Furnished
as Exhibit 99.1 to this Report on Form 6-K is a press release of ProQR Therapeutics N.V. (the “Company”) dated August
13, 2026, announcing the Company’s results for the three month period ended June 30, 2026.
On August 13, 2026 the Company issued a press release titled, “ProQR Announces Second Quarter 2026 Operating and Financial Results,”
announcing the Company’s results for the three month period ended June 30, 2026 and providing a business update. A copy of this press release
is attached hereto as Exhibit 99.1 and is incorporated herein by reference
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
Exhibit 99.1
ProQR Announces Second Quarter 2026
Operating and Financial Results
| · | First
clinical validation of Axiomer™ RNA editing established through NTCP modulation with
positive AX-0810 clinical target engagement data; full Phase 1 dataset to be presented at
a medical or scientific conference later this year |
| · | Multiple
clinical milestones, including initial AX-0811 Phase 1 data expected by year-end 2026, followed
in H1 2027 by: |
| · | biliary
atresia IIT initiation and initial data, |
| · | initial
AX-0422 (IDUA) patient data in MPS I Hurler syndrome, and |
| · | advancement
of AX-2911 (PNPLA3) to the clinic |
| · | Strengthened
balance sheet through $59.2 million financing during the quarter; ended Q2 2026 with €
117.1 million cash and cash equivalents, supporting runway through mid-2028 |
LEIDEN,
Netherlands & CAMBRIDGE, Mass., August 13, 2026 – ProQR Therapeutics N.V. (Nasdaq: PRQR) (ProQR), a clinical-stage
company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology
platform, today reported its financial and operating results for the second quarter ended June 30,
2026, and provided a business update.
“The second quarter marked an
important inflection point for ProQR as we established the first clinical validation of our Axiomer RNA editing platform by modulating
NTCP with AX-0810,” said Daniel A. de Boer, Founder and Chief Executive Officer of ProQR. “We believe these data, together
with the significant unmet need that remains in cholestatic liver diseases, including biliary atresia, support the continued advancement
of our NTCP franchise. Combined with our recent financing, we are well positioned to deliver a series of important clinical milestones,
including presentation of the full AX-0810 Phase 1 dataset later this year, initial Phase 1 data from AX-0811 by year end, initiation
of our biliary atresia clinical program and initial data in the first half of 2027, and continued advancement of our MPS I Hurler syndrome
and MASH programs. Together, these milestones reflect ProQR’s evolution into a multi-program clinical-stage RNA editing company,
strengthen the growing body of evidence supporting the broader potential of our Axiomer platform, and bring us closer to delivering transformative
RNA editing therapies for patients.”
Recent Progress and Anticipated Upcoming
Events
First Clinical Validation of Axiomer
and Next Milestones with NTCP Franchise
ProQR’s NTCP RNA editing approach
is designed to modulate NTCP and reduce bile acid uptake directly in hepatocytes, with the goal of reducing intrahepatic cholestasis.
In June, ProQR announced positive AX-0810
Phase 1 target engagement data from healthy volunteers, establishing the first clinical validation of the Company’s proprietary
Axiomer RNA editing platform. Key findings included:
| · | Up
to 8-fold increase in total serum bile acids (6 mg/kg) exceeding the Company’s pre-defined
2-fold threshold for meaningful NTCP modulation; |
| · | Dose-dependent
changes in conjugated bile acids, together with concordant changes in total serum bile acids
and TUDCA, supporting the therapeutic rationale that modulating NTCP reduces the accumulation
of toxic bile acids in the liver; |
| · | Favorable
safety and tolerability profile observed with AX-0810 to date, with no serious adverse events
or pruritus reported; pharmacokinetic findings to date support sustained target engagement,
including a half-life of eight weeks; and |
| · | Data
supporting advancement into patient study. |
ProQR plans to present the full dataset
from the Phase 1 study of AX-0810, including Cohort 3, at a medical or scientific conference later this year.
In July, the Company submitted a Clinical
Trial Application (CTA) to the European Medicines Agency (EMA) to initiate a Phase 1 clinical trial of AX-0811, its next-generation editing
oligonucleotide (EON) targeting NTCP for the treatment of cholestatic diseases. AX-0811 is generated by ProQR’s AI-enabled discovery
engine and demonstrated higher potency and longer durability than AX-0810 preclinically, which will lead to lower dose levels and less
frequent dosing in the clinic. Pending CTA authorization, initial data with AX-0811 is anticipated by year end 2026.
ProQR continues preparations for an
investigator-initiated trial (IIT) in pediatric biliary atresia in China, with initial clinical data expected in the first half of 2027.
Strengthened Financial Position
In June, ProQR closed an underwritten
registered direct offering of $50.0 million, alongside a concurrent private placement to an existing shareholder and strategic partner
Eli Lilly and Company (Lilly) of $9.2 million, for total gross proceeds of approximately $59.2 million. The financing further strengthened
the Company’s balance sheet providing runway into mid-2028, and is expected to support the continued advancement of its wholly
owned Axiomer RNA editing pipeline, including multiple anticipated clinical milestones.
Platform and Research Progress
ProQR
continues to strengthen the scientific foundation of its Axiomer RNA editing platform through ongoing research and publication of preclinical
findings. During the quarter, the Company’s preclinical research describing RNA editing of B4GALT1 was published online as a peer-reviewed
Journal Pre-proof in Molecular Therapy – Nucleic Acids. The publication
further expands the body of evidence supporting the breadth and versatility of the Axiomer platform beyond the Company’s clinical
pipeline.
Upcoming anticipated milestones
NTCP
franchise
| · | AX-0810
data from the 9 mg/kg cohort and 12-week follow up from the ongoing Phase 1 study expected
by year-end 2026 |
| · | AX-0811
initial data in healthy volunteers expected by year-end 2026, pending CTA authorization |
| · | IIT
in pediatric biliary atresia in China, with initial data targeted for first half of 2027 |
| · | Potentially
registration-enabling Phase 2 program, subject to regulatory interactions, expected to start
in mid-2027 with first interim analysis data expected by mid-2028 |
Other pipeline candidates
| · | AX-0422
for MPS I Hurler Syndrome (IDUA) CTA filing for a first-in-patient study anticipated in early
2027 and initial data expected in the first half of 2027 |
| · | AX-2911(PNPLA3)
FIH IIT in China expected in the first half of 2027 |
Partnership
| · | Continue
to execute on Lilly collaboration, with potential data updates and milestone payments |
Financial Highlights
At June 30, 2026, ProQR held cash
and cash equivalents of approximately € 117.1 million, compared to € 92.4 million at December 31, 2025. In June 2026,
the Company closed an underwritten registered direct offering of 27,624,310 ordinary shares and a concurrent private placement of 5,100,780
ordinary shares with Lilly for gross proceeds totaling approximately $59.2 million.
Net cash used in operating activities
during the second quarter ended June 30, 2026 was € 12.3 million, compared to € 11.4 million used for the same period
in 2025.
Research and development (R&D) costs
for the quarter ended June 30, 2026 were € 12.7 million, compared to € 11.4 million for the same period last year.
General and administrative costs for
the quarter ended June 30, 2026 were € 4.9 million, compared to € 4.8 million for the same period in 2025.
Net loss for the quarter ended June 30,
2026 was € 8.7 million, or € 0.08 per diluted share, compared to € 12.2 million, or € 0.12 per diluted share, for
the same period in 2025.
For further financial information for
the period ended June 30, 2026, please refer to our Q2 financial report filing available on our website, www.proqr.com under
Financials and Filings.
About Axiomer™
ProQR is pioneering a next-generation
RNA base editing technology called Axiomer™, which could potentially yield a new class of medicines for diverse types
of diseases. Axiomer™ “Editing Oligonucleotides”, or EONs, mediate single nucleotide changes to RNA in a
highly specific and targeted way using molecular machinery that is present in human cells called ADAR (Adenosine Deaminase Acting on
RNA). Axiomer™ EONs are designed to recruit and direct endogenously expressed ADARs to change an Adenosine (A) to
an Inosine (I) in the RNA – an Inosine is translated as a Guanosine (G) – correcting an RNA with a disease-causing
mutation back to a normal (wild type) RNA, modulating protein expression, or altering a protein so that it will have a new function that
helps prevent or treat disease.
About ProQR
ProQR Therapeutics is a clinical-stage
company dedicated to changing lives through the creation of transformative RNA therapies. ProQR is pioneering a next-generation RNA technology
called Axiomer™, which uses a cell’s own editing machinery called ADAR to make specific single nucleotide edits
in RNA to reverse a mutation or modulate protein expression and could potentially yield a new class of medicines for both rare and prevalent
diseases with unmet need. Based on our unique proprietary RNA repair platform technologies we are growing our pipeline with patients
and loved ones in mind.
Learn
more about ProQR at www.proqr.com.
Forward Looking Statements
This
press release contains forward-looking statements. All statements other than statements of historical fact are forward-looking statements,
which are often indicated by terms such as “continue,” "anticipate," "believe," "could," "estimate,"
"expect," "goal," "intend," "look forward to", "may," "plan," "potential,"
"predict," "project," "should," "will," "would" and similar expressions. Such forward-looking
statements include, but are not limited to, statements regarding our business, technology, strategy, preclinical and clinical model data;
our initial pipeline targets and the upcoming strategic priorities and milestones related thereto; the continued advancement of our lead
development pipeline programs, including ongoing and planned clinical trials; the ongoing Phase 1
clinical study of AX-0810 in NTCP for cholestatic diseases, including the timing and presentation of the full Phase 1 dataset, including
Cohort 3 and 12-week follow-up data, and the potential advancement into patient studies; our expectations regarding the safety, tolerability,
target engagement and potential therapeutic benefits of AX-0810; our ability to collaborate with investigators to initiate, conduct and
recruit for an IIT of our NTCP program in China in pediatric participants with biliary atresia and to generate meaningful data therefrom,
including the anticipated timing of initial data readout in H1 2027; the anticipated initiation of our registration-enabling Phase 2
program in mid-2027 with first interim analysis data expected by mid-2028, subject to regulatory interactions; our pipeline targets,
including the planned Phase 1 clinical trial of AX-0811 in healthy volunteers; our ability to obtain authorization for, initiate, enroll,
and complete a Phase 1 clinical trial for AX-0811 and the anticipated timing of initial data readout by year end 2026, pending CTA authorization;
the anticipated first-in-human study of AX-0422 targeting IDUA for MPS I Hurler syndrome, with a CTA filing expected in early 2027 and
anticipated initial clinical data readout in H1 2027; the anticipated IIT in China of AX-2911 targeting PNPLA3 for MASH in H1 2027; our
expectations regarding clinical updates across multiple programs in 2026 and 2027; the potential design, initiation and timing of a potentially
registration-enabling Phase 2 program for the NTCP franchise, subject to regulatory interactions; the therapeutic potential and development
timeline regarding AX-0810, AX-0811, AX-0422, and AX-2911;our participation at upcoming scientific conferences; the continued development
and advancement of our Axiomer platform; the therapeutic potential of our Axiomer RNA editing oligonucleotides and product candidates;
the timing, progress and results of our preclinical studies and other development and pipeline activities, including the release of data
related thereto; our patent estate, including our anticipated strength and our continued investment in it, as well as the timing of our
clinical development; the potential of our technologies and product candidates; the collaboration with Lilly and the intended benefits
thereof, including timing for data updates, and potential milestones; our ability to selectively form new partnerships and enter into
future collaborations; our financial position and expected cash-runway to fund our operations through mid 2028. Forward-looking statements
are based on management's beliefs and assumptions and on information available to management only as of the date of this press release.
Our actual results could differ materially from those expressed or implied by these forward-looking statements for many reasons, including,
without limitation, the risks, uncertainties and other factors in our filings made with the Securities and Exchange Commission, including
certain sections of our most recent annual report filed on Form 20-F. These risks and uncertainties include, among others, risks
and uncertainties associated with conducting IITs in China, including evolving regulatory requirements, the cost, timing and results
of preclinical studies and clinical trials and other development activities by us and our collaborative partners whose operations and
activities may be slowed or halted due to shortage and pressure on supply chains and logistics in the global market, economic sanctions
and international tariffs; the likelihood of our preclinical and clinical programs being initiated and executed on timelines provided
and our reliance on our contract research organizations and predictability of timely enrollment of subjects and patients to advance our
clinical trials and maintain their own operations; our reliance on contract manufacturers to supply materials for research and development
and the risk of supply interruption from a contract manufacturer; the potential for future data to alter initial and preliminary results
of early-stage clinical trials; the unpredictability of the duration and results of the regulatory review of applications or clearances
that are necessary to initiate and continue to advance and progress our clinical programs; the ability to secure, maintain and realize
the intended benefits of collaborations with partners, including the collaboration with Lilly; the possible impairment of, inability
to obtain, and costs to obtain intellectual property rights; possible safety or efficacy concerns that could emerge as new data are generated
in research and development; general business, operational, financial and accounting risks, and risks related to litigation and disputes
with third parties; and risks related to macroeconomic conditions and market volatility resulting from global economic developments,
geopolitical events and conflicts, inflationary pressures, fluctuating interest rates, tariffs and potential for significant changes
in U.S. policies and regulatory environment. Given these risks, uncertainties and other factors, you should not place undue reliance
on these forward-looking statements, and we assume no obligation to update these forward-looking statements, even if new information
becomes available in the future, except as required by law.
ProQR Therapeutics N.V.
Investor
and media contact:
Sarah Kiely
ProQR Therapeutics N.V.
T: +1 617 599 6228
skiely@proqr.com
or
Investor contact:
Peter Kelleher
LifeSci Advisors
T: +1 617 430 7579
pkelleher@lifesciadvisors.com
PROQR THERAPEUTICS N.V.
Unaudited Interim Condensed Consolidated Statement of Financial Position
| | |
June 30, | | |
December 31, | |
| | |
2026 | | |
2025 | |
| | |
€1,000 | | |
€1,000 | |
| Assets | |
| | | |
| | |
| Property, plant and equipment | |
| 11,923 | | |
| 12,630 | |
| Investments in financial assets | |
| — | | |
| — | |
| Non-current assets | |
| 11,923 | | |
| 12,630 | |
| | |
| | | |
| | |
| Cash and cash equivalents | |
| 117,125 | | |
| 92,413 | |
| Trade and other receivables | |
| 3,908 | | |
| 6,800 | |
| Other taxes | |
| 597 | | |
| 913 | |
| Current assets | |
| 121,630 | | |
| 100,126 | |
| Total assets | |
| 133,553 | | |
| 112,756 | |
| | |
| | | |
| | |
| Equity and liabilities | |
| | | |
| | |
| Equity | |
| | | |
| | |
| Equity attributable to owners of the Company | |
| 79,477 | | |
| 49,374 | |
| Total equity | |
| 79,477 | | |
| 49,374 | |
| | |
| | | |
| | |
| Liabilities | |
| | | |
| | |
| Borrowings | |
| — | | |
| — | |
| Lease liabilities | |
| 8,692 | | |
| 9,547 | |
| Deferred income | |
| 10,510 | | |
| 21,394 | |
| Non-current liabilities | |
| 19,202 | | |
| 30,941 | |
| | |
| | | |
| | |
| Borrowings | |
| 5,017 | | |
| 4,872 | |
| Lease liabilities | |
| 1,603 | | |
| 1,545 | |
| Derivative financial instruments | |
| 213 | | |
| 234 | |
| Trade payables | |
| — | | |
| 298 | |
| Social securities and other taxes | |
| 214 | | |
| — | |
| Deferred income | |
| 17,644 | | |
| 17,552 | |
| Other current liabilities | |
| 10,183 | | |
| 7,940 | |
| Current liabilities | |
| 34,874 | | |
| 32,441 | |
| Total liabilities | |
| 54,076 | | |
| 63,382 | |
| | |
| | | |
| | |
| Total equity and liabilities | |
| 133,553 | | |
| 112,756 | |
PROQR THERAPEUTICS N.V.
Unaudited Interim Condensed Consolidated Statement of Profit or Loss and Other Comprehensive Income
(€ in thousands, except share and
per share data)
| | |
Three month period | | |
Six month period | |
| | |
ended June 30, | | |
ended June 30, | |
| | |
2026 | | |
2025 | | |
2026 | | |
2025 | |
| | |
€1,000 | | |
€1,000 | | |
€1,000 | | |
€1,000 | |
| Revenue | |
| 8,759 | | |
| 3,817 | | |
| 10,792 | | |
| 8,336 | |
| | |
| | | |
| | | |
| | | |
| | |
| Other income | |
| — | | |
| 158 | | |
| — | | |
| 380 | |
| | |
| | | |
| | | |
| | | |
| | |
| Research and development costs | |
| (12,667 | ) | |
| (11,408 | ) | |
| (24,497 | ) | |
| (23,731 | ) |
| General and administrative costs | |
| (4,914 | ) | |
| (4,816 | ) | |
| (8,766 | ) | |
| (8,050 | ) |
| Total operating costs | |
| (17,581 | ) | |
| (16,224 | ) | |
| (33,263 | ) | |
| (31,781 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Operating result | |
| (8,822 | ) | |
| (12,249 | ) | |
| (22,471 | ) | |
| (23,065 | ) |
| Finance income and expense | |
| 152 | | |
| 192 | | |
| 364 | | |
| 647 | |
| Results related to financial liabilities measured at fair value through profit or loss | |
| (33 | ) | |
| (104 | ) | |
| 21 | | |
| 178 | |
| | |
| | | |
| | | |
| | | |
| | |
| Result before corporate income taxes | |
| (8,703 | ) | |
| (12,161 | ) | |
| (22,086 | ) | |
| (22,240 | ) |
| Income taxes | |
| (25 | ) | |
| (18 | ) | |
| (25 | ) | |
| (18 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Result for the period | |
| (8,728 | ) | |
| (12,179 | ) | |
| (22,111 | ) | |
| (22,258 | ) |
| Other comprehensive income (foreign exchange differences on foreign operation) | |
| 48 | | |
| (682 | ) | |
| 227 | | |
| (1,053 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Total comprehensive income | |
| (8,680 | ) | |
| (12,861 | ) | |
| (21,884 | ) | |
| (23,311 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Result attributable to | |
| | | |
| | | |
| | | |
| | |
| Owners of the Company | |
| (8,728 | ) | |
| (12,179 | ) | |
| (22,111 | ) | |
| (22,258 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Total comprehensive income attributable to | |
| | | |
| | | |
| | | |
| | |
| Owners of the Company | |
| (8,680 | ) | |
| (12,861 | ) | |
| (21,884 | ) | |
| (23,311 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Share information | |
| | | |
| | | |
| | | |
| | |
| Weighted average number of shares outstanding1 | |
| 109,958,613 | | |
| 105,343,897 | | |
| 107,673,118 | | |
| 105,320,495 | |
| | |
| | | |
| | | |
| | | |
| | |
| Earnings per share attributable to owners of the Company (Euro per share) | |
| | | |
| | | |
| | | |
| | |
| Basic loss per share1 | |
| (0.08 | ) | |
| (0.12 | ) | |
| (0.21 | ) | |
| (0.21 | ) |
| Diluted loss per share1 | |
| (0.08 | ) | |
| (0.12 | ) | |
| (0.21 | ) | |
| (0.21 | ) |
| 1. | For
these periods the potential exercise of share options is not included in the diluted earnings
per share as the Company was loss-making. Due to the anti-dilutive nature of the outstanding
options, basic and diluted earnings per share are equal. |
PROQR THERAPEUTICS N.V.
Unaudited Interim Condensed Consolidated Statement of Changes in Equity
| | |
Attributable to owners of the Company | |
| | |
Number of shares | | |
Share Capital | | |
Share Premium | | |
Equity settled Employee Benefit Reserve | | |
Translation Reserve | | |
Accumulated Deficit | | |
Total Equity | |
| | |
| | |
€1,000 | | |
€1,000 | | |
€1,000 | | |
€1,000 | | |
€1,000 | | |
€1,000 | |
| Balance at January 1, 2025 | |
107,710,916 | | |
4,308 | | |
483,812 | | |
26,248 | | |
1,350 | | |
(427,158 | ) | |
88,560 | |
| Result for the period | |
— | | |
— | | |
— | | |
— | | |
— | | |
(22,258 | ) | |
(22,258 | ) |
| Other comprehensive income | |
— | | |
— | | |
— | | |
— | | |
(1,053 | ) | |
— | | |
(1,053 | ) |
| Recognition of share-based payments | |
— | | |
— | | |
— | | |
1,667 | | |
— | | |
— | | |
1,667 | |
| Treasury shares transferred | |
(131,525 | ) | |
— | | |
— | | |
— | | |
— | | |
— | | |
— | |
| Share options lapsed | |
— | | |
— | | |
— | | |
(1,462 | ) | |
— | | |
1,462 | | |
— | |
| Share options exercised / RSUs vested | |
131,525 | | |
— | | |
67 | | |
(181 | ) | |
— | | |
181 | | |
67 | |
| | |
| | |
| | |
| | |
| | |
| | |
| | |
| |
| Balance at June 30, 2025 | |
107,710,916 | | |
4,308 | | |
483,879 | | |
26,272 | | |
297 | | |
(447,773 | ) | |
66,983 | |
| | |
| | |
| | |
| | |
| | |
| | |
| | |
| |
| Balance at January 1, 2026 | |
107,710,916 | | |
4,308 | | |
483,881 | | |
28,426 | | |
265 | | |
(467,506 | ) | |
49,374 | |
| Result for the period | |
— | | |
— | | |
— | | |
— | | |
— | | |
(22,111 | ) | |
(22,111 | ) |
| Other comprehensive income | |
— | | |
— | | |
— | | |
— | | |
227 | | |
— | | |
227 | |
| Recognition of share-based payments | |
— | | |
— | | |
— | | |
2,786 | | |
— | | |
— | | |
2,786 | |
| Issuance of ordinary shares | |
35,755,393 | | |
1,430 | | |
47,771 | | |
— | | |
— | | |
— | | |
49,201 | |
| Treasury shares transferred | |
(4,623 | ) | |
— | | |
— | | |
— | | |
— | | |
— | | |
— | |
| Share options lapsed | |
— | | |
— | | |
— | | |
(2,199 | ) | |
— | | |
2,199 | | |
— | |
| Share options exercised / RSUs vested | |
4,623 | | |
— | | |
— | | |
(6 | ) | |
— | | |
6 | | |
— | |
| | |
| | |
| | |
| | |
| | |
| | |
| | |
| |
| Balance at June 30, 2026 | |
143,466,309 | | |
5,738 | | |
531,652 | | |
29,007 | | |
492 | | |
(487,412 | ) | |
79,477 | |
PROQR THERAPEUTICS N.V.
Unaudited Interim Condensed Consolidated Statement of Cash Flows
| | |
Three month period | | |
Six month period | |
| | |
ended June 30, | | |
ended June 30, | |
| | |
2026 | | |
2025 | | |
2026 | | |
2025 | |
| | |
€1,000 | | |
€1,000 | | |
€1,000 | | |
€1,000 | |
| Cash flows from operating activities | |
| | | |
| | | |
| | | |
| | |
| Net result | |
| (8,728 | ) | |
| (12,179 | ) | |
| (22,111 | ) | |
| (22,258 | ) |
| Adjustments for: | |
| | | |
| | | |
| | | |
| | |
| — Other income | |
| — | | |
| (158 | ) | |
| — | | |
| (380 | ) |
| — Depreciation | |
| 707 | | |
| 675 | | |
| 1,401 | | |
| 1,353 | |
| — Share-based compensation | |
| 1,358 | | |
| 909 | | |
| 2,786 | | |
| 1,667 | |
| — Financial income and expenses | |
| (110 | ) | |
| (139 | ) | |
| (369 | ) | |
| (647 | ) |
| — Results related to financial liabilities measured at fair value through profit or loss | |
| 33 | | |
| 104 | | |
| (21 | ) | |
| (178 | ) |
| — Income tax expenses | |
| 25 | | |
| 18 | | |
| 25 | | |
| 18 | |
| | |
| | | |
| | | |
| | | |
| | |
| Changes in working capital | |
| (5,754 | ) | |
| (1,178 | ) | |
| (5,645 | ) | |
| (7,900 | ) |
| Cash used in operations | |
| (12,469 | ) | |
| (11,948 | ) | |
| (23,934 | ) | |
| (28,325 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Corporate income tax (paid)/received | |
| (25 | ) | |
| (18 | ) | |
| (25 | ) | |
| (18 | ) |
| Interest received | |
| 359 | | |
| 617 | | |
| 726 | | |
| 1,405 | |
| Interest paid | |
| (135 | ) | |
| (52 | ) | |
| (182 | ) | |
| (261 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Net cash used in operating activities | |
| (12,270 | ) | |
| (11,401 | ) | |
| (23,415 | ) | |
| (27,199 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Cash flow from investing activities | |
| | | |
| | | |
| | | |
| | |
| Purchases of property, plant and equipment | |
| (291 | ) | |
| (101 | ) | |
| (455 | ) | |
| (325 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Net cash used in investing activities | |
| (291 | ) | |
| (101 | ) | |
| (455 | ) | |
| (325 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Cash flows from financing activities | |
| | | |
| | | |
| | | |
| | |
| Proceeds from issuance of shares, net | |
| 49,201 | | |
| — | | |
| 49,201 | | |
| — | |
| Proceeds from exercise of share options | |
| — | | |
| — | | |
| — | | |
| 67 | |
| Repayment of lease liability | |
| (621 | ) | |
| (293 | ) | |
| (925 | ) | |
| (860 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Net cash generated by / (used in) financing activities | |
| 48,580 | | |
| (293 | ) | |
| 48,276 | | |
| (793 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Net increase / (decrease) in cash and cash equivalents | |
| 36,019 | | |
| (11,795 | ) | |
| 24,406 | | |
| (28,317 | ) |
| | |
| | | |
| | | |
| | | |
| | |
| Currency effect cash and cash equivalents | |
| 18 | | |
| (854 | ) | |
| 306 | | |
| (1,326 | ) |
| Cash and cash equivalents, at beginning of the period | |
| 81,088 | | |
| 132,414 | | |
| 92,413 | | |
| 149,408 | |
| | |
| | | |
| | | |
| | | |
| | |
| Cash and cash equivalents at the end of the period | |
| 117,125 | | |
| 119,765 | | |
| 117,125 | | |
| 119,765 | |