Welcome to our dedicated page for MBX Biosciences SEC filings (Ticker: MBX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The MBX Biosciences, Inc. (Nasdaq: MBX) SEC filings page on Stock Titan provides access to the company’s regulatory disclosures as filed with the U.S. Securities and Exchange Commission. As a clinical-stage biopharmaceutical company and emerging growth company, MBX uses filings such as Forms S-1, 10-K, 10-Q, and 8-K to describe its Precision Endocrine Peptide™ (PEP™) platform, clinical programs, risk factors, and capital-raising activities.
In its S-1 registration statement, MBX outlines its focus on novel precision peptide therapies for endocrine and metabolic disorders and details key product candidates, including canvuparatide (MBX 2109) for chronic hypoparathyroidism, imapextide (MBX 1416) for post-bariatric hypoglycemia, and MBX 4291 for obesity. Subsequent 8-K filings report material events such as topline results from the Phase 2 Avail™ trial of canvuparatide, initiation of the Phase 1 trial of MBX 4291, public equity offerings, and changes in board and committee roles.
Through this page, users can review MBX’s periodic financial reports, which discuss research and development spending, cash and marketable securities, and expectations about funding operations, as well as prospectus materials that describe intended uses of offering proceeds. Form 8-K filings also summarize key clinical data, trial designs, and future development plans for the company’s programs.
Stock Titan enhances these filings with AI-powered summaries that highlight the main points of lengthy documents, helping readers quickly understand topics such as clinical results, financing terms, and governance updates. Real-time updates from EDGAR, along with structured access to material event reports and registration statements, make this page a central resource for analyzing MBX’s regulatory and financial disclosures.
MBX Biosciences’ shareholder OrbiMed has updated its ownership position after recent share sales and dilution. OrbiMed Advisors LLC and affiliated funds now report beneficial ownership of 3,637,887 MBX common shares, representing 7.7% of the class based on 47,153,288 shares outstanding.
OrbiMed Capital GP VII LLC is general partner of OrbiMed Private Investments VII, LP, which holds 2,958,000 shares, or 6.3% of outstanding shares. OrbiMed Genesis GP LLC is general partner of OrbiMed Genesis Master Fund, L.P., which holds 679,887 shares, or 1.4% of outstanding shares.
The amendment notes OrbiMed’s percentage ownership fell by more than 1% due to an increase in MBX shares outstanding and reports multiple open-market sales by the Genesis and OPI VII funds in late 2025 and early 2026 at prices between $31.03 and $42.09 per share.
MBX Biosciences received an amended Schedule 13G/A reporting a significant institutional holding by Wellington-affiliated entities. Wellington Management Group LLP and related entities report beneficial ownership of 3,349,961 shares of MBX Biosciences common stock, representing 7.46% of the class as of 12/31/2025.
The shares are held of record by clients of Wellington investment advisers, which share voting and dispositive power over the securities. No single client is known to hold more than five percent of the class. Wellington certifies the position is held in the ordinary course of business and not to change or influence control.
MBX Biosciences, Inc. closed an at-the-market stock sale, issuing 2,250,986 shares of common stock at a volume weighted average price of $38.76 per share for gross proceeds of approximately $87.1 million. The shares were sold through Jefferies under an existing Open Market Sale Agreement and shelf registration on Form S-3.
The company currently plans to use the net proceeds to fund clinical-stage programs, discovery research and development, additional clinical development, and general corporate purposes including working capital and capital expenditures. MBX Biosciences may also use some proceeds and existing cash to in-license, acquire, or invest in complementary businesses or technologies, and still has capacity to sell up to an additional $62.9 million of common stock under the same program.
MBX Biosciences Chief Medical Officer Azoulay Salomon reported new equity compensation. On February 2, 2026, Salomon received 15,000 shares of common stock, representing a grant of restricted stock units that vest over four years in equal quarterly installments, conditioned on continued service.
On the same date, Salomon was also granted a stock option for 70,000 shares of common stock with an exercise price of $39.07 per share. These options vest and become exercisable in 48 equal monthly installments beginning on March 2, 2026, also subject to continued service. Following these grants, Salomon beneficially owns 15,000 common shares and 70,000 derivative securities directly.
MBX Biosciences, Inc.’s Chief Financial Officer Richard Bartram received new equity awards in the form of restricted stock units and stock options. On February 2, 2026, he was granted 15,000 shares of common stock as RSUs at a price of $0 per share, all held directly after the grant.
He was also granted a stock option to buy 70,000 shares of common stock with an exercise price of $39.07 per share. These options vest and become exercisable in 48 equal monthly installments beginning on March 2, 2026, while the 15,000 RSUs vest in equal quarterly installments over four years. All vesting is conditioned on his continued service with the company.
MBX Biosciences President & CEO P. Kent Hawryluk reported new equity awards. On February 2, 2026, he received 35,250 shares of common stock in the form of restricted stock units at $0 per share, bringing his directly held common stock to 699,506 shares.
He was also granted a stock option to buy 164,500 shares of common stock at an exercise price of $39.07 per share, expiring on February 2, 2036, vesting in 48 equal monthly installments starting March 2, 2026. In addition, 468,277 shares are held indirectly by the P. Kent Hawryluk Revocable Trust, for which he serves as trustee.
MBX Biosciences granted director Laurie Stelzer stock options covering 32,000 shares of common stock on January 20, 2026. These options have an exercise price of $43.14 per share and are held as a direct ownership position.
One-third of the underlying shares will vest and become exercisable on January 20, 2027, the first anniversary of the grant date, with the remaining two-thirds vesting monthly over the following two years, subject to her continued service. After this grant, she beneficially owns 32,000 derivative securities linked to MBX Biosciences common stock.
MBX Biosciences director files initial ownership report with no holdings
MBX Biosciences, Inc. director Laurie Stelzer filed an initial Form 3 ownership report related to an event dated 01/20/2026. The filing identifies Stelzer as a director of MBX Biosciences and indicates that no non-derivative or derivative securities of the company are beneficially owned. The remarks section explicitly states that no securities are beneficially owned, confirming there are currently no reported MBX Biosciences shares or derivative instruments held by this reporting person.
MBX Biosciences, Inc. announced that its board of directors has appointed Laurie Stelzer as a new independent director, effective January 20, 2026. She was designated as a Class I director and will serve until the company’s 2028 annual meeting of stockholders, then continue until a successor is elected and qualified or until an earlier departure.
With her addition, the board size is set at eight directors, and she fills an existing vacancy. As a non-employee director, she will receive the same compensation as other non-employee directors under the company’s disclosed director compensation policy, and she will enter into the standard indemnification agreement used for other directors.
Ms. Stelzer has also been appointed to serve as a member and chairperson of the Audit Committee, replacing Ed Mathers on that committee, and will serve on the Compensation Committee. The compositions of the Nominating and Corporate Governance Committee and the Science and Medicine Committee remain unchanged.
MBX Biosciences Inc reported that BlackRock, Inc. has filed a Schedule 13G showing a significant passive ownership position in its common stock. As of the event date of 12/31/2025, BlackRock beneficially owned 2,271,161 MBX shares, representing 5.1% of the outstanding common stock.
BlackRock reports sole voting power over 2,244,877 shares and sole dispositive power over 2,271,161 shares, with no shared voting or dispositive power. The filing explains that this ownership is aggregated from certain BlackRock business units, and that various underlying clients have rights to dividends or sale proceeds, with no single client holding more than five percent of MBX’s outstanding common shares.
BlackRock certifies that the shares were acquired and are held in the ordinary course of business and not for the purpose of changing or influencing control of MBX Biosciences.