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Inhibitor Therapeutics, Inc. is a pre‑revenue pharmaceutical development company focused on repurposing the antifungal itraconazole to treat basal cell carcinoma nevus syndrome (Gorlin Syndrome). Its lead evidence comes from the HP2001 Phase IIb study in 38 patients with 477 baseline lesions, where per‑lesion objective response was reported at 57.7% and patient‑level disease control at 97.4%.
The company has an FDA Type C meeting granted for its BCCNS program, with written responses expected in May 2026, and holds orphan‑drug designation for itraconazole in this indication. It has engaged Avior Bio to create a proprietary micronized/amorphous itraconazole formulation and licenses angiogenesis‑related IP from Johns Hopkins, aiming to build layered exclusivity.
INTI has minimal operations, only eight employees, no commercial products and no current revenue. It depends on new capital and potential strategic transactions, including a February 2026 securities purchase agreement for $3 million plus warrant funding that is not assured to close. The filing highlights substantial risks: early‑stage clinical status, regulatory uncertainty around its proposed per‑lesion endpoint strategy and 505(b)(2) path, reliance on a small leadership team, intense competition, and a thin, volatile OTCQB trading market. Management acknowledges significant doubt about the ability to continue as a going concern without additional financing or deals.
Inhibitor Therapeutics, Inc. entered into a Securities Purchase Agreement with an institutional investor to raise $3,000,000. The company agreed to sell 12,000,000 shares of common stock and issue a warrant to purchase up to 7,000,000 additional shares at $0.25 per share and accompanying warrant.
The warrant will be exercisable for three years at an exercise price of $0.35 per share, which could provide up to an additional $2,450,000 in gross proceeds if fully exercised. As of the filing date, the financing had not yet closed, and the investor agreed under a lock-up to refrain from selling the financing and warrant shares for nine months after the SPA date or until a change in control.
Inhibitor Therapeutics (INTI) reported Q3 2025 results marked by ongoing development work and no product revenue. The company posted a net loss of $712,184 for the quarter and $2,004,972 for the nine months. Operating expenses were steady, with R&D $377,789 and G&A $363,426 in Q3. Interest income was $29,031 in Q3.
Cash and cash equivalents were $2,976,658 as of September 30, 2025 (from $5,606,863 at year-end), reflecting net cash used in operations of $2,630,205 year-to-date. The balance sheet shows $3,000,000 in deferred royalty advances tied to the BCCNS program. The company advanced regulatory preparations around itraconazole for BCCNS, engaged Avior for a finalized formulation and a PK crossover study, and applied to FDA’s RDEA pilot. Subsequent events include a 2025 Equity Incentive Plan for up to 20,000,000 shares subject to shareholder approval and a performance-based consulting agreement with Frameshift featuring warrant eligibility upon defined milestones. 172,573,545 shares were outstanding as of November 13, 2025.
Inhibitor Therapeutics (INTI) reported two corporate actions. The company entered a performance-based master services agreement with Frameshift Management, Inc. to provide biostatistics, regulatory, business development and strategic consulting supporting its basal cell carcinoma programs in Gorlin’s syndrome. Services commenced on October 21, 2025, with compensation at a previously agreed rate and unvested equity compensation realized only after requirements described in the agreement.
The Board also approved the 2025 Equity Incentive Plan, reserving up to 20,000,000 shares of common stock for awards, including options, RSUs, and other stock- or cash-based awards. Shareholder approval is planned within 12 months of adoption; if not received in time, the plan and any awards made under it will terminate.