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TPG funds take 7.8% Odyssey Therapeutics (ODTX) stake via $25M share purchase

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D

Rhea-AI Filing Summary

TPG-affiliated investors have disclosed a significant new stake in Odyssey Therapeutics, Inc. Funds managed through TPG GP A, LLC now beneficially own 3,690,146 shares of Odyssey common stock, representing about 7.8% of the 47,174,156 shares outstanding as of the IPO closing.

The position includes 1,388,889 shares that TPG LSI Rise Orazio II, L.P. bought directly from Odyssey for $25,000,002 in a concurrent private placement at $18.00 per share, matching the initial public offering price. An Investors' Rights Agreement grants registration rights for resale of these shares, and the filing notes TPG may later consider actions involving Odyssey's operations, capital structure or additional share transactions.

Positive

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Insights

TPG discloses a 7.8% Odyssey stake built partly through a $25M private purchase at the IPO price.

The filing shows TPG-controlled funds holding 3,690,146 Odyssey shares, or about 7.8% of the common stock, based on 47,174,156 shares outstanding as of the IPO closing. This includes 1,388,889 newly issued shares bought for $25,000,002 at $18.00 per share in a concurrent private placement.

An Amended and Restated Investors' Rights Agreement provides for registration of these shares for resale, giving TPG liquidity options. The narrative also leaves open the possibility of future proposals on strategy, capital structure, or additional share transactions, although no specific plans are currently stated in the excerpt.

Beneficial ownership 3,690,146 shares Shares of Odyssey common stock deemed beneficially owned by reporting persons
Ownership percentage 7.8% Portion of Odyssey common stock based on 47,174,156 shares outstanding at closing
Shares outstanding 47,174,156 shares Odyssey common stock outstanding as of IPO closing used for ownership calculation
Private placement shares 1,388,889 shares Shares issued to TPG LSI Rise Orazio II, L.P. in concurrent private placement
Private placement price $18.00 per share Price per share paid in concurrent private placement, equal to IPO price
Aggregate purchase price $25,000,002 Total paid by TPG LSI Rise Orazio II, L.P. for 1,388,889 shares
Shared voting power 3,690,146 shares Shares over which reporting persons report shared voting power
Shared dispositive power 3,690,146 shares Shares over which reporting persons report shared dispositive power
Schedule 13D regulatory
"If the filing person has previously filed a statement on Schedule 13G..."
A Schedule 13D is a legal document that investors file with regulators when they buy a large enough stake in a company to potentially influence its management or decisions. It provides details about the investor’s intention, ownership stake, and plans, helping other investors understand who is gaining control and what their motives might be.
beneficially own financial
"the Reporting Persons may be deemed to beneficially own 3,690,146 shares of Common Stock"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
Concurrent Private Placement financial
"at the $18.00 price per share... in the Issuer's initial public offering (the "Concurrent Private Placement")"
A concurrent private placement is a sale of a company’s shares or bonds directly to a select group of investors that happens at the same time as another financing action or offering. Think of it as quietly selling a block of tickets to a few people while a larger ticket drive is underway; it raises cash quickly but can change ownership proportions, dilute existing shareholders and affect share price, so investors watch it as a sign of funding needs and potential value shifts.
Share Purchase Agreement legal
"TPG Orazio II entered into a Share Purchase Agreement (the "Share Purchase Agreement")"
A share purchase agreement is a written contract that outlines the terms and conditions for buying and selling shares of a company. It specifies details like the price, number of shares, and any special conditions, ensuring both buyer and seller agree on the transaction. For investors, it provides clarity and legal protection, making sure the purchase is clear and enforceable.
Investors' Rights Agreement legal
"an Amended and Restated Investors' Rights Agreement (the "Investors' Rights Agreement") with the Issuer"
Rule 13d-3 regulatory
"Pursuant to Rule 13d-3 under the Act, the Reporting Persons may be deemed to beneficially own"
Rule 13d-3 defines who is treated as the beneficial owner of a company’s shares for U.S. securities disclosure rules — essentially anyone who has the power to vote or direct how shares are voted, or the power to buy or sell them, even if they don’t hold the certificates. For investors this matters because crossing certain ownership thresholds triggers public filing and disclosure obligations and signals potential control or influence, much like having the keys to a car implies you can drive it even if it’s registered to someone else.





67613T104

(CUSIP Number)
Jennifer L. Chu
301 Commerce Street, Suite 3300,
Fort Worth, TX, 76102
(817) 871-4000

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
05/11/2026

(Date of Event Which Requires Filing of This Statement)


If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




schemaVersion:


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage beneficial ownership set forth in response to Item 13 above is based on 47,174,156 shares of Common Stock (as defined below) outstanding as of Closing (as defined below), as reported in the Prospectus filed by the Issuer (as defined below) with the Securities and Exchange Commission (the "Commission") on May 8, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage beneficial ownership set forth in response to Item 13 above is based on 47,174,156 shares of Common Stock outstanding as of Closing, as reported in the Prospectus filed by the Issuer with the Commission on May 8, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage beneficial ownership set forth in response to Item 13 above is based on 47,174,156 shares of Common Stock outstanding as of Closing, as reported in the Prospectus filed by the Issuer with the Commission on May 8, 2026.


SCHEDULE 13D


TPG GP A, LLC
Signature:/s/ Matthew White
Name/Title:Matthew White / Vice President
Date:05/18/2026
James G. Coulter
Signature:/s/ Gerald Neugebauer
Name/Title:Gerald Neugebauer, on behalf of James G. Coulter (1)
Date:05/18/2026
Jon Winkelried
Signature:/s/ Gerald Neugebauer
Name/Title:Gerald Neugebauer, on behalf of Jon Winkelried (2)
Date:05/18/2026
Comments accompanying signature:
(1) Gerald Neugebauer is signing on behalf of Mr. Coulter pursuant to an authorization and designation letter dated January 10, 2024, which was previously filed with the Commission as an exhibit to a Form 4 filed by Mr. Coulter on February 7, 2024 (SEC File No. 001-41617). (2) Gerald Neugebauer is signing on behalf of Mr. Winkelried pursuant to an authorization and designation letter dated January 10, 2024, which was previously filed with the Commission as an exhibit to a Form 4 filed by Mr. Winkelried on February 7, 2024 (SEC File No. 001-41617).

FAQ

What percentage of Odyssey Therapeutics (ODTX) does TPG report owning in this Schedule 13D?

The reporting persons may be deemed to beneficially own 3,690,146 Odyssey shares, representing approximately 7.8% of the outstanding common stock. This percentage is based on 47,174,156 shares outstanding as of the IPO closing, as stated in the company’s prospectus.

How many Odyssey Therapeutics (ODTX) shares did TPG buy in the concurrent private placement and at what price?

TPG LSI Rise Orazio II, L.P. purchased 1,388,889 shares of Odyssey common stock in a concurrent private placement at $18.00 per share. The total purchase price was $25,000,002, matching the price at which Odyssey sold shares in its initial public offering.

What is the total number of Odyssey Therapeutics (ODTX) shares TPG funds beneficially own?

The reporting persons may be deemed to beneficially own 3,690,146 shares of Odyssey common stock. This includes shares held by TPG LSI Rise Orazio, L.P. and TPG LSI Rise Orazio II, L.P., over which the TPG control structure provides shared voting and dispositive power under SEC rules.

What agreements govern TPG’s investment in Odyssey Therapeutics (ODTX)?

Two key agreements are disclosed: a Share Purchase Agreement dated May 7, 2026 covering the $25,000,002 share purchase, and a Third Amended and Restated Investors' Rights Agreement dated June 16, 2025 providing registration rights for resale of the common stock issued at the IPO closing.

Does TPG indicate any specific plans to change control or strategy at Odyssey Therapeutics (ODTX)?

The filing states that, apart from the described investment, no specific plans or proposals are currently in place for actions such as mergers, board changes, or recapitalizations. However, the reporting persons reserve the right to review their position and consider such actions in the future.

When did the concurrent private placement in Odyssey Therapeutics (ODTX) close for TPG’s purchase?

The concurrent private placement closed on May 11, 2026, referred to as the “Closing.” On that date, Odyssey issued 1,388,889 shares of common stock to TPG LSI Rise Orazio II, L.P. in exchange for the aggregate purchase price of $25,000,002.