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  4. [Form 4] Natera, Inc. Insider Trading Activity

Natera co-founder Jonathan Sheena sells 3,150 shares

The sales were made under a Rule 10b5-1 plan adopted December 12, 2025, while two trust holdings were reported with a beneficial-ownership disclaimer.

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Form Type
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Rhea-AI Filing Summary

Natera, Inc. (NTRA) director and co-founder Jonathan Sheena reported selling 3,150 common shares on November 6, 2026, in multiple transactions. The listed weighted-average prices for individual sale entries ranged from $304.5713 to $325.0509 per share; the sales were made under a Rule 10b5-1 trading plan adopted December 12, 2025. As of November 6, 2026, Caraluna 1 Trust and Caraluna 2 Trust each held 8,250 shares for beneficiaries, and Jonathan Sheena disclaimed beneficial ownership of those trust shares.

Insider Sheena Jonathan
Role Director
Sold 3,150 shs ($995K)
Type Security Shares Price Value
Sale Common Stock F1, F2, F3 15 $304.5713 $5K
Sale Common Stock F1, F4 51 $305.7527 $16K
Sale Common Stock F1, F5 21 $306.4633 $6K
Sale Common Stock F1, F6 50 $308.198 $15K
Sale Common Stock F1, F7 64 $309.0817 $20K
Sale Common Stock F1, F8 110 $310.1655 $34K
Sale Common Stock F1, F9 100 $311.3116 $31K
Sale Common Stock F1, F10 106 $312.1965 $33K
Sale Common Stock F1, F11 74 $313.3168 $23K
Sale Common Stock F1, F12 108 $314.7084 $34K
Sale Common Stock F1, F13 169 $315.4827 $53K
Sale Common Stock F1, F14 1,838 $316.8674 $582K
Sale Common Stock F1, F15 56 $318.1661 $18K
Sale Common Stock F1, F16 105 $319.2993 $34K
Sale Common Stock F1, F17 131 $320.0673 $42K
Sale Common Stock F1, F18 51 $321.1191 $16K
Sale Common Stock F1 16 $321.85 $5K
Sale Common Stock F1, F19 40 $323.859 $13K
Sale Common Stock F1, F20 45 $325.0509 $15K
Holding Common Stock F21 -- -- --
Holding Common Stock F21 -- -- --
Holdings After Transaction: Common Stock — 214,462 shares (Direct); Common Stock — 8,250 shares (Indirect, by Caraluna 1 Trust); Common Stock — 8,250 shares (Indirect, By Caraluna 2 Trust)
Footnotes (21)
  1. F1. The sale of shares was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2025.
  2. F2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.24 to $304.95 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  3. F3. Includes 38 shares acquired under the Issuer's 2015 Employee Stock Purchase Plan on October 31, 2026
  4. F4. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.30 to $306.24 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  5. F5. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.39 to $306.50 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  6. F6. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.70 to $308.54 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  7. F7. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $308.7200 to $309.6450 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  8. F8. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.81 to $310.66 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  9. F9. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.99 to $311.98 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  10. F10. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $312.00 to $312.46 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  11. F11. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.01 to $314.00 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  12. F12. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.04 to $315.01 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  13. F13. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $315.0900 to $316.0750 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  14. F14. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $316.24 to $317.14 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  15. F15. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $317.36 to $318.30 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  16. F16. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $318.67 to $319.66 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  17. F17. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $319.67 to $320.54 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  18. F18. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $320.77 to $321.63 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  19. F19. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $323.3800 to $324.3550 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  20. F20. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $324.56 to $325.53 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
  21. F21. Held for the benefit of the beneficiaries of the trust. The Reporting Person disclaims beneficial ownership over such securities.
Common shares sold 3,150 shares Reported for November 6, 2026
Lowest listed weighted-average sale price $304.5713 per share Individual sale entry reported for November 6, 2026
Highest listed weighted-average sale price $325.0509 per share Individual sale entry reported for November 6, 2026
Shares held by Caraluna 1 Trust 8,250 shares As of November 6, 2026; held for the benefit of trust beneficiaries
Shares held by Caraluna 2 Trust 8,250 shares As of November 6, 2026; held for the benefit of trust beneficiaries
Rule 10b5-1 trading plan regulatory
"pursuant to a Rule 10b5-1 trading plan adopted"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
weighted average price financial
"The reported price in Column 4 is a weighted average price."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
Employee Stock Purchase Plan financial
"acquired under the Issuer's 2015 Employee Stock Purchase Plan"
An employee stock purchase plan is a company program that lets workers buy shares through small payroll deductions, often at a discount to the market price and after a set offering period. Think of it like a workplace savings plan that turns into ownership: it encourages employees to share in the company’s success and can create predictable buying or selling of stock that investors watch because it affects supply, demand and employee incentives.
beneficial ownership regulatory
"The Reporting Person disclaims beneficial ownership"
Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many NTRA shares did director and co-founder Jonathan Sheena sell, and at what prices?
Jonathan Sheena reported selling 3,150 Natera common shares on November 6, 2026, in multiple transactions; the listed weighted-average prices ranged from $304.5713 to $325.0509 per share. The sales were made under a Rule 10b5-1 trading plan adopted December 12, 2025.

What NTRA shares were listed in trusts?
As of November 6, 2026, Caraluna 1 Trust and Caraluna 2 Trust each held 8,250 Natera common shares for beneficiaries; Jonathan Sheena disclaimed beneficial ownership of those securities.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →
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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Sheena Jonathan
(Last)(First)(Middle)
C/O NATERA, INC.
13011 MCCALLEN PASS BUILDING A SUITE 100
(Street)
AUSTIN TEXAS 78753
(City)(State)(Zip)
UNITED STATES
(Country)		2. Issuer Name and Ticker or Trading Symbol
Natera, Inc. [ NTRA ] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)XOther (specify below)
CO-FOUNDER
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
11/06/2026		6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock11/06/2026S15(1)D$304.5713(2)217,597(3)D
Common Stock11/06/2026S51(1)D$305.7527(4)217,546D
Common Stock11/06/2026S21(1)D$306.4633(5)217,525D
Common Stock11/06/2026S50(1)D$308.198(6)217,475D
Common Stock11/06/2026S64(1)D$309.0817(7)217,411D
Common Stock11/06/2026S110(1)D$310.1655(8)217,301D
Common Stock11/06/2026S100(1)D$311.3116(9)217,201D
Common Stock11/06/2026S106(1)D$312.1965(10)217,095D
Common Stock11/06/2026S74(1)D$313.3168(11)217,021D
Common Stock11/06/2026S108(1)D$314.7084(12)216,913D
Common Stock11/06/2026S169(1)D$315.4827(13)216,744D
Common Stock11/06/2026S1,838(1)D$316.8674(14)214,906D
Common Stock11/06/2026S56(1)D$318.1661(15)214,850D
Common Stock11/06/2026S105(1)D$319.2993(16)214,745D
Common Stock11/06/2026S131(1)D$320.0673(17)214,614D
Common Stock11/06/2026S51(1)D$321.1191(18)214,563D
Common Stock11/06/2026S16(1)D$321.85214,547D
Common Stock11/06/2026S40(1)D$323.859(19)214,507D
Common Stock11/06/2026S45(1)D$325.0509(20)214,462D
Common Stock8,250Iby Caraluna 1 Trust(21)
Common Stock8,250IBy Caraluna 2 Trust(21)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. The sale of shares was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2025.
2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $304.24 to $304.95 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
3. Includes 38 shares acquired under the Issuer's 2015 Employee Stock Purchase Plan on October 31, 2026
4. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $305.30 to $306.24 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
5. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $306.39 to $306.50 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
6. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $307.70 to $308.54 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
7. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $308.7200 to $309.6450 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
8. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $309.81 to $310.66 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
9. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $310.99 to $311.98 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
10. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $312.00 to $312.46 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
11. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $313.01 to $314.00 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
12. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $314.04 to $315.01 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
13. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $315.0900 to $316.0750 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
14. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $316.24 to $317.14 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
15. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $317.36 to $318.30 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
16. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $318.67 to $319.66 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
17. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $319.67 to $320.54 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
18. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $320.77 to $321.63 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
19. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $323.3800 to $324.3550 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
20. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $324.56 to $325.53 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
21. Held for the benefit of the beneficiaries of the trust. The Reporting Person disclaims beneficial ownership over such securities.
/s/ Tami Chen, Attorney-in-Fact11/10/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

Source: View Original Filing on SEC EDGAR

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