Welcome to our dedicated page for Intellia Therape SEC filings (Ticker: NTLA), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Intellia Therapeutics, Inc. (NASDAQ: NTLA) SEC filings page on Stock Titan provides access to the company’s regulatory disclosures, including Current Reports on Form 8-K that detail material events in its clinical and corporate development. As a clinical-stage gene editing company, Intellia uses SEC filings to report key information about its CRISPR-based programs, financial results and significant regulatory interactions.
Recent 8-K filings furnished by Intellia describe positive Phase 1 and Phase 1/2 data for its investigational in vivo CRISPR therapies, nexiguran ziclumeran (nex-z) for transthyretin (ATTR) amyloidosis and lonvoguran ziclumeran (lonvo-z) for hereditary angioedema (HAE). These filings summarize trial designs, patient numbers, biomarker reductions, clinical outcome measures and safety observations over multi-year follow-up. Other 8-Ks discuss the initiation and status of global Phase 3 trials such as MAGNITUDE, MAGNITUDE-2 and HAELO, as well as the FDA’s clinical hold on the MAGNITUDE programs for nex-z.
Intellia also uses Form 8-K to furnish quarterly financial results, including collaboration revenue, research and development expenses, general and administrative expenses and cash, cash equivalents and marketable securities. Additional filings report equity inducement grants made under the company’s 2024 Inducement Plan pursuant to Nasdaq Listing Rule 5635(c)(4), and changes involving senior executives.
On Stock Titan, these SEC filings are updated in near real time from EDGAR and can be paired with AI-powered summaries that highlight the most important points in dense regulatory documents. Users can quickly understand the implications of Intellia’s 8-K disclosures, track the evolution of its nex-z and lonvo-z programs, and monitor material events that may affect NTLA’s risk profile and development timeline.
Intellia Therapeutics executive James Basta reported a tax-related stock sale. On January 5, 2026, he sold 10,397 shares of Intellia Therapeutics common stock at a price of $9.21 per share. According to the filing, this was a mandatory “sell-to-cover” transaction to satisfy his tax withholding obligation from restricted stock units that vested on January 1, 2026, and it is explicitly described as not a voluntary trade. After this transaction, he beneficially owned 101,528 shares of Intellia common stock directly.
Intellia Therapeutics, Inc. director Fred E. Cohen reported an open market purchase of the company’s common stock. On January 5, 2026, he bought 150,000 shares of common stock at a weighted average price of $9.35 per share, coded as a purchase transaction.
According to the filing, these shares were acquired in multiple trades at prices ranging from $9.13 to $9.68. Following this transaction, Cohen beneficially owns 207,453 shares of Intellia Therapeutics common stock held directly.
Intellia Therapeutics EVP and Chief Medical Officer David Lebwohl reported a sale of common stock that was carried out solely to cover taxes on recently vested restricted stock units. On January 5, 2026, he sold 11,903 shares of Intellia Therapeutics common stock at $9.21 per share in a mandatory "sell-to-cover" transaction tied to RSUs that vested on January 1, 2026. After this transaction, Lebwohl beneficially owned 121,249 shares of Intellia common stock. This total includes 1,022 shares and 1,264 shares that were previously acquired through the company’s 2016 Employee Stock Purchase Plan on June 30, 2025 and December 31, 2025, respectively.
Intellia Therapeutics executive Eliana Clark reported an automatic share sale related to taxes. A Form 4 shows that on January 5, 2026, the EVP and Chief Technical Officer sold 9,515 shares of Intellia Therapeutics common stock at $9.21 per share. The filing explains this was a mandatory “sell-to-cover” transaction to satisfy her tax withholding obligation upon the vesting of restricted stock units on January 1, 2026, and does not represent a volitional trade by the reporting person.
After this transaction, she beneficially owns 87,118 shares of Intellia common stock, including 1,264 shares acquired under the company’s 2016 Employee Stock Purchase Plan on December 31, 2025.
Intellia Therapeutics EVP and CFO Edward J. Dulac III reported an automatic sale of company stock. On January 5, 2026, he sold 6,379 shares of Intellia Therapeutics common stock at a price of $9.21 per share. According to the disclosure, this was a mandatory “sell-to-cover” transaction to satisfy tax withholding obligations tied to restricted stock units that vested on January 1, 2026, and it is described as not being a voluntary trade by the executive. After this transaction, he beneficially owns 99,683 shares of Intellia Therapeutics common stock directly.
Intellia Therapeutics VP and Chief Accounting Officer Michael P. Dube reported a small insider stock sale linked to tax withholding. On January 5, 2026, he sold 2,989 shares of Intellia common stock at $9.21 per share, leaving him with 52,277 shares held directly after the transaction.
According to the footnote, this was a mandatory “sell-to-cover” transaction carried out to satisfy his tax withholding obligations arising from the vesting of restricted stock units (RSUs) on January 1, 2026. The disclosure states that this sale does not represent a voluntary trading decision by the reporting officer but an automatic sale tied to equity award taxation.
Intellia Therapeutics' President and CEO, who is also a director, reported stock option exercises and related share sales in company stock. On 12/11/2025, the reporting person exercised options to acquire 49,959 shares of common stock at an exercise price of $ 6.83 and sold 49,959, 32,832 and 5,355 shares in separate transactions with weighted average prices of $ 9.49, $ 9.47 and $ 9.59, respectively.
On 12/12/2025, additional options for 8,557 shares were exercised at $ 6.83. These option awards were granted under the company’s 2015 Stock Option and Incentive Plan and had vested in full as of 12/11/2025. The filing notes that the sales occurred automatically under a Rule 10b5‑1 trading plan adopted on 09/11/2025. Following these transactions, the reporting person beneficially owns 1,047,485 shares directly and 58,415 shares indirectly through the John M. Leonard 2015 Irrevocable Trust.
Intellia Therapeutics (NTLA) reported new clinical updates across two in vivo CRISPR programs. For hereditary angioedema, a pooled Phase 1/2 analysis of 32 patients receiving a one-time 50 mg dose of lonvoguran ziclumeran (lonvo-z) showed a mean 89% reduction in plasma kallikrein at month 24. 31 of 32 patients (97%) were attack-free and off long-term prophylaxis as of the August 29, 2025 cut-off, with a safety profile described as well tolerated up to three years of follow-up. The global Phase 3 HAELO trial completed enrollment in September 2025, with topline data expected by mid-2026.
For transthyretin amyloidosis with cardiomyopathy, the Phase 1 trial of nexiguran ziclumeran (nex-z) enrolled 36 patients and showed sustained serum TTR reduction; among nine patients at 36 months, the mean reduction was 87%. At 24 months, stability or improvement was seen in 70% (NT-proBNP), 85% (hs‑Troponin T), and 69% (6MWT), with 81% stable or improved NYHA class. A matched-cohort mortality analysis reported HR 0.27 (p=0.009). The FDA placed a clinical hold on the Phase 3 MAGNITUDE and MAGNITUDE‑2 trials on October 29, 2025.
Intellia Therapeutics (NTLA) reported Q3 2025 results showing collaboration revenue of $13,782 and a net loss of $101,324. Operating expenses fell year over year as research and development declined to $94,747 from $123,380, while general and administrative was essentially flat at $30,512. Other income, net, was $10,153, driven primarily by interest income.
Liquidity remained sizable with cash and cash equivalents of $193,389 and marketable securities of $476,469 as of September 30, 2025. Year to date, the company raised $128,175 through at-the-market share sales and ended the quarter with 115,787,285 shares outstanding; 115,829,926 shares were outstanding as of October 31, 2025. Stockholders’ equity was $748,422.
Strategic updates included a January workforce reduction of about 27% with $6,500 in restructuring charges. The company amended and partially terminated facility leases, paying $34,000 in February and $30,000 in April 2025, with $14,000 due in January 2026, and recorded $40,500 of prepaid rent tied to a new Tech Square lease. Collaboration activity included a $1,800 milestone recognized under the Regeneron agreements, termination of the ReCode agreement in September 2025, and termination of the SparingVision collaboration in October 2025 with the return of 50% of its Series A2 shares.
Intellia Therapeutics (NTLA) filed an 8-K announcing its financial results and business updates for the quarter ended September 30, 2025. The company furnished a press release as Exhibit 99.1 detailing the announcement.
The information provided under Item 2.02 is furnished, not deemed filed under Section 18 of the Exchange Act, and may be incorporated by reference only if a subsequent filing specifically references it.