BeOne Medicines executive sells ADS for tax withholding

BeOne Medicines Ltd. executive Wang Lai reported a small mandatory share sale tied to equity compensation.

Rhea-AI Filing Summary

BeOne Medicines Ltd. executive Wang Lai reported a small mandatory share sale tied to equity compensation. On the date shown, he sold 1,169 American Depositary Shares at a weighted average price of $265.3857 per ADS to satisfy tax withholding on a vesting restricted share unit award, rather than as a discretionary trade. Each ADS represents 13 ordinary shares. After these transactions, he continues to hold 1,694,888 ordinary shares directly, while additional ordinary shares are held indirectly through Wang Holdings LLC and an employee RMB share participation plan, for which he disclaims beneficial ownership except for any pecuniary interest.

Insider Trade Summary

Net Seller: 1,169 shares

Net Sell 4 txns

Insider Wang Lai

Role President, Global Head of R&D

Sold 1,169 shs ($310K)

Type	Security	Shares	Price	Value
Sale	American Depositary Shares	1,169	$265.3857	$310K
holding	Ordinary Shares	--	--	--
holding	Ordinary Shares	--	--	--
holding	RMB Shares	--	--	--

Holdings After Transaction: American Depositary Shares — 0 shares (Direct); Ordinary Shares — 1,694,888 shares (Direct); Ordinary Shares — 601,965 shares (Indirect, See Footnote); RMB Shares — 0 shares (Indirect, See Footnote)

Footnotes (7)

1. F1. These securities are held by Wang Holdings LLC, the limited liability company interests of which are owned by the Reporting Person, his spouse and a trust created by the Reporting Person for the benefit of his spouse and children, for which the Reporting Person disclaims beneficial ownership.
2. F2. The term "RMB Shares" is used herein to represent the ordinary shares, par value $0.0001 per share, of the Issuer, issued directly by the Issuer in the Issuer's initial public offering on the Science and Technology Innovation Board (the "STAR Market") of the Shanghai Stock Exchange (the "STAR Offering"), to permitted investors in Renminbi ("RMB") within the People's Republic of China ("PRC") in accordance with the rules of the STAR Market.
3. F3. The Issuer established an employee participation program ("RMB Shares Employee Participation Plan"), which allows certain executive officers and qualified employees of the Issuer's subsidiaries in the PRC to indirectly participate in the STAR Offering and purchase certain RMB Shares from the Issuer through an asset management plan administrated by China International Capital Corporation Limited in a transaction that is exempt under Rule 16b-3. The RMB Share Employee Participation Plan purchased an aggregate of 2,069,546 RMB Shares directly from the Issuer in the STAR Offering at the initial public offering price of RMB192.6 per RMB Share (or $30.1295 based on an assumed exchange rate of $1.00 = RMB6.3924).
4. F4. The Reporting Person, as an individual participant in the RMB Shares Employee Participation Plan, has contributed RMB10 million to the RMB Shares Employee Participation Plan. The Reporting Person may be deemed to have indirect economic interest in an indeterminable portion of the RMB Shares held by the RMB Shares Employee Participation Plan but does not have voting or dispositive power over any of such shares. The Reporting Person disclaims Section 16 beneficial ownership of the RMB Shares held by the RMB Shares Employee Participation Plan, except to the extent, if any, of his pecuniary interest therein. This report shall not be deemed an admission that the Reporting Person is the beneficial owner of such RMB Shares for Section 16 or any other purpose.
5. F5. Each American Depositary Share represents 13 Ordinary Shares.
6. F6. The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a restricted share unit award previously granted to the Reporting Person. 1/4th of the securities will vest on each anniversary of June 15, 2023, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.
7. F7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $265.385 to $265.775, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Key Figures

ADS sold: 1,169 ADS Weighted average sale price: $265.3857 per ADS Direct ordinary shares after transaction: 1,694,888 ordinary shares +5 more

8 metrics

ADS sold 1,169 ADS Open-market sale for tax withholding on RSU vesting

Weighted average sale price $265.3857 per ADS ADS sold in multiple trades between $265.385 and $265.775

Direct ordinary shares after transaction 1,694,888 ordinary shares Direct ownership following reported transactions

Indirect ordinary shares via Wang Holdings LLC 601,965 ordinary shares Held by Wang Holdings LLC; beneficial ownership disclaimed

RMB Shares in employee plan 2,069,546 RMB Shares Aggregate RMB Shares purchased in STAR Offering by employee plan

Executive contribution to RMB plan RMB10 million Amount contributed by Wang Lai to RMB Shares Employee Participation Plan

RMB Shares IPO price RMB192.6 per share (or $30.1295) Initial public offering price in STAR Offering

ADS to ordinary share ratio 1 ADS = 13 ordinary shares Conversion ratio for American Depositary Shares

Key Terms

RMB Shares, RMB Shares Employee Participation Plan, American Depositary Shares, restricted share unit award, +2 more

6 terms

RMB Shares financial

"The term "RMB Shares" is used herein to represent the ordinary shares..."

RMB Shares Employee Participation Plan financial

"The Issuer established an employee participation program ("RMB Shares Employee Participation Plan"), which allows certain executive officers..."

American Depositary Shares financial

"Each American Depositary Share represents 13 Ordinary Shares."

American depositary shares (ADSs) are a way for investors in the United States to buy shares of foreign companies without dealing with international markets directly. They represent ownership in a foreign company's stock and are traded on U.S. stock exchanges, making it easier for American investors to buy, sell, and own parts of companies from around the world.

restricted share unit award financial

"The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement..."

weighted average price financial

"The price reported in Column 4 is a weighted average price."

Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.

STAR Market financial

"the Issuer's initial public offering on the Science and Technology Innovation Board (the "STAR Market") of the Shanghai Stock Exchange..."

A Star Market is a specialized segment of a stock exchange designed to list fast-growing, technology- or innovation-focused companies under rules intended to make it easier for startups and research-driven firms to raise capital. For investors it matters because it provides a way to access potentially high-growth opportunities that come with higher risk and volatility—like buying early-stage products at a startup fair rather than established brands at a supermarket.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What did BeOne Medicines (ONC) executive Wang Lai disclose in this Form 4?

Wang Lai disclosed a small sale of 1,169 American Depositary Shares. The transaction was executed at a weighted average price of $265.3857 per ADS and was linked to tax withholding on a vesting restricted share unit award, not a discretionary open-market sale.

Was the BeOne Medicines (ONC) insider sale a discretionary trade?

The sale was not a discretionary trade. Footnotes state the 1,169 ADS were sold pursuant to a mandatory tax withholding provision in Wang Lai’s restricted share unit agreement, triggered by vesting, rather than an elective decision to reduce his investment position.

How many BeOne Medicines (ONC) shares does Wang Lai hold after the reported transactions?

After the transactions, Wang Lai directly holds 1,694,888 ordinary shares. He also has indirect interests in 601,965 ordinary shares via Wang Holdings LLC and in RMB Shares through an employee participation plan, though he disclaims beneficial ownership except for any pecuniary interest.

At what price were the BeOne Medicines (ONC) ADS sold in the reported transaction?

The reported weighted average sale price was $265.3857 per ADS. A footnote explains the 1,169 ADS were sold in multiple trades at prices ranging from $265.385 to $265.775, and detailed trade breakdowns are available upon request from the issuer or regulators.

What is the relationship between BeOne Medicines (ONC) ADS and ordinary shares?

Each American Depositary Share represents 13 ordinary shares of BeOne Medicines. This ratio is disclosed in a footnote, clarifying how ADS listed for trading correspond to the company’s underlying ordinary share capital when interpreting the reported insider transaction.

How does the RMB Shares Employee Participation Plan affect Wang Lai’s BeOne Medicines (ONC) holdings?

The RMB Shares Employee Participation Plan holds 2,069,546 RMB Shares total. Wang Lai contributed RMB10 million and may have an indirect economic interest in a portion of these, but he has no voting or dispositive power and disclaims Section 16 beneficial ownership, except for any pecuniary interest.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 06/18/2026 - 05:19 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Wang Lai

(Last) (First) (Middle)

C/O BEONE MEDICINES I GMBH

AESCHENGRABEN 27, 21ST FLOOR

(Street)

BASEL 4051

(City) (State) (Zip)

SWITZERLAND

(Country)

2. Issuer Name and Ticker or Trading Symbol
BeOne Medicines Ltd. [ ONC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President, Global Head of R&D

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
06/16/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares								1,694,888	D
Ordinary Shares								601,965	I	See Footnote(1)
RMB Shares(2)								0(3)(4)	I	See Footnote(4)
American Depositary Shares(5)	06/16/2026		S(6)		1,169	D	$265.3857(7)	0	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. These securities are held by Wang Holdings LLC, the limited liability company interests of which are owned by the Reporting Person, his spouse and a trust created by the Reporting Person for the benefit of his spouse and children, for which the Reporting Person disclaims beneficial ownership.

2. The term "RMB Shares" is used herein to represent the ordinary shares, par value $0.0001 per share, of the Issuer, issued directly by the Issuer in the Issuer's initial public offering on the Science and Technology Innovation Board (the "STAR Market") of the Shanghai Stock Exchange (the "STAR Offering"), to permitted investors in Renminbi ("RMB") within the People's Republic of China ("PRC") in accordance with the rules of the STAR Market.

3. The Issuer established an employee participation program ("RMB Shares Employee Participation Plan"), which allows certain executive officers and qualified employees of the Issuer's subsidiaries in the PRC to indirectly participate in the STAR Offering and purchase certain RMB Shares from the Issuer through an asset management plan administrated by China International Capital Corporation Limited in a transaction that is exempt under Rule 16b-3. The RMB Share Employee Participation Plan purchased an aggregate of 2,069,546 RMB Shares directly from the Issuer in the STAR Offering at the initial public offering price of RMB192.6 per RMB Share (or $30.1295 based on an assumed exchange rate of $1.00 = RMB6.3924).

4. The Reporting Person, as an individual participant in the RMB Shares Employee Participation Plan, has contributed RMB10 million to the RMB Shares Employee Participation Plan. The Reporting Person may be deemed to have indirect economic interest in an indeterminable portion of the RMB Shares held by the RMB Shares Employee Participation Plan but does not have voting or dispositive power over any of such shares. The Reporting Person disclaims Section 16 beneficial ownership of the RMB Shares held by the RMB Shares Employee Participation Plan, except to the extent, if any, of his pecuniary interest therein. This report shall not be deemed an admission that the Reporting Person is the beneficial owner of such RMB Shares for Section 16 or any other purpose.

5. Each American Depositary Share represents 13 Ordinary Shares.

6. The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a restricted share unit award previously granted to the Reporting Person. 1/4th of the securities will vest on each anniversary of June 15, 2023, subject to continued service. Unvested securities are subject to accelerated vesting upon certain termination events.

7. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $265.385 to $265.775, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Remarks:

	/s/ Qing Nian, as Attorney-in-Fact	06/18/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)