[Form 4] uniQure N.V. Insider Trading Activity

Rhea-AI Filing Summary

Director Madhavan Balachandran of uniQure reported a non-discretionary sale of 2,112 ordinary shares on June 20, 2025 at a weighted average price of $14.45 per share (range: $14.40-$14.50). The transaction was executed to cover estimated tax withholdings following the vesting of restricted share units, in accordance with automatic sale instructions in the Restricted Share Unit Agreement.

Following the reported transaction, Balachandran continues to hold 37,697 ordinary shares directly. The sale was conducted through a pre-arranged automatic selling plan and was not a discretionary trade by the reporting person.

• Transaction Code: S (Sale)
• Ownership Form: Direct (D)
• Transaction was executed pursuant to automatic sale instructions
• Filing was signed by Christian Klemt as Attorney-in-Fact on June 24, 2025

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Balachandran Madhavan

(Last) (First) (Middle)

C/O UNIQURE N.V.

PAASHEUVELWEG 25A

(Street)

AMSTERDAM P7 11058BP

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
uniQure N.V. [ QURE ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
06/20/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	06/20/2025		S(1)		2,112(1)	D	$14.45(2)	37,697	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person.

2. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $14.40 to $14.50. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

	/s/ Christian Klemt, Attorney-in-Fact	06/24/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many QURE shares did insider Balachandran Madhavan sell on June 20, 2025?

Director Balachandran Madhavan sold 2,112 ordinary shares of QURE on June 20, 2025 at a weighted average price of $14.45 per share.

What was the purpose of Madhavan's QURE share sale in June 2025?

The shares were sold automatically upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions in the Restricted Share Unit Agreement. This was not a discretionary trade by the insider.

How many QURE shares does Balachandran Madhavan own after the June 2025 transaction?

Following the reported transaction, Balachandran Madhavan directly owns 37,697 ordinary shares of QURE.

What was the price range of QURE shares sold in Madhavan's June 2025 transaction?

The shares were sold in multiple transactions at prices ranging from $14.40 to $14.50, with a weighted average price of $14.45 per share.

What is Balachandran Madhavan's role at QURE?

According to the Form 4 filing, Balachandran Madhavan serves as a Director of uniQure N.V.