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Biotech leader Ann Cunningham joins Alterity Therapeutics (NASDAQ: ATHE) board

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6-K

Rhea-AI Filing Summary

Alterity Therapeutics Limited has appointed Ms Ann Cunningham as an independent Non-Executive Director to its Board, effective 17 April 2026. She brings more than 25 years of global pharmaceutical and biotechnology experience, with deep expertise in commercial strategy across neurodegenerative disease and psychiatry.

Cunningham has held senior roles at Eli Lilly and Teva Pharmaceuticals, leading marketing and sales teams and overseeing neurodegenerative and psychiatry portfolios. Her appointment comes as Alterity prepares to advance its lead asset ATH434 into Phase 3 development for Multiple System Atrophy and move toward potential commercialisation.

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Appointment effective date 17 April 2026 Effective date of Ann Cunningham’s appointment as Non-Executive Director
Industry experience More than 25 years Cunningham’s global pharmaceutical and biotechnology experience
Development stage Phase 3 Planned pivotal trial stage for ATH434 in Multiple System Atrophy
Multiple System Atrophy medical
"late-stage development in Multiple System Atrophy (MSA)"
A progressive neurological disorder that damages multiple areas of the nervous system, causing problems with movement, balance and involuntary functions like blood pressure and bladder control; think of it as critical wiring in the body slowly failing. Investors care because the condition defines the size and urgency of the market for treatments, influences clinical trial difficulty and regulatory risk, and can lead to high per-patient pricing but also greater development uncertainty.
Phase 3 pivotal trial medical
"Alterity is preparing to initiate a Phase 3 pivotal trial in MSA"
A phase 3 pivotal trial is the large, final clinical study that tests whether a new drug or medical treatment works and is safe enough for regulators to approve it for widespread use. Think of it as the full-scale dress rehearsal before a product launches: positive results can unlock regulatory approval and big commercial upside, while failures can halt a program and significantly affect investor value.
Non-Executive Director financial
"appointment of Ms Ann Cunningham to its Board of Directors as an independent Non-Executive Director"
A non-executive director is a member of a company’s board who does not work for the company day-to-day but provides independent oversight, strategic guidance and checks on management. For investors, they matter because they act like an impartial referee or outside advisor, helping ensure decisions protect shareholder interests, reduce risks of poor governance, and add credibility to financial reporting and long-term strategy.
forward-looking statements regulatory
"This press release contains "forward-looking statements" within the meaning of section 27A"
Forward-looking statements are predictions or plans that companies share about what they expect to happen in the future, like estimating sales or profits. They matter because they help investors understand a company's outlook, but since they are based on guesses and assumptions, they can sometimes be wrong.
development stage enterprise financial
"ALTERITY THERAPEUTICS LIMITED (a development stage enterprise)"

 

 

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 6-K

 

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-163

UNDER THE SECURITIES EXCHANGE ACT OF 1934

 

For the month of April 2026

 

Alterity Therapeutics Limited

(Name of Registrant)

 

Level 14, 350 Collins Street, Melbourne, Victoria 3000 Australia

(Address of Principal Executive Office)

 

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

 

Form 20-F ☒       Form 40-F ☐

 

This Form 6-K is being incorporated by reference into our Registration Statement on Form S-8 (Files No. 333-251073, 333-248980 and 333-228671) and our Registration Statements on Form F-3 (Files No. 333-274816, 333-251647, 333-231417 and 333-250076)

 

 

 

 

ALTERITY THERAPEUTICS LIMITED

(a development stage enterprise)

 

The following exhibits are submitted:

 

99.1

Alterity Appoints Biotech Executive Ann Cunningham to Board

 

1

 

SIGNATURE

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

 

 

Alterity Therapeutics Limited

     
 

By:

/s/ Julian Babarczy

   

Julian Babarczy

   

Chairman

 

Date: April 17, 2026

2

Exhibit 99.1

 

ex_936910img001.jpg

 

 

Alterity Therapeutics Appoints Highly Experienced Biotech Executive Ann Cunningham to its Board of Directors

 

MELBOURNE, AUSTRALIA AND SAN FRANCISCO, USA  17 April 2026: Alterity Therapeutics Limited (ASX: ATH, NASDAQ: ATHE) (“Alterity” or “the Company”), a biotechnology company dedicated to developing disease modifying treatments for neurodegenerative diseases, today announced the appointment of Ms Ann Cunningham to its Board of Directors as an independent Non-Executive Director, effective 17th April 2026. Ms Cunningham’s appointment further strengthens Alterity’s Board composition, adding significant global commercial and strategic expertise as the Company transitions toward late-stage development in Multiple System Atrophy (MSA).

 

Ms Cunningham brings more than 25 years of global pharmaceutical and biotechnology experience, with deep expertise in commercial strategy and leadership across neurodegenerative disease and psychiatry. She has held senior roles at leading global organisations including Eli Lilly and Company and Teva Pharmaceuticals, where she led multiple marketing and sales teams and was responsible for neurodegenerative and psychiatry portfolios.

 

"We are delighted to welcome Ann to the Alterity Board at a pivotal stage in the Company’s evolution as we prepare to advance ATH434 into Phase 3 development,” said Julian Babarczy, Alterity’s Non-Executive Chairman of the Board of Directors. “Ann brings an outstanding combination of global pharmaceutical experience, commercial leadership and deep domain expertise in neurodegenerative diseases. Her experience in shaping commercial strategy for innovative therapies will be highly valuable as we position ATH434 for late-stage development and, ultimately, commercialisation. Importantly, Ann’s perspective will strengthen the Board as we focus on executing our Phase 3 program and maximising the value of our pipeline for shareholders."

 

Ms Cunningham commented, "I am excited to join Alterity at such a pivotal time, with promising clinical data driving strong momentum for ATH434 as a potential disease modifying treatment for patients suffering from neurodegenerative diseases. In MSA, the Company is addressing a significant unmet need, and I look forward to adding my patient-focused experience alongside the Board and management team to support the next phase of growth."

 

Ann Cunningham is the Founder and Chief Executive Officer of i³ Strategy Partners, a pharmaceutical consulting group focused on improving health outcomes through innovative patient engagement strategies, particularly within underserved communities. Ms. Cunningham has guided senior pharmaceutical and biotechnology executives in planning and executing multiple successful portfolio strategies and blockbuster brand launches, including instrumental roles in the successful commercial launch and sales of Lilly’s Cymbalta®, for which she led the development and execution of the “Depression Hurts” consumer campaign, and Otsuka America’s Rexulti®, serving as Senior Director, Global Brand Lead. While at Lilly, she also led psychiatry sales teams as Area Sales Director responsible for Cymbalta®, Zyprexa® and Strattera®. Ms. Cunningham also led the commercial development of a product portfolio as Vice President of Neurodegenerative Disease and Psychiatry at Teva Pharmaceutical Industries. She currently serves on the Board of Directors of Vistagen Therapeutics and previously served as its Chief Commercial Officer. Ms. Cunningham holds a B.A. in Psychology from Yale University and an MBA from the University of Michigan, Stephen M. Ross School of Business.

 

About Alterity Therapeutics Limited

 

Alterity Therapeutics is a clinical stage biotechnology company dedicated to creating an alternate future for people living with neurodegenerative diseases. The Company is focused on developing disease modifying therapies in Multiple System Atrophy (MSA) and related Parkinsonian disorders. Alterity is preparing to initiate a Phase 3 pivotal trial in MSA, a rare and rapidly progressive disease. ATH434, the Company’s lead asset, has demonstrated clinically meaningful efficacy in a randomized, double-blind, placebo-controlled Phase 2 clinical trial in participants with MSA. Alterity has further reported positive data in its open label Phase 2 clinical trial in participants with advanced MSA. In addition, Alterity has a broad drug discovery platform generating patentable chemical compounds to treat the underlying pathology of neurological diseases. The Company is based in Melbourne, Australia, and San Francisco, California, USA. For further information please visit the Company’s website at https://alteritytx.com.

 

Authorisation & Additional information

This announcement was authorized by the Board of Alterity Therapeutics Limited.

 

Contacts:

 

Investors:

Elyse Shapiro

ir@alteritytx.com

 

Remy Bernarda

Investor Relations Advisory Solutions

ir@alteritytx.com

+1 (415) 203-6386

 

 

 

Media

 

Casey McDonald

Tiberend Strategic Advisors, Inc.

cmcdonald@tiberend.com

+1 (646) 577-8520

 

Forward Looking Statements

 

This press release contains "forward-looking statements" within the meaning of section 27A of the Securities Act of 1933 and section 21E of the Securities Exchange Act of 1934. The Company has tried to identify such forward-looking statements by use of such words as "expects," "intends," "hopes," "anticipates," "believes," "could," "may," "evidences" and "estimates," and other similar expressions, but these words are not the exclusive means of identifying such statements.

 

Important factors that could cause actual results to differ materially from those indicated by such forward-looking statements are described in the sections titled Risk Factors in the Companys filings with the SEC, including its most recent Annual Report on Form 20-F as well as reports on Form 6-K, including, but not limited to the following: statements relating to the Company's drug development program, including, but not limited to the initiation, progress and outcomes of clinical trials of the Company's drug development program, including, but not limited to, ATH434, and any other statements that are not historical facts. Such statements involve risks and uncertainties, including, but not limited to, those risks and uncertainties relating to the difficulties or delays in financing, development, testing, regulatory approval, production and marketing of the Companys drug components, including, but not limited to, ATH434, the ability of the Company to procure additional future sources of financing, unexpected adverse side effects or inadequate therapeutic efficacy of the Company's drug compounds, including, but not limited to, ATH434, that could slow or prevent products coming to market, the uncertainty of obtaining patent protection for the Company's intellectual property or trade secrets, the uncertainty of successfully enforcing the Companys patent rights and the uncertainty of the Company freedom to operate.

 

Any forward-looking statement made by us in this press release is based only on information currently available to us and speaks only as of the date on which it is made. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.

 

 

 

FAQ

What did Alterity Therapeutics (ATHE) announce in this Form 6-K?

Alterity Therapeutics announced the appointment of Ann Cunningham as an independent Non-Executive Director, effective 17 April 2026. The company highlights her extensive commercial and neurodegenerative disease experience as it prepares ATH434 for Phase 3 development in Multiple System Atrophy and potential commercialisation.

Who is Ann Cunningham and what experience does she bring to Alterity Therapeutics (ATHE)?

Ann Cunningham is a biotech and pharmaceutical executive with more than 25 years of global experience. She has led commercial strategy and sales in neurodegenerative disease and psychiatry at companies including Eli Lilly and Teva, and currently serves as CEO of i³ Strategy Partners.

Why is Ann Cunningham’s appointment important for Alterity Therapeutics (ATHE)?

Her appointment adds significant commercial and strategic expertise as Alterity transitions toward late-stage development of ATH434 in Multiple System Atrophy. The company emphasizes her track record in launching blockbuster brands and shaping commercial strategies for innovative therapies in neurodegenerative diseases.

What is ATH434, Alterity Therapeutics’ lead asset mentioned in the filing?

ATH434 is Alterity’s lead drug candidate targeting neurodegenerative diseases, particularly Multiple System Atrophy. It has shown clinically meaningful efficacy in a randomized, double-blind, placebo-controlled Phase 2 trial and positive data in an open-label Phase 2 trial in participants with advanced Multiple System Atrophy.

What stage of development is Alterity Therapeutics (ATHE) in for Multiple System Atrophy?

Alterity is preparing to initiate a Phase 3 pivotal trial in Multiple System Atrophy, a rare and rapidly progressive neurodegenerative disease. Prior Phase 2 studies of ATH434 showed clinically meaningful efficacy and additional positive data in advanced-stage participants, supporting progression to late-stage development.

What other roles has Ann Cunningham held relevant to Alterity Therapeutics’ focus?

Cunningham previously served as Vice President of Neurodegenerative Disease and Psychiatry at Teva and held senior roles at Eli Lilly, leading psychiatry sales teams. She also serves on Vistagen Therapeutics’ Board and has been Chief Commercial Officer there, reinforcing her neuropsychiatry and commercial expertise.

Filing Exhibits & Attachments

1 document