Natera co-founder Jonathan Sheena sells 3,150 shares

The Rule 10b5-1 trading plan under which the sales were made was adopted December 12, 2025.

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Rhea-AI Filing Summary

Natera, Inc. (NTRA) director and co-founder Jonathan Sheena sold 3,150 common shares across eight reported sale entries on October 21, 2026, at reported per-share prices ranging from $406.5000 to $416.6736. The sales were made under a Rule 10b5-1 trading plan adopted December 12, 2025. The filing also lists 8,250 shares held for beneficiaries of each of the Caraluna 1 Trust and Caraluna 2 Trust; Sheena disclaims beneficial ownership of those trust-held securities.

Insider Trade Summary 10b5-1

Net Seller: 3,150 shares

Net Sell 10 txns

Insider Sheena Jonathan

Role Director

Sold 3,150 shs ($1.29M)

Type	Security	Shares	Price	Value
Sale	Common Stock ^F1	200	$406.50	$81K
Sale	Common Stock ^{F1, F2}	962	$408.2584	$393K
Sale	Common Stock ^{F1, F3}	627	$409.8932	$257K
Sale	Common Stock ^{F1, F4}	605	$411.3175	$249K
Sale	Common Stock ^{F1, F5}	211	$412.1991	$87K
Sale	Common Stock ^{F1, F6}	125	$413.0476	$52K
Sale	Common Stock ^{F1, F7}	255	$415.6659	$106K
Sale	Common Stock ^{F1, F8}	165	$416.6736	$69K
holding	Common Stock ^F9	--	--	--
holding	Common Stock ^F9	--	--	--

Holdings After Transaction: Common Stock — 218,164 shares (Direct); Common Stock — 8,250 shares (Indirect, by Caraluna 1 Trust); Common Stock — 8,250 shares (Indirect, By Caraluna 2 Trust)

Footnotes (9)

F1. The sale of shares was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2025.
F2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $408.00 to $408.96 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F3. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $409.22 to $410.03 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F4. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $410.91 to $411.64 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F5. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $412.00 to $412.21 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F6. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $413.00 to $413.09 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F7. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $415.35 to $416.24 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F8. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $416.36 to $416.81 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
F9. Held for the benefit of the beneficiaries of the trust. The Reporting Person disclaims beneficial ownership over such securities.

Key Figures

Common shares sold: 3,150 shares Sale tranche: 200 shares at $406.5000 per share Sale tranche: 962 shares at $408.2584 per share +2 more

5 metrics

Common shares sold 3,150 shares Across eight reported sale entries on October 21, 2026

Sale tranche 200 shares at $406.5000 per share October 21, 2026

Sale tranche 962 shares at $408.2584 per share October 21, 2026

Sale tranche 165 shares at $416.6736 per share October 21, 2026

Shares held for beneficiaries 8,250 shares in each of Caraluna 1 Trust and Caraluna 2 Trust Trust-held shares listed in the filing

Key Terms

Rule 10b5-1 trading plan, weighted average price, beneficial ownership

3 terms

Rule 10b5-1 trading plan regulatory

"effected pursuant to a Rule 10b5-1 trading plan"

A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.

weighted average price financial

"is a weighted average price"

Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.

beneficial ownership financial

"disclaims beneficial ownership over such securities"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many NTRA shares did director and co-founder Jonathan Sheena sell, and at what prices?

Jonathan Sheena reported selling 3,150 common shares on October 21, 2026, across eight sale entries with reported per-share prices from $406.5000 to $416.6736. The entries list 200 shares at $406.5000, 962 at $408.2584, 627 at $409.8932, 605 at $411.3175, 211 at $412.1991, 125 at $413.0476, 255 at $415.6659, and 165 at $416.6736.

How many NTRA shares are held in the Caraluna trusts?

The filing lists 8,250 common shares held for the beneficiaries of Caraluna 1 Trust and 8,250 common shares held for the beneficiaries of Caraluna 2 Trust. Jonathan Sheena disclaims beneficial ownership of those securities.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →

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Available on EDGAR 10/23/2026 - 09:25 PM EDT Accepted by SEC EDGAR 10/23/2026 - 09:25 PM EDT

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Sheena Jonathan

(Last)

(First)

(Middle)

C/O NATERA, INC.

13011 MCCALLEN PASS BUILDING A SUITE 100

(Street)

AUSTIN

TEXAS

78753

(City)

(State)

(Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Natera, Inc. [ NTRA ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)	X	Other (specify below)
			CO-FOUNDER

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
10/21/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	10/21/2026		S		200⁽¹⁾	D	$406.5	221,114	D
Common Stock	10/21/2026		S		962⁽¹⁾	D	$408.2584⁽²⁾	220,152	D
Common Stock	10/21/2026		S		627⁽¹⁾	D	$409.8932⁽³⁾	219,525	D
Common Stock	10/21/2026		S		605⁽¹⁾	D	$411.3175⁽⁴⁾	218,920	D
Common Stock	10/21/2026		S		211⁽¹⁾	D	$412.1991⁽⁵⁾	218,709	D
Common Stock	10/21/2026		S		125⁽¹⁾	D	$413.0476⁽⁶⁾	218,584	D
Common Stock	10/21/2026		S		255⁽¹⁾	D	$415.6659⁽⁷⁾	218,329	D
Common Stock	10/21/2026		S		165⁽¹⁾	D	$416.6736⁽⁸⁾	218,164	D
Common Stock								8,250	I	by Caraluna 1 Trust⁽⁹⁾
Common Stock								8,250	I	By Caraluna 2 Trust⁽⁹⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)

Explanation of Responses:

1. The sale of shares was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 12, 2025.

2. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $408.00 to $408.96 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

3. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $409.22 to $410.03 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

4. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $410.91 to $411.64 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

5. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $412.00 to $412.21 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

6. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $413.00 to $413.09 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

7. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $415.35 to $416.24 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

8. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $416.36 to $416.81 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

9. Held for the benefit of the beneficiaries of the trust. The Reporting Person disclaims beneficial ownership over such securities.

	/s/ Tami Chen, Attorney-in-Fact	10/23/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

Source: View Original Filing on SEC EDGAR