[Form 3] NEONC TECHNOLOGIES HOLDINGS, INC. Initial Statement of Beneficial Ownership

Rhea-AI Filing Summary

Neonc Technologies Holdings, Inc. director Ming-Fu (Alan) Chiang filed a Form 3 reporting his beneficial ownership of NTHI common stock. He directly holds 400,216 shares of common stock. He also reports indirect ownership of 29,309 shares through Orion Biomed Inc., 888,148 shares through NeuCen Biomedical Co. Ltd., 384,180 shares through HCWG LLC, and 488,196 shares held by certain family members. For the Orion, NeuCen, and family-held shares, he disclaims beneficial ownership except to the extent of any pecuniary interest, and the HCWG LLC position reflects only his 37.5% interest.

SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person^*

CHIANG MING-FU (ALAN)

(Last) (First) (Middle)

23975 SORRENTO PARK

SUITE 205

(Street)

CALABASAS CA 91302

(City) (State) (Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
11/12/2025

3. Issuer Name and Ticker or Trading Symbol
NEONC TECHNOLOGIES HOLDINGS, INC. [ NTHI ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	400,216	D
Common Stock	29,309(1)	I	By Orion Biomed Inc.
Common Stock	888,148(2)	I	By NeuCen Biomedical Co. Ltd.
Common Stock	384,180(3)	I	By HCWG LLC
Common Stock	488,196(4)	I	See footnote 4.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Such shares are owned by Orion Biomed Inc. ("Orion"). Orion is owned in part by Reporting Person, who disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein.

2. Shares held by NeuCen Biomedical Co. Ltd. ("NeuCen"). NeuCen is owned in part by Reporting Person's spouse. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein.

3. Such shares are held by virtue of beneficial ownership of HCWG LLC, a Delaware limited liability company. The shares represent only Reporting Person's 37.5% interest in HCWG.

4. Shares held by certain members of Reporting Person's family. Reporting Person disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest, if any, therein.

Remarks:

	/s/ Ming-Fu (Alan) Chiang	11/24/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did NTHI director Ming-Fu (Alan) Chiang report on this Form 3?

He reported his initial beneficial ownership of Neonc Technologies Holdings, Inc. common stock, including both direct and indirect holdings through entities and family members.

How many NTHI shares does Ming-Fu Chiang hold directly?

He reports 400,216 shares of NTHI common stock held in direct ownership.

What indirect NTHI holdings are reported through Orion Biomed Inc. and NeuCen Biomedical Co. Ltd.?

He reports 29,309 shares of NTHI common stock held through Orion Biomed Inc. and 888,148 shares held through NeuCen Biomedical Co. Ltd., with beneficial ownership disclaimed except for any pecuniary interest.

What is the nature of Ming-Fu Chiang’s interest in HCWG LLC’s NTHI shares?

He reports 384,180 shares of NTHI common stock held by virtue of beneficial ownership in HCWG LLC, representing only his 37.5% interest in that LLC.

Are any NTHI shares attributed to Ming-Fu Chiang’s family members?

Yes. He reports 488,196 shares of NTHI common stock held by certain family members and disclaims beneficial ownership except to the extent of any pecuniary interest.

Does this Form 3 involve any derivative securities for NTHI?

No derivative securities are listed; the Form 3 only shows non-derivative common stock holdings in Table I.