Personalis (PSNL) 10% holder Tempus AI reports open-market share buys

Rhea-AI Filing Summary

Tempus AI, Inc., a 10% owner of Personalis, Inc., reported a series of open-market purchases of Personalis common stock. Between November 18 and December 22, 2025, Tempus AI bought multiple blocks of shares at weighted-average prices generally between $7.67 and $11.00, as detailed in the transaction table and footnotes.

After the latest reported trade on December 22, 2025, Tempus AI beneficially owned 13,039,067 shares of Personalis common stock, held directly. The footnotes explain that each reported price is a weighted average for numerous trades within stated intraday price ranges.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Tempus AI, Inc.

(Last) (First) (Middle)

600 WEST CHICAGO AVENUE

SUITE 510

(Street)

CHICAGO IL 60654

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Personalis, Inc. [ PSNL ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
11/18/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	11/18/2025		P		64,750(1)	A	$7.67(1)	12,783,550	D
Common Stock	11/19/2025		P		30,645(2)	A	$8.12(2)	12,814,195	D
Common Stock	11/20/2025		P		28,827(3)	A	$8.63(3)	12,843,022	D
Common Stock	11/21/2025		P		9,900(4)	A	$8.84(4)	12,852,922	D
Common Stock	11/21/2025		P		16,599(5)	A	$9.74(5)	12,869,521	D
Common Stock	11/24/2025		P		25,225(6)	A	$9.87(6)	12,894,746	D
Common Stock	11/25/2025		P		9,712(7)	A	$10.08(7)	12,904,458	D
Common Stock	11/25/2025		P		13,888(8)	A	$11(8)	12,918,346	D
Common Stock	12/17/2025		P		31,650(9)	A	$7.86(9)	12,949,996	D
Common Stock	12/18/2025		P		31,430(10)	A	$7.91(10)	12,981,426	D
Common Stock	12/19/2025		P		29,641(11)	A	$8.39(11)	13,011,067	D
Common Stock	12/22/2025		P		28,000(12)	A	$8.93(12)	13,039,067	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $7.36 to $7.88, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

2. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $7.80 to $8.40, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

3. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $8.28 to $9.10, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

4. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $8.40 to $9.40, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

5. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $9.48 to $9.85, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

6. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $9.69 to $10.12, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

7. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $9.47 to $10.46, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

8. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $10.47 to $11.23, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

9. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $7.75 to $7.93, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

10. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $7.80 to $8.38, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

11. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $8.09 to $8.63, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

12. This price reflects the weighted average price at which these shares were purchased. The shares were purchased in multiple transactions at prices ranging from $8.73 to $9.08, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote.

	Tempus AI, Inc. By: /s/ Andrew Polovin, General Counsel	02/13/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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FAQ

What insider activity did Tempus AI report in Personalis (PSNL) stock?

Tempus AI, Inc. reported multiple open-market purchases of Personalis common stock between November 18 and December 22, 2025. Each transaction added shares, increasing its directly held beneficial ownership as disclosed in the Form 4 filing’s non-derivative securities table.

How many Personalis shares does Tempus AI own after these Form 4 transactions?

After the most recent reported transaction on December 22, 2025, Tempus AI beneficially owned 13,039,067 shares of Personalis common stock. This figure reflects direct ownership following the latest open-market purchase shown in the Form 4 transaction table.

Were Tempus AI’s Personalis (PSNL) trades open-market purchases or sales?

All reported transactions are coded “P,” indicating open-market or private purchases of Personalis common stock. The insider filing’s normalized data also labels each transaction as a buy and describes the action as an open-market purchase rather than a sale.

Over what period did Tempus AI buy Personalis shares according to this Form 4?

The reported buying period runs from November 18, 2025 through December 22, 2025. During these dates, Tempus AI executed a series of separate purchases, each recorded with its own trade date, share amount, and weighted-average purchase price per share.

At what prices did Tempus AI purchase Personalis common stock?

Reported weighted-average purchase prices range from $7.67 to $11.00 per share across the individual transactions. Footnotes clarify that each price is an average of multiple trades executed within specified intraday ranges, such as $7.36–$7.88 and $10.47–$11.23.

Does Tempus AI hold its Personalis (PSNL) shares directly or indirectly?

The Form 4 identifies Tempus AI’s ownership of Personalis common stock as direct, marked with ownership code “D.” The filing does not describe any indirect holding entity or intermediary structure in the nature-of-ownership column for these reported transactions.