LENZ Therapeutics, Inc. shows multiple Squarepoint entities reporting beneficial ownership stakes in its common stock. Squarepoint Ops LLC, Squarepoint Capital LLP, Squarepoint Operations Private Limited and Squarepoint (DIFC) Ltd each report 1,593,246 shares (5.08%). Squarepoint Master Fund Limited reports 1,590,333 shares (5.07%) and Squarepoint Core Master Fund Limited reports 2,913 shares (0.01%).
The filing lists shared voting and shared dispositive power for these holdings and is signed by John Weitzer, Chief Compliance Officer, with signature dates of 04/08/2026.
Four Squarepoint affiliates each report 1,593,246 shares representing 5.08% of the class, while a Master Fund reports 1,590,333 shares (5.07%) and a Core Master Fund reports 2,913 shares (0.01%), all with shared voting and dispositive power as of the filing.
Such Schedule 13G filings typically reflect passive institutional positions; subsequent filings would show any change in intent or active engagement. Future SEC forms would show material shifts.
Key Figures
Shares reported (multiple entities):1,593,246 sharesPercent of class (per-entity):5.08%Shares reported (Master Fund):1,590,333 shares+3 more
Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.
shared dispositive powerregulatory
"Shared Dispositive Power 1,593,246.00"
Schedule 13Gregulatory
"form_type: SCHEDULE 13G"
A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
LENZ Therapeutics, Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
52635N103
(CUSIP Number)
04/01/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint Ops LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,593,246.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,593,246.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,593,246.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.1 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint Capital LLP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED KINGDOM
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,593,246.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,593,246.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,593,246.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.1 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint Operations Private Limited
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
SINGAPORE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,593,246.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,593,246.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,593,246.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.1 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint (DIFC) Ltd
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED ARAB EMIRATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,593,246.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,593,246.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,593,246.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.1 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint Master Fund Limited
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,590,333.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,590,333.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,590,333.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
5.1 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
CUSIP Number(s):
52635N103
1
Names of Reporting Persons
Squarepoint Core Master Fund Limited
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,913.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,913.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,913.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
0.0 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
LENZ Therapeutics, Inc.
(b)
Address of issuer's principal executive offices:
201 LOMAS SANTA FE DRIVE, SUITE 300, SOLANA BEACH, CALIFORNIA, 92075.
Item 2.
(a)
Name of person filing:
Squarepoint Ops LLC
Squarepoint Capital LLP
Squarepoint Operations Private Limited
Squarepoint (DIFC) Limited
Squarepoint Master Fund Limited
Squarepoint Core Master Fund Limited
(b)
Address or principal business office or, if none, residence:
Squarepoint Ops LLC
Squarepoint Master Fund Limited
Squarepoint Core Master Fund Limited
250 W 55th Street 32nd Floor, New York, NY 10019 USA
Squarepoint Capital LLP
Citypoint, One Ropemaker Street, London, EC2Y 9AW UK
Squarepoint Operations Private Limited
88 Market Street, CapitaSpring, Level 49, 048948 Singapore
Squarepoint (DIFC) Limited
Unit L29-07, Level 29, ICD Brookfield Place, Dubai International Financial Centre, Dubai,
United Arab Emirates
(c)
Citizenship:
Squarepoint Ops LLC- USA
Squarepoint Capital LLP- United Kingdom
Squarepoint Operations Private Limited- Singapore
Squarepoint (DIFC) Limited- United Arab Emirates
Squarepoint Master Fund Limited- Cayman Islands
Squarepoint Core Master Fund Limited- Cayman Islands
(d)
Title of class of securities:
Common Stock
(e)
CUSIP Number(s):
52635N103
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913
(b)
Percent of class:
Squarepoint Ops LLC- 5.08%
Squarepoint Capital LLP- 5.08%
Squarepoint Operations Private Limited- 5.08%
Squarepoint (DIFC) Limited- 5.08%
Squarepoint Master Fund Limited- 5.07%
Squarepoint Core Master Fund Limited- 0.01%
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
0
(ii) Shared power to vote or to direct the vote:
Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913
(iii) Sole power to dispose or to direct the disposition of:
0
(iv) Shared power to dispose or to direct the disposition of:
Squarepoint Ops LLC- 1,593,246
Squarepoint Capital LLP- 1,593,246
Squarepoint Operations Private Limited- 1,593,246
Squarepoint (DIFC) Limited- 1,593,246
Squarepoint Master Fund Limited- 1,590,333
Squarepoint Core Master Fund Limited- 2,913
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
What stakes did Squarepoint report in LENZ (LENZ)?
Squarepoint affiliates reported holdings including 1,593,246 shares (5.08%) for four entities and 1,590,333 shares (5.07%) for the Master Fund, plus 2,913 shares (0.01%). These figures appear in Item 4 of the Schedule 13G.
Does the Schedule 13G show voting control by Squarepoint in LENZ?
The filing shows shared voting power and shared dispositive power for the reported shares. It lists zero sole voting or sole dispositive power and indicates coordinated, not sole, control over votes.
Who signed the Schedule 13G for the Squarepoint entities?
The Schedule 13G is signed by John Weitzer, Chief Compliance Officer, for the Squarepoint entities. Signature dates shown on the filing are 04/08/2026 for each signature line.
What does 5.08% ownership mean for LENZ shareholders?
A 5.08% stake signals an institutional passive holding size under the Schedule 13G disclosure threshold; the filing reports percentages and shared powers but does not state any active control or intent to influence management.
When would Squarepoint need to change this filing type or update disclosures?
If the position becomes active or ownership crosses regulatory thresholds requiring different reporting, Squarepoint would move from Schedule 13G to other forms. The filing itself does not specify future timing; updates appear in subsequent SEC filings.
