PHIO insider Form 4 shows CEO purchase and 276,421 shares owned

Rhea-AI Filing Summary

Phio Pharmaceuticals Corp. (PHIO) reported an insider purchase by its Chairman, President and CEO. On 11/18/2025, the executive, who also serves as a director, bought 5,000 shares of Phio common stock at a price of $1.27 per share in an open-market transaction coded "P" for purchase.

After this transaction, the reporting person beneficially owned 276,421 shares of common stock, which includes shares underlying unvested restricted stock units. All reported holdings are listed as directly owned.

Insider Trade Summary

Net Buyer: 5,000 shares ($6,350)

Net Buy 1 txn

Insider Bitterman Robert J

Role Chairman, Pres. & CEO

Bought 5,000 shs ($6K)

Type	Security	Shares	Price	Value
Purchase	Common Stock, $.0001 par value	5,000	$1.27	$6K

Holdings After Transaction: Common Stock, $.0001 par value — 276,421 shares (Direct)

Footnotes (1)

1. [object Object]

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Bitterman Robert J

(Last) (First) (Middle)

C/O PHIO PHARMACEUTICALS CORP.

411 SWEDELAND RD., STE 23-1080

(Street)

KING OF PRUSSIA PA 19406

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Phio Pharmaceuticals Corp. [ PHIO ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chairman, Pres. & CEO

3. Date of Earliest Transaction (Month/Day/Year)
11/18/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, $.0001 par value	11/18/2025		P		5,000	A	$1.27	276,421(1)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Includes shares of common stock underlying unvested restricted stock units.

	/s/ Lisa C. Carson, Attorney-in-fact	11/19/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did PHIO report in this Form 4?

The filing reports that Phio Pharmaceuticals Corp.'s Chairman, President and CEO, who is also a director, purchased 5,000 shares of common stock on 11/18/2025.

At what price were the PHIO shares purchased by the CEO?

The CEO purchased 5,000 shares of Phio Pharmaceuticals Corp. common stock at a price of $1.27 per share.

How many PHIO shares does the reporting person own after this transaction?

Following the reported transaction, the reporting person beneficially owned 276,421 shares of Phio Pharmaceuticals Corp. common stock, including shares underlying unvested restricted stock units.

What is the relationship of the reporting person to Phio Pharmaceuticals Corp. (PHIO)?

The reporting person is a director and serves as Chairman, President and Chief Executive Officer of Phio Pharmaceuticals Corp.

Was this PHIO Form 4 filed for one or multiple reporting persons?

The Form 4 was filed by one reporting person, as indicated by the checked box for "Form filed by One Reporting Person."

What type of security did the PHIO insider purchase?

The insider purchased common stock of Phio Pharmaceuticals Corp. with a par value of $0.0001 per share.