Brett Monia to sell 290,203 Ionis (IONS) shares under Rule 144

Rhea-AI Filing Summary

IONS filer Brett Monia submitted a Rule 144 notice for the proposed sale of 290,203 shares of common stock through Stifel Nicolaus & Company Inc. on or about 02/06/2026 on Nasdaq, with an aggregate market value of 24826867.00.

The shares to be sold were acquired on 01/15/2026 as restricted stock units from the issuer as equity compensation. The notice states that 161,974,393 shares of this class were outstanding. During the prior three months, Monia sold 44,034 and 62,970 shares of common stock for gross proceeds of 3357167.00 and 5223749.00, respectively.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common Stock	Stifel Nicolaus & Company Inc 501 N Broadway St. Louis MO 63102	290203	24826867.00	161974393	02/06/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common Stock	01/15/2026	Restricted Stock Units	Issuer			290203	01/15/2026	Equity Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
Brett Monia 2855 Gazelle Ct Carlsbad CA 92010	Common Stock	01/16/2026	44034	3357167.00
Brett Monia 2855 Gazelle Ct Carlsbad CA 92010	Common Stock	01/30/2026	62970	5223749.00

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

How many IONS shares does Brett Monia plan to sell under this Rule 144 notice?

Brett Monia plans to sell 290,203 shares of IONS common stock under this Rule 144 notice. The proposed sale will be executed through Stifel Nicolaus & Company Inc. on Nasdaq, with an aggregate market value reported as 24826867.00.

When were the IONS shares to be sold by Brett Monia acquired and how?

The shares to be sold were acquired on 01/15/2026 as restricted stock units from the issuer. The consideration is described as equity compensation, meaning the securities were granted rather than bought for cash on that date.

What is the reported aggregate market value of Brett Monia’s planned IONS stock sale?

The Rule 144 notice reports an aggregate market value of 24826867.00 for the 290,203 common shares to be sold. This figure reflects the total market value of the proposed sale at the time of the filing’s calculation.

How many IONS shares of this class are reported as outstanding in the notice?

The filing states that 161,974,393 shares of the relevant class of IONS common stock were outstanding. This number provides context for the size of the planned sale relative to the issuer’s total shares of that class.

What prior IONS stock sales by Brett Monia are disclosed in the last three months?

The notice lists two recent sales: 44,034 shares of common stock sold on 01/16/2026 for gross proceeds of 3357167.00, and 62,970 shares sold on 01/30/2026 for gross proceeds of 5223749.00.

Which broker and exchange are involved in Brett Monia’s planned IONS share sale?

The planned sale will be handled by Stifel Nicolaus & Company Inc., located in St. Louis, Missouri. The Nasdaq stock market is named as the securities exchange where the common stock will be sold under this Rule 144 notice.