Patrick O'Neil reports planned IONS share sales in Form 144

IONS filing reports proposed sales of Common Stock by Patrick O'Neil.

Rhea-AI Filing Summary

IONS filing reports proposed sales of Common Stock by Patrick O'Neil. The document lists two transactions: 9,191 shares on 01/06/2026 for $700,602.00 and 6,179 shares on 01/30/2026 for $512,905.00. The filing also references Restricted Stock Units dated 01/15/2018 and an indicated share count of 165,190,000 as of 03/09/2026.

Insights

Securities Compliance Analyst

Form 144 records proposed insider sales by Patrick O'Neil; amounts and dates are disclosed.

The filing lists two proposed disposals with exact share counts and consideration: $700,602.00 for 9,191 shares on 01/06/2026 and $512,905.00 for 6,179 shares on 01/30/2026. These entries serve as a regulatory notice of intended sales rather than proof of completed trades.

Restricted Stock Units dated 01/15/2018 are noted in the securities section. Cash‑flow treatment and whether sales closed are not specified in the excerpt; subsequent filings or transaction confirmations would show completion.

FAQ

What does the IONS Form 144 filed by Patrick O'Neil disclose?

It discloses proposed sales of Common Stock by Patrick O'Neil on two dates. The filing lists 9,191 shares on 01/06/2026 for $700,602.00 and 6,179 shares on 01/30/2026 for $512,905.00, and notes RSUs dated 01/15/2018.

Does the Form 144 mean the IONS shares were sold?

No, Form 144 signals intent to sell but does not confirm completion. It reports proposed disposals with dates and amounts; trade settlement or confirmations would appear in later filings if completed.

How many IONS shares and dollar amounts are listed for sale by O'Neil?

The filing lists two amounts: 9,191 shares at $700,602.00 and 6,179 shares at $512,905.00. Each line pairs a share count with the stated aggregate consideration.

What securities other than common stock are referenced in the IONS filing?

The filing references Restricted Stock Units dated 01/15/2018 in the securities section. No exercise prices or additional RSU amounts are provided in the excerpt.

Is there an outstanding share count shown in the Form 144 excerpt for IONS?

The excerpt shows an indicated share count of 165,190,000 with a date of 03/09/2026. This appears as a reported figure in the header of the filing content.

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Accepted by SEC EDGAR 03/09/2026 - 04:16 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001564926
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	O'NEIL PATRICK R.
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	13217	994612.00	165190000	03/09/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/15/2018	Restricted Stock Units	Issuer			13217	01/15/2018	Equity Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Patrick O'Neil 2855 Gazette Ct Carlsbad CA 92010	Common Stock	01/30/2026	6179	512905.00
Patrick O'Neil 2855 Gazette Ct Carlsbad CA 92010	Common Stock	01/06/2026	9191	700602.00

144: Remarks and Signature

Remarks
Date of Notice	03/09/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	12/08/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Luca Lotito, as a duly authorized representative of STIFEL, as attorney-in-fact for Patrick O'Neil
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)