iBio, Inc. Schedule 13G/A shows EcoR1 Capital, LLC and related reporting persons beneficially own 1,583,000 shares of Common Stock, representing 4.6% of the class. The filing states the calculation is based on 34,543,561 shares outstanding as of February 9, 2026.
The filing lists shared voting and dispositive power for the reported positions and clarifies EcoR1 is the general partner of the funds while Oleg Nodelman is the control person. Signatures show the filing was executed on May 14, 2026.
Positive
None.
Negative
None.
Insights
EcoR1 reports a sub-5% stake in iBio, disclosed via Schedule 13G/A.
The statement records 1,583,000 shares and a 4.6% ownership percentage using an outstanding share base of 34,543,561 shares as of February 9, 2026. The reported holdings are shown as shared voting and dispositive power, consistent with a fund/manager structure.
Cash‑flow treatment and any planned transactions are not stated; subsequent filings would show changes. Holder decisions and future disclosures will determine whether this position remains passive or becomes active.
Filing emphasizes passive intent and joint filing mechanics.
The filing includes a signed certification that the securities were "not acquired and are not held for the purpose of or with the effect of changing or influencing the control" of the issuer. It also disclaims group membership while describing EcoR1 as general partner and Mr. Nodelman as control person.
Investors may note the ownership below 5% threshold; any future change in intent or aggregation would require amended disclosures under applicable rules.
Key Figures
Reported shares owned (EcoR1):1,583,000 sharesPercent of class (EcoR1):4.6%Shares outstanding used for calculation:34,543,561 shares
3 metrics
Reported shares owned (EcoR1)1,583,000 sharesAmount beneficially owned per Schedule 13G/A
Percent of class (EcoR1)4.6%Percent of Common Stock calculated on 34,543,561 shares outstanding as of <date>February 9, 2026</date>
Shares outstanding used for calculation34,543,561 sharesOutstanding share base cited for percentage calculation as of <date>February 9, 2026</date>
Key Terms
Schedule 13G/A, beneficially owned, shared dispositive power
3 terms
Schedule 13G/Aregulatory
"Schedule 13G/A caption and cover references joint filing agreement"
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
beneficially ownedregulatory
"Item 4 lists 'Amount beneficially owned' for each reporting person"
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
shared dispositive powerregulatory
"Cover sheet columns show 'Shared Dispositive Power 1,583,000.00' for EcoR1"
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
iBio, Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
451033708
(CUSIP Number)
03/31/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
451033708
1
Names of Reporting Persons
EcoR1 Capital, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,583,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,583,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,583,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
4.6 %
12
Type of Reporting Person (See Instructions)
IA, OO
Comment for Type of Reporting Person: Percentage calculated based on 34,543,561 shares of Common Stock outstanding on February 9, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended December 31, 2025.
SCHEDULE 13G
CUSIP Number(s):
451033708
1
Names of Reporting Persons
Oleg Nodelman
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,583,000.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,583,000.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,583,000.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
4.6 %
12
Type of Reporting Person (See Instructions)
HC, IN
Comment for Type of Reporting Person: Percentage calculated based on 34,543,561 shares of Common Stock outstanding on February 9, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended December 31, 2025.
SCHEDULE 13G
CUSIP Number(s):
451033708
1
Names of Reporting Persons
EcoR1 Capital Fund Qualified, L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,488,345.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,488,345.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,488,345.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
4.3 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: Percentage calculated based on 34,543,561 shares of Common Stock outstanding on February 9, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended December 31, 2025.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
iBio, Inc.
(b)
Address of issuer's principal executive offices:
11750 Sorrento Valley Road, Suite 200, San Diego, CA 92121
Item 2.
(a)
Name of person filing:
EcoR1 Capital, LLC, a Delaware limited liability company ("EcoR1")
EcoR1 Capital Fund Qualified, L.P., a Delaware limited partnership ("Qualified Fund")
Oleg Nodelman
Qualified Fund is filing this statement jointly with the other reporting persons, but not as a member of a group, and it expressly disclaims membership in a group. In addition, the filing of this Schedule 13G on behalf of Qualified Fund should not be construed as an admission that it is, and it disclaims that it is, a beneficial owner, as defined in Rule 13d-3 under the Act, of any securities covered by this Schedule 13G. Each reporting person also disclaims beneficial ownership of the securities reported herein except to the extent of that person's pecuniary interest therein.
(b)
Address or principal business office or, if none, residence:
357 Tehama Street #3
San Francisco, CA 94103
(c)
Citizenship:
See Item 4 of the cover sheet for each reporting person.
(d)
Title of class of securities:
Common Stock
(e)
CUSIP No.:
451033708
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(J), so indicate under Item 3(j) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group.
EcoR1 is the general partner and investment adviser of investment funds, including Qualified Fund. Mr. Nodelman is the control person of EcoR1.
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
EcoR1 Capital, LLC
Signature:
/s/ Oleg Nodelman
Name/Title:
Manager
Date:
05/14/2026
Oleg Nodelman
Signature:
/s/ Oleg Nodelman
Name/Title:
Reporting person
Date:
05/14/2026
EcoR1 Capital Fund Qualified, L.P.
Signature:
/s/ Oleg Nodelman
Name/Title:
Manager of the General Partner, EcoR1 Capital, LLC
Date:
05/14/2026
Exhibit Information
EXHIBIT 99 - AGREEMENT REGARDING JOINT FILING OF STATEMENT ON SCHEDULE 13D OR 13G
EcoR1 Capital, LLC and related reporting persons report 1,583,000 shares, representing 4.6% of iBio's Common Stock, using a 34,543,561 share base as of February 9, 2026.
Who besides EcoR1 is named on the Schedule 13G/A for IBIO?
The filing names EcoR1 Capital Fund Qualified, L.P. and Oleg Nodelman as reporting persons, with the Qualified Fund shown holding 1,488,345 shares (4.3%) in the same disclosure.
Does the Schedule 13G/A state EcoR1 seeks control of iBio?
No. The filing includes a signed statement certifying the securities were "not acquired and are not held for the purpose of or with the effect of changing or influencing the control" of the issuer, per the document's language.
What voting and disposition powers are reported by EcoR1 on IBIO shares?
The filing reports 0 shares of sole voting or dispositive power and 1,583,000 shares of shared voting and shared dispositive power for EcoR1 and Oleg Nodelman, per the cover sheet entries.