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Puma Biotechnology Inc SEC Filings

PBYI NASDAQ

Welcome to our dedicated page for Puma Biotechnology SEC filings (Ticker: PBYI), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

NERLYNX sales trends, clinical-trial milestones, and royalty obligations are scattered across hundreds of pages of Puma Biotechnology’s SEC reports. Finding exactly where the company discloses HER2-positive breast-cancer data—or when an executive exercises options—can feel impossible.

That’s why Stock Titan pairs every Puma Biotechnology quarterly earnings report 10-Q filing with an AI-powered summary that extracts NERLYNX revenue, R&D spend, and cash-runway details in seconds. Need to decode an 8-K about a Phase III update? Our engine tags the material event and explains what it means for upcoming FDA reviews—think Puma Biotechnology 8-K material events explained. Looking for real-time alerts on Puma Biotechnology Form 4 insider transactions? We post them the moment they hit EDGAR, then highlight trends like cumulative buys before clinical catalysts.

All core submissions are covered: the Puma Biotechnology annual report 10-K simplified to spotlight license milestones and patent cliffs; the proxy statement detailing executive compensation; and each Form 4 showing Puma Biotechnology executive stock transactions Form 4. You can even search “understanding Puma Biotechnology SEC documents with AI” or “Puma Biotechnology SEC filings explained simply” and land here to compare segments, track dilution, or monitor cash burn. Whether you’re verifying a Puma Biotechnology insider trading Form 4 transactions entry or running a Puma Biotechnology earnings report filing analysis, our platform delivers answers—without the biotech jargon.

Rhea-AI Summary

Puma Biotechnology, Inc. (Nasdaq: PBYI) filed a Form 8-K announcing that its Board of Directors approved and adopted Fifth Amended and Restated Bylaws on June 19, 2025. The revisions align the company’s corporate governance documents with recent updates to Delaware corporate law and include conforming and ministerial edits. No changes to the company’s fiscal year, capital structure, or financial guidance were disclosed. The amended bylaws are filed as Exhibit 3.1 and incorporated by reference.

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FAQ

What is the current stock price of Puma Biotechnology (PBYI)?

The current stock price of Puma Biotechnology (PBYI) is $3.33 as of June 28, 2025.

What is the market cap of Puma Biotechnology (PBYI)?

The market cap of Puma Biotechnology (PBYI) is approximately 166.3M.

What is the core focus of Puma Biotechnology Inc?

Puma Biotechnology Inc specializes in the development and commercialization of innovative cancer therapies, primarily through its in-licensing model for drug candidates in the oncology space.

How does Puma Biotechnology generate revenue?

The company generates revenue by in-licensing promising drug candidates that have undergone initial clinical testing and then advancing these therapies to commercialization, particularly in targeted oncology treatments.

What is NERLYNX and what does it treat?

NERLYNX is an oral formulation of neratinib commercialized by Puma Biotechnology Inc, and it is used in the treatment of HER2-positive breast cancer.

Can you explain the mechanism of alisertib?

Alisertib is a selective small-molecule inhibitor of aurora kinase A that disrupts mitosis in rapidly proliferating tumor cells, ultimately inducing apoptosis and reducing tumor growth.

What is the significance of Puma Biotechnology's in-licensing strategy?

The in-licensing strategy allows Puma Biotechnology to acquire already validated drug candidates, reducing early development risks and expediting the pathway to market for their innovative cancer therapies.

How does Puma Biotechnology maintain its competitive advantage?

The company differentiates itself through its focused portfolio of targeted cancer therapies, rigorous clinical development processes, and a strategic approach to in-licensing that prioritizes compounds with proven clinical potential.

What role does clinical development play in Puma Biotechnology's operations?

Clinical development is integral to Puma Biotechnology's operations, ensuring that each candidate undergoes thorough evaluation to validate safety and efficacy, which reinforces the company’s expertise and credibility.

How does Puma Biotechnology contribute to advancements in cancer care?

Through its development of targeted therapeutics like NERLYNX and alisertib, Puma Biotechnology actively addresses unmet needs in cancer treatment by leveraging scientific insights and rigorous clinical research.
Puma Biotechnology Inc

NASDAQ:PBYI

PBYI Rankings

PBYI Stock Data

166.29M
41.85M
15.35%
59.27%
6.36%
Biotechnology
Pharmaceutical Preparations
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United States
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