StepStone reports 6.6% stake in OnKure (Class A)

OnKure Therapeutics ownership filing: StepStone entities report shared beneficial ownership of 2,660,612 shares of Class A Common Stock, representing 6.6% of the class.

Accepted by SEC EDGAR 04/07/2026 - 07:21 PM EDT Learn about SEC filing dates

Rhea-AI Filing Summary

OnKure Therapeutics ownership filing: StepStone entities report shared beneficial ownership of 2,660,612 shares of Class A Common Stock, representing 6.6% of the class. The filing cites 40,395,478 shares outstanding as of April 1, 2026. The report attributes shared voting and dispositive power to StepStone-related partnerships and managers.

Key Figures

Beneficial ownership: 2,660,612 shares Percent of class: 6.6% Shares outstanding: 40,395,478 shares +2 more

5 metrics

Beneficial ownership 2,660,612 shares shared ownership by StepStone entities

Percent of class 6.6% based on shares outstanding as of April 1, 2026

Shares outstanding 40,395,478 shares as of April 1, 2026 (issuer-provided)

CUSIP 68277Q105 OnKure Class A Common Stock identifier

Filing date / signature 04/07/2026 signature date for Schedule 13G

Key Terms

Schedule 13G, Beneficial ownership, Shared dispositive power, CUSIP

4 terms

Schedule 13G regulatory

"Name of the persons filing this report (the "Reporting Persons")"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

Beneficial ownership financial

"Amount beneficially owned: The information required by this item"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

Shared dispositive power regulatory

"Shared Dispositive Power 2,660,612.00"

CUSIP market

"Class A Common Stock, par value $0.0001 per share 68277Q105"

A CUSIP is a nine-character alphanumeric code that uniquely identifies a U.S. or Canadian financial security—such as a stock, bond, or fund share—like a Social Security number for an investment. It matters to investors because brokers, exchanges and record-keepers use the CUSIP to match trades, track ownership, settle transactions and pull accurate records, reducing errors and ensuring money and securities go to the right place.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake does StepStone report in OnKure (OKUR)?

StepStone reports shared beneficial ownership of 2,660,612 shares, equal to 6.6% of OnKure's Class A common stock, based on 40,395,478 shares outstanding as of April 1, 2026. The holding is reported across affiliated entities.

Which StepStone entities are named in the Schedule 13G for OKUR?

The filing lists StepStone Group LP, StepStone Master G, L.P., and StepStone VC MI-G GP, LLC. It explains the managerial and partnership relationships linking these reporting persons and their shared voting/dispositive arrangements.

What voting and dispositive powers are reported by StepStone?

StepStone reports 0 sole voting and dispositive power, and 2,660,612 shares of shared voting and shared dispositive power. The shares are therefore controlled jointly within the StepStone reporting group structure.

What share count did OnKure provide for ownership calculation?

OnKure provided a total of 40,395,478 shares outstanding as of April 1, 2026, which StepStone used to calculate its 6.6% ownership percentage reported on the Schedule 13G.

Who signed the Schedule 13G on behalf of StepStone?

The filing is signed by Jennifer Y. Ishiguro, Partner and Chief Legal Officer, acting for StepStone Group Holdings LLC and related StepStone entities, with signature dates shown as 04/07/2026.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

OnKure Therapeutics, Inc.

(Name of Issuer)

Class A Common Stock, par value $0.0001 per share

(Title of Class of Securities)

68277Q105

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 68277Q105

1

Names of Reporting Persons

StepStone Group LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,660,612.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,660,612.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,660,612.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.6 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 68277Q105

1

Names of Reporting Persons

StepStone Master G, L.P.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,660,612.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,660,612.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,660,612.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.6 %

12

Type of Reporting Person (See Instructions)

PN

SCHEDULE 13G

CUSIP Number(s): 68277Q105

1

Names of Reporting Persons

StepStone VC MI-G GP, LLC

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 2,660,612.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 2,660,612.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,660,612.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.6 %

12

Type of Reporting Person (See Instructions)

OO

SCHEDULE 13G

Item 1.
(a)	Name of issuer: OnKure Therapeutics, Inc.
(b)	Address of issuer's principal executive offices: 6707 Winchester Circle #400 Boulder, CO 80301
Item 2.
(a)	Name of person filing: The name of the persons filing this report (the "Reporting Persons") are: (i) StepStone Group LP ("StepStone"); (ii) StepStone Master G, L.P. ("Master G"); and (iii) StepStone VC MI-G GP, LLC ("MI-G GP"). MI-G GP is the general partner of Master G. StepStone is the sole managing member of MI-G GP. StepStone is the investment manager of each of Master G and MI-G GP. StepStone Group Holdings LLC ("StepStone Group Holdings") is the general partner of StepStone, and StepStone Group Inc. is the sole managing member of StepStone Group Holdings.
(b)	Address or principal business office or, if none, residence: The address of the principal business office of each of the Reporting Persons is: 4225 Executive Square, Suite 1600 La Jolla, CA 92037
(c)	Citizenship: Each of StepStone and Master G is a limited partnership organized under the laws of the State of Delaware. MI-G GP is a limited liability company organized under the laws of the State of Delaware.
(d)	Title of class of securities: Class A Common Stock, par value $0.0001 per share
(e)	CUSIP Number(s): 68277Q105
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover page to this Schedule 13G. The ownership percentages are based on 40,395,478 shares of Common Stock outstanding as of April 1, 2026, as provided by the Issuer.
(b)	Percent of class: See Item 4(a) above
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: See Item 4(a) above
	(ii) Shared power to vote or to direct the vote: See Item 4(a) above
	(iii) Sole power to dispose or to direct the disposition of: See Item 4(a) above
	(iv) Shared power to dispose or to direct the disposition of: See Item 4(a) above
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	Not Applicable
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

StepStone Group LP

Signature:	By: StepStone Group Holdings LLC, its general partner
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

Signature:	/s/ Jennifer Y. Ishiguro
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

StepStone Master G, L.P.

Signature:	By: StepStone Group LP, its investment manager
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

Signature:	By: Stepstone Group Holdings LLC, its general partner
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

Signature:	/s/ Jennifer Y. Ishiguro
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

StepStone VC MI-G GP, LLC

Signature:	By: StepStone Group LP, its investment manager
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

Signature:	By: Stepstone Group Holdings LLC, its general partner
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026

Signature:	/s/ Jennifer Y. Ishiguro
Name/Title:	Jennifer Y. Ishiguro Partner, Chief Legal Officer
Date:	04/07/2026