Indicate by check mark whether the registrant files or will file
annual reports under cover of Form 20-F or Form 40-F:
Pursuant to the requirements of the Securities Exchange Act of 1934,
as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Exhibit 99.1

IsoEnergy Completes C$25
Million Concurrent Private Placement with NexGen Energy
All monetary amounts are expressed
in Canadian Dollars, unless otherwise indicated.
TORONTO, Jan. 27, 2026 /CNW/ - IsoEnergy Ltd.
(NYSE American: ISOU) (TSX: ISO) (the "Company" or "IsoEnergy") is pleased to announce that, further
to its press release dated January 20, 2026 and in connection with the completion of its bought deal financing (the "Offering"),
the Company has also closed its non-brokered private placement (the "Concurrent Private Placement") pursuant to which
the Company issued 1,666,667 common shares of the Company (the "Shares") at a price of C$15.00 per Share to NexGen
Energy Ltd. ("NexGen") for aggregate gross proceeds of C$25,000,005.
The proceeds from the Concurrent Private Placement
are expected to be used to fund the continued development and further exploration of the Company's mineral properties, and for general
corporate purposes.
The Concurrent Private Placement was completed to
enable NexGen to maintain its pro rata ownership interest in the Company at approximately 30% after giving effect to the Offering. The
Shares issued pursuant to the Concurrent Private Placement are subject to a statutory hold period of four months and one day following
the closing of the Concurrent Private Placement. No commission or other fee is payable in connection with the sale of Shares pursuant
to the Concurrent Private Placement.
This press release shall not constitute an offer
to sell or the solicitation of an offer to buy nor shall there be any sale of the securities in any state in which such offer, solicitation
or sale would be unlawful. The securities have not been, nor will they be, registered under the United States Securities Act of 1933,
as amended (the "U.S. Securities Act") and may not be offered or sold in the United States absent registration or an applicable
exemption from the registration requirements of the U.S. Securities Act, and applicable state securities laws.
NexGen's participation in the Concurrent Private Placement
constitutes a "related party transaction" pursuant to Multilateral Instrument 61-101 – Protection of Minority
Security Holders in Special Transactions ("MI 61-101"). The Company is exempt from the requirement to obtain
a formal valuation or minority shareholder approval in connection with the Concurrent Private Placement under MI 61-101 in reliance on
Sections 5.5(a) and 5.7(1)(a) of MI 61-101 due to the fair market value of the Concurrent Private Placement being below 25% of the Company's
market capitalization for purposes of MI 61-101. The Company was not able to file a material change report 21 days prior to the closing
date of the Concurrent Private Placement as a result of the closing date. The Concurrent Private Placement was approved by the board of
directors of the Company with each of Messrs. Curyer, Patricio and McFadden having disclosed his interest in the Concurrent Private Placement
and abstaining from voting in respect thereof. The Company has not received, nor has it requested a valuation of its securities or the
subject matter of the Concurrent Private Placement in the 24 months prior to the date hereof.
About IsoEnergy Ltd.
IsoEnergy (NYSE American: ISOU; TSX: ISO) is a leading,
globally diversified uranium company with substantial current and historical mineral resources in top uranium mining jurisdictions of
Canada, the U.S. and Australia at varying stages of development, providing near-, medium- and long-term leverage to rising uranium prices.
IsoEnergy is currently advancing its Larocque East project in Canada's Athabasca basin, which is home to the Hurricane deposit, boasting
the world's highest-grade indicated uranium mineral resource. IsoEnergy also holds a portfolio of permitted past-producing, conventional
uranium and vanadium mines in Utah with a toll milling arrangement in place with Energy Fuels. These mines are currently on standby, ready
for rapid restart as market conditions permit, positioning IsoEnergy as a near-term uranium producer.
Neither the Toronto Stock Exchange nor its Regulation
Services Provider (as that term is defined in the policies of the Exchange) accepts responsibility for the adequacy or accuracy of this
press release.
Disclosure regarding forward-looking statements
This press release contains "forward-looking
statements" within the meaning of the United States Private Securities Litigation Reform Act of 1995 and "forward-looking information"
within the meaning of applicable Canadian securities legislation (collectively, referred to as "forward-looking information").
Generally, forward-looking information can be identified by the use of forward-looking terminology such as "plans", "expects"
or "does not expect", "is expected", "budget", "scheduled", "estimates", "forecasts",
"intends", "anticipates" or "does not anticipate", or "believes", or variations of such words
and phrases or state that certain actions, events or results "may", "could", "would", "might"
or "will be taken", "occur" or "be achieved". This forward-looking information may relate to the Concurrent
Private Placement, including statements with respect to the anticipated use of the net proceeds from the Concurrent Private Placement;
and any other activities, events or developments that the Company expects or anticipates will or may occur in the future.
Forward-looking statements are necessarily based
upon a number of assumptions that, while considered reasonable by management at the time, are inherently subject to business, market and
economic risks, uncertainties and contingencies that may cause actual results, performance or achievements to be materially different
from those expressed or implied by forward-looking statements. Such assumptions include, but are not limited to, the price of uranium;
and that general business and economic conditions will not change in a materially adverse manner. Although IsoEnergy has attempted to
identify important factors that could cause actual results to differ materially from those contained in forward-looking information, there
may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such information
will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements.
Accordingly, readers should not place undue reliance on forward-looking information.
Such statements represent the current views of
IsoEnergy with respect to future events and are necessarily based upon a number of assumptions and estimates that, while considered reasonable
by IsoEnergy, are inherently subject to significant business, economic, competitive, political and social risks, contingencies and uncertainties.
Risks and uncertainties include, but are not limited to the following: regulatory determinations and delays; stock market conditions generally;
demand, supply and pricing for uranium; and general economic and political conditions in Canada, the United States and other jurisdictions
where the applicable party conducts business. Other factors which could materially affect such forward-looking information are described
in the risk factors in IsoEnergy's most recent annual management's discussion and analysis or annual information form and IsoEnergy's
other filings with the Canadian securities regulators which are available under the Company's profile on SEDAR+ at www.sedarplus.ca. IsoEnergy
does not undertake to update any forward-looking information, except in accordance with applicable securities laws.
View original content to download multimedia:https://www.prnewswire.com/news-releases/isoenergy-completes-c25-million-concurrent-private-placement-with-nexgen-energy-302671589.html
SOURCE IsoEnergy Ltd.
View original content to download multimedia: http://www.newswire.ca/en/releases/archive/January2026/27/c6827.html
%CIK: 0001997377
For further information: For further information, please contact:
IsoEnergy Ltd., Philip Williams, CEO and Director, (833) 572-2333, info@isoenergy.ca
CO: IsoEnergy Ltd.
CNW 13:30e 27-JAN-26