Welcome to our dedicated page for ImageneBio SEC filings (Ticker: IMA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
ImageneBio, Inc. filings document a Nasdaq-listed biotechnology issuer focused on IMG-007, its anti-OX40 receptor antagonist program for autoimmune and inflammatory diseases. Its 8-K reports disclose operating results, program updates, Regulation FD materials, private-placement and capital-structure matters, and officer or director changes.
Proxy materials cover annual meeting proposals, director elections, auditor ratification, equity incentive plan amendments, and executive compensation governance. The filing record also identifies the company’s common stock on The Nasdaq Capital Market and records formal disclosures tied to its completed reverse-merger corporate history.
ImageneBio, Inc., formerly Ikena Oncology, completed its merger with Legacy Inmagene and now operates as a clinical-stage biopharmaceutical company focused on immune and inflammatory diseases. The business centers on IMG-007, a non-depleting anti-OX40 antibody initially developed for moderate-to-severe atopic dermatitis.
Early Phase 1b/2a data in atopic dermatitis showed meaningful and durable responses, including EASI‑75 rates of 54% and EASI‑90 rates of 31% at Week 16 after a four-week IV dosing period, with sustained biomarker improvements across Th1, Th2 and Th17 pathways. A multi-country Phase 2b subcutaneous dose-finding trial in atopic dermatitis is under way, with topline data expected in 2027.
The company sees IMG-007 as a potential “pipeline within a product,” with exploratory work in alopecia areata and possible future indications such as asthma, rheumatoid arthritis and hidradenitis suppurativa. However, the business remains entirely dependent on IMG-007’s success, expects significant ongoing losses, requires substantial additional funding, faces intense competition from established biologics and JAK inhibitors, and has disclosed a material weakness in internal controls over financial reporting.
ImageneBio, Inc. reported fourth quarter and full-year 2025 results and highlighted progress on its lead antibody IMG-007, now in the Phase 2b ADAPTIVE trial for moderate-to-severe atopic dermatitis.
For 2025, license revenue was $800 thousand compared with $3.5 million in 2024, reflecting lower collaboration income. Research and development expenses were $28.5 million and general and administrative expenses were $20.7 million, bringing total operating expenses to $49.3 million.
Net loss for 2025 was $45.3 million versus $36.6 million in 2024, as the company invested in building out operations after a reverse merger with Ikena Oncology and incurred transaction-related costs. Imagene ended 2025 with $135.3 million in cash, cash equivalents, and marketable securities, up from $12.1 million a year earlier, supported by the merger and a concurrent $75.0 million private placement.
ImageneBio, Inc. filed an initial insider ownership report for Benjamin Porter-Brown, who serves as Chief Medical Officer. This Form 3 does not list any share transactions or holdings, but formally registers his status as an officer subject to insider reporting rules.
ImageneBio, Inc. files a prospectus supplement registering 2,508,337 shares of common stock for resale by selling stockholders. The supplement incorporates parts of a Form 8-K dated February 17, 2026 and updates the Prospectus dated September 15, 2025.
The supplement states the last reported sales price was $6.85 per share on February 13, 2026. The Form 8-K disclosed that Steven Hui Wang resigned from the Board effective February 12, 2026, and the Company says his resignation was not due to any disagreement with the Company on operations, policies, practices or strategy.
ImageneBio, Inc. reported that Steven Hui Wang resigned from its Board of Directors, effective immediately on February 12, 2026. The company stated that his resignation was not due to any disagreement with ImageneBio regarding its operations, policies, practices, or strategy. The filing otherwise reflects routine corporate and listing information, including that ImageneBio’s common stock trades on the Nasdaq Capital Market under the symbol IMA.
Imagenebio, Inc. received an amended Schedule 13G showing that Deep Track Capital, Deep Track Biotechnology Master Fund, Ltd., and David Kroin now report zero beneficial ownership of the company’s common stock. Each reporting person lists 0 shares with 0% of the class and no voting or dispositive power. The filing confirms they own 5 percent or less of Imagenebio’s common stock. The ownership calculations use 11,181,672 shares outstanding as of November 3, 2025, as disclosed in Imagenebio’s prior quarterly report.
ImageneBio, Inc. received a Schedule 13G filing showing that Blue Owl Capital Holdings LP beneficially owns 823,785 shares of ImageneBio common stock. This represents 7.37% of the company’s outstanding common shares, based on 11,181,672 shares reported as outstanding as of November 3, 2025.
Blue Owl reports sole voting and dispositive power over all 823,785 shares and no shared power. The firm certifies that the shares were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of ImageneBio.
ImageneBio, Inc. has filed a prospectus supplement covering the proposed offer and resale from time to time by selling stockholders of 2,508,337 shares of common stock. The supplement incorporates information from a recent current report that notes Chief Medical Officer Yufang Lu, M.D., Ph.D. has notified the company of her resignation, effective December 31, 2025. The company states that her resignation is not due to any disagreement related to operations, policies or practices. ImageneBio is conducting a search for her replacement, and Dr. Lu is expected to provide transition advisory services after her resignation date. The company’s common stock trades on the Nasdaq Capital Market under the symbol IMA, and last traded at $6.24 per share on December 17, 2025.
Imagenebio, Inc. reported that its Chief Medical Officer, Yufang Lu, M.D., Ph.D., has given notice of her resignation effective December 31, 2025. The company states that Dr. Lu’s decision is not due to any disagreement regarding its operations, policies, or practices, which suggests the change is not driven by internal conflict.
Imagenebio is beginning a search for a new Chief Medical Officer, an important role overseeing its medical and clinical programs. Dr. Lu is expected to provide transition advisory services after her resignation date, helping to maintain continuity in the company’s clinical and medical activities while leadership responsibilities are handed over to her eventual successor.
IMAGENEBIO, INC. (IMA) filed a current report to announce that it has updated its corporate presentation for use in meetings with investors, analysts and other interested parties. The updated presentation, dated November 19, 2025, is being made available on the company’s website and is also included as Exhibit 99.1 to this report.
The company notes that the information in this investor presentation and in this report under Item 7.01 is being furnished rather than filed under securities laws, which means it is not automatically incorporated into other securities filings unless specifically referenced there.