Uniqure Financials
This page shows Uniqure (QURE) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 12 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
uniQure remains a capital-funded R&D enterprise, with customer revenue too small to absorb its recurring operating burn.
The move from negative equity in FY2024 to positive equity in FY2025 looks more like a recapitalization than a self-funded recovery, because the balance sheet improved while the core business kept consuming cash. Shares outstanding rose27.3% and financing supplied$415.4M , even though operating cash flow stayed deeply negative and revenue remained small.
Revenue of
The cash burn is operating-driven, not capex-driven: operating cash outflow of
Financial Health Signals
Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →
Health score ≠ stock price. This rates the quality of Uniqure's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.
Uniqure scores 0.82, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($3.1B) relative to total liabilities ($626.0M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.
Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.
Uniqure passes 4 of 9 financial strength tests. 2 of 4 profitability signals pass, 2 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.
For every $1 of reported earnings, Uniqure generates $0.89 in operating cash flow (-$178.0M OCF vs -$199.0M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.
Uniqure earns $-3.0 in operating income for every $1 of interest expense (-$185.3M vs $62.0M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.
Key Financial Metrics
Earnings & Revenue
Uniqure generated $16.1M in revenue in fiscal year 2025. This represents a decrease of 40.6% from the prior year.
Uniqure's EBITDA was -$170.6M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 0.6% from the prior year.
Uniqure reported -$199.0M in net income in fiscal year 2025. This represents an increase of 16.9% from the prior year.
Uniqure earned $-3.46 per diluted share (EPS) in fiscal year 2025. This represents an increase of 29.7% from the prior year.
Cash & Balance Sheet
Uniqure generated -$178.4M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 4.1% from the prior year.
Uniqure held $80.2M in cash against $49.7M in long-term debt as of fiscal year 2025.
Uniqure had 62M shares outstanding in fiscal year 2025. This represents an increase of 27.2% from the prior year.
Margins & Returns
Uniqure's gross margin was 89.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is down 5.8 percentage points from the prior year.
Uniqure's operating margin was -1151.4% in fiscal year 2025, reflecting core business profitability. This is down 471.8 percentage points from the prior year.
Uniqure's net profit margin was -1236.2% in fiscal year 2025, showing the share of revenue converted to profit. This is down 352.7 percentage points from the prior year.
Uniqure's ROE was -100.0% in fiscal year 2025, measuring profit generated per dollar of shareholder equity.
Capital Allocation
Uniqure invested $140.7M in research and development in fiscal year 2025. This represents a decrease of 2.2% from the prior year.
Uniqure invested $439K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 87.0% from the prior year.
QURE Income Statement
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $3.6M-36.0% | $5.6M+50.4% | $3.7M-29.7% | $5.3M+235.8% | $1.6M-70.0% | $5.2M+128.3% | $2.3M-79.4% | $11.1M |
| Cost of Revenue | $219K-49.7% | $435K+9.3% | $398K-39.3% | $656K+233.0% | $197K-68.2% | $619K+134.5% | $264K+12.8% | $234K |
| Gross Profit | $3.3M-34.9% | $5.1M+55.4% | $3.3M-28.3% | $4.6M+236.2% | $1.4M-70.2% | $4.6M+127.5% | $2.0M-81.4% | $10.9M |
| R&D Expenses | $29.2M-16.1% | $34.8M+1.2% | $34.4M-2.9% | $35.4M-2.1% | $36.1M-7.0% | $38.8M+26.9% | $30.6M-9.1% | $33.7M |
| SG&A Expenses | $20.1M-7.1% | $21.6M+11.2% | $19.4M+44.0% | $13.5M+23.8% | $10.9M-4.1% | $11.4M-1.7% | $11.6M-26.6% | $15.8M |
| Operating Income | -$45.7M+10.6% | -$51.1M-0.2% | -$51.0M-16.3% | -$43.9M-11.5% | -$39.3M+14.2% | -$45.8M-13.9% | -$40.2M+8.6% | -$44.0M |
| Interest Expense | $14.0M-3.7% | $14.6M-12.8% | $16.7M+7.2% | $15.6M+3.2% | $15.1M+1.6% | $14.9M-10.4% | $16.6M+2.8% | $16.2M |
| Income Tax | $488K+112.5% | -$3.9M-145.4% | $8.6M+1929.6% | $425K-14.3% | $496K-42.1% | $856K+2861.3% | -$31K-103.3% | $948K |
| Net Income | -$53.5M-44.2% | -$37.1M+53.9% | -$80.5M-113.5% | -$37.7M+13.6% | -$43.6M+40.5% | -$73.3M-65.2% | -$44.4M+21.2% | -$56.3M |
| EPS (Diluted) | $-0.85 | N/A | $-1.38-100.0% | $-0.69+15.9% | $-0.82 | N/A | $-0.91+21.6% | $-1.16 |
QURE Balance Sheet
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $778.7M-5.6% | $824.9M-7.1% | $888.4M+51.9% | $584.9M-3.4% | $605.4M+8.8% | $556.5M-13.8% | $645.8M-11.6% | $730.8M |
| Current Assets | $615.7M-6.1% | $656.0M-8.4% | $716.2M+75.3% | $408.6M-6.2% | $435.4M+11.6% | $390.3M-15.9% | $464.1M-21.6% | $592.0M |
| Cash & Equivalents | $140.0M+74.5% | $80.2M-86.6% | $597.1M+135.3% | $253.8M+16.8% | $217.2M+36.7% | $158.9M-36.8% | $251.6M-12.6% | $287.9M |
| Inventory | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Accounts Receivable | $3.6M-39.2% | $5.9M | N/A | N/A | N/A | N/A | N/A | N/A |
| Goodwill | $24.8M-2.1% | $25.4M+0.1% | $25.3M-0.1% | $25.3M+8.5% | $23.4M+4.2% | $22.4M-6.9% | $24.1M+4.2% | $23.1M |
| Total Liabilities | $629.4M+0.5% | $626.0M-5.1% | $659.6M+12.0% | $588.9M+3.0% | $571.7M+1.5% | $563.3M-4.5% | $590.0M-6.9% | $633.7M |
| Current Liabilities | $59.2M-5.9% | $62.9M-37.5% | $100.6M+145.9% | $40.9M+12.7% | $36.3M-9.3% | $40.1M-43.8% | $71.3M-11.4% | $80.5M |
| Long-Term Debt | $49.9M+0.5% | $49.7M-4.2% | $51.9M+0.1% | $51.8M+0.5% | $51.6M+0.5% | $51.3M+0.4% | $51.1M-50.1% | $102.5M |
| Total Equity | $149.3M-24.9% | $198.9M-13.0% | $228.7M+5814.4% | -$4.0M-111.9% | $33.7M+598.9% | -$6.8M-112.1% | $55.8M-42.5% | $97.1M |
| Retained Earnings | -$1.4B-4.0% | -$1.3B-2.9% | -$1.3B-6.6% | -$1.2B-3.2% | -$1.2B-3.9% | -$1.1B-6.9% | -$1.1B-4.4% | -$1.0B |
QURE Cash Flow Statement
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$38.2M+50.7% | -$77.6M-373.0% | -$16.4M+58.9% | -$39.9M+9.5% | -$44.1M+16.5% | -$52.8M-44.4% | -$36.6M-11.9% | -$32.7M |
| Capital Expenditures | $140K+17.6% | $119K+280.3% | -$66K-125.4% | $260K+106.3% | $126K+215.0% | $40K-89.5% | $380K-37.1% | $604K |
| Free Cash Flow | -$38.4M+50.6% | -$77.7M-371.8% | -$16.5M+59.0% | -$40.2M+9.2% | -$44.2M+16.4% | -$52.9M-43.0% | -$37.0M-11.0% | -$33.3M |
| Investing Cash Flow | $98.6M+122.3% | -$441.4M-1760.6% | $26.6M-63.6% | $73.1M+263.6% | $20.1M+175.5% | -$26.6M-155.9% | $47.7M-38.8% | $77.9M |
| Financing Cash Flow | $550K-77.5% | $2.4M-99.3% | $332.2M+754979.5% | $44K-99.9% | $80.7M+1337.8% | -$6.5M+87.7% | -$53.0M | N/A |
| Dividends Paid | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Share Buybacks | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
QURE Financial Ratios
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 |
|---|---|---|---|---|---|---|---|---|
| Gross Margin | 93.8%+1.7pp | 92.2%+2.9pp | 89.3%+1.7pp | 87.5%+0.1pp | 87.4%-0.7pp | 88.1%-0.3pp | 88.5%-9.4pp | 97.9% |
| Operating Margin | -1283.5%-365.5pp | -918.1%+460.9pp | -1379.0%-545.3pp | -833.6%+1676.3pp | -2510.0%-1632.2pp | -877.8%+881.2pp | -1759.0%-1363.4pp | -395.6% |
| Net Margin | -1503.0%-836.4pp | -666.6%+1509.3pp | -2175.9%-1459.1pp | -716.8%+2067.9pp | -2784.8%-1380.7pp | -1404.0%+536.4pp | -1940.4%-1434.4pp | -506.0% |
| Return on Equity | -35.9%-17.2pp | -18.7%+16.5pp | -35.2% | N/A | -129.5% | N/A | -79.5%-21.5pp | -58.0% |
| Return on Assets | -6.9%-2.4pp | -4.5%+4.6pp | -9.1%-2.6pp | -6.5%+0.8pp | -7.2%+6.0pp | -13.2%-6.3pp | -6.9%+0.8pp | -7.7% |
| Current Ratio | 10.40-0.0 | 10.43+3.3 | 7.12-2.9 | 9.98-2.0 | 11.99+2.2 | 9.74+3.2 | 6.51-0.8 | 7.36 |
| Debt-to-Equity | 0.33+0.1 | 0.25+0.0 | 0.23+13.2 | -12.95-14.5 | 1.53+9.1 | -7.60-8.5 | 0.92-0.1 | 1.06 |
| FCF Margin | -1077.6%+317.7pp | -1395.3%-950.4pp | -444.9%+318.2pp | -763.1%+2059.2pp | -2822.3%-1809.4pp | -1012.9%+604.0pp | -1616.9%-1317.5pp | -299.4% |
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Frequently Asked Questions
What is Uniqure's annual revenue?
Uniqure (QURE) reported $16.1M in total revenue for fiscal year 2025. This represents a -40.6% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is Uniqure's revenue growing?
Uniqure (QURE) revenue declined by 40.6% year-over-year, from $27.1M to $16.1M in fiscal year 2025.
Is Uniqure profitable?
No, Uniqure (QURE) reported a net income of -$199.0M in fiscal year 2025, with a net profit margin of -1236.2%.
What is Uniqure's EBITDA?
Uniqure (QURE) had EBITDA of -$170.6M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
How much debt does Uniqure have?
As of fiscal year 2025, Uniqure (QURE) had $80.2M in cash and equivalents against $49.7M in long-term debt.
What is Uniqure's gross margin?
Uniqure (QURE) had a gross margin of 89.5% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.
What is Uniqure's operating margin?
Uniqure (QURE) had an operating margin of -1151.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.
What is Uniqure's net profit margin?
Uniqure (QURE) had a net profit margin of -1236.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.
What is Uniqure's return on equity (ROE)?
Uniqure (QURE) has a return on equity of -100.0% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Uniqure's free cash flow?
Uniqure (QURE) generated -$178.4M in free cash flow during fiscal year 2025. This represents a 4.1% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Uniqure's operating cash flow?
Uniqure (QURE) generated -$178.0M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.
What are Uniqure's total assets?
Uniqure (QURE) had $824.9M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Uniqure's capital expenditures?
Uniqure (QURE) invested $439K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.
How much does Uniqure spend on research and development?
Uniqure (QURE) invested $140.7M in research and development during fiscal year 2025.
What is Uniqure's current ratio?
Uniqure (QURE) had a current ratio of 10.43 as of fiscal year 2025, which is generally considered healthy.
What is Uniqure's debt-to-equity ratio?
Uniqure (QURE) had a debt-to-equity ratio of 0.25 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Uniqure's return on assets (ROA)?
Uniqure (QURE) had a return on assets of -24.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is Uniqure's cash runway?
Based on fiscal year 2025 data, Uniqure (QURE) had $80.2M in cash against an annual operating cash burn of $178.0M. This gives an estimated cash runway of approximately 5 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.
What is Uniqure's Altman Z-Score?
Uniqure (QURE) has an Altman Z-Score of 0.82, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.
What is Uniqure's Piotroski F-Score?
Uniqure (QURE) has a Piotroski F-Score of 4 out of 9, indicating neutral financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Uniqure's earnings high quality?
Uniqure (QURE) has an earnings quality ratio of 0.89x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.
Can Uniqure cover its interest payments?
Uniqure (QURE) has an interest coverage ratio of -3.0x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.
How financially healthy is Uniqure?
Uniqure (QURE) scores 45 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.