[Form 4] PRECIGEN, INC. Insider Trading Activity

Rhea-AI Filing Summary

Precigen, Inc. (PGEN)Randal J. Kirk on a Form 4. Through entity Kapital Joe, he sold 1,086,153 shares of common stock on 11/19/2025 at a weighted average price of $4.47, 942,832 shares on 11/20/2025 at a weighted average price of $4.08, and 937,308 shares on 11/21/2025 at $3.83.

The filing notes that the first two prices are weighted averages for multiple trades within reported price ranges, and Kirk undertakes to provide full trade details on request. After these sales, he continues to report large indirect beneficial ownership positions in Precigen through multiple entities, including 7,434,384 shares held by Kapital Joe and 82,164,767 shares held by R.J. Kirk Declaration of Trust, along with additional holdings through various family and investment vehicles.

Insights

Equity Ownership and Governance Analyst

Large insider sales by a 10% owner/director reduce direct exposure but leave substantial indirect holdings outstanding.

The filing shows that **Randal J. Kirk**, a **director** and **10% owner** of **Precigen, Inc. (PGEN)**, reported three open‑market sales of common stock on 11/19/2025, 11/20/2025, and 11/21/2025. Through **Kapital Joe, LLC**, he sold 1,086,153 shares at a weighted average of $4.47, 942,832 shares at a weighted average of $4.08, and 937,308 shares at a weighted average of $3.83. After these sales, Kapital Joe still held 5,554,244 shares indirectly for his benefit.

Beyond Kapital Joe, the filing lists large additional indirect holdings in multiple entities, including **82,164,767** shares via **R.J. Kirk DOT** and multi‑million share positions in several other LLCs and partnerships, plus 6,085,471 shares via **Third Security, LLC** and 1,144,481 shares held by his spouse. All of these may be deemed beneficially owned under Rule 13d‑3, although he disclaims beneficial ownership except to the extent of any pecuniary interest. This means his economic exposure remains very significant even after the reported sales.

The concrete takeaway is a noticeable reduction in one indirect position, not an exit: a total of 2,966,293 shares were sold over three days, while aggregate indirect positions across entities remain large. The sales were executed over price ranges disclosed in the footnotes, and the weighted‑average disclosure suggests many small trades within those bands. A key item to watch over the next few quarters is whether similar Form 4 filings show continued net selling from these entities or a stable remaining stake.

11/21/2025 - 07:54 PM

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

KIRK RANDAL J

(Last) (First) (Middle)

C/O THIRD SECURITY, LLC

1881 GROVE AVENUE

(Street)

RADFORD VA 24141

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
PRECIGEN, INC. [ PGEN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
11/19/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/19/2025		S		1,086,153	D	$4.47(1)	7,434,384	I	by Kapital Joe(3)
Common Stock	11/20/2025		S		942,832	D	$4.08(2)	6,491,552	I	by Kapital Joe(3)
Common Stock	11/21/2025		S		937,308	D	$3.83	5,554,244	I	by Kapital Joe(3)
Common Stock								82,164,767	I	by. R.J. Kirk DOT(3)
Common Stock								1,096,686	I	by Parkview 2020(3)
Common Stock								490,401	I	by JPK 2008(3)
Common Stock								3,703,398	I	by JPK 2009(3)
Common Stock								1,654,363	I	by JPK 2012(3)
Common Stock								489,438	I	by MGK 2008(3)
Common Stock								3,944,437	I	by MGK 2009(3)
Common Stock								1,637,040	I	by MGK 2011(3)
Common Stock								578,079	I	by ZSK 2008(3)
Common Stock								351,120	I	by ZSK 2009(3)
Common Stock								453,731	I	by Kellie L. Banks LTT(3)
Common Stock								1,403	I	by Lotus(3)
Common Stock								14,597,161	I	by Sunset 2020(3)
Common Stock								6,085,471	I	by Third Security(3)
Common Stock								1,144,481	I	by Spouse

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.31 to $4.68, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4.

2. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.90 to $4.42, inclusive. The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) to this Form 4.

3. Randal J. Kirk controls each of Kapital Joe, LLC ("Kapital Joe"), R.J. Kirk Declaration of Trust ("R.J. Kirk DOT"), Parkview 2020 Limited Partnership ("Parkview 2020"), JPK 2008 LLC ("JPK 2008"), JPK 2009 LLC ("JPK 2009"), JPK 2012 LLC ("JPK 2012"), MGK 2008 LLC ("MGK 2008"), MGK 2009 LLC ("MGK 2009"), MGK 2011 LLC ("MGK 2011"), ZSK 2008 LLC ("ZSK 2008"), ZSK 2009 LLC ("ZSK 2009"), Kellie L. Banks (2009) Long Term Trust ("Kellie L. Banks LTT"), Lotus Capital (2000) Company, Inc. ("Lotus"), Sunset 2020 LLC ("Sunset 2020") and Third Security, LLC ("Third Security"). Shares held by these entities may be deemed to be beneficially owned (as defined under Rule 13d-3 promulgated under the Securities Exchange Act of 1934, as amended) by Mr. Kirk. Mr. Kirk disclaims beneficial ownership of such shares, except to the extent of any pecuniary interest therein.

Remarks:

	/s/ Randal J. Kirk	11/21/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did PGEN report for Randal J. Kirk?

The Form 4 shows that Randal J. Kirk, a director and 10% owner of Precigen, Inc. (PGEN), reported sales of common stock on 11/19/2025, 11/20/2025, and 11/21/2025 through the entity Kapital Joe.

How many PGEN shares did Kapital Joe sell on 11/19/2025 and at what price?

On 11/19/2025, Kapital Joe sold 1,086,153 shares of PGEN common stock at a weighted average price of $4.47 per share, with individual trade prices ranging from $4.31 to $4.68.

What were the PGEN share sales on 11/20/2025 and 11/21/2025?

On 11/20/2025, Kapital Joe sold 942,832 shares at a weighted average price of $4.08, with trades between $3.90 and $4.42. On 11/21/2025, it sold 937,308 shares at $3.83 per share.

How many PGEN shares does Randal J. Kirk report owning after these transactions?

Following the reported sales, Randal J. Kirk reports indirect beneficial ownership of 7,434,384 shares through Kapital Joe and additional indirect holdings, including 82,164,767 shares through R.J. Kirk Declaration of Trust and other entities and family vehicles listed in the Form 4.

Through which entities does Randal J. Kirk hold indirect PGEN shares?

The filing states that Kirk controls entities including Kapital Joe, R.J. Kirk Declaration of Trust, Parkview 2020, several JPK, MGK, and ZSK LLCs, Kellie L. Banks LTT, Lotus, Sunset 2020, and Third Security, and that shares held by these entities may be deemed beneficially owned by him.

Does Randal J. Kirk claim full beneficial ownership of all indirectly held PGEN shares?

The Form 4 notes that shares held by the listed entities may be deemed beneficially owned by Randal J. Kirk under Rule 13d-3, but he disclaims beneficial ownership of such shares except to the extent of any pecuniary interest.