Taysha Gene Therapies, Inc. (TSHA) Financials
A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 10, 2026; every other figure is from the SEC filings on this page. Not financial advice.
Newest figures come from the 10-Q for Q2 FY2026, filed Aug 11, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the TSHA SEC filings page.
Taysha Gene Therapies, Inc. (TSHA) reported $9.8M in revenue for fiscal year 2025, up 17.3% from the prior fiscal year. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 6 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).
The business remains development-stage: heavy R&D spending and recurring cash use are funded mainly through financing, not sales.
In FY2025, R&D was nearly 8.8x revenue, while operating cash flow was a$93.1M outflow. Because operating and free cash flow were nearly identical, the accounting loss is translating into cash use rather than being mainly a non-cash presentation effect.
The balance sheet expanded without a matching commercial base: total assets rose from
The supplied liquidity comparison equaled 41.2 months of the latest reported annual outflow, and the current ratio reached 12.2x; together, these describe substantial reported liquidity, not an operating model that funds itself. Free cash flow was a
Financial Health Signals
Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →
Health score ≠ stock price. This rates the quality of Taysha Gene Therapies, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.
Taysha Gene Therapies, Inc. held $319.8M in cash, cash equivalents and investments at the end of fiscal year 2025, and its operations used $93.1M of cash that year. Cash Runway ranks emerging companies on the size of that balance against the outflow behind it, and Taysha Gene Therapies, Inc. scores 64/100 among other emerging companies.
Taysha Gene Therapies, Inc. had 287M shares outstanding at the end of fiscal year 2025, against 205M in fiscal year 2024. Dilution ranks emerging companies on how fast that count has grown over three years, where a slower rise is the better one, and Taysha Gene Therapies, Inc. scores 32/100 among other emerging companies.
Taysha Gene Therapies, Inc. spent $86.4M on research and development in fiscal year 2025, which was 71.8% of its operating costs that year. R&D Intensity ranks emerging companies on the share of operating costs that goes into research, and Taysha Gene Therapies, Inc. scores 92/100 among other emerging companies.
Taysha Gene Therapies, Inc. reported revenue of $9.8M in fiscal year 2025, against $8.3M in fiscal year 2024. Revenue Progress ranks emerging companies on the three-year path of that line, and Taysha Gene Therapies, Inc. scores 19/100 among other emerging companies.
Taysha Gene Therapies, Inc.'s operations used $93.1M of cash in fiscal year 2025, against $81.2M used in fiscal year 2024. Burn Trend ranks emerging companies on which way that figure has moved over three years, and Taysha Gene Therapies, Inc. scores 33/100 among other emerging companies.
Taysha Gene Therapies, Inc.'s cash, cash equivalents and investments came to $319.8M at the end of fiscal year 2025, against $96.4M of total liabilities. Balance Sheet ranks emerging companies on that comparison, and Taysha Gene Therapies, Inc. scores 84/100 among other emerging companies.
Taysha Gene Therapies, Inc. scores 6.22, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($1.5B) relative to total liabilities ($96.4M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.
Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.
Taysha Gene Therapies, Inc. passes 4 of 8 computable financial strength tests (1 of the nine could not be computed from available data). 2 of 4 profitability signals pass, 2 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.
Taysha Gene Therapies, Inc. reported a net loss of $109.0M while operations used $93.1M of cash. With neither figure positive, the ratio between the two carries no quality signal.
Taysha Gene Therapies, Inc. reported an operating loss of $110.5M against $63K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations.
Key Financial Metrics
Earnings & Revenue
Taysha Gene Therapies, Inc. generated $0 in revenue in Q2 2026. This represents a decrease of 100.0% from the same quarter a year earlier.
Taysha Gene Therapies, Inc.'s EBITDA was -$46.9M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 77.5% from the same quarter a year earlier. Against the prior quarter it is down 8.7%.
Taysha Gene Therapies, Inc. reported -$46.6M in net income in Q2 2026. This represents a decrease of 73.5% from the same quarter a year earlier. Against the prior quarter it is down 10.0%.
Taysha Gene Therapies, Inc. earned -$0.13 per diluted share (EPS) in Q2 2026. This represents a decrease of 44.4% from the same quarter a year earlier. Against the prior quarter it is down 8.3%.
Cash & Balance Sheet
Taysha Gene Therapies, Inc. recorded an outflow of $40.4M in free cash flow in Q2 2026, representing a cash shortfall after capex. This represents a decrease of 100.3% from the same quarter a year earlier. Against the prior quarter it is up 1.2%.
Taysha Gene Therapies, Inc. held $455.4M in cash against $49.3M in long-term debt as of Q2 2026.
Not reported for Q2 2026.
Margins & Returns
Taysha Gene Therapies, Inc.'s ROE was -12.0% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is down 1.2 percentage points from the same quarter a year earlier. Against the prior quarter it is up 8.0 percentage points.
Not reported for Q2 2026.
Not reported for Q2 2026.
Not reported for Q2 2026.
Capital Allocation
Taysha Gene Therapies, Inc. invested $38.6M in research and development in Q2 2026. This represents an increase of 91.8% from the same quarter a year earlier. Against the prior quarter it is up 14.3%.
Taysha Gene Therapies, Inc. invested $1K in capex in Q2 2026, funding long-term assets and infrastructure. This represents a decrease of 50.0% from the same quarter a year earlier. Against the prior quarter it is down 95.8%.
Not reported for Q2 2026.
TSHA Income Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0-100.0% | $0-100.0% | N/A | $0-100.0% | $2.0M+78.6% | $2.3M-32.5% | $2.0M-43.9% | $1.8M-62.3% |
| R&D Expenses | $38.6M+91.8% | $33.8M+117.2% | N/A | $25.7M+72.3% | $20.1M+33.6% | $15.6M-24.7% | $15.3M+20.8% | $14.9M+26.8% |
| SG&A Expenses | $12.1M+41.3% | $9.7M+18.6% | N/A | $8.3M+4.8% | $8.6M+17.2% | $8.2M+15.2% | $6.6M-1.3% | $7.9M-8.0% |
| Operating Income | -$47.3M-77.0% | -$43.5M-103.0% | N/A | -$34.0M-31.4% | -$26.8M-25.6% | -$21.4M+12.0% | -$19.9M-22.7% | -$25.9M-59.4% |
| EBITDA | -$46.9M-77.5% | -$43.2M-104.3% | N/A | -$33.8M-32.1% | -$26.5M-26.0% | -$21.1M+11.9% | -$19.6M-23.3% | -$25.6M-60.5% |
| Interest Expense | $6K-64.7% | $9K-52.6% | N/A | $15K-37.5% | $17K-37.0% | $19K-34.5% | $22K-96.9% | $24K-98.4% |
| Income Tax | N/A | $0 | N/A | N/A | N/A | $0 | N/A | N/A |
| Net Income | -$46.6M-73.5% | -$42.4M-97.0% | N/A | -$32.7M-28.2% | -$26.9M-28.4% | -$21.5M+10.5% | -$18.8M-139.3% | -$25.5M+78.2% |
| EPS (Basic) | -$0.13-44.4% | -$0.12-50.0% | -$0.08-14.3% | -$0.09+10.0% | -$0.090.0% | -$0.08+20.0% | -$0.07-107.6% | -$0.10+89.2% |
| EPS (Diluted) | -$0.13-44.4% | -$0.12-50.0% | -$0.08-14.3% | -$0.09+10.0% | -$0.090.0% | -$0.08+20.0% | -$0.07 | -$0.10 |
| Diluted Shares (Avg) | 369M+23.8% | 367M+36.1% | N/A | 353M+31.9% | 298M+28.0% | 269M+16.5% | N/A | 268M |
Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.
TSHA Balance Sheet
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Total Assets | $470.4M+41.1% | $300.4M+117.1% | $343.3M+114.1% | $316.6M+75.7% | $333.3M+66.3% | $138.4M-9.6% | $160.4M-7.2% | $180.2M-7.9% |
| Current Assets | $461.4M+45.9% | $282.3M+133.8% | $324.6M+128.4% | $300.0M+85.7% | $316.3M+77.2% | $120.7M-7.6% | $142.1M-5.2% | $161.6M-6.0% |
| Cash & Equivalents | $455.4M+45.6% | $276.6M+137.2% | $319.8M+130.0% | $297.3M+88.6% | $312.8M+81.1% | $116.6M-6.0% | $139.0M-3.4% | $157.7M-4.0% |
| Short-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Long-Term Investments | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 |
| Total Liabilities | $83.2M-1.7% | $88.4M+6.1% | $96.4M+8.5% | $97.6M+6.7% | $84.6M-7.6% | $83.3M-16.0% | $88.8M-9.2% | $91.4M-62.7% |
| Current Liabilities | $26.0M+2.5% | $20.1M-10.9% | $26.6M+1.2% | $28.6M-2.4% | $25.3M-25.8% | $22.6M-41.6% | $26.2M-28.6% | $29.3M-83.7% |
| Non-Current Liabilities | $57.2M-3.5% | $68.3M+12.5% | $69.8M+11.5% | $68.9M+11.0% | $59.3M+3.3% | $60.7M+0.4% | $62.6M+2.6% | $62.1M-3.6% |
| Long-Term Debt | $49.3M+20.0% | $49.0M+15.3% | $50.1M+14.0% | $50.9M+18.3% | $41.1M+8.5% | $42.5M+4.8% | $43.9M+8.5% | $43.0M+11.5% |
| Total Equity | $387.3M+55.7% | $211.9M+284.9% | $246.9M+245.2% | $219.0M+146.6% | $248.7M+128.5% | $55.1M+2.2% | $71.5M-4.6% | $88.8M+280.8% |
| Retained Earnings | -$800.3M-23.0% | -$753.7M-20.8% | -$711.3M-18.1% | -$683.4M-17.1% | -$650.7M-16.6% | -$623.8M-16.2% | -$602.3M-17.4% | -$583.5M-4.1% |
Not reported in any period shown, so not listed: Inventory, Accounts Receivable, Goodwill.
TSHA Cash Flow Statement
Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Operating Cash Flow | -$40.4M-100.3% | -$40.9M-85.6% | -$26.7M-46.0% | -$24.2M-11.8% | -$20.2M+6.1% | -$22.0M-11.2% | -$18.3M-13.6% | -$21.6M-20.4% |
| Depreciation & Amortization | $400K+33.3% | $295K+4.2% | $299K-1.6% | $200K-33.3% | $300K0.0% | $283K-12.9% | $304K-16.9% | $300K0.0% |
| Stock-Based Compensation | $5.8M+82.1% | $5.5M+68.4% | N/A | $3.3M-2.1% | $3.2M-4.3% | $3.3M+3.0% | N/A | $3.4M+64.6% |
| Capital Expenditures | -$1K-50.0% | $24K-93.7% | $250K+12400.0% | $108K+208.6% | $2K-99.0% | $378K+170.0% | -$2K-88.2% | $35K |
| Free Cash Flow | -$40.4M-100.3% | -$40.9M-82.6% | -$27.0M-47.3% | -$24.3M-12.1% | -$20.2M+7.0% | -$22.4M-12.3% | -$18.3M-13.5% | -$21.6M-20.6% |
| Investing Cash Flow | $1K-98.4% | -$3.0M-715.1% | -$247K-2000.0% | -$48K-37.1% | $62K+130.8% | -$371K-165.0% | $13K+230.0% | -$35K+99.0% |
| Financing Cash Flow | $216.7M+0.2% | $711K+1467.3% | $49.6M+13981.2% | $8.8M+33.4% | $216.3M+206.9% | -$52K-136.4% | -$357K+91.6% | $6.6M-95.3% |
Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.
TSHA Financial Ratios
Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.
| Metric | Q2'2610-Q | Q1'2610-Q | Q4'2510-Q | Q3'2510-Q | Q2'2510-Q | Q1'2510-Q | Q4'2410-K | Q3'2410-Q |
|---|---|---|---|---|---|---|---|---|
| Operating Margin | N/A | N/A | N/A | N/A | -1347.1% | -930.5% | -985.8% | -1448.4% |
| Net Margin | N/A | N/A | N/A | N/A | -1353.6% | -935.2% | -929.0% | -1427.5% |
| Return on Equity | -12.0%-1.2pp | -20.0%+19.1pp | N/A | -14.9%+13.8pp | -10.8%+8.4pp | -39.1%+5.6pp | -26.3%-90.0pp | -28.7% |
| Return on Assets | -9.9%-1.8pp | -14.1%+1.4pp | N/A | -10.3%+3.8pp | -8.1%+2.4pp | -15.6%+0.2pp | -11.7%-39.3pp | -14.2%+45.6pp |
| Current Ratio | 17.76+5.3x | 14.04+8.7x | 12.23+6.8x | 10.48+5.0x | 12.48+7.3x | 5.35+2.0x | 5.42+1.3x | 5.51+4.6x |
| Debt-to-Equity | 0.130.0x | 0.23-0.5x | 0.20-0.4x | 0.23-0.3x | 0.17-0.2x | 0.770.0x | 0.61+0.1x | 0.48 |
| Asset Turnover | 0.000.0x | 0.000.0x | N/A | 0.000.0x | 0.010.0x | 0.020.0x | 0.010.0x | 0.010.0x |
| FCF Margin | N/A | N/A | N/A | N/A | -1016.3% | -973.0% | -905.5% | -1210.8% |
Not reported in any period shown, so not listed: Gross Margin.
Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.
Similar Companies
Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.
| Company | Fiscal year | Revenue | Net income | Net margin | Market cap | Health score |
|---|---|---|---|---|---|---|
| Taysha Gene Therapies, Inc. TSHA | FY2025 | $9.8M | -$109.0M | N/A | $1.5B | 54/100 |
| uniQure N.V. QURE | FY2025 | $16.1M | -$199.0M | N/A | $1.6B | 44/100 |
| Sana Biotechnology, Inc. SANA | FY2025 | N/A | -$244.2M | N/A | $835.2M | — |
| Upstream Bio, Inc. UPB | FY2025 | $2.9M | -$143.4M | N/A | $257.4M | 54/100 |
| EyePoint, Inc. EYPT | FY2025 | $31.4M | -$232.0M | N/A | $293.1M | 46/100 |
Where Taysha Gene Therapies, Inc. Ranks
Frequently Asked Questions
What is Taysha Gene Therapies, Inc.'s annual revenue?
Taysha Gene Therapies, Inc. (TSHA) reported $9.8M in total revenue for fiscal year 2025. This represents a 17.3% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.
How fast is Taysha Gene Therapies, Inc.'s revenue growing?
Taysha Gene Therapies, Inc. (TSHA) revenue grew by 17.3% year-over-year, from $8.3M to $9.8M in fiscal year 2025.
Is Taysha Gene Therapies, Inc. profitable?
No, Taysha Gene Therapies, Inc. (TSHA) reported a net income of -$109.0M in fiscal year 2025.
What is Taysha Gene Therapies, Inc.'s EBITDA?
Taysha Gene Therapies, Inc. (TSHA) had EBITDA of -$109.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.
How much debt does Taysha Gene Therapies, Inc. have?
As of fiscal year 2025, Taysha Gene Therapies, Inc. (TSHA) had $319.8M in cash and equivalents against $50.1M in long-term debt.
What is Taysha Gene Therapies, Inc.'s return on equity (ROE)?
Taysha Gene Therapies, Inc. (TSHA) has a return on equity of -44.1% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.
What is Taysha Gene Therapies, Inc.'s free cash flow?
Taysha Gene Therapies, Inc. (TSHA) recorded an outflow of $93.8M in free cash flow during fiscal year 2025. This represents a -15.0% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.
What is Taysha Gene Therapies, Inc.'s operating cash flow?
Taysha Gene Therapies, Inc. (TSHA) recorded an outflow of $93.1M in operating cash flow during fiscal year 2025, representing cash used by core business activities.
What are Taysha Gene Therapies, Inc.'s total assets?
Taysha Gene Therapies, Inc. (TSHA) had $343.3M in total assets as of fiscal year 2025, including both current and long-term assets.
What are Taysha Gene Therapies, Inc.'s capital expenditures?
Taysha Gene Therapies, Inc. (TSHA) invested $738K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.
How much does Taysha Gene Therapies, Inc. spend on research and development?
Taysha Gene Therapies, Inc. (TSHA) invested $86.4M in research and development during fiscal year 2025.
What is Taysha Gene Therapies, Inc.'s current ratio?
Taysha Gene Therapies, Inc. (TSHA) had a current ratio of 12.23 as of fiscal year 2025, which is generally considered healthy.
What is Taysha Gene Therapies, Inc.'s debt-to-equity ratio?
Taysha Gene Therapies, Inc. (TSHA) had a debt-to-equity ratio of 0.20 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.
What is Taysha Gene Therapies, Inc.'s return on assets (ROA)?
Taysha Gene Therapies, Inc. (TSHA) had a return on assets of -31.8% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.
What is Taysha Gene Therapies, Inc.'s P/E ratio?
Taysha Gene Therapies, Inc. (TSHA) has no price-to-earnings ratio at the moment: net loss, so no earnings multiple (FY2025). The market capitalization is $1.5B as of Oct 10, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.
What is Taysha Gene Therapies, Inc.'s price-to-sales ratio?
Taysha Gene Therapies, Inc. (TSHA) trades at 150x sales, its market capitalization divided by revenue of $9.8M revenue, FY2025. The market capitalization is $1.5B as of Oct 10, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.
How does Taysha Gene Therapies, Inc.'s liquidity compare with its operating cash outflow?
At the end of fiscal year 2025, Taysha Gene Therapies, Inc. (TSHA) held $319.8M in cash, cash equivalents and investments, and reported an operating cash outflow of $93.1M over that year. Dividing the one by the other, the reported balance equals about 41 months of the outflow reported that year. This is arithmetic over figures already filed, not a projection: it assumes nothing about future spending, financing or operations.
What is Taysha Gene Therapies, Inc.'s Altman Z-Score?
Taysha Gene Therapies, Inc. (TSHA) has an Altman Z-Score of 6.22, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.
What is Taysha Gene Therapies, Inc.'s Piotroski F-Score?
Taysha Gene Therapies, Inc. (TSHA) has a Piotroski F-Score of 4 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.
Are Taysha Gene Therapies, Inc.'s earnings high quality?
Taysha Gene Therapies, Inc. (TSHA) reported a net loss of $109.0M while operations used $93.1M of cash. With neither figure positive, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.
Can Taysha Gene Therapies, Inc. cover its interest payments?
Taysha Gene Therapies, Inc. (TSHA) reported an operating loss of $110.5M against $63K in interest expense. There is no operating profit to cover interest, so interest must be met from cash reserves or from financing rather than from operations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.
How financially healthy is Taysha Gene Therapies, Inc.?
Taysha Gene Therapies, Inc. (TSHA) scores 54 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.