Vestal Point reports 6.8% stake in uniQure (QURE) — 3.7M shares

Vestal Point Capital, LP and Ryan Wilder reported beneficial ownership of 3,700,000 ordinary shares of uniQure N.V., representing 6.8% of the outstanding class.

Rhea-AI Filing Summary

Vestal Point Capital, LP and Ryan Wilder reported beneficial ownership of 3,700,000 ordinary shares of uniQure N.V., representing 6.8% of the outstanding class. The shares are directly held by a Vestal Point-managed fund and a managed account; Mr. Wilder is the Chief Investment Officer and managing partner of the investment manager and reports shared voting and dispositive power over the shares. The percent calculation uses 54,748,496 ordinary shares outstanding as of May 6, 2025. The filing states the holdings were acquired in the ordinary course of business and not for the purpose of changing or influencing control of the issuer.

Positive

• Disclosure of a material stake (3,700,000 shares, 6.8%) provides transparency to the market
• Holdings reported as held in the ordinary course and not for control, allowing treatment as a passive investor under Schedule 13G

Negative

• None.

Insights

Securities Analyst

TL;DR: A 6.8% disclosed stake by an investment manager signals a meaningful position but is presented as non-control and held in the ordinary course.

The filing discloses that Vestal Point Capital, through a fund and account it manages, holds 3.7 million uniQure ordinary shares, equal to 6.8% of shares outstanding based on the companys May 6, 2025 share count. Shared voting and dispositive power are reported, with no sole voting or dispositive power. The statement emphasizes the positions were not acquired to influence control. For investors, a >5% ownership can lead to increased attention and potential engagement, but the filing contains no plans or proposals and does not indicate coordinated action beyond standard investment activity.

Corporate Governance Specialist

TL;DR: Reporting is standard for Schedule 13G/A; disclosure shows material ownership but affirms non-control intent.

The disclosure complies with Schedule 13G/A conventions: it identifies the reporting persons, their roles, the business address, and the exact share and voting/dispositive breakdowns. The certification states the holdings are in the ordinary course and not intended to change control, which preserves the Schedule 13G filing status rather than a more active Schedule 13D. This distinction matters for governance watchers because it suggests passive ownership absent further filings or public statements.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many uniQure (QURE) shares does Vestal Point Capital report owning?

The filing reports 3,700,000 ordinary shares, representing 6.8% of the class.

Who else is named on the Schedule 13G/A filing for QURE?

The filing names Vestal Point Capital, LP as the investment manager and Ryan Wilder (CIO and Managing Partner) as an individual reporting person.

What voting and dispositive power is reported over the QURE shares?

The reporting persons state 0 sole voting power and 3,700,000 shared voting and shared dispositive power; sole dispositive power is 0.

What share count was used to calculate the 6.8% ownership for QURE?

The percentage is based on 54,748,496 ordinary shares outstanding as of May 6, 2025, per the company's quarterly report.

Does the filing indicate Vestal Point intends to influence control of uniQure?

No. The certification states the shares were not acquired and are not held for the purpose of changing or influencing control of the issuer.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 08/14/2025 - 04:03 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 4)

uniQure N.V.

(Name of Issuer)

Ordinary Shares, par value 0.05 euro per share

(Title of Class of Securities)

N90064101

(CUSIP Number)

06/30/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No. N90064101

1

Names of Reporting Persons

Vestal Point Capital, LP

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 3,700,000.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 3,700,000.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

3,700,000.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.8 %

12

Type of Reporting Person (See Instructions)

IA, PN

SCHEDULE 13G

CUSIP No. N90064101

1

Names of Reporting Persons

Ryan Wilder

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 3,700,000.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 3,700,000.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

3,700,000.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

6.8 %

12

Type of Reporting Person (See Instructions)

HC, IN

SCHEDULE 13G

Item 1.
(a)	Name of issuer: uniQure N.V.
(b)	Address of issuer's principal executive offices: Paasheuvelweg 25a, 1105 BP Amsterdam, The Netherlands
Item 2.
(a)	Name of person filing: This statement is filed by: (i) Vestal Point Capital, LP (the "Investment Manager"), a Delaware limited partnership, and the investment adviser to a certain fund and a managed account (the "Vestal Point Fund and Account"), with respect to the ordinary shares, par value 0.05 euro per share (the "Ordinary Shares"), of uniQure N.V. (the "Company") directly held by the Vestal Point Fund and Account; and (ii) Mr. Ryan Wilder ("Mr. Wilder"), the Chief Investment Officer and Managing Partner of the Investment Manager and the Managing Member of Vestal Point Capital, LLC, the general partner of the Investment Manager, with respect to the Ordinary Shares directly held by the Vestal Point Fund and Account. The foregoing persons are hereinafter sometimes collectively referred to as the "Reporting Persons." The filing of this statement should not be construed as an admission that any of the foregoing persons or any Reporting Person is, for the purposes of Section 13 of the Securities Exchange Act of 1934, the beneficial owner of the securities reported herein.
(b)	Address or principal business office or, if none, residence: The address of the business office of each of the Reporting Persons is 632 Broadway, Suite 602, New York, NY 10012.
(c)	Citizenship: The Investment Manager is a Delaware limited partnership. Mr. Wilder is a citizen of the United States.
(d)	Title of class of securities: Ordinary Shares, par value 0.05 euro per share
(e)	CUSIP No.: N90064101
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: The information required by Item 4(a) is set forth in Row 9 of the cover page for each of the Reporting Persons and is incorporated herein by reference. The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 54,748,496 Ordinary Shares outstanding as of May 6, 2025, as reported in the Company's Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2025, filed with the Securities and Exchange Commission on May 9, 2025.
(b)	Percent of class: 6.8%
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
	(ii) Shared power to vote or to direct the vote: The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
	(iii) Sole power to dispose or to direct the disposition of: The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
	(iv) Shared power to dispose or to direct the disposition of: The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for each of the Reporting Persons and is incorporated herein by reference.
Item 5.	Ownership of 5 Percent or Less of a Class.
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. See Item 2(a). The Vestal Point Fund and Account have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Ordinary Shares reported herein.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	Not Applicable
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Vestal Point Capital, LP

Signature:	/s/ Ryan Wilder
Name/Title:	By: Vestal Point Capital, LLC, General Partner, By: Ryan Wilder, Chief Investment Officer and Managing Partner
Date:	08/14/2025

Ryan Wilder

Signature:	/s/ Ryan Wilder
Name/Title:	Ryan Wilder, Individually
Date:	08/14/2025