OPKO Health (OPK) VP withholds 53,266 shares for taxes

Rhea-AI Filing Summary

OPKO HEALTH, INC. executive VP-Administration and director Steven D. Rubin reported a tax-related share withholding. On 2026-07-24, 53,266 shares of common stock were withheld at $1.22 per share to satisfy tax obligations on vested restricted stock units, leaving 6,571,966 shares directly owned.

Insider Trade Summary

Net Seller: 53,266 shares

Net Sell 1 txn

Insider Rubin Steven D

Role Executive VP-Administration

Type	Security	Shares	Price	Value
Tax Withholding	Common Stock F1	53,266	$1.22	$65K

Holdings After Transaction: Common Stock — 6,571,966 shares (Direct)

Footnotes (1)

1. F1. This number represents shares of common stock par value $0.01 per shares of OPKO Health, Inc. withheld to satisfy the tax withholding obligation due upon vesting of restricted stock units.

Key Figures

Shares withheld for taxes: 53,266 shares Per-share value for withholding: $1.22 per share Shares owned after transaction: 6,571,966 shares

3 metrics

Shares withheld for taxes 53,266 shares Common stock withheld on 2026-07-24 to satisfy tax obligations on RSU vesting

Per-share value for withholding $1.22 per share Value assigned to the 53,266 withheld shares in the tax-withholding disposition

Shares owned after transaction 6,571,966 shares Direct OPKO Health common stock holdings of Steven D. Rubin following the withholding

Key Terms

restricted stock units, tax withholding obligation, tax-withholding disposition

3 terms

restricted stock units financial

"due upon vesting of restricted stock units"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

tax withholding obligation financial

"withheld to satisfy the tax withholding obligation due upon vesting"

tax-withholding disposition financial

"transaction_action: tax-withholding disposition"

A tax-withholding disposition is an event or transaction—such as selling or transferring securities, exercising options, or receiving compensation—that triggers a requirement to hold back part of the payment and remit it to tax authorities. It matters to investors because it reduces the cash they receive immediately and can change the timing and amount of taxable income, like a cashier taking a portion of your sale proceeds to pay taxes before you get the rest.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Form 4 Insider Transactions: What Each Field Means →

Available on EDGAR 07/28/2026 - 04:21 PM Accepted by SEC EDGAR 07/28/2026 - 04:21 PM Learn about SEC filing dates

FAQ

What did OPKO Health (OPK) executive Steven D. Rubin report on this Form 4?

Steven D. Rubin reported that 53,266 OPKO Health common shares were withheld at $1.22 per share to cover tax obligations arising from vested restricted stock units, leaving him with 6,571,966 shares of directly owned common stock after the transaction.

Was the OPKO (OPK) Form 4 transaction an open-market sale of shares?

No. The Form 4 states that 53,266 shares were withheld to satisfy tax withholding obligations upon vesting of restricted stock units, meaning the shares were delivered for tax purposes rather than sold in an open-market transaction to third-party buyers.

How many OPKO (OPK) shares does Steven D. Rubin own after this Form 4 event?

After the tax-withholding disposition, Steven D. Rubin directly owns 6,571,966 shares of OPKO Health common stock. This figure reflects his direct holdings immediately following the withholding of 53,266 shares for tax obligations tied to restricted stock unit vesting.

What price per share was used in Steven D. Rubin's OPKO (OPK) tax-withholding transaction?

The Form 4 reports a value of $1.22 per share for the 53,266 OPKO Health shares withheld. This price is used to determine the value of shares delivered to meet Rubin’s tax withholding obligation from the vesting of restricted stock units.

What triggered the share withholding reported in OPKO (OPK) executive Rubin’s Form 4?

The withholding arose from the vesting of restricted stock units. According to the footnote, OPKO Health withheld 53,266 shares of common stock to satisfy Steven D. Rubin’s tax withholding obligation due upon that vesting event, rather than conducting a market sale.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Rubin Steven D

(Last) (First) (Middle)

OPKO HEALTH, INC.

4400 BISCAYNE BLVD.

(Street)

MIAMI FLORIDA 33137

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
OPKO HEALTH, INC. [ OPK ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Executive VP-Administration

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
07/24/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/24/2026		F		53,266(1)	D	$1.22	6,571,966	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. This number represents shares of common stock par value $0.01 per shares of OPKO Health, Inc. withheld to satisfy the tax withholding obligation due upon vesting of restricted stock units.

	Steven D. Rubin	07/28/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)