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Inozyme Pharma, Inc. SEC Filings

INZY NASDAQ

Welcome to our dedicated page for Inozyme Pharma SEC filings (Ticker: INZY), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Parsing a biotech filing loaded with pharmacokinetic charts, trial protocols, and revenue-less cash-flow tables can feel overwhelming. Inozyme Pharma’s SEC disclosures are especially dense because every 10-Q must outline patient-enrollment updates, orphan-drug milestones, and runway projections. Investors who just want to know whether INZ-701 hit a safety endpoint—or if directors are accumulating stock—shouldn’t wade through 200 pages.

Stock Titan turns those complexities into clarity. Our AI-powered summaries flag exactly where “understanding Inozyme Pharma SEC documents with AI” matters: the section explaining ENPP1 and ABCC6 data in the Inozyme Pharma quarterly earnings report 10-Q filing, risk-factor shifts in the Inozyme Pharma annual report 10-K simplified, and any surprise Inozyme Pharma 8-K material events explained. Real-time alerts on Inozyme Pharma insider trading Form 4 transactions and Inozyme Pharma executive stock transactions Form 4 arrive seconds after EDGAR posts, letting you gauge leadership sentiment before the market reacts.

Every filing type is covered—from the Inozyme Pharma proxy statement executive compensation that details option grants to the S-3 shelf registration outlining future capital needs. Use our platform to:

  • Compare R&D spend across periods with the Inozyme Pharma earnings report filing analysis.
  • Track each Inozyme Pharma Form 4 insider transactions real-time notice for buying or selling patterns.
  • Download study-level data tables straight from exhibits without searching.

Whether you ask, “What does Inozyme Pharma report in their SEC filings?” or “Where can I find an Inozyme Pharma quarterly earnings report 10-Q filing?”, you’ll land here. Explore “Inozyme Pharma SEC filings explained simply” and move from raw data to actionable insight in minutes—AI explained, investor approved.

Rhea-AI Summary

Inozyme Pharma COO Matthew Winton acquired 14,355 shares of common stock on June 25, 2025, through the company's Employee Stock Purchase Plan (ESPP). The shares were purchased at $0.74 per share, representing 85% of the closing price on April 1, 2025, the first day of the purchase period.

Following this transaction, Winton's direct beneficial ownership increased to 21,743 shares. The purchase was made during the ESPP period running from April 1, 2025, through June 25, 2025.

  • Transaction Type: Stock Purchase through ESPP
  • Purchase Price: $0.74 per share (15% discount)
  • Ownership Form: Direct
  • Filing Status: Individual filing

This insider purchase through the ESPP demonstrates continued participation in company equity programs by key executive leadership.

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Rhea-AI Summary

Insider Trading Alert: Douglas A. Treco, CEO & Chairman of Inozyme Pharma (NASDAQ: INZY), acquired 2,815 shares of common stock on June 25, 2025, through the company's Employee Stock Purchase Plan (ESPP).

Key Transaction Details:

  • Purchase price: $0.74 per share (85% of closing price on April 1, 2025)
  • Total shares owned after transaction: 43,861 shares
  • Ownership type: Direct
  • ESPP purchase period: April 1, 2025 - June 25, 2025

The transaction was executed under the company's 2020 ESPP, which allows employees to purchase company stock at a discount. This insider purchase by the CEO demonstrates continued alignment with shareholder interests and potential confidence in the company's prospects.

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Inozyme Pharma (INZY) SVP, CFO & Head of BD Sanjay Subramanian reported the acquisition of 6,813 shares of common stock on June 25, 2025, through the company's Employee Stock Purchase Plan (ESPP).

Key transaction details:

  • Purchase price: $0.74 per share (85% of closing price on April 1, 2025)
  • ESPP purchase period: April 1, 2025 - June 25, 2025
  • Total shares owned after transaction: 39,701 shares
  • Ownership form: Direct

This insider purchase through the ESPP demonstrates continued participation in company equity programs by a key executive officer. The transaction was executed under the company's 2020 Employee Stock Purchase Plan, which allows employees to purchase shares at a discount to market price.

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Inozyme Pharma has announced the postponement of its 2025 Annual Meeting of Stockholders, originally scheduled for June 25, 2025, due to a pending acquisition by BioMarin Pharmaceutical. If the acquisition completes, no public stockholder annual meeting will be held. If it doesn't proceed, the Board will reschedule the meeting with a new record date.

Key Company Profile:

  • Clinical-stage biopharmaceutical company with ~50 Boston-based employees
  • Focuses on PPi-Adenosine Pathway therapeutics for bone health and blood vessel function
  • Lead therapy INZ-701, an ENPP1 Fc fusion protein, is in late-stage clinical trials
  • Target conditions include ENPP1 Deficiency, ABCC6 Deficiency, and calciphylaxis

The filing includes detailed information about the tender offer process and directs stockholders to review important acquisition-related documents filed with the SEC by both companies. Materials are available on the SEC website and both companies' respective websites.

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FAQ

What is the current stock price of Inozyme Pharma (INZY)?

The current stock price of Inozyme Pharma (INZY) is $3.99 as of June 28, 2025.

What is the market cap of Inozyme Pharma (INZY)?

The market cap of Inozyme Pharma (INZY) is approximately 257.6M.

What is the core focus of Inozyme Pharma, Inc.?

Inozyme Pharma is focused on developing novel enzyme replacement therapies for rare diseases, particularly those affecting bone health, vascular function, and soft tissues through targeting the PPi-Adenosine pathway.

Which conditions are primarily targeted by the company?

The company primarily targets conditions such as ENPP1 Deficiency, ABCC6 Deficiency, and calciphylaxis, which are characterized by pathologic mineralization and abnormal vascular smooth muscle proliferation.

What is INZ-701?

INZ-701 is a recombinant, genetically engineered fusion protein that functions as an enzyme replacement therapy aimed at restoring the balance in the PPi-Adenosine pathway to counteract disorders of mineralization and intimal proliferation.

How does INZ-701 work in the body?

INZ-701 metabolizes extracellular ATP to generate inorganic pyrophosphate (PPi), which inhibits abnormal mineralization, and produces adenosine, which helps regulate vascular smooth muscle proliferation.

What stage of development is Inozyme Pharma currently in?

Inozyme Pharma is a clinical-stage biopharmaceutical company actively conducting early-phase trials and natural history studies to evaluate the safety and efficacy of its therapeutic candidates.

Why is the PPi-Adenosine pathway significant?

The PPi-Adenosine pathway plays a crucial role in regulating mineralization and vascular smooth muscle proliferation. Disruptions in this pathway can lead to severe conditions such as ENPP1 and ABCC6 Deficiencies, making it a key target for therapeutic intervention.

How does Inozyme Pharma differentiate itself from its competitors?

The company differentiates itself through its specialized focus on the PPi-Adenosine pathway and the development of targeted enzyme replacement therapies, supported by deep scientific expertise and comprehensive clinical research.

What is the potential impact of Inozyme Pharma's research?

By addressing the underlying molecular mechanisms of rare metabolic disorders, Inozyme Pharma's research has the potential to significantly improve clinical outcomes and quality of life for patients suffering from debilitating conditions with limited treatment options.

Are there any approved therapies for the targeted diseases?

Currently, there are no approved therapies that effectively address the underlying causes of ENPP1 Deficiency, ABCC6 Deficiency, or calciphylaxis, which underscores the importance of Inozyme Pharma's innovative approach.
Inozyme Pharma, Inc.

NASDAQ:INZY

INZY Rankings

INZY Stock Data

257.60M
63.17M
1.2%
92.62%
6.83%
Biotechnology
Pharmaceutical Preparations
Link
United States
BOSTON