/A] GRAIL, Inc. SEC Filing

Rhea-AI Filing Summary

This Schedule 13G/A reports that PRIMECAP MANAGEMENT CO/CA beneficially owns 2,057,089 shares of GRAIL common stock (class reported as COM), representing 5.72% of the outstanding class. The filing discloses sole voting power over 2,027,466 shares and sole dispositive power over 2,057,089 shares.

The statement affirms the securities are held in the ordinary course of business and were not acquired to change or influence control of the issuer. Items identifying group members, subsidiaries and related classifications are marked not applicable, and the filing includes the certification required under Item 10 attesting to the accuracy of the disclosure.

Positive

• Institutional stake disclosed: PRIMECAP beneficially owns 2,057,089 shares, equal to 5.72% of GRAIL common stock.
• Clear voting/dispositive control: Sole voting power over 2,027,466 shares and sole dispositive power over 2,057,089 shares are explicitly reported.

Negative

• None.

Insights

Securities Analyst

TL;DR PRIMECAP discloses a >5% passive stake in GRAIL with sole voting and dispositive power, a standard institutional disclosure.

The report shows PRIMECAP beneficially owns 2,057,089 shares (5.72%). Sole voting power of 2,027,466 shares implies direct influence over routine proxy matters but does not, by itself, indicate an intent to change control. The filing’s Item 10 certification states the position is held in the ordinary course of business and not to influence control. For investors, this documents institutional ownership and governance presence but contains no operational or financial performance details.

Corporate Governance Expert

TL;DR Reported holdings reflect meaningful institutional ownership without declared intent to alter control; governance impact is limited absent further action.

PRIMECAP’s reported sole voting power over 2,027,466 shares and sole dispositive power over 2,057,089 shares establishes it as an active record-holder for governance purposes. The filing marks group, subsidiary and related disclosures as not applicable, and the certification affirms ordinary-course holdings. Unless PRIMECAP seeks board representation or engages in a coordinated campaign, this filing alone signals stewardship rather than a change in corporate control.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 1)

GRAIL, Inc.

(Name of Issuer)

COM

(Title of Class of Securities)

384747101

(CUSIP Number)

06/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. 384747101

1

Names of Reporting Persons

PRIMECAP MANAGEMENT CO/CA/

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 2,027,466.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 2,057,089.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,057,089.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.72 %

12

Type of Reporting Person (See Instructions)

IA

SCHEDULE 13G

Item 1.
(a)	Name of issuer: GRAIL, Inc.
(b)	Address of issuer's principal executive offices: 1525 O'BRIEN DRIVE, MENLO PARK, CALIFORNIA 94025
Item 2.
(a)	Name of person filing: PRIMECAP MANAGEMENT CO/CA/
(b)	Address or principal business office or, if none, residence: 177 EAST COLORADO BLVD. 11TH FLOOR PASADENA, California 91105
(c)	Citizenship: PRIMECAP MANAGEMENT CO/CA/ - UNITED STATES
(d)	Title of class of securities: COM
(e)	CUSIP No.: 384747101
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 2,057,089
(b)	Percent of class: 5.72 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: PRIMECAP MANAGEMENT CO/CA/ - 2,027,466
	(ii) Shared power to vote or to direct the vote: PRIMECAP MANAGEMENT CO/CA/ - 0
	(iii) Sole power to dispose or to direct the disposition of: PRIMECAP MANAGEMENT CO/CA/ - 2,057,089
	(iv) Shared power to dispose or to direct the disposition of: PRIMECAP MANAGEMENT CO/CA/ - 0
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

PRIMECAP MANAGEMENT CO/CA/

Signature:	Jorge A. Rodriguez
Name/Title:	Deputy Chief Compliance Officer
Date:	08/14/2025

FAQ

Who filed the Schedule 13G/A for GRAIL (GRAL)?

PRIMECAP MANAGEMENT CO/CA filed the Schedule 13G/A reporting its beneficial ownership.

How many GRAIL (GRAL) shares does PRIMECAP beneficially own and what percentage is that?

2,057,089 shares, representing 5.72% of the reported class of GRAIL common stock.

What voting and dispositive powers does PRIMECAP report for GRAL shares?

PRIMECAP reports sole voting power over 2,027,466 shares and sole dispositive power over 2,057,089 shares.

Was the position acquired to influence control of GRAIL (GRAL)?

No. The filing includes a certification that the securities are held in the ordinary course of business and were not acquired to change or influence control of the issuer.

Is the ownership reported on behalf of another person or a group?

No. Items identifying ownership on behalf of another person, group membership and subsidiary acquisition are marked not applicable in the filing.