[Form 4] MILESTONE SCIENTIFIC INC. Insider Trading Activity

Rhea-AI Filing Summary

Milestone Scientific (MLSS) reported insider stock sales. On 10/20/2025, the filer sold 24,034 shares of common stock at $0.4527, leaving 9,131,192 shares beneficially owned directly. On 10/21/2025, the filer sold an additional 40,000 shares at $0.4398, with 9,091,192 shares directly owned afterward.

The form was filed by one reporting person. The signature block shows /S/ Dr. Pedro Palau, Liquidator.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

BP4 S.r.l.

(Last) (First) (Middle)

CORSO VENEZIA 44

(Street)

MILAN, L6 20121

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
MILESTONE SCIENTIFIC INC. [ MLSS ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
10/20/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, Par Value $0.001	10/20/2025		S		24,034	D	$0.4527	9,131,192	D
Common Stock, Par Value $0.001	10/21/2025		S		40,000	D	$0.4398	9,091,192	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	/S/ Dr. Pedro Palau, Liquidator	10/23/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transactions did MLSS report?

The filer reported sales of 24,034 shares at $0.4527 on 10/20/2025 and 40,000 shares at $0.4398 on 10/21/2025.

How many MLSS shares did the filer hold after the transactions?

After the 10/20/2025 sale, 9,131,192 shares were directly owned; after the 10/21/2025 sale, 9,091,192 shares were directly owned.

Were the MLSS transactions under a Rule 10b5-1 plan?

The form includes the Rule 10b5-1 checkbox language, but no selection is indicated in the provided excerpt.

What security was involved in the MLSS insider trades?

The transactions involved Common Stock, par value $0.001.

How many reporting persons filed the MLSS Form 4?

It states Form filed by One Reporting Person.

Who signed the MLSS Form 4?

The signature line reads /S/ Dr. Pedro Palau, Liquidator with a date of 10/23/2025.