[Form 4] MeiraGTx Holdings plc Insider Trading Activity

Rhea-AI Filing Summary

Insider sale by a senior officer: Alexandria Forbes, listed as President & CEO and a director, reported a sale of 47,500 ordinary shares of MeiraGTx Holdings plc (MGTX) on 10/07/2025. The sales were executed under a pre-established Rule 10b5-1 trading plan adopted on 08/21/2024.

The filing shows a weighted average sales price of $8.39, with individual trade prices ranging from $8.23 to $8.53. Following the reported disposition, the reporting person beneficially owns 1,313,983 ordinary shares.

Positive

• Sale executed under a Rule 10b5-1 plan adopted on 08/21/2024
• Weighted average sale price disclosed at $8.39, with price range provided

Negative

• Senior executive sold 47,500 shares, reducing direct holdings
• Post-transaction beneficial ownership remains at 1,313,983 shares (potentially dilutive signal to some investors)

Insights

Corporate Governance Analyst

Pre-planned sale reduces headline concern but remains notable given role.

The sale was executed under a Rule 10b5-1 plan adopted on 08/21/2024, which indicates the transactions were pre-scheduled rather than opportunistic. That structure commonly aims to provide an affirmative defense against insider trading claims when properly adopted and followed.

Key dependencies include the plan's terms and any blackout restrictions; investors can request details about per-price execution from the reporting person as the filing notes. Near-term monitoring should focus on any additional Form 4 filings or modifications to the trading plan.

Insider Activity Specialist

Sale size, price range, and post-sale holdings are clearly disclosed.

The filing reports a 47,500 share disposition at a weighted average of $8.39, with prices between $8.23 and $8.53. The reporting person retains 1,313,983 shares after the transaction.

Because the filing commits to provide per-price breakdowns on request, interested parties can obtain exact execution details. Watch for further filings showing additional sales or plan terminations in the coming reporting periods.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Forbes Alexandria

(Last) (First) (Middle)

655 THIRD AVENUE

SUITE 1115

(Street)

NEW YORK NY 10017

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
MeiraGTx Holdings plc [ MGTX ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	PRESIDENT & CEO

3. Date of Earliest Transaction (Month/Day/Year)
10/07/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	10/07/2025		S(1)		47,500	D	$8.39(2)(3)	1,313,983	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 21, 2024.

2. The price reported reflects the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $8.23 to $8.53, inclusive.

3. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price.

	/s/ Richard Giroux, Attorney-in-Fact for Alexandria Forbes	10/07/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did the MeiraGTx (MGTX) Form 4 filed on 10/07/2025 disclose?

The filing shows Alexandria Forbes sold 47,500 ordinary shares on 10/07/2025 under a Rule 10b5-1 plan.

At what price were the MGTX shares sold?

The weighted average sales price was $8.39, with individual trades ranging from $8.23 to $8.53.

When was the 10b5-1 plan adopted for these transactions?

The trading plan was adopted on 08/21/2024 as stated in the filing.

How many MGTX shares does the reporting person own after the sale?

Following the reported transactions, the reporting person beneficially owns 1,313,983 ordinary shares.

Can investors obtain the exact per-price breakdown of the sales?

Yes. The reporting person states they will provide the number of shares sold at each separate price upon request to the SEC staff, the issuer, or a security holder.