[144] IONIS PHARMACEUTICALS INC SEC Filing

Rhea-AI Filing Summary

IONS filed a Form 144 reporting proposed sales of Common Stock by an affiliate. The filing lists securities tied to option exercises dated 01/02/2024, 01/03/2023, and 01/03/2022 with quantities 10,461, 4,145, and 5,500, and Restricted Stock Units dated 01/13/2024 totaling 15,937 shares.

The filing also discloses recent sales by Shannon Devers: 44,199 shares on 01/07/2026 ($3,756,915.00), 8,353 shares on 01/16/2026 ($636,626.00), and 3,977 shares on 01/22/2026 ($323,490.00).

Insights

Securities Compliance Counsel

Form 144 notifies a planned resale of affiliate-held common stock and records recent insider sales.

The filing itemizes securities associated with option exercises and RSUs with explicit quantities and dates. It also documents executed sales by a named holder with share counts and gross proceeds listed in the excerpt.

These disclosures are procedural notices under resale rules; timing and methods of any future sales are not specified in the provided excerpt.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	39014	3101613.00	161970000	03/03/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/02/2024	Option Exercise	Issuer			10461	03/03/2026	Cash
Common Stock	01/03/2023	Option Exercise	Issuer			4145	03/03/2026	Cash
Common Stock	01/03/2022	Option Exercise	Issuer			5500	03/03/2026	Cash
Common Stock	01/13/2024	Restricted Stock Units	Issuer			15937	01/13/2024	Equity Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	01/07/2026	44199	3756915.00
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	01/22/2026	3977	323490.00
Shannon Devers 1367 Gazelle Ct Carlsbad CA 92010	Common Stock	01/16/2026	8353	636626.00

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)