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BeOne Medicines director sells 31,028 depositary shares

The reported ADS sales were made under a Rule 10b5-1 plan adopted June 9, 2026, and the direct ordinary-share holding afterward was 4,588,113.

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Form Type
4

Rhea-AI Filing Summary

BeOne Medicines Ltd. director and Scientific Advisory Board Chair Xiaodong Wang reported exercising options covering 403,364 ordinary shares at an exercise price of $2.84 per share on October 27, 2026, and acquiring 31,028 American Depositary Shares (ADSs) at $36.90 per ADS. He sold 31,028 ADSs in 11 transactions that day; the reported weighted-average prices ranged from $355.5595 to $366.2205 per ADS. The sales were made under a Rule 10b5-1 trading plan adopted on June 9, 2026. The reported post-transaction position was 4,588,113 directly held ordinary shares, with zero shares remaining in the reported option position.

Insider Wang Xiaodong
Role Director
Sold 31,028 shs ($11.26M)
Approx. gross sale proceeds $11.26M
Approx. exercise cost $1.15M
Type Security Shares Price Value
Exercise Share Option (Right to Buy) F17, F18 403,364 $0.00 $0.00
Exercise American Depositary Shares F4 31,028 $36.90 $1.14M
Sale American Depositary Shares F4, F5, F6 880 $355.5595 $313K
Sale American Depositary Shares F4, F5, F7 1,440 $355.616 $512K
Sale American Depositary Shares F4, F5, F8 1,239 $357.5386 $443K
Sale American Depositary Shares F4, F5, F9 1,681 $358.7462 $603K
Sale American Depositary Shares F4, F5, F10 1,280 $359.7219 $460K
Sale American Depositary Shares F4, F5, F11 320 $360.6363 $115K
Sale American Depositary Shares F4, F5, F12 2,331 $362.3503 $845K
Sale American Depositary Shares F4, F5, F13 8,148 $363.242 $2.96M
Sale American Depositary Shares F4, F5, F14 2,841 $363.9492 $1.03M
Sale American Depositary Shares F4, F5, F15 3,965 $365.4293 $1.45M
Sale American Depositary Shares F4, F5, F16 6,903 $366.2205 $2.53M
Holding Ordinary Shares -- -- --
Holding Ordinary Shares F1 -- -- --
Holding Ordinary Shares F2 -- -- --
Holding Ordinary Shares F3 -- -- --
Holdings After Transaction: Share Option (Right to Buy) — 0 contracts (Direct); American Depositary Shares — 0 shares (Direct); Ordinary Shares — 4,588,113 shares (Direct); Ordinary Shares — 4,978,213 shares (Indirect, See Footnote)
Footnotes (18)
  1. F1. These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.
  2. F2. These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.
  3. F3. These securities are held by the spouse of the Reporting Person.
  4. F4. Each American Depositary Share represents 13 Ordinary Shares.
  5. F5. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.
  6. F6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  7. F7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.13 to $357.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  8. F8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.19 to $357.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  9. F9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.24 to $359.23, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  10. F10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.37 to $360.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  11. F11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.41 to $360.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  12. F12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.68 to $362.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  13. F13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.68 to $363.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  14. F14. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.68 to $364.51, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  15. F15. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $364.80 to $365.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  16. F16. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.88 to $366.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
  17. F17. The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
  18. F18. These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.
Ordinary shares underlying options exercised 403,364 ordinary shares Reported October 27, 2026
Option exercise price $2.84 per ordinary share Options reported October 27, 2026
ADSs acquired 31,028 ADSs Reported October 27, 2026
Reported acquisition price $36.90 per ADS ADS acquisition reported October 27, 2026
ADSs sold 31,028 ADSs Across 11 transactions on October 27, 2026
Reported weighted-average sale prices $355.5595–$366.2205 per ADS Sale transactions reported October 27, 2026
Direct ordinary shares following transactions 4,588,113 ordinary shares Reported after the October 27, 2026 transactions
Rule 10b5-1 trading plan regulatory
"The sale was effected pursuant to a Rule 10b5-1 trading plan"
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
weighted average price financial
"The price reported in Column 4 is a weighted average price"
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
American Depositary Share financial
"Each American Depositary Share represents 13 Ordinary Shares"
An American Depositary Share (ADS) is a U.S.-listed certificate that represents a specified number of shares in a foreign company, held by a custodian bank; it works like a receipt that allows U.S. investors to buy and trade foreign equity on American exchanges without dealing with another country’s markets. Investors care because ADSs make foreign stocks easier to access, improve liquidity and settlement in dollars, and can affect dividend payments, voting rights and regulatory oversight compared with buying the underlying foreign shares directly.
accelerated vesting technical
"subject to accelerated vesting upon certain termination events"
A contract feature that makes stock awards, options, or restricted shares become owned or exercisable earlier than the original schedule. It shortens or cancels the waiting period so recipients can sell, transfer, or exercise their equity sooner — think of a timed lock that is unlocked ahead of schedule. It matters to investors because it changes when shares enter the market, who controls them, and how much dilution or ownership concentration happens.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many ONC ADSs did Xiaodong Wang sell, and at what prices?

Xiaodong Wang sold 31,028 ADSs in 11 transactions on October 27, 2026, at reported weighted-average prices ranging from $355.5595 to $366.2205 per ADS. The sales were made under a Rule 10b5-1 trading plan adopted on June 9, 2026.

What vesting terms applied to the ONC options Xiaodong Wang exercised?

The options vested over four years: 25% on July 13, 2017, with the remainder in 36 successive equal monthly installments, subject to continued service. The footnote also states that unvested shares subject to the option were subject to accelerated vesting upon certain termination events.

How many ordinary shares does one ONC ADS represent?

Each ADS represents 13 Ordinary Shares.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Wang Xiaodong

(Last)(First)(Middle)
C/O BEONE MEDICINES I GMBH
AESCHENGRABEN 27, 21ST FLOOR

(Street)
BASEL4051

(City)(State)(Zip)

SWITZERLAND

(Country)
2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)XOther (specify below)
Chair, Scientific Advisory Brd
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
10/27/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Ordinary Shares4,588,113D
Ordinary Shares1,025,063ISee Footnote(1)
Ordinary Shares3,953,100ISee Footnote(2)
Ordinary Shares50ISee Footnote(3)
American Depositary Shares(4)10/27/2026M31,028A$36.931,028D
American Depositary Shares(4)10/27/2026S(5)880D$355.5595(6)30,148D
American Depositary Shares(4)10/27/2026S(5)1,440D$355.616(7)28,708D
American Depositary Shares(4)10/27/2026S(5)1,239D$357.5386(8)27,469D
American Depositary Shares(4)10/27/2026S(5)1,681D$358.7462(9)25,788D
American Depositary Shares(4)10/27/2026S(5)1,280D$359.7219(10)24,508D
American Depositary Shares(4)10/27/2026S(5)320D$360.6363(11)24,188D
American Depositary Shares(4)10/27/2026S(5)2,331D$362.3503(12)21,857D
American Depositary Shares(4)10/27/2026S(5)8,148D$363.242(13)13,709D
American Depositary Shares(4)10/27/2026S(5)2,841D$363.9492(14)10,868D
American Depositary Shares(4)10/27/2026S(5)3,965D$365.4293(15)6,903D
American Depositary Shares(4)10/27/2026S(5)6,903D$366.2205(16)0D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Share Option (Right to Buy)$2.84(17)10/27/2026M403,364 (18)11/15/2026Ordinary Shares403,364$00D
Explanation of Responses:
1. These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.
2. These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.
3. These securities are held by the spouse of the Reporting Person.
4. Each American Depositary Share represents 13 Ordinary Shares.
5. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.
6. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.04, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.13 to $357.09, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
8. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.19 to $357.95, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
9. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.24 to $359.23, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
10. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.37 to $360.33, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
11. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.41 to $360.97, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
12. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.68 to $362.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
13. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.68 to $363.67, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
14. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.68 to $364.51, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
15. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $364.80 to $365.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
16. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.88 to $366.45, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
17. The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.
18. These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.
Remarks:
/s/ Frank Collazo, as Attorney-in-Fact10/29/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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