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Harmony Biosciences names Peter Anastasiou CEO for 2027

Anastasiou's amended employment agreement takes effect with his appointment and continues until terminated in accordance with its terms.

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Form Type
8-K/A

Rhea-AI Filing Summary

Harmony Biosciences Holdings, Inc. announced Jeffrey M. Dayno will retire as the Company's President and Chief Executive Officer and step down as a Class I director effective December 31, 2026, at 11:59 p.m. Eastern Time. Peter Anastasiou, the Company's Senior Executive Vice President and Chief Operating Officer, is appointed President and Chief Executive Officer and a Class I director effective January 1, 2027, at 12:00 a.m. Eastern Time.

Dayno is expected to advise through January 31, 2028 for $500 per hour. Awards held as of the resignation effective date will continue vesting based on his continued service, or vest fully upon a change in control during the consultancy. He is entitled to severance and benefits under his employment and award agreements in exchange for a release of claims and continued compliance with the separation agreement and restrictive covenants.

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance
Key personnel changes including departures, elections, or appointments of directors and executive officers.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, or exhibit attachments filed with this report.
Dayno resignation effective December 31, 2026, at 11:59 p.m. Eastern Time Retirement as President and Chief Executive Officer and departure from the board
Anastasiou appointment effective January 1, 2027, at 12:00 a.m. Eastern Time President and Chief Executive Officer and Class I director
Consulting rate $500 per hour Consulting services by Jeffrey M. Dayno
Consulting period expected through January 31, 2028 Jeffrey M. Dayno's advisory services
continued vesting financial
"continued vesting of any Company equity or equity-based awards"
change in control financial
"full vesting upon a change in control during the consulting period"
A "change in control" occurs when the ownership or management of a company shifts significantly, such as through a merger, acquisition, or sale of a large part of its assets. This change can impact how the company is run and may influence its future direction. For investors, it matters because it can affect the company's stability, strategy, and value, often signaling potential changes in investment risk or opportunity.
restrictive covenants regulatory
"continued compliance with the Separation Agreement and any restrictive covenants"
Restrictive covenants are contract terms that limit what a company, its executives, or shareholders can do—like rules that prohibit selling stock, starting a rival business, or taking on certain debts. Think of them as house rules that protect one party’s interests by keeping risky or competitive actions off the table. For investors they matter because these limits affect a company’s flexibility, governance, potential future value and the ease of exiting an investment.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

When does Peter Anastasiou become HRMY's CEO?

Peter Anastasiou is appointed President and Chief Executive Officer effective January 1, 2027, at 12:00 a.m. Eastern Time, and will also become a Class I director. Jeffrey M. Dayno's departure as President and Chief Executive Officer and Class I director is effective December 31, 2026, at 11:59 p.m. Eastern Time.

How much will HRMY pay Jeffrey Dayno as a consultant?

Dayno is eligible to receive $500 per hour for consulting services and is expected to advise the company through January 31, 2028. Company equity or equity-based awards held as of the resignation effective date will continue vesting based on his continued service, or vest fully upon a change in control during the consulting period.

What conditions apply to Jeffrey Dayno's HRMY severance?

Dayno is entitled to severance payments and benefits in accordance with his employment and award agreements in exchange for a release of claims in favor of the company and its affiliates and continued compliance with the separation agreement and any restrictive covenants.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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0001802665false00018026652026-10-122026-10-12

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

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FORM 8-K/A

(Amendment No.1)

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CURRENT REPORT

Pursuant to Section 13 or 15(d)

of the Securities Exchange Act of 1934

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Date of report (Date of earliest event reported): October 12, 2026

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HARMONY BIOSCIENCES HOLDINGS, INC.

(Exact name of registrant as specified in its charter)

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Delaware

001-39450

82-2279923

(State or other jurisdiction

(Commission

(IRS Employer

of incorporation)

File Number)

Identification No.)

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630 W. Germantown Pike, Suite 215

Plymouth Meeting, PA 19462

(Address of principal executive offices) (Zip Code)

(484) 539-9800

(Registrant’s telephone number, including area code)

N/A

(Former name or former address, if changed since last report.)

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Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

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Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

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Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

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Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

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Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

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Securities registered pursuant to Section 12(b) of the Act:

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Trading

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Name of each exchange

Title of each class

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Symbol(s)

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on which registered

Common Stock, $0.00001 par value per share

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HRMY

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The Nasdaq Global Market

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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).

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Emerging growth company ☐

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If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐

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Explanatory Note

This Current Report on Form 8-K/A amends Item 5.02 of the Current Report on Form 8-K filed by Harmony Biosciences Holdings, Inc. (the “Company”) on October 13, 2026 (the "Original Form 8-K"). On October 12, 2026, the Company announced that Jeffrey M. Dayno, M.D., as part of a leadership succession plan, will be retiring as the Company’s President and Chief Executive Officer and stepping down as a Class I director of the Company’s Board of Directors (the “Board”), in each case, effective as of December 31, 2026, at 11:59 p.m. Eastern Time (the “Resignation Effective Date”), and will serve as a non-executive advisor to the Company through January 2028. On October 12, 2026, the Company also announced that Peter Anastasiou, the Company’s current Senior Executive Vice President, Chief Operating Officer, has been appointed by the Board to serve as President and Chief Executive Officer of the Company and as a Class I director of the Company’s Board, each effective as of January 1, 2027, at 12:00 a.m. Eastern Time (the “Appointment Effective Date”) to fill the vacancy resulting from Dr. Dayno’s resignation.

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The Company is filing this Amendment No. 1 to the Original Form 8-K to provide information regarding each of Dr. Dayno’s and Mr. Anastasiou’s separation and employment arrangements in connection with these transitions, which had not been determined at the time of filing of the Original Form 8-K. Except as set forth herein, no other changes are being made to the Original Form 8-K.

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Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

Separation and Consulting Agreement with Jeffrey M. Dayno

In connection with Dr. Dayno’s departure, on October 29, 2026, the Company, Harmony Biosciences, LLC and Harmony Biosciences Management, Inc. (“Harmony Management”) entered into a Separation and Consulting Agreement with Dr. Dayno (the “Separation Agreement”), pursuant to which Dr. Dayno will be entitled to receive the severance payments and benefits in accordance with his employment agreement and award agreements, in exchange for a release of claims in favor of the Company and its affiliates and continued compliance with the Separation Agreement and any restrictive covenants. In addition, pursuant to the Separation Agreement, Dr. Dayno is expected to provide consulting services to the Company as an advisor through January 31, 2028. During his consultancy, Dr. Dayno will be eligible to receive (x) $500 per hour for any consulting services provided and (y) continued vesting of any Company equity or equity-based awards held by Dr. Dayno as of the Resignation Effective Date based on his continued service with the Company and Harmony Management (or full vesting upon a change in control during the consulting period).

The foregoing description of the Separation Agreement is not complete and is subject to and qualified in its entirety by the terms of the Separation Agreement, a copy of which is filed herewith as Exhibit 10.1 and incorporated herein by reference.

Amended and Restated Employment Agreement with Peter Anastasiou

In connection with Mr. Anastasiou’s appointment as President and Chief Executive Officer, on October 29, 2026, the Company and Harmony Management entered into an Amended and Restated Executive Employment Agreement with Mr. Anastasiou (the “A&R Employment Agreement”), which will become effective as of the Appointment Effective Date and pursuant to which Mr. Anastasiou will serve as President and Chief Executive Officer of the Company and Harmony Management. Mr. Anastasiou’s employment pursuant to the A&R Employment Agreement will continue until terminated in accordance with its terms.

The material changes under the A&R Employment Agreement are as follows:

●Mr. Anastasiou’s annual base salary will be $725,000, effective as of the Appointment Effective Date.
●Commencing with calendar year 2027, Mr. Anastasiou’s target annual bonus opportunity will be equal to 75% of his annual base salary under the Company’s annual bonus program.
●Within 30 days of the Appointment Effective Date, Mr. Anastasiou will be eligible to receive an option award and an award of restricted stock units with an aggregate grant date fair value of $1,750,000 and $750,000, respectively. Each award will vest and, as applicable, become exercisable with respect to 25% of the underlying shares of the award on the first anniversary of the Appointment Effective Date and with respect to 75% of the underlying shares of the award on a quarterly basis thereafter until the fourth anniversary of the Appointment Effective Date, subject to Mr. Anastasiou’s continued service through each vesting date.

The foregoing description of the A&R Employment Agreement is not complete and is subject to and qualified in its entirety by the terms of the A&R Employment Agreement, a copy of which is filed herewith as Exhibit 10.2 and incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

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Exhibit

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Description

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10.1

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Separation and Consulting Agreement by and among Harmony Biosciences Holdings, Inc., Harmony Biosciences, LLC, Harmony Biosciences Management, Inc. and Jeffrey M. Dayno, M.D., dated October 29, 2026.

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Amended and Restated Executive Employment Agreement by and among Harmony Biosciences Holdings, Inc., Harmony Biosciences Management, Inc. and Peter Anastasiou, dated October 29, 2026.

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Cover Page Interactive Data File (embedded within the Inline XBRL document).

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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HARMONY BIOSCIENCES HOLDINGS, INC.

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Date: October 30, 2026

By:

/s/ Christian Ulrich

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Christian Ulrich

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Executive Vice President, General Counsel and Corporate Secretary

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Filing Exhibits & Attachments

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