STOCK TITAN

BVF group sells 1,630,658 Kymera (KYMR) shares in joint Form 4

Filing Impact
(Very High)
Filing Sentiment
(Very Negative)
Form Type
4

Rhea-AI Filing Summary

Funds affiliated with BVF Partners reported significant stock sales in Kymera Therapeutics, Inc. common shares. On 2026-06-26, Section 13(d) group members filed a joint Form 4 showing open-market sales totaling 1,630,658 shares of Kymera common stock at $106.50 per share, split between direct and indirect holdings.

The filing also lists a series of vested and time-based stock options, with exercise prices ranging from $14.18 to $99.87 per share and expirations from 2030 to 2036, held indirectly through BVF-managed entities. In addition, the group retains several pre-funded warrants exercisable at $0.0001 per share that, according to the disclosure, are exercisable at any time and do not expire. Collectively, these derivatives indicate that BVF-affiliated vehicles remain substantial economic holders of Kymera beyond the reported common share sales.

Positive

  • None.

Negative

  • None.

Insights

BVF-affiliated funds disclosed a sizable net sale of Kymera shares while retaining large derivative exposure.

The joint Form 4 for Kymera Therapeutics (KYMR) shows BVF-related funds completing open-market sales of 1,630,658 common shares at $106.50 per share on June 26, 2026. The transactions are split between direct and indirect holdings across multiple partnership and fund entities within a Section 13(d) group.

Alongside the sales, the filing lists remaining stock options and pre-funded warrants over hundreds of thousands of underlying shares, with option strike prices from $14.18 to $99.87 and expirations out to 2036. Footnotes clarify layered beneficial ownership and pecuniary-interest arrangements, emphasizing that various BVF vehicles and principals "may be deemed" to beneficially own the securities.

Because the document does not quantify Kymera’s total shares outstanding, the proportion of holdings sold versus retained cannot be inferred here. The combination of a net-sell event with substantial continuing equity and derivative positions suggests portfolio rebalancing or profit-taking rather than a clearly directional change in overall exposure based solely on this disclosure.

Insider BVF PARTNERS L P/IL, BIOTECHNOLOGY VALUE FUND L P, BVF I GP LLC, BIOTECHNOLOGY VALUE FUND II LP, BVF II GP LLC, Biotechnology Value Trading Fund OS LP, BVF Partners OS Ltd., BVF GP HOLDINGS LLC, BVF INC/IL, LAMPERT MARK N
Role null | null | null | null | null | null | null | null | null | null
Sold 1,630,658 shs ($173.67M)
Type Security Shares Price Value
Sale Common Stock, $0.0001 par value 837,914 $106.50 $89.24M
Sale Common Stock, $0.0001 par value 627,597 $106.50 $66.84M
Sale Common Stock, $0.0001 par value 113,289 $106.50 $12.07M
Sale Common Stock, $0.0001 par value 51,858 $106.50 $5.52M
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Pre-Funded Warrants to Purchase Common Stock -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
holding Stock Option (Right to Buy) -- -- --
Holdings After Transaction: Common Stock, $0.0001 par value — 1,960,881 shares (Direct, null); Common Stock, $0.0001 par value — 78,787 shares (Indirect, See footnote); Pre-Funded Warrants to Purchase Common Stock — 201,546 shares (Direct, null); Pre-Funded Warrants to Purchase Common Stock — 27,797 shares (Indirect, See footnote); Stock Option (Right to Buy) — 40,127 shares (Indirect, See footnote)
Footnotes (1)
  1. This Form 4 is filed jointly by Biotechnology Value Fund, L.P. ("BVF"), Biotechnology Value Fund II, L.P. ("BVF2"), Biotechnology Value Trading Fund OS LP ("Trading Fund OS"), BVF Partners OS Ltd. ("Partners OS"), BVF I GP LLC ("BVF GP"), BVF II GP LLC ("BVF2 GP"), BVF GP Holdings LLC ("BVF GPH"), BVF Partners L.P. ("Partners"), BVF Inc. and Mark N. Lampert (collectively, the "Reporting Persons"). Each of the Reporting Persons is a member of a Section 13(d) group. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein. Securities owned directly by BVF. As the general partner of BVF, BVF GP may be deemed to beneficially own the securities owned directly by BVF. As the sole member of BVF GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF. As the investment manager of BVF, Partners may be deemed to beneficially own the securities owned directly by BVF. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF. Securities owned directly by BVF2. As the general partner of BVF2, BVF2 GP may be deemed to beneficially own the securities owned directly by BVF2. As the sole member of BVF2 GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF2. As the investment manager of BVF2, Partners may be deemed to beneficially own the securities owned directly by BVF2. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF2. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF2. Securities owned directly by Trading Fund OS. As the general partner of Trading Fund OS, Partners OS may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment manager of Trading Fund OS and the sole member of Partners OS, Partners may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by Trading Fund OS. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by Trading Fund OS. Securities held in a certain Partners managed account (the "Partners Managed Account"). Partners may be deemed to have indirect beneficial ownership of the securities of the Issuer held by the Partners Managed Account for purposes of Rule 16a-1(a)(2) because the securities account for more than 10% of the market value of the portfolio of the Partners Managed Account as of the reporting date. Partners, as the investment manager of the Partners Managed Account, may be deemed to beneficially own the securities held by the Partners Managed Account. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities held by the Partners Managed Account. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities held by the Partners Managed Account. The Pre-Funded Warrants are exercisable at any time after the date of issuance, subject to certain conditions and limitations, and do not expire. Partners, BVF Inc. and Mr. Lampert may be deemed to have a pecuniary interest in the securities reported owned herein due to a certain agreement between Partners and Gorjan Hrustanovic, who serves on the Issuer's board of directors and as a member of Partners, pursuant to which Mr. Hrustanovic is obligated to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the securities reported owned herein to Partners. As such, Mr. Hrustanovic disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein. The shares subject to the option have fully vested. The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.
Net common shares sold 1,630,658 shares Aggregate open-market or private sales reported for 2026-06-26
Reported sale price $106.50 per share Price for each Kymera common share sold on 2026-06-26
Indirect common shares after sale 78,787 shares Indirect holding total following one reported sale row
Direct common shares after sale 1,960,881 shares Direct holding total following one reported sale row
Largest direct pre-funded warrant position 550,425 underlying shares Pre-funded warrants exercisable at $0.0001 with no expiration
Highest option exercise price $99.87 per share Stock option over 6,068 shares expiring 2036-06-23
Lowest option exercise price $14.18 per share Stock option over 12,000 shares expiring 2032-06-14
Sell transactions count 4 sales Number of S-code open-market sale entries in the filing
Pre-Funded Warrants to Purchase Common Stock financial
"The Pre-Funded Warrants are exercisable at any time after the date of issuance, subject to certain conditions and limitations, and do not expire."
Section 13(d) group regulatory
"Each of the Reporting Persons is a member of a Section 13(d) group."
beneficial ownership financial
"Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein."
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.
pecuniary interest financial
"Partners, BVF Inc. and Mr. Lampert may be deemed to have a pecuniary interest in the securities reported owned herein due to a certain agreement between Partners and Gorjan Hrustanovic..."
Stock Option (Right to Buy financial
"Stock Option (Right to Buy) ... The shares subject to the option have fully vested."
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
BVF PARTNERS L P/IL

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Kymera Therapeutics, Inc. [ KYMR ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/26/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, $0.0001 par value(1)06/26/2026S837,914D$106.51,960,881D(2)
Common Stock, $0.0001 par value(1)06/26/2026S627,597D$106.51,592,261D(3)
Common Stock, $0.0001 par value(1)06/26/2026S113,289D$106.5240,123D(4)
Common Stock, $0.0001 par value(1)06/26/2026S51,858D$106.578,787I(5)See footnote(5)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value201,546201,546D(2)
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value156,742156,742D(3)
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value550,425550,425D(2)
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value375,856375,856D(3)
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value52,73352,733D(4)
Pre-Funded Warrants to Purchase Common Stock(1)$0.0001 (6) (6)Common Stock, $0.0001 par value27,79727,797I(5)See footnote(5)
Stock Option (Right to Buy)(7)$20 (8)08/19/2030Common Stock, $0.0001 par value40,12740,127I(7)See footnote(7)
Stock Option (Right to Buy)(7)$49.1 (8)06/15/2031Common Stock, $0.0001 par value20,06320,063I(7)See footnote(7)
Stock Option (Right to Buy)(7)$14.18 (8)06/14/2032Common Stock, $0.0001 par value12,00012,000I(7)See footnote(7)
Stock Option (Right to Buy)(7)$27.67 (8)06/14/2033Common Stock, $0.0001 par value12,00012,000I(7)See footnote(7)
Stock Option (Right to Buy)(7)$31.2 (8)06/17/2034Common Stock, $0.0001 par value16,00016,000I(7)See footnote(7)
Stock Option (Right to Buy)(7)$46.47 (8)06/24/2035Common Stock, $0.0001 par value16,00016,000I(7)See footnote(7)
Stock Option (Right to Buy)(7)$99.87 (9)06/23/2036Common Stock, $0.0001 par value6,0686,068I(7)See footnote(7)
1. Name and Address of Reporting Person*
BVF PARTNERS L P/IL

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BIOTECHNOLOGY VALUE FUND L P

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BVF I GP LLC

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BIOTECHNOLOGY VALUE FUND II LP

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BVF II GP LLC

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
Biotechnology Value Trading Fund OS LP

(Last)(First)(Middle)
P.O. BOX 309 UGLAND HOUSE

(Street)
GRAND CAYMANKY1-1104

(City)(State)(Zip)

CAYMAN ISLANDS

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BVF Partners OS Ltd.

(Last)(First)(Middle)
P.O. BOX 309 UGLAND HOUSE

(Street)
GRAND CAYMANKY1-1104

(City)(State)(Zip)

CAYMAN ISLANDS

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BVF GP HOLDINGS LLC

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
BVF INC/IL

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
1. Name and Address of Reporting Person*
LAMPERT MARK N

(Last)(First)(Middle)
44 MONTGOMERY STREET
40TH FLOOR

(Street)
SAN FRANCISCO CALIFORNIA 94104

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirector10% Owner
Officer (give title below)XOther (specify below)
See Remarks and Footnotes
Explanation of Responses:
1. This Form 4 is filed jointly by Biotechnology Value Fund, L.P. ("BVF"), Biotechnology Value Fund II, L.P. ("BVF2"), Biotechnology Value Trading Fund OS LP ("Trading Fund OS"), BVF Partners OS Ltd. ("Partners OS"), BVF I GP LLC ("BVF GP"), BVF II GP LLC ("BVF2 GP"), BVF GP Holdings LLC ("BVF GPH"), BVF Partners L.P. ("Partners"), BVF Inc. and Mark N. Lampert (collectively, the "Reporting Persons"). Each of the Reporting Persons is a member of a Section 13(d) group. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein except to the extent of his or its pecuniary interest therein.
2. Securities owned directly by BVF. As the general partner of BVF, BVF GP may be deemed to beneficially own the securities owned directly by BVF. As the sole member of BVF GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF. As the investment manager of BVF, Partners may be deemed to beneficially own the securities owned directly by BVF. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF.
3. Securities owned directly by BVF2. As the general partner of BVF2, BVF2 GP may be deemed to beneficially own the securities owned directly by BVF2. As the sole member of BVF2 GP, BVF GPH may be deemed to beneficially own the securities owned directly by BVF2. As the investment manager of BVF2, Partners may be deemed to beneficially own the securities owned directly by BVF2. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by BVF2. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by BVF2.
4. Securities owned directly by Trading Fund OS. As the general partner of Trading Fund OS, Partners OS may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment manager of Trading Fund OS and the sole member of Partners OS, Partners may be deemed to beneficially own the securities owned directly by Trading Fund OS. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities owned directly by Trading Fund OS. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities owned directly by Trading Fund OS.
5. Securities held in a certain Partners managed account (the "Partners Managed Account"). Partners may be deemed to have indirect beneficial ownership of the securities of the Issuer held by the Partners Managed Account for purposes of Rule 16a-1(a)(2) because the securities account for more than 10% of the market value of the portfolio of the Partners Managed Account as of the reporting date. Partners, as the investment manager of the Partners Managed Account, may be deemed to beneficially own the securities held by the Partners Managed Account. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the securities held by the Partners Managed Account. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the securities held by the Partners Managed Account.
6. The Pre-Funded Warrants are exercisable at any time after the date of issuance, subject to certain conditions and limitations, and do not expire.
7. Partners, BVF Inc. and Mr. Lampert may be deemed to have a pecuniary interest in the securities reported owned herein due to a certain agreement between Partners and Gorjan Hrustanovic, who serves on the Issuer's board of directors and as a member of Partners, pursuant to which Mr. Hrustanovic is obligated to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the securities reported owned herein to Partners. As such, Mr. Hrustanovic disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein.
8. The shares subject to the option have fully vested.
9. The shares underlying this stock option shall vest in full upon the earlier to occur of (i) June 24, 2027 and (ii) the date of the next annual meeting of the Issuer's stockholders.
Remarks:
For purposes of Section 16 of the Securities Exchange Act of 1934, as amended, each of the Reporting Persons may be deemed to be a director by deputization of the Issuer due to a member of Partners, Gorjan Hrustanovic, serving on the Board of Directors of the Issuer, and his agreement to transfer the economic benefit, if any, received upon the sale of the shares issuable upon exercise of the securities reported owned herein to Partners.
BVF Partners L.P., By: BVF Inc., its general partner, By: /s/ Mark N. Lampert, President06/26/2026
Biotechnology Value Fund, L.P., By: BVF I GP LLC, its general partner, By: /s/ Mark N. Lampert, Chief Executive Officer06/26/2026
BVF I GP LLC, By: /s/ Mark N. Lampert, Chief Executive Officer06/26/2026
Biotechnology Value Fund II, L.P., By: BVF II GP LLC, its general partner, By: /s/ Mark N. Lampert, Chief Executive Officer06/26/2026
BVF II GP LLC, By: /s/ Mark N. Lampert, Chief Executive Officer06/26/2026
BVF Partners OS Ltd., By: BVF Partners L.P., its sole member, By: BVF Inc., its general partner, By: /s/ Mark N. Lampert, President06/26/2026
Biotechnology Value Trading Fund OS LP, By: BVF Partners L.P., its investment manager, BVF Inc., its general partner, By: /s/ Mark N. Lampert, President06/26/2026
BVF GP Holdings LLC, By: /s/ Mark N. Lampert, Chief Executive Officer06/26/2026
BVF Inc., By: /s/ Mark N. Lampert, President06/26/2026
/s/ Mark N. Lampert06/26/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

How many Kymera Therapeutics (KYMR) shares did BVF-affiliated funds sell?

BVF-affiliated funds reported selling 1,630,658 Kymera Therapeutics common shares. These were open-market or private transactions at a reported sale price of $106.50 per share, executed on June 26, 2026, across both direct and indirect ownership entities within a Section 13(d) group.

Do BVF-affiliated holders still retain Kymera (KYMR) common stock after these sales?

Yes. Individual transaction rows show remaining direct and indirect common stock positions after each sale, including 78,787 shares in one indirect account and 1,960,881 shares in one direct account. These figures are per-entity post-transaction holdings and indicate continuing equity exposure to Kymera Therapeutics.

What stock options over Kymera (KYMR) shares are reported in this Form 4?

The filing lists several stock options over Kymera common stock held indirectly by BVF-managed entities. Underlying share amounts range from 6,068 to 40,127, with exercise prices between $14.18 and $99.87, and expiration dates spanning from 2030 through 2036, providing long-dated upside exposure.

What are the terms of the pre-funded warrants reported for Kymera (KYMR)?

The pre-funded warrants are exercisable into Kymera common stock at an exercise price of $0.0001 per share. Footnote F6 states they are exercisable at any time after issuance, subject to conditions and limitations, and that they do not expire, giving holders enduring low-cost conversion rights.

Who are the reporting persons in this Kymera (KYMR) Form 4 filing?

Reporting persons include multiple BVF entities—such as Biotechnology Value Fund, L.P., Biotechnology Value Fund II, L.P., Biotechnology Value Trading Fund OS LP, BVF Partners L.P., BVF Inc., and Mark N. Lampert. Footnote F1 notes they form a Section 13(d) group and disclaim beneficial ownership beyond pecuniary interests.