Insider plans sale of 46,203 company shares

Asif Ali has filed a notice of proposed sale of 46,203 shares of common stock through Morgan Stanley Smith Barney, with an aggregate market value of $3,841,128.28, to be sold on the NASDAQ on or about January 27, 2026.

Rhea-AI Filing Summary

Asif Ali has filed a notice of proposed sale of 46,203 shares of common stock through Morgan Stanley Smith Barney, with an aggregate market value of $3,841,128.28, to be sold on the NASDAQ on or about January 27, 2026.

The filing notes that 62,515,666 shares of the same class were outstanding, providing context for the size of the planned sale. In the prior three months, Asif Ali sold 8,588 common shares for gross proceeds of $708,327.08. The form includes a representation that the seller is not aware of undisclosed material adverse information about the issuer’s operations.

FAQ

How many PTGX common shares does Asif Ali plan to sell under this Form 144?

Asif Ali plans to sell 46,203 common shares under this notice. The planned sale has an aggregate market value of $3,841,128.28 and is expected to be executed on the NASDAQ around January 27, 2026, subject to Rule 144 conditions.

What is the aggregate market value of the PTGX shares in Asif Ali’s planned Rule 144 sale?

The aggregate market value of the 46,203 common shares is $3,841,128.28. This value is based on market pricing at the time of the notice and reflects the total dollar amount potentially realized if all proposed shares are sold as indicated.

How many PTGX shares were outstanding relative to Asif Ali’s planned Form 144 sale?

There were 62,515,666 common shares outstanding for this class. This provides a baseline to gauge the relative size of the 46,203-share proposed sale, which represents a small portion of the total shares outstanding disclosed in the notice.

What PTGX share sales has Asif Ali made in the last three months?

Over the past three months, Asif Ali sold 8,588 common shares. These sales generated gross proceeds of $708,327.08. The Form 144 requires disclosure of such recent sales to show other transactions that must be aggregated under Rule 144 limits.

How were the PTGX securities that Asif Ali plans to sell originally acquired?

The shares were mainly acquired as restricted stock from the issuer on several dates in 2025 and 2026, plus 28,000 shares from a stock option exercise paid in cash on January 27, 2026, as detailed in the acquisition table.

Which broker is handling Asif Ali’s planned PTGX share sale under Rule 144?

The planned sale will be handled by Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, 8th Floor, New York, NY 10004. The transaction is listed as taking place on the NASDAQ exchange.

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Accepted by SEC EDGAR 01/27/2026 - 05:12 PM Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0001921163
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	PROTAGONIST THERAPEUTICS, INC.
SEC File Number	001-37852
Address of Issuer	7707 Gateway Boulevard, Suite 140 Newark CALIFORNIA 94560-1160
Phone	(510) 474-0170
Name of Person for Whose Account the Securities are To Be Sold	ASIF ALI
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	46203	3841128.28	62515666	01/27/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	01/15/2026	Restricted Stock	Issuer			3975	01/15/2026	Not Applicable
Common	01/15/2025	Restricted Stock	Issuer			2225	01/15/2025	Not Applicable
Common	04/18/2025	Restricted Stock	Issuer			1682	04/18/2025	Not Applicable
Common	01/15/2026	Restricted Stock	Issuer			3712	01/15/2026	Not Applicable
Common	01/15/2026	Restricted Stock	Issuer			2211	01/15/2026	Not Applicable
Common	01/15/2025	Restricted Stock	Issuer			4398	01/15/2025	Not Applicable
Common	01/27/2026	Stock Option Exercise	Issuer			28000	01/27/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
ASIF ALI 7707 Gateway Boulevard, Suite 140 Newark CA 94560-1160	Common	01/20/2026	8588	708327.08

144: Remarks and Signature

Remarks
Date of Notice	01/27/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ Asif Ali
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)