[SCHEDULE 13G/A] OnKure Therapeutics, Inc. Amended Passive Investment Disclosure
OnKure stake of 3.6% reported by Trails Edge
Trails Edge Capital Partners, Trails Edge Biotechnology Master Fund and Ortav Yehudai report their beneficial ownership of OnKure Therapeutics, Inc. Class A Common Stock as of June 30, 2026.
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Trails Edge Capital Partners, Trails Edge Biotechnology Master Fund and Ortav Yehudai report their beneficial ownership of OnKure Therapeutics, Inc. Class A Common Stock as of June 30, 2026. They collectively may be deemed to beneficially own 1,438,456 shares, representing 3.6% of the outstanding shares, all held directly by Trails Edge Biotechnology Master Fund. The percentage is based on 40,395,480 shares outstanding as of May 4, 2026. Each filer has sole voting and dispositive power over these shares and confirms ownership of 5 percent or less of the class.
Key Figures
Beneficially owned shares:1,438,456 sharesOwnership percentage:3.6%Shares outstanding baseline:40,395,480 shares+2 more
5 metrics
Beneficially owned shares1,438,456 sharesClass A Common Stock beneficially owned by the filers as of June 30, 2026
Ownership percentage3.6%Percent of OnKure Class A Common Stock beneficially owned by the filers
Shares outstanding baseline40,395,480 sharesOnKure Common Stock issued and outstanding as of May 4, 2026
Sole voting power1,438,456 sharesShares over which the filers report sole power to vote
Event DateJune 30, 2026Date as of which beneficial ownership is reported
Key Terms
beneficially own, Sole Voting Power, Sole Dispositive Power, Ownership of 5 percent or less of a class, +1 more
5 terms
beneficially ownfinancial
"each Filer may be deemed to beneficially own an aggregate of 1,438,456 shares"
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
Sole Voting Powerfinancial
"Sole Voting Power 1,438,456.00 6 | Shared Voting Power 0.00"
Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.
Sole Dispositive Powerfinancial
"Sole Dispositive Power 1,438,456.00 8 | Shared Dispositive Power 0.00"
Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.
Ownership of 5 percent or less of a classfinancial
"Item 5. | Ownership of 5 Percent or Less of a Class."
Schedule 13G/Aregulatory
"This report on /A (as amended, this "") is being filed"
A Schedule 13G/A is an amended public filing with the U.S. securities regulator that updates a previous Schedule 13G, disclosing when an individual or group holds a substantial (typically over 5%) stake in a company and is claiming a passive, non‑controlling intent. Investors monitor these updates because rising or falling holdings can signal changing confidence, potential future moves, or shifts in voting power — like watching a public ledger where large shareholders quietly adjust their positions.
FAQ
AI-generated questions and answers. How Rhea-AI works. Not financial advice.
What percentage of OnKure Therapeutics (OKUR) does Trails Edge beneficially own?
Trails Edge Capital Partners, Trails Edge Biotechnology Master Fund and Ortav Yehudai collectively may be deemed to beneficially own 3.6% of OnKure Therapeutics’ Class A Common Stock. This is based on 40,395,480 shares outstanding as of May 4, 2026.
How many OnKure Therapeutics (OKUR) shares are reported by Trails Edge?
The filers report beneficial ownership of 1,438,456 shares of OnKure Therapeutics Class A Common Stock. All 1,438,456 shares are held directly by Trails Edge Biotechnology Master Fund, with sole voting and dispositive power over these shares.
Who are the reporting persons in this Schedule 13G/A for OnKure Therapeutics (OKUR)?
The reporting persons are Trails Edge Capital Partners, LP, Trails Edge Biotechnology Master Fund, LP, and Ortav Yehudai. Trails Edge Capital is investment manager to the fund, and Mr. Yehudai is Chief Investment Officer of Trails Edge Capital and may be deemed a beneficial owner.
Does Trails Edge have sole or shared voting power over its OnKure Therapeutics (OKUR) shares?
The filing states sole voting power over 1,438,456 shares and no shared voting power. It also reports sole dispositive power over the same 1,438,456 shares, with no shared dispositive power reported by the filers.
What does the Schedule 13G/A say about owning 5 percent or less of OnKure Therapeutics (OKUR)?
The report specifies Ownership of 5 percent or less of a class for the filers. Their beneficial ownership of 3.6% of OnKure’s Class A Common Stock confirms that their holdings are below the 5% threshold for this security class.
What dates are important in this OnKure Therapeutics (OKUR) Schedule 13G/A filing?
The Event Date is June 30, 2026 for determining beneficial ownership. The ownership percentage is calculated using 40,395,480 shares outstanding as of May 4, 2026. The signatures from the filers are all dated August 14, 2026.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
OnKure Therapeutics, Inc.
(Name of Issuer)
Class A Common Stock, $0.0001 par value per share
(Title of Class of Securities)
68227Q105
(CUSIP Number)
06/30/2026
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
schemaVersion:
SCHEDULE 13G
CUSIP Number(s):
68227Q105
1
Names of Reporting Persons
Trails Edge Capital Partners, LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
1,438,456.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
1,438,456.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,438,456.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
3.6 %
12
Type of Reporting Person (See Instructions)
IA, PN
Comment for Type of Reporting Person: See Item 4 for additional information.
SCHEDULE 13G
CUSIP Number(s):
68227Q105
1
Names of Reporting Persons
Trails Edge Biotechnology Master Fund, LP
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
CAYMAN ISLANDS
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
1,438,456.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
1,438,456.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,438,456.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
3.6 %
12
Type of Reporting Person (See Instructions)
PN
Comment for Type of Reporting Person: See Item 4 for additional information.
SCHEDULE 13G
CUSIP Number(s):
68227Q105
1
Names of Reporting Persons
Ortav Yehudai
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
1,438,456.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
1,438,456.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,438,456.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
3.6 %
12
Type of Reporting Person (See Instructions)
IN
Comment for Type of Reporting Person: See Item 4 for additional information.
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
OnKure Therapeutics, Inc.
(b)
Address of issuer's principal executive offices:
6707 Winchester Circle, #400, Boulder, CO, 80301
Item 2.
(a)
Name of person filing:
This report on Schedule 13G/A (as amended, this "Schedule 13G") is being filed by Trails Edge Capital Partners, LP, a Delaware limited partnership ("Trails Edge Capital"), Trails Edge Biotechnology Master Fund, LP, a Cayman Islands limited partnership ("Trails Edge Biotechnology"), and Ortav Yehudai ("Mr. Yehudai"). Trails Edge Capital is the investment manager to Trails Edge Biotechnology, and Mr. Yehudai is the Chief Investment Officer of Trails Edge Capital. Each of Trails Edge Capital, Trails Edge Biotechnology and Mr. Yehudai are referred to individually as a "Filer" and collectively as the "Filers".
(b)
Address or principal business office or, if none, residence:
The address for each Filer is 3455 Peachtree Road NE, 5th Floor, Atlanta, GA 30326.
(c)
Citizenship:
See Item 4 of the cover page of each Filer.
(d)
Title of class of securities:
Class A Common Stock, $0.0001 par value per share
(e)
CUSIP No.:
68227Q105
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
As of June 30, 2026 (the "Event Date"), each Filer may be deemed to beneficially own an aggregate of 1,438,456 shares (the "Shares") of Class A Common Stock, $0.0001 par value per share (the "Common Stock"), of OnKure Therapeutics, Inc. (the "Issuer"). The 1,438,456 Shares reported as beneficially owned on this Schedule 13G by each Filer consist of 1,438,456 Shares held directly by Trails Edge Biotechnology. As a result, Trails Edge Biotechnology beneficially owns 3.6% of the outstanding Shares of the Issuer as of the Event Date. Trails Edge Capital, as the investment manager to Trails Edge Biotechnology, may be deemed to beneficially own these securities. Mr. Yehudai, as the Chief Investment Officer of Trails Edge Capital, exercises voting and investment discretion with respect to these securities and as such may be deemed to beneficially own 3.6% of the outstanding Shares of the Issuer as of the Event Date.
Ownership percentages are based on 40,395,480 shares of Common Stock issued and outstanding as of May 4, 2026, as reported by the Issuer in its Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on May 5, 2026.
(b)
Percent of class:
3.6 %
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
1,438,456.00
(ii) Shared power to vote or to direct the vote:
0.00
(iii) Sole power to dispose or to direct the disposition of:
1,438,456.00
(iv) Shared power to dispose or to direct the disposition of:
0.00
Item 5.
Ownership of 5 Percent or Less of a Class.
Ownership of 5 percent or less of a class
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
Not Applicable
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Trails Edge Capital Partners, LP
Signature:
/s/ Trails Edge Capital Partners, LLC, GP of Trails Edge Capital Partners, LP /s/ Ortav Yehudai
Name/Title:
Ortav Yehudai / Chief Investment Officer of Trails Edge Capital Partners, LLC
Date:
08/14/2026
Trails Edge Biotechnology Master Fund, LP
Signature:
/s/ Trails Edge GP, LLC, GP of Trails Edge Biotechnology Fund GP, LP, GP of Trails Edge Biotechnology Master Fund, LP /s/ Ortav Yehudai
Exhibit 1- Joint Filing Agreement, dated as of April 7, 2026, by and between Trails Edge Capital Partners, LP, Trails Edge Biotechnology Master Fund, LP and Ortav Yehudai (incorporated by reference to Exhibit 1 to the Schedule 13G filed with the Securities and Exchange Commission on April 7, 2026).
