[Form 4] NEONC TECHNOLOGIES HOLDINGS, INC. Insider Trading Activity

Rhea-AI Filing Summary

Neonc Technologies Holdings, Inc. (NTHI) insider Amir F. Heshmatpour, a director, president and 10% owner, reported open-market purchases of the company’s common stock. On 11/21/2025 he bought 20,000 shares at $5.98 per share and another 4,000 shares at $6.50 per share, and on 11/24/2025 he bought 6,000 shares at $6.51 per share. Following these transactions, the form shows 2,992,000 shares held directly, which includes 275,000 shares held by certain immediate family members. It also reports indirect interests in 256,120 shares through HCWG LLC, 550,000 shares through KIG LLC, and 3,714,020 shares through AFH Holdings & Advisory, LLC, subject to the stated beneficial ownership disclaimers.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Heshmatpour Amir F

(Last) (First) (Middle)

23975 SORRENTO PARK

SUITE 205

(Street)

CALABASAS CA 91302

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
NEONC TECHNOLOGIES HOLDINGS, INC. [ NTHI ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	X	10% Owner
X	Officer (give title below)		Other (specify below)
	President

3. Date of Earliest Transaction (Month/Day/Year)
11/21/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
CommonStock	11/21/2025		P		20,000	A	$5.98	2,982,000(1)	D
Common Stock	11/21/2025		P		4,000	A	$6.5	2,986,000	D
Common Stock	11/24/2025		P		6,000	A	$6.51	2,992,000(1)	D
Common Stock								256,120(2)	I	By HCWG LLC
Common Stock								550,000(3)	I	By KIG LLC
Common Stock								3,714,020(4)	I	By AFH Holdings & Advisory, LLC.

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Includes 275,000 shares held by certain members of Reporting Person's immediate family of which Reporting Person disclaims beneficial ownership, except to the extent of his pecuniary interest, if any, therein.

2. Such shares represent only Reporting Person's proportionate interest in HCWG LLC.

3. Such shares are held by KIG LLC of which Reporting Person's spouse is the sole member. Reporting Person disclaims beneficial ownership of such shares except to the extent of his pecuniary interest, if any, therein.

4. Reporting Person is the sole member and manager of AFH Holding & Advisory, LLC.

Remarks:

	/S/ AMIR F HESHMATPOUR	11/24/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did NTHI insider Amir F. Heshmatpour report in this Form 4?

He reported open-market purchases of Neonc Technologies Holdings, Inc. (NTHI) common stock on 11/21/2025 and 11/24/2025, increasing his reported holdings.

How many NTHI shares did Amir F. Heshmatpour buy and at what prices?

He purchased 20,000 shares at $5.98, 4,000 shares at $6.50, and 6,000 shares at $6.51 per share.

What is the direct NTHI shareholding reported after these transactions?

The form reports 2,992,000 NTHI common shares held directly after the disclosed purchases, including 275,000 shares held by certain immediate family members.

What indirect NTHI holdings are disclosed for Amir F. Heshmatpour?

The filing lists indirect interests in 256,120 shares through HCWG LLC, 550,000 shares through KIG LLC, and 3,714,020 shares through AFH Holdings & Advisory, LLC, with beneficial ownership disclaimed as described.

What roles does Amir F. Heshmatpour hold at Neonc Technologies Holdings (NTHI)?

He is disclosed as a director, president, and 10% owner of Neonc Technologies Holdings, Inc.

Is this NTHI Form 4 filed by one or multiple reporting persons?

The form indicates it is filed by one reporting person, Amir F. Heshmatpour.