Harrow, Inc. ownership update: a joint Schedule 13G/A shows Opaleye entities and James Silverman report beneficial ownership of 2,832,230 shares of Harrow common stock. The filing states this equals 7.61% of the class. Opaleye, L.P. separately reports 2,805,000 shares (7.53%), based on 37,229,705 shares outstanding as of February 25, 2026.
The statement clarifies shared voting and dispositive power over the reported shares and is signed by James Silverman on behalf of all reporting persons.
Positive
None.
Negative
None.
Insights
Opaleye reports a mid‑single‑digit stake in Harrow.
The filing lists 2,832,230 shares (7.61%) held with shared voting and dispositive power. It attributes the directly held shares to the Fund and identifies Mr. Silverman as the Adviser's controlling person.
Cash‑flow treatment or planned transactions are not disclosed in the excerpt; subsequent filings would show any trading activity.
Filing is a joint Schedule 13G/A reporting beneficial ownership under passive/beneficial investor rules.
The report is signed jointly and includes the adviser, fund, and an individual; it notes shared voting/dispositive power and repeats the CUSIP 415858109. The filing disclaims an admission of Section 13 beneficial ownership status.
Investors should reference public filings for any changes to holdings or registration status.
Key Figures
Reported shares (Opaleye aggregate):2,832,230 sharesReported shares (Opaleye, L.P.):2,805,000 sharesPercent of class (aggregate):7.61%+2 more
5 metrics
Reported shares (Opaleye aggregate)2,832,230 sharesAmount beneficially owned as stated in Item 4
Reported shares (Opaleye, L.P.)2,805,000 sharesAmount reported for Opaleye, L.P.
Percent of class (aggregate)7.61%Percent of common stock represented by 2,832,230 shares
Percent of class (Opaleye, L.P.)7.53%Percent based on 2,805,000 shares
Shares outstanding used as basis37,229,705 sharesOutstanding shares as of February 25, 2026 (per 10‑K cited)
Key Terms
beneficially owned, shared voting and dispositive power, Schedule 13G/A
3 terms
beneficially ownedregulatory
"Amount beneficially owned: 2,832,230.00"
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
shared voting and dispositive powerregulatory
"Includes shares held in a managed account over which the Adviser has shared voting and dispositive power."
Schedule 13G/Aregulatory
"This statement is filed jointly by (i) Opaleye Management Inc. ..."
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 8)
Harrow, Inc.
(Name of Issuer)
Common Stock, par value $0.001 per share
(Title of Class of Securities)
415858109
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
Opaleye Management Inc.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
MASSACHUSETTS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,832,230.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,832,230.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,832,230.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
7.61 %
12
Type of Reporting Person (See Instructions)
IA, CO
Comment for Type of Reporting Person: Includes shares held in a managed account over which the Adviser has shared voting and dispositive power.
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
Opaleye, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,805,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,805,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,805,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
7.53 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: Based on 37,229,705 shares of Common Stock outstanding as of February 25, 2026, as reported by Harrow, Inc. in its Annual Report on Form 10-K filed with the SEC on March 2, 2026.
SCHEDULE 13G
CUSIP Number(s):
415858109
1
Names of Reporting Persons
James Silverman
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,832,230.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,832,230.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,832,230.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
7.61 %
12
Type of Reporting Person (See Instructions)
IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Harrow, Inc.
(b)
Address of issuer's principal executive offices:
1A Burton Hills Blvd, Suite 200, Nashville, TN 37215
Item 2.
(a)
Name of person filing:
This statement is filed jointly by (i) Opaleye Management Inc. (the "Adviser"), (ii) Opaleye, L.P. (the "Fund"), and (iii) James Silverman (collectively, the "Reporting Persons") with respect to the shares of common stock, par value $0.001 per share (the "Common Stock"), of Harrow, Inc. (the "Issuer") directly held by the Fund. The Adviser serves as investment adviser to the Fund. Mr. Silverman is the controlling person of the Adviser.
The filing of this statement should not be construed as an admission that any of the Reporting Persons is, for purposes of Section 13 of the Securities Exchange Act of 1934, as amended, the beneficial owner of any of the shares reported herein.
(b)
Address or principal business office or, if none, residence:
One Boston Place, 26th Floor, Boston, MA 02108
(c)
Citizenship:
Opaleye Management Inc. - Massachusetts Opaleye, L.P. - Delaware James Silverman - USA
(d)
Title of class of securities:
Common Stock, par value $0.001 per share
(e)
CUSIP No.:
415858109
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
2,832,230.00
(b)
Percent of class:
7.61 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
0
(ii) Shared power to vote or to direct the vote:
2,832,230.00
(iii) Sole power to dispose or to direct the disposition of:
0
(iv) Shared power to dispose or to direct the disposition of:
2,832,230.00
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Opaleye Management Inc.
Signature:
/s/ James Silverman
Name/Title:
President
Date:
05/11/2026
Opaleye, L.P.
Signature:
/s/ James Silverman
Name/Title:
General Partner
Date:
05/11/2026
James Silverman
Signature:
/s/ James Silverman
Name/Title:
Individually
Date:
05/11/2026
Exhibit Information
Exhibit 99.1 Joint Filing Agreement by and among the reporting persons
The filing shows 2,832,230 shares beneficially owned, equal to 7.61% of Harrow's common stock, as stated by the reporting persons in the Schedule 13G/A.
How many shares does Opaleye, L.P. report owning in Harrow?
Opaleye, L.P. reports beneficial ownership of 2,805,000 shares, which the filing lists as 7.53% of the class based on the disclosed outstanding share count.
What outstanding share count does the filing cite for Harrow?
The statement cites 37,229,705 shares outstanding as of February 25, 2026, referenced from Harrow's Annual Report on Form 10‑K filed March 2, 2026.
Who are the reporting persons in this Schedule 13G/A?
The Schedule 13G/A is filed jointly by Opaleye Management Inc., Opaleye, L.P., and James Silverman, with signatures by Mr. Silverman dated May 11, 2026.
Does the filing state whether Opaleye has sole voting power over the shares?
No; the filing shows 0 sole voting power and reports shared voting and dispositive power over the reported 2,832,230 shares.
