Insider files to sell 8,000 shares via option exercise

Reported proposed sale of 8,000 shares by an insider via stock option exercise.

Rhea-AI Filing Summary

Reported proposed sale of 8,000 shares by an insider via stock option exercise. The filing shows a stock option exercise to sell 8,000 shares with a transaction date of 06/15/2026. A prior sale listed 8,000 shares on 06/01/2026 for $605,360.00.

Insights

Securities Counsel

Routine insider sale notice under Form 144 tied to option exercise; no broader corporate action shown.

The filing lists a stock option exercise and proposed sale of 8,000 shares on 06/15/2026. Form 144 is a regulatory notice of intended resale and does not itself complete the sale.

Timing and cash‑flow treatment are disclosed as cash and an earlier sale on 06/01/2026 recorded $605,360.00. Subsequent filings would show settlement details.

Key Figures

Shares proposed for resale: 8,000 shares Prior sale recorded: 8,000 shares Proceeds shown for prior sale: $605,360.00

3 metrics

Shares proposed for resale 8,000 shares stock option exercise scheduled for 06/15/2026

Prior sale recorded 8,000 shares sale dated 06/01/2026

Proceeds shown for prior sale $605,360.00 amount tied to 8,000-share sale on 06/01/2026

Key Terms

Form 144, stock option exercise, issuer

3 terms

Form 144 regulatory

"Filing header and transaction rows referencing proposed resale notice"

Form 144 is a document that investors must file with the government when they plan to sell a large number of shares of a company's stock. It helps ensure transparency so everyone knows how many shares are being sold and when, which can impact the stock's price.

stock option exercise financial

"Securities To Be Sold line indicating 'Stock Option Exercise' as the transaction type"

A stock option exercise is the act of using a previously granted right to buy shares of a company's stock at a specific, predetermined price by paying that price and receiving the shares. It matters to investors because exercising changes who owns the shares (which can dilute existing ownership), can trigger taxable events and shift potential gains or losses, and affects voting power and the company’s outstanding share count—like turning a voucher into an actual product that becomes part of circulating supply.

issuer regulatory

"Securities To Be Sold line lists 'Issuer' as the seller relationship"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the IONS Form 144 report?

It reports a proposed resale of 8,000 shares tied to a stock option exercise with a transaction date of 06/15/2026. The filing is a notice of intent to sell under federal resale rules.

Who is the seller in the IONS filing?

Spencer R. Berthelsen is identified with an address in Carlsbad, CA, and prior activity showing 8,000 shares sold on 06/01/2026 for $605,360.00.

How many shares are involved in the proposed resale?

The filing lists a proposed resale of 8,000 shares associated with a stock option exercise scheduled for 06/15/2026. The notice specifies the sale method as cash.

Does Form 144 mean the sale is complete?

No. Form 144 is a regulatory notice of an intended resale under Rule 144; it does not confirm completion. Settlement and final disposition would appear in later disclosures if they occur.

What monetary amount is shown in the filing?

An earlier entry shows a sale amount of $605,360.00 for 8,000 shares dated 06/01/2026. The proposed resale entry does not list a sale price in the excerpt.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 06/15/2026 - 10:17 AM EDT Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001181548
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	IONIS PHARMACEUTICALS INC
SEC File Number	000-19125
Address of Issuer	2855 GAZELLE COURT CARLSBAD CALIFORNIA 92010
Phone	7609319200
Name of Person for Whose Account the Securities are To Be Sold	BERTHELSEN SPENCER R
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Director

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Fidelity Brokerage Services LLC 900 Salem Street Smithfield RI 02917	8000	587920.00	165262556	06/15/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	06/15/2026	Stock Option Exercise	Issuer			8000	06/15/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Spencer R. Berthelsen 2855 Gazelle Court Carlsbad CA 92010	Common	06/01/2026	8000	605360.00

144: Remarks and Signature

Remarks
Date of Notice	06/15/2026
Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1	09/09/2025
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/Wade Moss, as a duly authorized representative of Fidelity Brokerage Services LLC, as attorney-in-fact for Spencer R. Berthelsen
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)